Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy mouse vessels
Dobnikar, Lina, Taylor, Annabel L., Chappell, Joel, Oldach, Phoebe, Harman, Jennifer L., Oerton, Erin, Dzierzak, Elaine, Bennett, Martin R., Spivakov, Mikhail, Jørgensen, Helle F.
Published in Nature communications (01.11.2018)
Published in Nature communications (01.11.2018)
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Extensive Proliferation of a Subset of Differentiated, yet Plastic, Medial Vascular Smooth Muscle Cells Contributes to Neointimal Formation in Mouse Injury and Atherosclerosis Models
Chappell, Joel, Harman, Jennifer L, Narasimhan, Vagheesh M, Yu, Haixiang, Foote, Kirsty, Simons, Benjamin D, Bennett, Martin R, Jørgensen, Helle F
Published in Circulation research (09.12.2016)
Published in Circulation research (09.12.2016)
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Vascular Smooth Muscle Cell Plasticity and Autophagy in Dissecting Aortic Aneurysms
Clément, Marc, Chappell, Joel, Raffort, Juliette, Lareyre, Fabien, Vandestienne, Marie, Taylor, Annabel L, Finigan, Alison, Harrison, James, Bennett, Martin R, Bruneval, Patrick, Taleb, Soraya, Jørgensen, Helle F, Mallat, Ziad
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.2019)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.2019)
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Dynamic reversal of random X-Chromosome inactivation during iPSC reprogramming
Janiszewski, Adrian, Talon, Irene, Chappell, Joel, Collombet, Samuel, Song, Juan, De Geest, Natalie, To, San Kit, Bervoets, Greet, Marin-Bejar, Oskar, Provenzano, Caterina, Vanheer, Lotte, Marine, Jean-Christophe, Rambow, Florian, Pasque, Vincent
Published in Genome research (01.10.2019)
Published in Genome research (01.10.2019)
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Journal Article
Telomere damage promotes vascular smooth muscle cell senescence and immune cell recruitment after vessel injury
Uryga, Anna K., Grootaert, Mandy O. J., Garrido, Abel M., Oc, Sebnem, Foote, Kirsty, Chappell, Joel, Finigan, Alison, Rossiello, Francesca, d’Adda di Fagagna, Fabrizio, Aravani, Dimitra, Jorgensen, Helle F., Bennett, Martin R.
Published in Communications biology (21.05.2021)
Published in Communications biology (21.05.2021)
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Publisher Correction: Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy mouse vessels
Dobnikar, Lina, Taylor, Annabel L., Chappell, Joel, Oldach, Phoebe, Harman, Jennifer L., Oerton, Erin, Dzierzak, Elaine, Bennett, Martin R., Spivakov, Mikhail, Jørgensen, Helle F.
Published in Nature communications (17.12.2018)
Published in Nature communications (17.12.2018)
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Integrated pseudotime analysis of human pre-implantation embryo single-cell transcriptomes reveals the dynamics of lineage specification
Meistermann, Dimitri, Bruneau, Alexandre, Loubersac, Sophie, Reignier, Arnaud, Firmin, Julie, François-Campion, Valentin, Kilens, Stéphanie, Lelièvre, Yohann, Lammers, Jenna, Feyeux, Magalie, Hulin, Phillipe, Nedellec, Steven, Bretin, Betty, Castel, Gaël, Allègre, Nicolas, Covin, Simon, Bihouée, Audrey, Soumillon, Magali, Mikkelsen, Tarjei, Barrière, Paul, Chazaud, Claire, Chappell, Joel, Pasque, Vincent, Bourdon, Jérémie, Fréour, Thomas, David, Laurent
Published in Cell stem cell (02.09.2021)
Published in Cell stem cell (02.09.2021)
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Interleukin-6 is an activator of pituitary stem cells upon local damage, a competence quenched in the aging gland
Vennekens, Annelies, Laporte, Emma, Hermans, Florian, Cox, Benoit, Modave, Elodie, Janiszewski, Adrian, Nys, Charlotte, Kobayashi, Hiroto, Malengier-Devlies, Bert, Chappell, Joel, Matthys, Patrick, Garcia, Marie-Isabelle, Pasque, Vincent, Lambrechts, Diether, Vankelecom, Hugo
Published in Proceedings of the National Academy of Sciences - PNAS (22.06.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (22.06.2021)
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Organoids from human tooth showing epithelial stemness phenotype and differentiation potential
Hemeryck, Lara, Hermans, Florian, Chappell, Joel, Kobayashi, Hiroto, Lambrechts, Diether, Lambrichts, Ivo, Bronckaers, Annelies, Vankelecom, Hugo
Published in Cellular and molecular life sciences : CMLS (01.03.2022)
Published in Cellular and molecular life sciences : CMLS (01.03.2022)
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Tox4 modulates cell fate reprogramming
