H4K20me0 recognition by BRCA1–BARD1 directs homologous recombination to sister chromatids
Nakamura, Kyosuke, Saredi, Giulia, Becker, Jordan R., Foster, Benjamin M., Nguyen, Nhuong V., Beyer, Tracey E., Cesa, Laura C., Faull, Peter A., Lukauskas, Saulius, Frimurer, Thomas, Chapman, J. Ross, Bartke, Till, Groth, Anja
Published in Nature cell biology (01.03.2019)
Published in Nature cell biology (01.03.2019)
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Journal Article
REV7 counteracts DNA double-strand break resection and affects PARP inhibition
Xu, Guotai, Chapman, J. Ross, Brandsma, Inger, Yuan, Jingsong, Mistrik, Martin, Bouwman, Peter, Bartkova, Jirina, Gogola, Ewa, Warmerdam, Daniël, Barazas, Marco, Jaspers, Janneke E., Watanabe, Kenji, Pieterse, Mark, Kersbergen, Ariena, Sol, Wendy, Celie, Patrick H. N., Schouten, Philip C., van den Broek, Bram, Salman, Ahmed, Nieuwland, Marja, de Rink, Iris, de Ronde, Jorma, Jalink, Kees, Boulton, Simon J., Chen, Junjie, van Gent, Dik C., Bartek, Jiri, Jonkers, Jos, Borst, Piet, Rottenberg, Sven
Published in Nature (London) (28.05.2015)
Published in Nature (London) (28.05.2015)
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Journal Article
DNA helicases Sgs1 and BLM promote DNA double-strand break resection
Gravel, Serge, Chapman, J Ross, Magill, Christine, Jackson, Stephen P
Published in Genes & development (15.10.2008)
Published in Genes & development (15.10.2008)
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Journal Article
BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair
Chapman, J Ross, Sossick, Alex J, Boulton, Simon J, Jackson, Stephen P
Published in Journal of cell science (01.08.2012)
Published in Journal of cell science (01.08.2012)
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Journal Article
The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity
Becker, Jordan R., Cuella-Martin, Raquel, Barazas, Marco, Liu, Rui, Oliveira, Catarina, Oliver, Antony W., Bilham, Kirstin, Holt, Abbey B., Blackford, Andrew N., Heierhorst, Jörg, Jonkers, Jos, Rottenberg, Sven, Chapman, J. Ross
Published in Nature communications (17.12.2018)
Published in Nature communications (17.12.2018)
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Journal Article
RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection
Chapman, J. Ross, Barral, Patricia, Vannier, Jean-Baptiste, Borel, Valérie, Steger, Martin, Tomas-Loba, Antonia, Sartori, Alessandro A., Adams, Ian R., Batista, Facundo D., Boulton, Simon J.
Published in Molecular cell (07.03.2013)
Published in Molecular cell (07.03.2013)
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Journal Article
A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis
Altemose, Nicolas, Noor, Nudrat, Bitoun, Emmanuelle, Tumian, Afidalina, Imbeault, Michael, Chapman, J Ross, Aricescu, A Radu, Myers, Simon R
Published in eLife (26.10.2017)
Published in eLife (26.10.2017)
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Journal Article
Regulation of DNA-End Resection by hnRNPU-like Proteins Promotes DNA Double-Strand Break Signaling and Repair
Polo, Sophie E., Blackford, Andrew N., Chapman, J. Ross, Baskcomb, Linda, Gravel, Serge, Rusch, Andre, Thomas, Anoushka, Blundred, Rachel, Smith, Philippa, Kzhyshkowska, Julia, Dobner, Thomas, Taylor, A. Malcolm R., Turnell, Andrew S., Stewart, Grant S., Grand, Roger J., Jackson, Stephen P.
