Non-BRCA DNA Damage Repair Gene Alterations and Response to the PARP Inhibitor Rucaparib in Metastatic Castration-Resistant Prostate Cancer: Analysis From the Phase II TRITON2 Study
Abida, Wassim, Campbell, David, Patnaik, Akash, Shapiro, Jeremy D, Sautois, Brieuc, Vogelzang, Nicholas J, Voog, Eric G, Bryce, Alan H, McDermott, Ray, Ricci, Francesco, Rowe, Julie, Zhang, Jingsong, Piulats, Josep Maria, Fizazi, Karim, Merseburger, Axel S, Higano, Celestia S, Krieger, Laurence E, Ryan, Charles J, Feng, Felix Y, Simmons, Andrew D, Loehr, Andrea, Despain, Darrin, Dowson, Melanie, Green, Foad, Watkins, Simon P, Golsorkhi, Tony, Chowdhury, Simon
Published in Clinical cancer research (01.06.2020)
Published in Clinical cancer research (01.06.2020)
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Inhibiting Histone Deacetylase as a Means to Reverse Resistance to Angiogenesis Inhibitors: Phase I Study of Abexinostat Plus Pazopanib in Advanced Solid Tumor Malignancies
Aggarwal, Rahul, Thomas, Scott, Pawlowska, Nela, Bartelink, Imke, Grabowsky, Jennifer, Jahan, Thierry, Cripps, Amy, Harb, Armand, Leng, Jim, Reinert, Anne, Mastroserio, Ilaria, Truong, Thach-Giao, Ryan, Charles J, Munster, Pamela N
Published in Journal of clinical oncology (10.04.2017)
Published in Journal of clinical oncology (10.04.2017)
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Phase 2 Study of the Safety and Antitumor Activity of Apalutamide (ARN-509), a Potent Androgen Receptor Antagonist, in the High-risk Nonmetastatic Castration-resistant Prostate Cancer Cohort
Smith, Matthew R, Antonarakis, Emmanuel S, Ryan, Charles J, Berry, William R, Shore, Neal D, Liu, Glenn, Alumkal, Joshi J, Higano, Celestia S, Chow Maneval, Edna, Bandekar, Rajesh, de Boer, Carla J, Yu, Margaret K, Rathkopf, Dana E
Published in European urology (01.12.2016)
Published in European urology (01.12.2016)
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Phase I Clinical Trial of the CYP17 Inhibitor Abiraterone Acetate Demonstrating Clinical Activity in Patients With Castration-Resistant Prostate Cancer Who Received Prior Ketoconazole Therapy
Ryan, Charles J, Smith, Matthew R, Fong, Lawrence, Rosenberg, Jonathan E, Kantoff, Philip, Raynaud, Florence, Martins, Vanessa, Lee, Gloria, Kheoh, Thian, Kim, Jennifer, Molina, Arturo, Small, Eric J
Published in Journal of clinical oncology (20.03.2010)
Published in Journal of clinical oncology (20.03.2010)
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Radiographic progression-free survival as a response biomarker in metastatic castration-resistant prostate cancer: COU-AA-302 results
Morris, Michael J, Molina, Arturo, Small, Eric J, de Bono, Johann S, Logothetis, Christopher J, Fizazi, Karim, de Souza, Paul, Kantoff, Philip W, Higano, Celestia S, Li, Jinhui, Kheoh, Thian, Larson, Steven M, Matheny, Shannon L, Naini, Vahid, Burzykowski, Tomasz, Griffin, Thomas W, Scher, Howard I, Ryan, Charles J
Published in Journal of clinical oncology (20.04.2015)
Published in Journal of clinical oncology (20.04.2015)
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Journal Article
Phase II Multicenter Study of Abiraterone Acetate Plus Prednisone Therapy in Patients With Docetaxel-Treated Castration-Resistant Prostate Cancer
DANILA, Daniel C, MORRIS, Michael J, MOLINA, Arturo, ANAND, Aseem, KOSCUISZKA, Michael, LARSON, Steve M, SCHWARTZ, Lawrence H, FLEISHER, Martin, SCHER, Howard I, DE BONO, Johann S, RYAN, Charles J, DENMEADE, Samuel R, SMITH, Matthew R, TAPLIN, Mary-Ellen, BUBLEY, Glenn J, KHEOH, Thian, HAQQ, Christopher
Published in Journal of clinical oncology (20.03.2010)
Published in Journal of clinical oncology (20.03.2010)
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Journal Article
Significant and Sustained Antitumor Activity in Post-Docetaxel, Castration-Resistant Prostate Cancer With the CYP17 Inhibitor Abiraterone Acetate
Reid, Alison H M, Attard, Gerhardt, Danila, Daniel C, Oommen, Nikhil Babu, Olmos, David, Fong, Peter C, Molife, L Rhoda, Hunt, Joanne, Messiou, Christina, Parker, Christopher, Dearnaley, David, Swennenhuis, Joost F, Terstappen, Leon W M M, Lee, Gloria, Kheoh, Thian, Molina, Arturo, Ryan, Charles J, Small, Eric, Scher, Howard I, de Bono, Johann S
Published in Journal of clinical oncology (20.03.2010)
