Discovery of a Potent, Non-peptide Bradykinin B1 Receptor Antagonist
Su, Dai-Shi, Markowitz, M. Kristine, DiPardo, Robert M, Murphy, Kathy L, Harrell, C. Meacham, O'Malley, Stacy S, Ransom, Richard W, Chang, Raymond S. L, Ha, Sookhee, Hess, Fred J, Pettibone, Douglas J, Mason, Glenn S, Boyce, Susan, Freidinger, Roger M, Bock, Mark G
Published in Journal of the American Chemical Society (25.06.2003)
Published in Journal of the American Chemical Society (25.06.2003)
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Journal Article
A Family of Highly Selective Allosteric Modulators of the Metabotropic Glutamate Receptor Subtype 5
O'Brien, Julie A., Lemaire, Wei, Chen, Tsing-Bau, Chang, Raymond S. L., Jacobson, Marlene A., Ha, Sookhee N., Lindsley, Craig W., Schaffhauser, Hervé J., Sur, Cyrille, Pettibone, Douglas J., Conn, P. Jeffrey, Williams, David L.
Published in Molecular pharmacology (01.09.2003)
Published in Molecular pharmacology (01.09.2003)
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Journal Article
2-Aminobenzophenones as a Novel Class of Bradykinin B1 Receptor Antagonists
Su, Dai-Shi, Lim, John L, Tinney, Elizabeth, Wan, Bang-Lin, Murphy, Kathy L, Reiss, Duane R, Harrell, C. Meacham, O’Malley, Stacy S, Ransom, Rick W, Chang, Raymond S. L, Pettibone, Douglas J, Yu, Jian, Tang, Cuyue, Prueksaritanont, Thomayant, Freidinger, Roger M, Bock, Mark G, Anthony, Neville J
Published in Journal of medicinal chemistry (10.07.2008)
Published in Journal of medicinal chemistry (10.07.2008)
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Journal Article
Cyclopropylamino Acid Amide as a Pharmacophoric Replacement for 2,3-Diaminopyridine. Application to the Design of Novel Bradykinin B1 Receptor Antagonists
Wood, Michael R, Schirripa, Kathy M, Kim, June J, Wan, Bang-Lin, Murphy, Kathy L, Ransom, Richard W, Chang, Raymond S. L, Tang, Cuyue, Prueksaritanont, Thomayant, Detwiler, Theodore J, Hettrick, Lisa A, Landis, Elizabeth R, Leonard, Yvonne M, Krueger, Julie A, Lewis, Sidney D, Pettibone, Douglas J, Freidinger, Roger M, Bock, Mark G
Published in Journal of medicinal chemistry (23.02.2006)
Published in Journal of medicinal chemistry (23.02.2006)
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Journal Article
2,3-Diaminopyridine Bradykinin B1 Receptor Antagonists
Kuduk, Scott D, Ng, Christina, Feng, Dong-Mei, Wai, Jenny M.-C, Chang, Raymond S. L, Harrell, Charles M, Murphy, Kathy L, Ransom, Richard W, Reiss, Duane, Ivarsson, Magnus, Mason, Glenn, Boyce, Susan, Tang, Cuyue, Prueksaritanont, Thomayant, Freidinger, Roger M, Pettibone, Douglas J, Bock, Mark G
Published in Journal of medicinal chemistry (16.12.2004)
Published in Journal of medicinal chemistry (16.12.2004)
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Journal Article
Design, Synthesis, and In Vivo Efficacy of Glycine Transporter-1 (GlyT1) Inhibitors Derived from a Series of [4-Phenyl-1-(propylsulfonyl)piperidin-4-yl]methyl Benzamides
Lindsley, Craig W., Zhao, Zhijian, Leister, William H., O'Brien, Julie, Lemaire, Wei, Williams Jr, David L., Chen, Tsing-Bau, Chang, Raymond S. L., Burno, Maryann, Jacobson, Marlene A., Sur, Cyrille, Kinney, Gene G., Pettibone, Douglas J., Tiller, Philip R., Smith, Sheri, Tsou, Nancy N., Duggan, Mark E., Conn, P. Jeffrey, Hartman, George D.
