Mechanisms of protein stabilization in the solid state
Chang, Liuquan (Lucy), Pikal, Michael J.
Published in Journal of pharmaceutical sciences (01.09.2009)
Published in Journal of pharmaceutical sciences (01.09.2009)
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Journal Article
Mechanism of protein stabilization by sugars during freeze-drying and storage: Native structure preservation, specific interaction, and/or immobilization in a glassy matrix?
Chang, Liuquan (Lucy), Shepherd, Deanna, Sun, Joanna, Ouellette, David, Grant, Kathleen L., Tang, Xiaolin (Charlie), Pikal, Michael J.
Published in Journal of pharmaceutical sciences (01.07.2005)
Published in Journal of pharmaceutical sciences (01.07.2005)
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Journal Article
Effect of sorbitol and residual moisture on the stability of lyophilized antibodies: Implications for the mechanism of protein stabilization in the solid state
Chang, Liuquan (Lucy), Shepherd, Deanna, Sun, Joanna, Tang, Xiaolin (Charlie), Pikal, Michael J.
Published in Journal of pharmaceutical sciences (01.07.2005)
Published in Journal of pharmaceutical sciences (01.07.2005)
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Journal Article
Nonnative Aggregation of an IgG1 Antibody in Acidic Conditions: Part 1. Unfolding, Colloidal Interactions, and Formation of High-Molecular-Weight Aggregates
Brummitt, Rebecca K., Nesta, Douglas P., Chang, Liuquan, Chase, Susan F., Laue, Thomas M., Roberts, Christopher J.
Published in Journal of pharmaceutical sciences (01.06.2011)
Published in Journal of pharmaceutical sciences (01.06.2011)
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Journal Article
Nonnative Aggregation of an IgG1 Antibody in Acidic Conditions, Part 2: Nucleation and Growth Kinetics with Competing Growth Mechanisms
Brummitt, Rebecca K., Nesta, Douglas P., Chang, Liuquan, Kroetsch, Andrew M., Roberts, Christopher J.
Published in Journal of pharmaceutical sciences (01.06.2011)
Published in Journal of pharmaceutical sciences (01.06.2011)
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Journal Article
The Glass Transition and Sub-Tg-Relaxation in Pharmaceutical Powders and Dried Proteins by Thermally Stimulated Current
Reddy, Renuka, Chang, Liuquan (Lucy), Luthra, Suman, Collins, George, Lopez, Ciro, Shamblin, Sheri L., Pikal, Michael J., Gatlin, Larry A., Shalaev, Evgenyi Y.
Published in Journal of pharmaceutical sciences (01.01.2009)
Published in Journal of pharmaceutical sciences (01.01.2009)
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Journal Article
Evaluation of glassy-state dynamics from the width of the glass transition: Results from theoretical simulation of differential scanning calorimetry and comparisons with experiment
Pikal, Michael J., Chang, Liuquan (Lucy), Tang, Xiaolin (Charlie)
Published in Journal of pharmaceutical sciences (01.04.2004)
Published in Journal of pharmaceutical sciences (01.04.2004)
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Journal Article
Using modulated DSC to investigate the origin of multiple thermal transitions in frozen 10% sucrose solutions
Chang, Liuquan (Lucy), Milton, Nathaniel, Rigsbee, Daniel, Mishra, Dinesh S., Tang, Xiaolin (Charlie), Thomas, Leonard C., Pikal, Michael J.
Published in Thermochimica acta (15.05.2006)
Published in Thermochimica acta (15.05.2006)
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Journal Article
The glass transition and sub-T(g)-relaxation in pharmaceutical powders and dried proteins by thermally stimulated current
Reddy, Renuka, Chang, Liuquan ' Lucy ', Luthra, Suman, Collins, George, Lopez, Ciro, Shamblin, Sheri L, Pikal, Michael J, Gatlin, Larry A, Shalaev, Evgenyi Y
Published in Journal of pharmaceutical sciences (01.01.2009)
Published in Journal of pharmaceutical sciences (01.01.2009)
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Journal Article