Phosphodiesterase 10A Inhibitor Activity in Preclinical Models of the Positive, Cognitive, and Negative Symptoms of Schizophrenia
Grauer, Steven M, Pulito, Virginia L, Navarra, Rachel L, Kelly, Michele P, Kelley, Cody, Graf, Radka, Langen, Barbara, Logue, Sheree, Brennan, Julie, Jiang, Lixin, Charych, Erik, Egerland, Ute, Liu, Feng, Marquis, Karen L, Malamas, Michael, Hage, Thorsten, Comery, Thomas A, Brandon, Nicholas J
Published in The Journal of pharmacology and experimental therapeutics (01.11.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2009)
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Journal Article
Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer
Petros, Andrew M, Korepanova, Alla, Jakob, Clarissa G, Qiu, Wei, Panchal, Sanjay C, Wang, Jie, Dietrich, Justin D, Brewer, Jason T, Pohlki, Frauke, Kling, Andreas, Wilcox, Kyle, Lakics, Viktor, Bahnassawy, Lamiaa, Reinhardt, Peter, Partha, Sarathy Karunan, Bodelle, Pierre M, Lake, Marc, Charych, Erik I, Stoll, Vincent S, Sun, Chaohong, Mohler, Eric G
Published in Journal of medicinal chemistry (25.04.2019)
Published in Journal of medicinal chemistry (25.04.2019)
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Journal Article
Interplay of palmitoylation and phosphorylation in the trafficking and localization of phosphodiesterase 10A: implications for the treatment of schizophrenia
Charych, Erik I, Jiang, Li-Xin, Lo, Frederick, Sullivan, Kelly, Brandon, Nicholas J
Published in The Journal of neuroscience (07.07.2010)
Published in The Journal of neuroscience (07.07.2010)
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Journal Article
Activity-Independent Regulation of Dendrite Patterning by Postsynaptic Density Protein PSD-95
Charych, Erik I, Akum, Barbara F, Goldberg, Joshua S, Jornsten, Rebecka J, Rongo, Christopher, Zheng, James Q, Firestein, Bonnie L
Published in The Journal of neuroscience (04.10.2006)
Published in The Journal of neuroscience (04.10.2006)
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Journal Article
Increased expression in dorsolateral prefrontal cortex of CAPON in schizophrenia and bipolar disorder
Xu, Bin, Wratten, Naomi, Charych, Erik I, Buyske, Steven, Firestein, Bonnie L, Brzustowicz, Linda M
Published in PLoS medicine (01.10.2005)
Published in PLoS medicine (01.10.2005)
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Journal Article
PSD-95 alters microtubule dynamics via an association with EB3
Sweet, Eric S, Previtera, Michelle L, Fernández, Jose R, Charych, Erik I, Tseng, Chia-Yi, Kwon, Munjin, Starovoytov, Valentin, Zheng, James Q, Firestein, Bonnie L
Published in The Journal of neuroscience (19.01.2011)
Published in The Journal of neuroscience (19.01.2011)
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Journal Article
The brefeldin A-inhibited GDP/GTP exchange factor 2, a protein involved in vesicular trafficking, interacts with the beta subunits of the GABA receptors
Charych, Erik I, Yu, Wendou, Miralles, Celia P, Serwanski, David R, Li, Xuejing, Rubio, Maria, De Blas, Angel L
Published in Journal of neurochemistry (01.07.2004)
Published in Journal of neurochemistry (01.07.2004)
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Journal Article
Assessing the role of endooligopeptidase activity of Ndel1 (nuclear-distribution gene E homolog like-1) in neurite outgrowth
Hayashi, Mirian A.F., Guerreiro, Juliano R., Charych, Erik, Kamiya, Atsushi, Barbosa, Rosicler L., Machado, Maurício F., Campeiro, Joana D., Oliveira, Vitor, Sawa, Akira, Camargo, Antonio C.M., Brandon, Nicholas J.