Published in ChemMedChem (11.08.2006)
Published in ChemMedChem (11.08.2006)
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Journal Article
Generation and Characterization of a Human Bradykinin Receptor B1 Transgenic Rat as a Pharmacodynamic Model
Hess, J Fred, Ransom, Richard W, Zeng, Zhizhen, Chang, Raymond S L, Hey, Patricia J, Warren, Lee, Harrell, Charles M, Murphy, Kathryn L, Chen, Tsing-Bau, Miller, Patricia J, Lis, Edward, Reiss, Duane, Gibson, Raymond E, Markowitz, M Kristine, DiPardo, Robert M, Su, Dai-Shi, Bock, Mark G, Gould, Robert J, Pettibone, Douglas J
Published in The Journal of pharmacology and experimental therapeutics (01.08.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2004)
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Journal Article
Benzodiazepines as Potent and Selective Bradykinin B1 Antagonists
Wood, Michael R, Kim, June J, Han, Wei, Dorsey, Bruce D, Homnick, Carl F, DiPardo, Robert M, Kuduk, Scott D, MacNeil, Tanya, Murphy, Kathy L, Lis, Edward V, Ransom, Richard W, Stump, Gary L, Lynch, Joseph J, O'Malley, Stacey S, Miller, Patricia J, Chen, Tsing-Bau, Harrell, Charles M, Chang, Raymond S. L, Sandhu, Punam, Ellis, Joan D, Bondiskey, Peter J, Pettibone, Douglas J, Freidinger, Roger M, Bock, Mark G
Published in Journal of medicinal chemistry (08.05.2003)
Published in Journal of medicinal chemistry (08.05.2003)
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Journal Article
In Vitro and in Vivo Evaluation of Dihydropyrimidinone C-5 Amides as Potent and Selective α1A Receptor Antagonists for the Treatment of Benign Prostatic Hyperplasia
Barrow, James C, Nantermet, Philippe G, Selnick, Harold G, Glass, Kristen L, Rittle, Kenneth E, Gilbert, Kevin F, Steele, Thomas G, Homnick, Carl F, Freidinger, Roger M, Ransom, Rick W, Kling, Paul, Reiss, Duane, Broten, Theodore P, Schorn, Terry W, Chang, Raymond S. L, O'Malley, Stacey S, Olah, Timothy V, Ellis, Joan D, Barrish, Andrea, Kassahun, Kelem, Leppert, Paula, Nagarathnam, Dhanapalan, Forray, Carlos
Published in Journal of medicinal chemistry (13.07.2000)
Published in Journal of medicinal chemistry (13.07.2000)
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Journal Article
α-Hydroxy amides as a novel class of bradykinin B1 selective antagonists
WOOD, Michael R, SCHIRRIPA, Kathy M, CHANG, Raymond S. L, HOLAHAN, Marie A, COOK, Jacquelynn J, LEMAIRE, Wei, MOSSER, Scott D, BEDNAR, Rodney A, CUYUE TANG, PRUEKSARITANONT, Thomayant, WALLACE, Audrey A, QIN MEI, KIM, June J, JIAN YU, BOHN, Dennis L, CLAYTON, Frank C, ADARAYN, Emily D, SITKO, Gary R, LEONARD, Yvonne M, FREIDINGER, Roger M, PETTIBONE, Douglas J, BOCK, Mark G, KUDUK, Scott D, CHANG, Ronald K, DI MARCO, Christina N, DIPARDO, Robert M, WAN, Bang-Lin, MURPHY, Kathy L, RANSOM, Richard W
Published in Bioorganic & medicinal chemistry letters (15.01.2008)
Published in Bioorganic & medicinal chemistry letters (15.01.2008)
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Journal Article
2,3-diaminopyridine as a platform for designing structurally unique nonpeptide bradykinin B1 receptor antagonists
FENG, Dong-Mei, WAI, Jenny M, CUYUE TANG, PRUEKSARITANONT, Thomayant, FREIDINGER, Roger M, PETTIBONE, Douglas J, BOCK, Mark G, KUDUK, Scott D, NG, Christina, MURPHY, Kathy L, RANSOM, Richard W, REISS, Duane, CHANG, Raymond S. L, HARRELL, Charles M, MACNEIL, Tanya
Published in Bioorganic & medicinal chemistry letters (02.05.2005)
Published in Bioorganic & medicinal chemistry letters (02.05.2005)
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Journal Article
Non-peptide angiotensin II receptor antagonists. 1. Design, synthesis, and biological activity of N-substituted indoles and dihydroindoles
Dhanoa, Daljit S, Bagley, Scott W, Chang, Raymond S. L, Lotti, Victor J, Chen, Tsing Bau, Kivlighn, Salah D, Zingaro, Gloria J, Siegl, Peter K. S, Patchett, Arthur A, Greenlee, William J
Published in Journal of medicinal chemistry (01.12.1993)
Published in Journal of medicinal chemistry (01.12.1993)
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Journal Article