Vanheer, Lotte, Song, Juan, De Geest, Natalie, Janiszewski, Adrian, Talon, Irene, Provenzano, Caterina, Oh, Taeho, Chappell, Joel, Pasque, Vincent
Published in Journal of cell science (22.10.2019)
Published in Journal of cell science (22.10.2019)
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Modeling human extraembryonic mesoderm cells using naive pluripotent stem cells
Pham, Thi Xuan Ai, Panda, Amitesh, Kagawa, Harunobu, To, San Kit, Ertekin, Cankat, Georgolopoulos, Grigorios, van Knippenberg, Sam S.F.A., Allsop, Ryan Nicolaas, Bruneau, Alexandre, Chui, Jonathan Sai-Hong, Vanheer, Lotte, Janiszewski, Adrian, Chappell, Joel, Oberhuemer, Michael, Tchinda, Raissa Songwa, Talon, Irene, Khodeer, Sherif, Rossant, Janet, Lluis, Frederic, David, Laurent, Rivron, Nicolas, Balaton, Bradley Philip, Pasque, Vincent
Published in Cell stem cell (01.09.2022)
Published in Cell stem cell (01.09.2022)
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Cellular mechanisms of oligoclonal vascular smooth muscle cell expansion in cardiovascular disease
Worssam, Matt D, Lambert, Jordi, Oc, Sebnem, Taylor, James C K, Taylor, Annabel L, Dobnikar, Lina, Chappell, Joel, Harman, Jennifer L, Figg, Nichola L, Finigan, Alison, Foote, Kirsty, Uryga, Anna K, Bennett, Martin R, Spivakov, Mikhail, Jørgensen, Helle F
Published in Cardiovascular research (22.05.2023)
Published in Cardiovascular research (22.05.2023)
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Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction
Zijlmans, Dick W., Talon, Irene, Verhelst, Sigrid, Bendall, Adam, Van Nerum, Karlien, Javali, Alok, Malcolm, Andrew A., van Knippenberg, Sam S. F. A., Biggins, Laura, To, San Kit, Janiszewski, Adrian, Admiraal, Danielle, Knops, Ruth, Corthout, Nikky, Balaton, Bradley P., Georgolopoulos, Grigorios, Panda, Amitesh, Bhanu, Natarajan V., Collier, Amanda J., Fabian, Charlene, Allsop, Ryan N., Chappell, Joel, Pham, Thi Xuan Ai, Oberhuemer, Michael, Ertekin, Cankat, Vanheer, Lotte, Athanasouli, Paraskevi, Lluis, Frederic, Deforce, Dieter, Jansen, Joop H., Garcia, Benjamin A., Vermeulen, Michiel, Rivron, Nicolas, Dhaenens, Maarten, Marks, Hendrik, Rugg-Gunn, Peter J., Pasque, Vincent
Published in Nature cell biology (01.06.2022)
Published in Nature cell biology (01.06.2022)
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Journal Article
Epigenetic Regulation of Vascular Smooth Muscle Cells by Histone H3 Lysine 9 Dimethylation Attenuates Target Gene-Induction by Inflammatory Signaling
Harman, Jennifer L, Dobnikar, Lina, Chappell, Joel, Stokell, Benjamin G, Dalby, Amanda, Foote, Kirsty, Finigan, Alison, Freire-Pritchett, Paula, Taylor, Annabel L, Worssam, Matthew D, Madsen, Ralitsa R, Loche, Elena, Uryga, Anna, Bennett, Martin R, Jørgensen, Helle F
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2019)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2019)
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Journal Article
BS34 Telomere damage promotes vascular smooth muscle cell senescence and immune cell recruitment after vessel injury
Grootaert, Mandy, Uryga, Anna, Garrido, Abel, Oc, Sebnem, Foote, Kirsty, Chappell, Joel, Finigan, Alison, Rossiello, Francesca, d’Adda di Fagagna, Fabrizio, Aravani, Dimitra, Jorgensen, Helle, Bennett, Martin
Published in Heart (British Cardiac Society) (01.06.2021)
Published in Heart (British Cardiac Society) (01.06.2021)
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Inferring regulators of cell identity in the human adult pancreas
Vanheer, Lotte, Fantuzzi, Federica, To, San Kit, Schiavo, Andrea, Van Haele, Matthias, Ostyn, Tessa, Haesen, Tine, Yi, Xiaoyan, Janiszewski, Adrian, Chappell, Joel, Rihoux, Adrien, Sawatani, Toshiaki, Roskams, Tania, Pattou, Francois, Kerr-Conte, Julie, Cnop, Miriam, Pasque, Vincent
Published in NAR genomics and bioinformatics (01.09.2023)
Published in NAR genomics and bioinformatics (01.09.2023)
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A multi-omics genome-and-transcriptome single-cell atlas of human preimplantation embryogenesis reveals the cellular and molecular impact of chromosome instability
Elia Fernandez Gallardo, Sifrim, Alejandro, Chappell, Joel, Demeulemeester, Jonas, Herrmann, Jennifer Clara, Vermote, Robin, Kerremans, Alison, Michiel Van Der Haegen, Jens Van Herck, Vanuytven, Sebastiaan, Vandereyken, Katy, Macaulay, Iain C, Vermeesch, Joris R, Peeraer, Karen, Debrock, Sophie, Pasque, Vincent, Voet, Thierry
Published in bioRxiv (10.03.2023)
Published in bioRxiv (10.03.2023)
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