Ptpn11/Shp2 Acts as a Tumor Suppressor in Hepatocellular Carcinogenesis
Bard-Chapeau, Emilie A., Li, Shuangwei, Ding, Jin, Zhang, Sharon S., Zhu, Helen H., Princen, Frederic, Fang, Diane D., Han, Tao, Bailly-Maitre, Beatrice, Poli, Valeria, Varki, Nissi M., Wang, Hongyang, Feng, Gen-Sheng
Published in Cancer cell (17.05.2011)
Published in Cancer cell (17.05.2011)
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Initiation of GalNAc-type O-glycosylation in the endoplasmic reticulum promotes cancer cell invasiveness
Gill, David J, Tham, Keit Min, Chia, Joanne, Wang, Shyi Chyi, Steentoft, Catharina, Clausen, Henrik, Bard-Chapeau, Emilie A, Bard, Frederic A
Published in Proceedings of the National Academy of Sciences - PNAS (20.08.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (20.08.2013)
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Dose and Schedule Determine Distinct Molecular Mechanisms Underlying the Efficacy of the p53-MDM2 Inhibitor HDM201
Jeay, Sébastien, Ferretti, Stéphane, Holzer, Philipp, Fuchs, Jeanette, Chapeau, Emilie A, Wartmann, Markus, Sterker, Dario, Romanet, Vincent, Murakami, Masato, Kerr, Grainne, Durand, Eric Y, Gaulis, Swann, Cortes-Cros, Marta, Ruetz, Stephan, Stachyra, Therese-Marie, Kallen, Joerg, Furet, Pascal, Würthner, Jens, Guerreiro, Nelson, Halilovic, Ensar, Jullion, Astrid, Kauffmann, Audrey, Kuriakose, Emil, Wiesmann, Marion, Jensen, Michael R, Hofmann, Francesco, Sellers, William R
Published in Cancer research (Chicago, Ill.) (01.11.2018)
Published in Cancer research (Chicago, Ill.) (01.11.2018)
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Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf−/− mouse model
Chapeau, Emilie A., Gembarska, Agnieszka, Durand, Eric Y., Mandon, Emeline, Estadieu, Claire, Romanet, Vincent, Wiesmann, Marion, Tiedt, Ralph, Lehar, Joseph, deWeck, Antoine, Rad, Roland, Barys, Louise, Jeay, Sebastien, Ferretti, Stephane, Kauffmann, Audrey, Sutter, Esther, Grevot, Armelle, Moulin, Pierre, Murakami, Masato, Sellers, William R., Hofmann, Francesco, Jensen, Michael Rugaard
Published in Proceedings of the National Academy of Sciences - PNAS (21.03.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (21.03.2017)
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Journal Article
Two-Step Forward Genetic Screen in Mice Identifies Ral GTPase-Activating Proteins as Suppressors of Hepatocellular Carcinoma
Kodama, Takahiro, Bard-Chapeau, Emilie A, Newberg, Justin Y, Kodama, Michiko, Rangel, Roberto, Yoshihara, Kosuke, Ward, Jerrold M, Jenkins, Nancy A, Copeland, Neal G
Published in Gastroenterology (New York, N.Y. 1943) (01.08.2016)
Published in Gastroenterology (New York, N.Y. 1943) (01.08.2016)
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A conditional inducible JAK2V617F transgenic mouse model reveals myeloproliferative disease that is reversible upon switching off transgene expression
Chapeau, Emilie A, Mandon, Emeline, Gill, Jason, Romanet, Vincent, Ebel, Nicolas, Powajbo, Violetta, Andraos-Rey, Rita, Qian, Zhiyan, Kininis, Miltos, Zumstein-Mecker, Sabine, Ito, Moriko, Hynes, Nancy E, Tiedt, Ralph, Hofmann, Francesco, Eshkind, Leonid, Bockamp, Ernesto, Kinzel, Bernd, Mueller, Matthias, Murakami, Masato, Baffert, Fabienne, Radimerski, Thomas
Published in PloS one (2019)
Published in PloS one (2019)
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Journal Article
EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation
Bard-Chapeau, Emilie A, Gunaratne, Jayantha, Kumar, Pankaj, Chua, Belinda Q, Muller, Julius, Bard, Frederic A, Blackstock, Walter, Copeland, Neal G, Jenkins, Nancy A
Published in Proceedings of the National Academy of Sciences - PNAS (30.07.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (30.07.2013)
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Journal Article
Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors
Bard-Chapeau, Emilie A., Jeyakani, Justin, Kok, Chung H., Muller, Julius, Chua, Belinda Q., Gunaratne, Jayantha, Batagov, Arsen, Jenjaroenpun, Piroon, Kuznetsov, Vladimir A., Wei, Chia-Lin, D'Andrea, Richard J., Bourque, Guillaume, Jenkins, Nancy A., Copeland, Neal G.
