Specific Mutations in APC, but Not Alterations in DNA Damage Response, Associate With Outcomes of Patients With Metastatic Colorectal Cancer
Mondaca, Sebastian, Walch, Henry, Nandakumar, Subhiksha, Chatila, Walid K., Schultz, Nikolaus, Yaeger, Rona
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2020)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2020)
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Journal Article
Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer
Yaeger, Rona, Chatila, Walid K., Lipsyc, Marla D., Hechtman, Jaclyn F., Cercek, Andrea, Sanchez-Vega, Francisco, Jayakumaran, Gowtham, Middha, Sumit, Zehir, Ahmet, Donoghue, Mark T.A., You, Daoqi, Viale, Agnes, Kemeny, Nancy, Segal, Neil H., Stadler, Zsofia K., Varghese, Anna M., Kundra, Ritika, Gao, Jianjiong, Syed, Aijazuddin, Hyman, David M., Vakiani, Efsevia, Rosen, Neal, Taylor, Barry S., Ladanyi, Marc, Berger, Michael F., Solit, David B., Shia, Jinru, Saltz, Leonard, Schultz, Nikolaus
Published in Cancer cell (08.01.2018)
Published in Cancer cell (08.01.2018)
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Journal Article
First-line pembrolizumab and trastuzumab in HER2-positive oesophageal, gastric, or gastro-oesophageal junction cancer: an open-label, single-arm, phase 2 trial
Janjigian, Yelena Y, Maron, Steven B, Chatila, Walid K, Millang, Brittanie, Chavan, Shweta S, Alterman, Carly, Chou, Joanne F, Segal, Michal F, Simmons, Marc Z, Momtaz, Parisa, Shcherba, Marina, Ku, Geoffrey Y, Zervoudakis, Alice, Won, Elizabeth S, Kelsen, David P, Ilson, David H, Nagy, Rebecca J, Lanman, Richard B, Ptashkin, Ryan N, Donoghue, Mark T A, Capanu, Marinela, Taylor, Barry S, Solit, David B, Schultz, Nikolaus, Hechtman, Jaclyn F
Published in The lancet oncology (01.06.2020)
Published in The lancet oncology (01.06.2020)
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Journal Article
Cancer-associated mutations in DICER1 RNase IIIa and IIIb domains exert similar effects on miRNA biogenesis
Vedanayagam, Jeffrey, Chatila, Walid K, Aksoy, Bülent Arman, Majumdar, Sonali, Skanderup, Anders Jacobsen, Demir, Emek, Schultz, Nikolaus, Sander, Chris, Lai, Eric C
Published in Nature communications (15.08.2019)
Published in Nature communications (15.08.2019)
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Journal Article
Comparison of optomotor and optokinetic reflexes in mice
Kretschmer, Friedrich, Tariq, Momina, Chatila, Walid, Wu, Beverly, Badea, Tudor Constantin
Published in Journal of neurophysiology (01.07.2017)
Published in Journal of neurophysiology (01.07.2017)
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Journal Article
Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis
Li, Jun, Duran, Mercedes A, Dhanota, Ninjit, Chatila, Walid K, Bettigole, Sarah E, Kwon, John, Sriram, Roshan K, Humphries, Matthew P, Salto-Tellez, Manuel, James, Jacqueline A, Hanna, Matthew G, Melms, Johannes C, Vallabhaneni, Sreeram, Litchfield, Kevin, Usaite, Ieva, Biswas, Dhruva, Bareja, Rohan, Li, Hao Wei, Martin, Maria Laura, Dorsaint, Princesca, Cavallo, Julie-Ann, Li, Peng, Pauli, Chantal, Gottesdiener, Lee, DiPardo, Benjamin J, Hollmann, Travis J, Merghoub, Taha, Wen, Hannah Y, Reis-Filho, Jorge S, Riaz, Nadeem, Su, Shin-San Michael, Kalbasi, Anusha, Vasan, Neil, Powell, Simon N, Wolchok, Jedd D, Elemento, Olivier, Swanton, Charles, Shoushtari, Alexander N, Parkes, Eileen E, Izar, Benjamin, Bakhoum, Samuel F
Published in Cancer discovery (01.05.2021)
Published in Cancer discovery (01.05.2021)
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Journal Article
Lung-only melanoma: UV mutational signature supports origin from occult cutaneous primaries and argues against the concept of primary pulmonary melanoma
Yang, Chen, Sanchez-Vega, Francisco, Chang, Jason C., Chatila, Walid K., Shoushtari, Alexander N., Ladanyi, Marc, Travis, William D., Busam, Klaus J., Rekhtman, Natasha
Published in Modern pathology (01.11.2020)
Published in Modern pathology (01.11.2020)
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Journal Article
A Comprehensive Comparison of Early-Onset and Average-Onset Colorectal Cancers
