Evolution of a General RNA-Cleaving FANA Enzyme
Wang, Yajun, Ngor, Arlene K., Nikoomanzar, Ali, Chaput, John C.
Published in Nature communications (29.11.2018)
Published in Nature communications (29.11.2018)
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Transliteration of synthetic genetic enzymes
Wang, Yajun, Liu, Xiaolin, Shehabat, Mouhamad, Chim, Nicholas, Chaput, John C
Published in Nucleic acids research (18.11.2021)
Published in Nucleic acids research (18.11.2021)
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Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid
Hajjar, Mohammad, Chim, Nicholas, Liu, Chao, Herdewijn, Piet, Chaput, John C
Published in Nucleic acids research (23.09.2022)
Published in Nucleic acids research (23.09.2022)
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Synthetic Genetic Polymers Capable of Heredity and Evolution
Pinheiro, Vitor B., Taylor, Alexander I., Cozens, Christopher, Abramov, Mikhail, Renders, Marleen, Zhang, Su, Chaput, John C., Wengel, Jesper, Peak-Chew, Sew-Yeu, McLaughlin, Stephen H., Herdewijn, Piet, Holliger, Philipp
Published in Science (American Association for the Advancement of Science) (20.04.2012)
Published in Science (American Association for the Advancement of Science) (20.04.2012)
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Synthesis and Evolution of a Threose Nucleic Acid Aptamer Bearing 7‑Deaza-7-Substituted Guanosine Residues
Mei, Hui, Liao, Jen-Yu, Jimenez, Randi M, Wang, Yajun, Bala, Saikat, McCloskey, Cailen, Switzer, Christopher, Chaput, John C
Published in Journal of the American Chemical Society (02.05.2018)
Published in Journal of the American Chemical Society (02.05.2018)
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A general strategy for expanding polymerase function by droplet microfluidics
Larsen, Andrew C., Dunn, Matthew R., Hatch, Andrew, Sau, Sujay P., Youngbull, Cody, Chaput, John C.
Published in Nature communications (05.04.2016)
Published in Nature communications (05.04.2016)
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The structural diversity of artificial genetic polymers
Anosova, Irina, Kowal, Ewa A, Dunn, Matthew R, Chaput, John C, Van Horn, Wade D, Egli, Martin
Published in Nucleic acids research (18.02.2016)
Published in Nucleic acids research (18.02.2016)
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Following replicative DNA synthesis by time-resolved X-ray crystallography
Chim, Nicholas, Meza, Roman A., Trinh, Anh M., Yang, Kefan, Chaput, John C.
Published in Nature communications (11.05.2021)
Published in Nature communications (11.05.2021)
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An Efficient and Faithful in Vitro Replication System for Threose Nucleic Acid
Yu, Hanyang, Zhang, Su, Dunn, Matthew R, Chaput, John C
Published in Journal of the American Chemical Society (06.03.2013)
Published in Journal of the American Chemical Society (06.03.2013)
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Structural basis for TNA synthesis by an engineered TNA polymerase
Chim, Nicholas, Shi, Changhua, Sau, Sujay P., Nikoomanzar, Ali, Chaput, John C.
Published in Nature communications (27.11.2017)
Published in Nature communications (27.11.2017)
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Creating Protein Affinity Reagents by Combining Peptide Ligands on Synthetic DNA Scaffolds
Williams, Berea A. R, Diehnelt, Chris W, Belcher, Paul, Greving, Matthew, Woodbury, Neal W, Johnston, Stephen A, Chaput, John C
Published in Journal of the American Chemical Society (02.12.2009)
Published in Journal of the American Chemical Society (02.12.2009)
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A biologically stable DNAzyme that efficiently silences gene expression in cells
Wang, Yajun, Nguyen, Kim, Spitale, Robert C., Chaput, John C.
Published in Nature chemistry (01.04.2021)
Published in Nature chemistry (01.04.2021)
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