Design and Synthesis of Novel α1a Adrenoceptor-Selective Dihydropyridine Antagonists for the Treatment of Benign Prostatic Hyperplasia
Nagarathnam, Dhanapalan, Wetzel, John M, Miao, Shou Wu, Marzabadi, Mohammad R, Chiu, George, Wong, Wai C, Hong, Xingfang, Fang, James, Forray, Carlos, Branchek, Theresa A, Heydorn, William E, Chang, Raymond S. L, Broten, Theodore, Schorn, Terry W, Gluchowski, Charles
Published in Journal of medicinal chemistry (17.12.1998)
Published in Journal of medicinal chemistry (17.12.1998)
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Journal Article
Inhibition of acute nociceptive responses in rat spinal cord by a bradykinin B1 receptor antagonist
CONLEY, Rachel K, WHEELDON, Alan, WEBB, Janine K, DIPARDO, Robert M, HOMNICK, Carl F, BOCK, Mark G, CHEN, Tsing-Bau, CHANG, Raymond S. L, PETTIBONE, Douglas J, BOYCE, Susan
Published in European journal of pharmacology (19.12.2005)
Published in European journal of pharmacology (19.12.2005)
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Journal Article
Potent bradykinin B1 receptor antagonists : 4-Substituted phenyl cyclohexanes
SU, Dai-Shi, LIM, John L, PETTIBONE, Douglas J, CUYUE TANG, PRUEKSARITANONT, Thomayant, FREIDINGER, Roger M, BOCK, Mark G, KRISTINE MARKOWITZ, M, WAN, Bang-Lin, MURYHY, Kathy L, REISS, Duane R, MEACHAM HARRELL, C, O'MALLEY, Stacy S, RANSOM, Rick W, CHANG, Raymond S. L
Published in Bioorganic & medicinal chemistry letters (01.06.2007)
Published in Bioorganic & medicinal chemistry letters (01.06.2007)
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Journal Article
(Dipropylphenoxy)phenylacetic acids: a new generation of nonpeptide angiotensin II receptor antagonists
Dhanoa, Daljit S, Bagley, Scott W, Chang, Raymond S. L, Lotti, Victor J, Chen, Tsing Bau, Kivlighn, Salah D, Zingaro, Gloria J, Siegl, Peter K. S, Chakravarty, Prasun K
Published in Journal of medicinal chemistry (01.11.1993)
Published in Journal of medicinal chemistry (01.11.1993)
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Journal Article
Discovery of an Angiotensin II Binding Inhibitor from a Cytospora sp. Using Semi-automated Screening Procedures
STEVENS-MILES, SIOBHAN, GOETZ, MICHAEL A., BILLS, GERALD F., GIACOBBE, ROBERT A., TKACZ, JAN S., CHANG, RAYMOND S. L., MOJENA, MARINA, MARTIN, ISABEL, DIEZ, MARIA TERESA, PELAE, FERNANDO, HENSENS, OTTO D., JONES, TRACY, BURG, RICHARD W., KONG, Y. L., HUANG, LEEYUAN
Published in Journal of antibiotics (1996)
Published in Journal of antibiotics (1996)
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Pharmacological characterization and radioligand binding properties of a high-affinity, nonpeptide, bradykinin B1 receptor antagonist
RANSOM, Richard W, HARRELL, Charles M, SU, Dai-Shi, MARKOWITZ, M. Kristine, WALLACE, Michael A, RAAB, Conrad E, JONES, Allen N, DEAN, Dennis C, PETTIBONE, Douglas J, FREIDINGER, Roger M, BOCK, Mark G, REISS, Duane R, MURPHY, Kathryn L, CHANG, Raymond S. L, HESS, J. Fred, MILLER, Patricia J, O'MALLEY, Stacey S, HEY, Pat J, KUNAPULI, Priya
Published in European journal of pharmacology (19.09.2004)
Published in European journal of pharmacology (19.09.2004)
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Journal Article
A potent, orally active, balanced affinity angiotensin II AT1 antagonist and AT2 binding inhibitor
de Laszlo, Stephen E, Quagliato, Carol S, Greenlee, William J, Patchett, Arthur A, Chang, Raymond S. L, Lotti, Victor J, Chen, Tsing Bau, Scheck, Stacey A, Faust, Kristi A
Published in Journal of medicinal chemistry (01.10.1993)
Published in Journal of medicinal chemistry (01.10.1993)
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Difference in mGluR5 Interaction between Positive Allosteric Modulators from Two Structural Classes
WILLIAMS JR, DAVID L., O'BRIEN, JULIE A., LEMAIRE, WEI, CHEN, TSING-BAU, CHANG, RAYMOND S. L., JACOBSON, MARLENE A., HA, SOOKHEE N., WISNOSKI, DAVID D., LINDSLEY, CRAIG W., SUR, CYRILLE, DUGGAN, MARK E., PETTIBONE, DOUGLAS J., CONN, P. JEFFREY
Published in Annals of the New York Academy of Sciences (01.11.2003)
Published in Annals of the New York Academy of Sciences (01.11.2003)
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