Cercek, Andrea, Chatila, Walid K, Yaeger, Rona, Walch, Henry, Fernandes, Gustavo Dos Santos, Krishnan, Asha, Palmaira, Lerie, Maio, Anna, Kemel, Yelena, Srinivasan, Preethi, Bandlamudi, Chaitanya, Salo-Mullen, Erin, Tejada, Prince R, Belanfanti, Kimeisha, Galle, Jesse, Joseph, Vijai, Segal, Neil, Varghese, Anna, Reidy-Lagunes, Diane, Shia, Jinru, Vakiani, Efsevia, Mondaca, Sebastian, Mendelsohn, Robin, Lumish, Melissa A, Steinruecke, Felix, Kemeny, Nancy, Connell, Louise, Ganesh, Karuna, Markowitz, Arnold, Nash, Garrett, Guillem, Jose, Smith, J Joshua, Paty, Phillip B, Zhang, Liying, Mandelker, Diana, Birsoy, Ozge, Robson, Mark, Offit, Kenneth, Taylor, Barry, Berger, Michael, Solit, David, Weiser, Martin, Saltz, Leonard B, Aguilar, Julio Garcia, Schultz, Nikolaus, Diaz, Luis A, Stadler, Zsofia K
Published in JNCI : Journal of the National Cancer Institute (29.11.2021)
Published in JNCI : Journal of the National Cancer Institute (29.11.2021)
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Journal Article
Clinical and Molecular Predictors of Response to Immune Checkpoint Inhibitors in Patients with Advanced Esophagogastric Cancer
Greally, Megan, Chou, Joanne F, Chatila, Walid K, Margolis, Matthew, Capanu, Marinela, Hechtman, Jaclyn F, Tuvy, Yaelle, Kundra, Ritika, Daian, Foysal, Ladanyi, Marc, Kelsen, David P, Ilson, David H, Berger, Michael F, Tang, Laura H, Solit, David B, Diaz, Jr, Luis A, Schultz, Nikolaus, Janjigian, Yelena Y, Ku, Geoffrey Y
Published in Clinical cancer research (15.10.2019)
Published in Clinical cancer research (15.10.2019)
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Journal Article
Genomic and transcriptomic determinants of response to neoadjuvant therapy in rectal cancer
Chatila, Walid K, Kim, Jin K, Walch, Henry, Marco, Michael R, Chen, Chin-Tung, Wu, Fan, Omer, Dana M, Khalil, Danny N, Ganesh, Karuna, Qu, Xuan, Luthra, Anisha, Choi, Seo-Hyun, Ho, Yu-Jui, Kundra, Ritika, Groves, Katharine I, Chow, Oliver S, Cercek, Andrea, Weiser, Martin R, Widmar, Maria, Wei, Iris H, Pappou, Emmanouil P, Nash, Garrett M, Paty, Philip B, Shi, Qian, Vakiani, Efsevia, Duygu Selcuklu, S, Donoghue, Mark T A, Solit, David B, Berger, Michael F, Shia, Jinru, Pelossof, Raphael, Romesser, Paul B, Yaeger, Rona, Smith, J Joshua, Schultz, Nikolaus, Sanchez-Vega, Francisco, Garcia-Aguilar, Julio
Published in Nature medicine (01.08.2022)
Published in Nature medicine (01.08.2022)
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Journal Article
Cooperative genomic lesions in HRAS-mutant cancers predict resistance to farnesyltransferase inhibitors
Nigam, Aradhya, Krishnamoorthy, Gnana P, Chatila, Walid K, Berman, Katherine, Saqcena, Mahesh, Walch, Henry, Venkatramani, Mandakini, Ho, Alan L, Schultz, Nikolaus, Fagin, James A, Untch, Brian R
Published in Oncogene (06.09.2024)
Published in Oncogene (06.09.2024)
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Journal Article
Molecular and Clinical Determinants of Acquired Resistance and Treatment Duration for Targeted Therapies in Colorectal Cancer
Harrold, Emily, Keane, Fergus, Walch, Henry, Chou, Joanne F, Sinopoli, Jenna, Palladino, Silvia, Al-Rawi, Duaa H, Chadalavada, Kalyani, Manca, Paolo, Chalasani, Sree, Yang, Jessica, Cercek, Andrea, Shia, Jinru, Capanu, Marinela, Bakhoum, Samuel F, Schultz, Nikolaus, Chatila, Walid K, Yaeger, Rona
Published in Clinical cancer research (14.06.2024)
Published in Clinical cancer research (14.06.2024)
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Journal Article
Coaltered Ras/B-raf and TP53 Is Associated with Extremes of Survivorship and Distinct Patterns of Metastasis in Patients with Metastatic Colorectal Cancer
Datta, Jashodeep, Smith, J Joshua, Chatila, Walid K, McAuliffe, John C, Kandoth, Cyriac, Vakiani, Efsevia, Frankel, Timothy L, Ganesh, Karuna, Wasserman, Isaac, Lipsyc-Sharf, Marla, Guillem, Jose, Nash, Garrett M, Paty, Philip B, Weiser, Martin R, Saltz, Leonard B, Berger, Michael F, Jarnagin, William R, Balachandran, Vinod, Kingham, T Peter, Kemeny, Nancy E, Cercek, Andrea, Garcia-Aguilar, Julio, Taylor, Barry S, Viale, Agnes, Yaeger, Rona, Solit, David B, Schultz, Nikolaus, D'Angelica, Michael I
