screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects
Bramsen, Jesper B, Pakula, Malgorzata M, Hansen, Thomas B, Bus, Claus, Langkjær, Niels, Odadzic, Dalibor, Smicius, Romualdas, Wengel, Suzy L, Chattopadhyaya, Jyoti, Engels, Joachim W, Herdewijn, Piet, Wengel, Jesper, Kjems, Jørgen
Published in Nucleic acids research (01.09.2010)
Published in Nucleic acids research (01.09.2010)
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Journal Article
Synthesis of Conformationally Locked Carba-LNAs through Intramolecular Free-Radical Addition to CN. Electrostatic and Steric Implication of the Carba-LNA Substituents in the Modified Oligos for Nuclease and Thermodynamic Stabilities
Xu, Jianfeng, Liu, Yi, Dupouy, Christelle, Chattopadhyaya, Jyoti
Published in Journal of organic chemistry (04.09.2009)
Published in Journal of organic chemistry (04.09.2009)
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Journal Article
Fine Tuning of Electrostatics around the Internucleotidic Phosphate through Incorporation of Modified 2′,4′-Carbocyclic-LNAs and -ENAs Leads to Significant Modulation of Antisense Properties
Zhou, Chuanzheng, Liu, Yi, Andaloussi, Mounir, Badgujar, Naresh, Plashkevych, Oleksandr, Chattopadhyaya, Jyoti
Published in Journal of organic chemistry (02.01.2009)
Published in Journal of organic chemistry (02.01.2009)
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Journal Article
Conformationally-constrained indeno[2,1-c]quinolines - a new class of anti-mycobacterial agents
Upadhayaya, Ram Shankar, Lahore, Santosh V., Sayyed, Aftab Y., Dixit, Shailesh S., Shinde, Popat D., Chattopadhyaya, Jyoti
Published in Organic & biomolecular chemistry (01.01.2010)
Published in Organic & biomolecular chemistry (01.01.2010)
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Journal Article
Allele-selective inhibition of ataxin-3 (ATX3) expression by antisense oligomers and duplex RNAs
Hu, Jiaxin, Gagnon, Keith T., Liu, Jing, Watts, Jonathan K., Syeda-Nawaz, Jeja, Bennett, C. Frank, Swayze, Eric E., Randolph, John, Chattopadhyaya, Jyoti, Corey, David R.
Published in Biological chemistry (01.04.2011)
Published in Biological chemistry (01.04.2011)
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Journal Article
Synthesis and antimycobacterial activity of prodrugs of indeno[2,1- c]quinoline derivatives
Upadhayaya, Ram Shankar, Shinde, Popat D., Kadam, Sandip A., Bawane, Amit N., Sayyed, Aftab Y., Kardile, Ramakant A., Gitay, Pallavi N., Lahore, Santosh V., Dixit, Shailesh S., Földesi, András, Chattopadhyaya, Jyoti
Published in European journal of medicinal chemistry (01.04.2011)
Published in European journal of medicinal chemistry (01.04.2011)
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Journal Article
Significant pKa Perturbation of Nucleobases Is an Intrinsic Property of the Sequence Context in DNA and RNA
ACHARYA, Sandipta, BARMAN, Jharna, CHERUKU, Pradeep, CHATTERJEE, Subhrangsu, ACHARYA, Parag, ISAKSSON, Johan, CHATTOPADHYAYA, Jyoti
Published in Journal of the American Chemical Society (21.07.2004)
Published in Journal of the American Chemical Society (21.07.2004)
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Journal Article
The pKa's of 2‘-Hydroxyl Group in Nucleosides and Nucleotides
VELIKYAN, Irina, ACHARYA, Sandipta, TRIFONOVA, Anna, FöLDESI, Andras, CHATTOPADHYAYA, Jyoti
Published in Journal of the American Chemical Society (28.03.2001)
Published in Journal of the American Chemical Society (28.03.2001)
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Journal Article
In vivo efficacy and off-target effects of Locked Nucleic Acid (LNA) and Unlocked Nucleic Acid (UNA) modified siRNA and small internally segmented interfering RNA (sisiRNA) in mice bearing human tumor xenografts
Mook, O.R., Vreijling, Jeroen, Wengel, Suzy, Wengel, Jesper, Zhou, Chuanzheng, Chattopadhyaya, Jyoti, Baas, Frank, Fluiter, Kees
Published in Artificial DNA, PNA & XNA (01.07.2010)
Published in Artificial DNA, PNA & XNA (01.07.2010)
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Journal Article
Facile preparation of the oxetane-nucleosides
Bogucka, M, Naus, P, Pathmasiri, W, Barman, J, Chattopadhyaya, J
Published in Organic & biomolecular chemistry (21.12.2005)
Published in Organic & biomolecular chemistry (21.12.2005)
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Journal Article
High-quality oligo-RNA synthesis using the new 2′-O-TEM protecting group by selectively quenching the addition of p-tolyl vinyl sulphone to exocyclic amino functions
Zhou, Chuanzheng, Pathmasiri, Wimal, Honcharenko, Dmytro, Chatterjee, Subhrangsu, Barman, Jharna, Chattopadhyaya, Jyoti
Published in Canadian journal of chemistry (01.04.2007)
Published in Canadian journal of chemistry (01.04.2007)
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Journal Article
Non-identical electronic characters of the internucleotidic phosphates in RNA modulate the chemical reactivity of the phosphodiester bonds
Barman, Jharna, Acharya, Sandipta, Zhou, Chuanzheng, Chatterjee, Subhrangsu, Engström, Ake, Chattopadhyaya, Jyoti
Published in Organic & biomolecular chemistry (01.01.2006)
Published in Organic & biomolecular chemistry (01.01.2006)
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Journal Article
Stereoisomeric Selectivity of Human Deoxyribonucleoside Kinases
Wang, Jianghai, Choudhury, Devapriya, Chattopadhyaya, Jyoti, Eriksson, Staffan
Published in Biochemistry (Easton) (21.12.1999)
Published in Biochemistry (Easton) (21.12.1999)
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