Published in Journal of clinical oncology (20.03.2010)
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Journal Article
Serum Androgens As Prognostic Biomarkers in Castration-Resistant Prostate Cancer: Results From an Analysis of a Randomized Phase III Trial
RYAN, Charles J, MOLINA, Arturo, JINHUI LI, THIAN KHEOH, SMALL, Eric J, HAQQ, Christopher M, GRANT, Russell P, DE BONO, Johann S, SCHER, Howard I
Published in Journal of clinical oncology (01.08.2013)
Published in Journal of clinical oncology (01.08.2013)
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Journal Article
Abiraterone acetate plus prednisone versus prednisone alone in chemotherapy-naive men with metastatic castration-resistant prostate cancer: patient-reported outcome results of a randomised phase 3 trial
Basch, Ethan, Dr, Autio, Karen, MD, Ryan, Charles J, MD, Mulders, Peter, Prof, Shore, Neal, MD, Kheoh, Thian, PhD, Fizazi, Karim, Prof, Logothetis, Christopher J, Prof, Rathkopf, Dana, MD, Smith, Matthew R, Prof, Mainwaring, Paul N, MD, Hao, Yanni, PhD, Griffin, Thomas, MD, Li, Susan, PhD, Meyers, Michael L, MD, Molina, Arturo, MD, Cleeland, Charles, Prof
Published in The lancet oncology (01.11.2013)
Published in The lancet oncology (01.11.2013)
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Journal Article
Clinical outcomes in patients with metastatic castrate‐resistant prostate cancer treated with abiraterone with or without ongoing androgen deprivation therapy: A retrospective case–control study
Arafa, Ali T., Blader, Leah R., Ramakrishna, Karan, Engle, Jeff, Ryan, Charles J., Zorko, Nicholas A., Jha, Gautam, Antonarakis, Emmanuel S.
Published in The Prostate (01.09.2023)
Published in The Prostate (01.09.2023)
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Journal Article
Correlation between Prostate-Specific Antigen Kinetics and Overall Survival in Abiraterone Acetate-Treated Castration-Resistant Prostate Cancer Patients
Xu, Xu S, Ryan, Charles J, Stuyckens, Kim, Smith, Matthew R, Saad, Fred, Griffin, Thomas W, Park, Youn C, Yu, Margaret K, Vermeulen, An, Poggesi, Italo, Nandy, Partha
Published in Clinical cancer research (15.07.2015)
Published in Clinical cancer research (15.07.2015)
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Journal Article
Impact of Baseline Corticosteroids on Survival and Steroid Androgens in Metastatic Castration-resistant Prostate Cancer: Exploratory Analysis from COU-AA-301
Montgomery, Bruce, Kheoh, Thian, Molina, Arturo, Li, Jinhui, Bellmunt, Joaquim, Tran, NamPhuong, Loriot, Yohann, Efstathiou, Eleni, Ryan, Charles J, Scher, Howard I, de Bono, Johann S
Published in European urology (01.05.2015)
Published in European urology (01.05.2015)
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Journal Article
HSD3B1 and Response to a Nonsteroidal CYP17A1 Inhibitor in Castration-Resistant Prostate Cancer
Almassi, Nima, Reichard, Chad, Li, Jianbo, Russell, Carly, Perry, Jaselle, Ryan, Charles J, Friedlander, Terence, Sharifi, Nima
Published in JAMA oncology (01.04.2018)
Published in JAMA oncology (01.04.2018)
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Journal Article
Common Structural and Epigenetic Changes in the Genome of Castration-Resistant Prostate Cancer
FRIEDLANDER, Terence W, ROY, Ritu, RYAN, Charles J, PARIS, Pamela L, TOMLINS, Scott A, NGO, Vy T, KOBAYASHI, Yasuko, AZAMEERA, Aruna, RUBIN, Mark A, PIENTA, Kenneth J, CHINNAIYAN, Arul, ITTMANN, Michael M
Published in Cancer research (Chicago, Ill.) (01.02.2012)
Published in Cancer research (Chicago, Ill.) (01.02.2012)
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Journal Article
Isolation and genomic analysis of circulating tumor cells from castration resistant metastatic prostate cancer
Magbanua, Mark Jesus M, Sosa, Eduardo V, Scott, Janet H, Simko, Jeff, Collins, Colin, Pinkel, Dan, Ryan, Charles J, Park, John W
Published in BMC cancer (28.02.2012)
Published in BMC cancer (28.02.2012)
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Journal Article
Targeting the Androgen Receptor
Friedlander, Terence W., MD, Ryan, Charles J., MD
Published in Urologic clinics of North America (01.11.2012)
Published in Urologic clinics of North America (01.11.2012)
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