Published in Clinical cancer research (01.03.2020)
Published in Clinical cancer research (01.03.2020)
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Journal Article
Distinct Genomic Profiles are Associated With Conversion to Resection and Survival in Patients With Initially Unresectable Colorectal Liver Metastases Treated With Systemic and Hepatic Artery Chemotherapy
Datta, Jashodeep, Narayan, Raja R, Goldman, Debra A, Chatila, Walid K, Gonen, Mithat, Strong, James, Balachandran, Vinod P, Drebin, Jeffrey A, Kingham, T Peter, Jarnagin, William R, Schultz, Nikolaus, Kemeny, Nancy E, D'Angelica, Michael I
Published in Annals of surgery (01.11.2022)
Published in Annals of surgery (01.11.2022)
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Survival of Locally Advanced MSI-high Gastric Cancer Patients Treated With Perioperative Chemotherapy: A Retrospective Cohort Study
Vos, Elvira L, Maron, Steven B, Krell, Robert W, Nakauchi, Masaya, Fiasconaro, Megan, Capanu, Marinela, Walch, Henry S, Chatila, Walid K, Schultz, Nikolaus, Ilson, David H, Janjigian, Yelena Y, Ku, Geoffrey Y, Yoon, Sam S, Coit, Daniel G, Vanderbilt, Chad M, Tang, Laura H, Strong, Vivian E
Published in Annals of surgery (01.05.2023)
Published in Annals of surgery (01.05.2023)
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Journal Article
The genomic landscape of carcinomas with mucinous differentiation
Nguyen, Bastien, Sanchez-Vega, Francisco, Fong, Christopher J, Chatila, Walid K, Boroujeni, Amir Momeni, Pareja, Fresia, Weigelt, Britta, Sotiriou, Christos, Larsimont, Denis, Reis-Filho, Jorge S, Desmedt, Christine, Schultz, Nikolaus
Published in Scientific reports (04.05.2021)
Published in Scientific reports (04.05.2021)
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Journal Article
Optimal Strategy and Benefit of Pulsed Therapy Depend On Tumor Heterogeneity and Aggressiveness at Time of Treatment Initiation
Mathur, Deepti, Taylor, Bradford P, Chatila, Walid K, Scher, Howard I, Schultz, Nikolaus, Razavi, Pedram, Xavier, Joao B
Published in Molecular cancer therapeutics (04.05.2022)
Published in Molecular cancer therapeutics (04.05.2022)
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Journal Article
Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers
Chatila, Walid K, Walch, Henry, Hechtman, Jaclyn F, Moyer, Sydney M, Sgambati, Valeria, Faleck, David M, Srivastava, Amitabh, Tang, Laura, Benhamida, Jamal, Ismailgeci, Dorina, Campos, Carl, Wu, Fan, Chang, Qing, Vakiani, Efsevia, de Stanchina, Elisa, Weiser, Martin R, Widmar, Maria, Yantiss, Rhonda K, Shah, Manish A, Bass, Adam J, Stadler, Zsofia K, Katz, Lior H, Mellinghoff, Ingo K, Sethi, Nilay S, Schultz, Nikolaus, Ganesh, Karuna, Kelsen, David, Yaeger, Rona
Published in Nature communications (07.01.2023)
Published in Nature communications (07.01.2023)
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Journal Article
Therapeutic Implications of Detecting MAPK-Activating Alterations in Cutaneous and Unknown Primary Melanomas
Shoushtari, Alexander N, Chatila, Walid K, Arora, Arshi, Sanchez-Vega, Francisco, Kantheti, Havish S, Rojas Zamalloa, Jorge A, Krieger, Penina, Callahan, Margaret K, Betof Warner, Allison, Postow, Michael A, Momtaz, Parisa, Nair, Suresh, Ariyan, Charlotte E, Barker, Christopher A, Brady, Mary Susan, Coit, Daniel G, Rosen, Neal, Chapman, Paul B, Busam, Klaus J, Solit, David B, Panageas, Katherine S, Wolchok, Jedd D, Schultz, Nikolaus
Published in Clinical cancer research (15.04.2021)
Published in Clinical cancer research (15.04.2021)
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Journal Article
GABA Regulates Electrical Activity and Tumor Initiation in Melanoma
Tagore, Mohita, Hergenreder, Emiliano, Perlee, Sarah C, Cruz, Nelly M, Menocal, Laura, Suresh, Shruthy, Chan, Eric, Baron, Maayan, Melendez, Stephanie, Dave, Asim, Chatila, Walid K, Nsengimana, Jeremie, Koche, Richard P, Hollmann, Travis J, Ideker, Trey, Studer, Lorenz, Schietinger, Andrea, White, Richard M
Published in Cancer discovery (05.10.2023)
Published in Cancer discovery (05.10.2023)
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