Published in Molecular and cellular neuroscience (01.08.2010)
Published in Molecular and cellular neuroscience (01.08.2010)
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Journal Article
A Four PDZ Domain-containing Splice Variant Form of GRIP1 Is Localized in GABAergic and Glutamatergic Synapses in the Brain
Charych, Erik I., Yu, Wendou, Li, Rongwen, Serwanski, David R., Miralles, Celia P., Li, Xuejing, Yang, Bih Y., Pinal, Noelia, Walikonis, Randall, De Blas, Angel L.
Published in The Journal of biological chemistry (10.09.2004)
Published in The Journal of biological chemistry (10.09.2004)
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Journal Article
GRIP1 in GABAergic synapses
Li, Rong-Wen, Serwanski, David R., Miralles, Celia P., Li, Xuejing, Charych, Erik, Riquelme, Raquel, Huganir, Richard L., de Blas, Angel L.
Published in Journal of comparative neurology (1911) (18.07.2005)
Published in Journal of comparative neurology (1911) (18.07.2005)
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Journal Article
The brefeldin A‐inhibited GDP/GTP exchange factor 2, a protein involved in vesicular trafficking, interacts with the β subunits of the GABAA receptors
Charych, Erik I., Yu, Wendou, Miralles, Celia P., Serwanski, David R., Li, Xuejing, Rubio, Maria, De Blas, Angel L.
Published in Journal of neurochemistry (01.07.2004)
Published in Journal of neurochemistry (01.07.2004)
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Journal Article
Biallelic Mutations in PDE10A Lead to Loss of Striatal PDE10A and a Hyperkinetic Movement Disorder with Onset in Infancy
Diggle, Christine P., Sukoff Rizzo, Stacey J., Popiolek, Michael, Hinttala, Reetta, Schülke, Jan-Philip, Kurian, Manju A., Carr, Ian M., Markham, Alexander F., Bonthron, David T., Watson, Christopher, Sharif, Saghira Malik, Reinhart, Veronica, James, Larry C., Vanase-Frawley, Michelle A., Charych, Erik, Allen, Melanie, Harms, John, Schmidt, Christopher J., Ng, Joanne, Pysden, Karen, Strick, Christine, Vieira, Päivi, Mankinen, Katariina, Kokkonen, Hannaleena, Kallioinen, Matti, Sormunen, Raija, Rinne, Juha O., Johansson, Jarkko, Alakurtti, Kati, Huilaja, Laura, Hurskainen, Tiina, Tasanen, Kaisa, Anttila, Eija, Marques, Tiago Reis, Howes, Oliver, Politis, Marius, Fahiminiya, Somayyeh, Nguyen, Khanh Q., Majewski, Jacek, Uusimaa, Johanna, Sheridan, Eamonn, Brandon, Nicholas J.
Published in American journal of human genetics (07.04.2016)
Published in American journal of human genetics (07.04.2016)
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Journal Article
Kynurenines in CNS disease: regulation by inflammatory cytokines
Campbell, Brian M, Charych, Erik, Lee, Anna W, Möller, Thomas
Published in Frontiers in neuroscience (06.02.2014)
Published in Frontiers in neuroscience (06.02.2014)
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Journal Article
d-Amino Acid Oxidase Activity Is Inhibited by an Interaction with Bassoon Protein at the Presynaptic Active Zone
Popiolek, Michael, Ross, John F., Charych, Erik, Chanda, Pranab, Gundelfinger, Eckart D., Moss, Stephen J., Brandon, Nicholas J., Pausch, Mark H.
Published in The Journal of biological chemistry (19.08.2011)
Published in The Journal of biological chemistry (19.08.2011)
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Journal Article
Ndel1 alters its conformation by sequestering cAMP-specific phosphodiesterase-4D3 (PDE4D3) in a manner that is dynamically regulated through Protein Kinase A (PKA)
Collins, Daniel M., Murdoch, Hannah, Dunlop, Allan J., Charych, Erik, Baillie, George S., Wang, Qi, Herberg, Friedrich W., Brandon, Nicholas, Prinz, Anke, Houslay, Miles D.
Published in Cellular signalling (01.12.2008)
Published in Cellular signalling (01.12.2008)
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