IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis
Zindl, Carlene L., Lai, Jen-Feng, Lee, Yun Kyung, Maynard, Craig L., Harbour, Stacey N., Ouyang, Wenjun, Chaplin, David D., Weaver, Casey T.
Published in Proceedings of the National Academy of Sciences - PNAS (30.07.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (30.07.2013)
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Synthesis and biological evaluation of indole-based, anti-cancer agents inspired by the vascular disrupting agent 2-(3′-hydroxy-4′-methoxyphenyl)-3-(3″,4″,5″-trimethoxybenzoyl)-6-methoxyindole (OXi8006)
MacDonough, Matthew T., Strecker, Tracy E., Hamel, Ernest, Hall, John J., Chaplin, David J., Trawick, Mary Lynn, Pinney, Kevin G.
Published in Bioorganic & medicinal chemistry (01.11.2013)
Published in Bioorganic & medicinal chemistry (01.11.2013)
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Unique Lipid Signatures of Extracellular Vesicles from the Airways of Asthmatics
Hough, Kenneth P, Wilson, Landon S, Trevor, Jennifer L, Strenkowski, John G, Maina, Njeri, Kim, Young-Il, Spell, Marion L, Wang, Yong, Chanda, Diptiman, Dager, Jose Rodriguez, Sharma, Nirmal S, Curtiss, Miranda, Antony, Veena B, Dransfield, Mark T, Chaplin, David D, Steele, Chad, Barnes, Stephen, Duncan, Steven R, Prasain, Jeevan K, Thannickal, Victor J, Deshane, Jessy S
Published in Scientific reports (09.07.2018)
Published in Scientific reports (09.07.2018)
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Neutrophils Produce Interleukin 17A (IL-17A) in a Dectin-1- and IL-23-Dependent Manner during Invasive Fungal Infection
WERNER, Jessica L, GESSNER, Melissa A, BROWN, Gordon D, STEELE, Chad, LILLY, Lauren M, NELSON, Michael P, METZ, Allison E, HORN, Dawn, DUNAWAY, Chad W, DESHANE, Jessy, CHAPLIN, David D, WEAVER, Casey T
Published in Infection and Immunity (01.10.2011)
Published in Infection and Immunity (01.10.2011)
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Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice
Chaplin, David D, Wang, John, Tousson, Albert, Le, Thuc-vy L, Williams, Robert W, Xu, Hui, Yi, John, Wu, Qi, Guentert, Tanja, Myers, Riley, Kolls, Jay K, Yang, PingAr, Carter, Robert H, Stanus, Andrea L, Lorenz, Robin G, Mountz, John D, Chen, Jian, Hsu, Hui-Chen
Published in Nature immunology (01.02.2008)
Published in Nature immunology (01.02.2008)
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Tumor Immune Evasion
Zindl, Carlene L., Chaplin, David D.
Published in Science (American Association for the Advancement of Science) (07.05.2010)
Published in Science (American Association for the Advancement of Science) (07.05.2010)
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Therapy-Induced Acute Recruitment of Circulating Endothelial Progenitor Cells to Tumors
Shaked, Yuval, Ciarrocchi, Alessia, Franco, Marcela, Lee, Christina R, Man, Shan, Cheung, Alison M, Hicklin, Daniel J, Chaplin, David, Foster, F. Stuart, Benezra, Robert, Kerbel, Robert S
Published in Science (American Association for the Advancement of Science) (22.09.2006)
Published in Science (American Association for the Advancement of Science) (22.09.2006)
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Critical role of macrophages and their activation via MyD88-NFκB signaling in lung innate immunity to Mycoplasma pneumoniae
Lai, Jen-Feng, Zindl, Carlene L, Duffy, Lynn B, Atkinson, T Prescott, Jung, Yong Woo, van Rooijen, Nico, Waites, Ken B, Krause, Duncan C, Chaplin, David D
Published in PloS one (23.12.2010)
Published in PloS one (23.12.2010)
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Structure Guided Design, Synthesis, and Biological Evaluation of Novel Benzosuberene Analogues as Inhibitors of Tubulin Polymerization
Niu, Haichan, Strecker, Tracy E, Gerberich, Jeni L, Campbell, James W, Saha, Debabrata, Mondal, Deboprosad, Hamel, Ernest, Chaplin, David J, Mason, Ralph P, Trawick, Mary Lynn, Pinney, Kevin G
Published in Journal of medicinal chemistry (13.06.2019)
Published in Journal of medicinal chemistry (13.06.2019)
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Bioreductively Activatable Prodrug Conjugates of Combretastatin A‑1 and Combretastatin A‑4 as Anticancer Agents Targeted toward Tumor-Associated Hypoxia
Winn, Blake A, Devkota, Laxman, Kuch, Bunnarack, MacDonough, Matthew T, Strecker, Tracy E, Wang, Yifan, Shi, Zhe, Gerberich, Jeni L, Mondal, Deboprosad, Ramirez, Alejandro J, Hamel, Ernest, Chaplin, David J, Davis, Peter, Mason, Ralph P, Trawick, Mary Lynn, Pinney, Kevin G
Published in Journal of natural products (Washington, D.C.) (24.04.2020)
Published in Journal of natural products (Washington, D.C.) (24.04.2020)
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Subsets of airway myeloid-derived regulatory cells distinguish mild asthma from chronic obstructive pulmonary disease
Deshane, Jessy S., PhD, Redden, David T., PhD, Zeng, Meiqin, MS, Spell, Marion L., MS, Zmijewski, Jaroslaw W., PhD, Anderson, John T., MD, Deshane, Rohit J., BS, Gaggar, Amit, MD, PhD, Siegal, Gene P., MD, PhD, Abraham, Edward, MD, Dransfield, Mark T., MD, Chaplin, David D., MD, PhD
Published in Journal of allergy and clinical immunology (01.02.2015)
Published in Journal of allergy and clinical immunology (01.02.2015)
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Design, synthesis, and biological evaluation of water-soluble amino acid prodrug conjugates derived from combretastatin, dihydronaphthalene, and benzosuberene-based parent vascular disrupting agents
Devkota, Laxman, Lin, Chen-Ming, Strecker, Tracy E., Wang, Yifan, Tidmore, Justin K., Chen, Zhi, Guddneppanavar, Rajsekhar, Jelinek, Christopher J., Lopez, Ramona, Liu, Li, Hamel, Ernest, Mason, Ralph P., Chaplin, David J., Trawick, Mary Lynn, Pinney, Kevin G.
Published in Bioorganic & medicinal chemistry (01.03.2016)
Published in Bioorganic & medicinal chemistry (01.03.2016)
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Synthesis of structurally diverse benzosuberene analogues and their biological evaluation as anti-cancer agents
Tanpure, Rajendra P., George, Clinton S., Strecker, Tracy E., Devkota, Laxman, Tidmore, Justin K., Lin, Chen-Ming, Herdman, Christine A., MacDonough, Matthew T., Sriram, Madhavi, Chaplin, David J., Trawick, Mary Lynn, Pinney, Kevin G.
Published in Bioorganic & medicinal chemistry (15.12.2013)
Published in Bioorganic & medicinal chemistry (15.12.2013)
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