Published in Molecular cell (24.02.2012)
Published in Molecular cell (24.02.2012)
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Journal Article
Orchestration of the DNA-Damage Response by the Rnf8 Ubiquitin Ligase
Kolas, Nadine K., Chapman, J. Ross, Nakada, Shinichiro, Ylanko, Jarkko, Chahwan, Richard, Sweeney, Frédéric D., Panier, Stephanie, Mendez, Megan, Wildenhain, Jan, Thomson, Timothy M., Pelletier, Laurence, Jackson, Stephen P., Durocher, Daniel
Published in Science (American Association for the Advancement of Science) (07.12.2007)
Published in Science (American Association for the Advancement of Science) (07.12.2007)
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Journal Article
Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein
Botuyan, Maria Victoria, Cui, Gaofeng, Drané, Pascal, Oliveira, Catarina, Detappe, Alexandre, Brault, Marie Eve, Parnandi, Nishita, Chaubey, Shweta, Thompson, James R., Bragantini, Benoît, Zhao, Debiao, Chapman, J. Ross, Chowdhury, Dipanjan, Mer, Georges
Published in Nature structural & molecular biology (01.07.2018)
Published in Nature structural & molecular biology (01.07.2018)
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Journal Article
Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining
Francica, Paola, Mutlu, Merve, Blomen, Vincent A., Oliveira, Catarina, Nowicka, Zuzanna, Trenner, Anika, Gerhards, Nora M., Bouwman, Peter, Stickel, Elmer, Hekkelman, Maarten L., Lingg, Lea, Klebic, Ismar, van de Ven, Marieke, de Korte-Grimmerink, Renske, Howald, Denise, Jonkers, Jos, Sartori, Alessandro A., Fendler, Wojciech, Chapman, J. Ross, Brummelkamp, Thijn, Rottenberg, Sven
Published in Cell reports (Cambridge) (25.08.2020)
Published in Cell reports (Cambridge) (25.08.2020)
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Journal Article
53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ
Ghezraoui, Hind, Oliveira, Catarina, Becker, Jordan R., Bilham, Kirstin, Moralli, Daniela, Anzilotti, Consuelo, Fischer, Roman, Deobagkar-Lele, Mukta, Sanchiz-Calvo, Maria, Fueyo-Marcos, Elena, Bonham, Sarah, Kessler, Benedikt M., Rottenberg, Sven, Cornall, Richard J., Green, Catherine M., Chapman, J. Ross
Published in Nature (London) (01.08.2018)
Published in Nature (London) (01.08.2018)
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Journal Article
Mediator of DNA Damage Checkpoint 1 (MDC1) Regulates Mitotic Progression
Townsend, Kelly, Mason, Helen, Blackford, Andrew N., Miller, Edward S., Chapman, J.Ross, Sedgwick, Garry G., Barone, Giancarlo, Turnell, Andrew S., Stewart, Grant S.
Published in The Journal of biological chemistry (04.12.2009)
Published in The Journal of biological chemistry (04.12.2009)
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Journal Article
Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
Hewitt, Graeme, Borel, Valerie, Segura-Bayona, Sandra, Takaki, Tohru, Ruis, Phil, Bellelli, Roberto, Lehmann, Laura C., Sommerova, Lucia, Vancevska, Aleksandra, Tomas-Loba, Antonia, Zhu, Kang, Cooper, Christopher, Fugger, Kasper, Patel, Harshil, Goldstone, Robert, Schneider-Luftman, Deborah, Herbert, Ellie, Stamp, Gordon, Brough, Rachel, Pettitt, Stephen, Lord, Christopher J., West, Stephen C., Ahel, Ivan, Ahel, Dragana, Chapman, J. Ross, Deindl, Sebastian, Boulton, Simon J.
Published in Molecular cell (18.02.2021)
Published in Molecular cell (18.02.2021)
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Journal Article
Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer
Yeow, Zhong Y., Lambrus, Bramwell G., Marlow, Rebecca, Zhan, Kevin H., Durin, Mary-Anne, Evans, Lauren T., Scott, Phillip M., Phan, Thao, Park, Elizabeth, Ruiz, Lorena A., Moralli, Daniela, Knight, Eleanor G., Badder, Luned M., Novo, Daniela, Haider, Syed, Green, Catherine M., Tutt, Andrew N. J., Lord, Christopher J., Chapman, J. Ross, Holland, Andrew J.
Published in Nature (London) (17.09.2020)
Published in Nature (London) (17.09.2020)
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Journal Article