Published in Proceedings of the National Academy of Sciences - PNAS (07.02.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (07.02.2012)
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Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects
Bard-Chapeau, Emilie A, Szumska, Dorota, Jacob, Bindya, Chua, Belinda Q L, Chatterjee, Gouri C, Zhang, Yi, Ward, Jerrold M, Urun, Fatma, Kinameri, Emi, Vincent, Stéphane D, Ahmed, Sayadi, Bhattacharya, Shoumo, Osato, Motomi, Perkins, Archibald S, Moore, Adrian W, Jenkins, Nancy A, Copeland, Neal G
Published in PloS one (27.02.2014)
Published in PloS one (27.02.2014)
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Zip14 expression induced by lipopolysaccharides in macrophages attenuates inflammatory response
Sayadi, Ahmed, Nguyen, Anh-Tuan, Bard, Frederic A., Bard-Chapeau, Emilie A.
Published in Inflammation research (01.02.2013)
Published in Inflammation research (01.02.2013)
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Journal Article
Direct and selective pharmacological disruption of the YAP-TEAD interface by IAG933 inhibits Hippo-dependent and RAS-MAPK-altered cancers
Chapeau, Emilie A, Sansregret, Laurent, Galli, Giorgio G, Chène, Patrick, Wartmann, Markus, Mourikis, Thanos P, Jaaks, Patricia, Baltschukat, Sabrina, Barbosa, Ines A M, Bauer, Daniel, Brachmann, Saskia M, Delaunay, Clara, Estadieu, Claire, Faris, Jason E, Furet, Pascal, Harlfinger, Stefanie, Hueber, Andreas, Jiménez Núñez, Eloísa, Kodack, David P, Mandon, Emeline, Martin, Typhaine, Mesrouze, Yannick, Romanet, Vincent, Scheufler, Clemens, Sellner, Holger, Stamm, Christelle, Sterker, Dario, Tordella, Luca, Hofmann, Francesco, Soldermann, Nicolas, Schmelzle, Tobias
Published in Nature cancer (01.07.2024)
Published in Nature cancer (01.07.2024)
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Author Correction: Direct and selective pharmacological disruption of the YAP-TEAD interface by IAG933 inhibits Hippo-dependent and RAS-MAPK-altered cancers
Chapeau, Emilie A, Sansregret, Laurent, Galli, Giorgio G, Chène, Patrick, Wartmann, Markus, Mourikis, Thanos P, Jaaks, Patricia, Baltschukat, Sabrina, Barbosa, Ines A M, Bauer, Daniel, Brachmann, Saskia M, Delaunay, Clara, Estadieu, Claire, Faris, Jason E, Furet, Pascal, Harlfinger, Stefanie, Hueber, Andreas, Jiménez Núñez, Eloísa, Kodack, David P, Mandon, Emeline, Martin, Typhaine, Mesrouze, Yannick, Romanet, Vincent, Scheufler, Clemens, Sellner, Holger, Stamm, Christelle, Sterker, Dario, Tordella, Luca, Hofmann, Francesco, Soldermann, Nicolas, Schmelzle, Tobias
Published in Nature cancer (01.07.2024)
Published in Nature cancer (01.07.2024)
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Journal Article
Conditional Deletion of Shp2 in the Mammary Gland Leads to Impaired Lobulo-alveolar Outgrowth and Attenuated Stat5 Activation
Ke, Yuehai, Lesperance, Jacqueline, Zhang, Eric E., Bard-Chapeau, Emilie A., Oshima, Robert G., Muller, William J., Feng, Gen-Sheng
Published in The Journal of biological chemistry (10.11.2006)
Published in The Journal of biological chemistry (10.11.2006)
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Journal Article
Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model
Bard-Chapeau, Emilie A, Nguyen, Anh-Tuan, Rust, Alistair G, Sayadi, Ahmed, Lee, Philip, Chua, Belinda Q, New, Lee-Sun, de Jong, Johann, Ward, Jerrold M, Chin, Christopher K Y, Chew, Valerie, Toh, Han Chong, Abastado, Jean-Pierre, Benoukraf, Touati, Soong, Richie, Bard, Frederic A, Dupuy, Adam J, Johnson, Randy L, Radda, George K, Chan, Eric Chun Yong, Wessels, Lodewyk F A, Adams, David J, Jenkins, Nancy A, Copeland, Neal G
Published in Nature genetics (01.01.2014)
Published in Nature genetics (01.01.2014)
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Toll-Like Receptor 3 Expressing Tumor Parenchyma and Infiltrating Natural Killer Cells in Hepatocellular Carcinoma Patients
CHEW, Valerie, TOW, Charlene, NG, Irene Oi-Lin, NARDIN, Alessandra, ABASTADO, Jean-Pierre, HUANG, Caleb, BARD-CHAPEAU, Emilie, COPELAND, Neal G, JENKINS, Nancy A, WEBER, Achim, HON LIM, Kiat, CHONGTOH, Han, HEIKENWALDER, Mathias
Published in JNCI : Journal of the National Cancer Institute (05.12.2012)
Published in JNCI : Journal of the National Cancer Institute (05.12.2012)
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Journal Article
ERK8 is a negative regulator of O-GalNAc glycosylation and cell migration
Chia, Joanne, Tham, Keit Min, Gill, David James, Bard-Chapeau, Emilie Anne, Bard, Frederic A
Published in eLife (11.03.2014)
Published in eLife (11.03.2014)
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