Geranylgeranyl pyrophosphate amplifies Treg differentiation via increased IL‐2 expression to ameliorate DSS‐induced colitis
Pandit, Mahesh, Acharya, Suman, Gu, Ye, Seo, Sang‐Uk, Kweon, Mi‐Na, Kang, Ben, Chang, Jae‐Hoon
Published in European journal of immunology (01.06.2021)
Published in European journal of immunology (01.06.2021)
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AMPK promotes antitumor immunity by downregulating PD-1 in regulatory T cells via the HMGCR/p38 signaling pathway
Pokhrel, Ram Hari, Acharya, Suman, Ahn, Jae-Hee, Gu, Ye, Pandit, Mahesh, Kim, Jong-Oh, Park, Yun-Yong, Kang, Ben, Ko, Hyun-Jeong, Chang, Jae-Hoon
Published in Molecular cancer (14.10.2021)
Published in Molecular cancer (14.10.2021)
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The orphan nuclear receptor NR4A1 promotes FcεRI‐stimulated mast cell activation and anaphylaxis by counteracting the inhibitory LKB1/AMPK axis
Jin, Fansi, Li, Xian, Deng, Yifeng, Timilshina, Maheshwor, Huang, Bin, Kim, Dong‐Young, Chang, Jae‐Hoon, Ichinose, Hiroshi, Baek, Suk‐Hwan, Murakami, Makoto, Lee, Youn Ju, Chang, Hyeun Wook
Published in Allergy (Copenhagen) (01.06.2019)
Published in Allergy (Copenhagen) (01.06.2019)
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Methionine consumption by cancer cells drives a progressive upregulation of PD-1 expression in CD4 T cells
Pandit, Mahesh, Kil, Yun-Seo, Ahn, Jae-Hee, Pokhrel, Ram Hari, Gu, Ye, Mishra, Sunil, Han, Youngjoo, Ouh, Yung-Taek, Kang, Ben, Jeong, Myeong Seon, Kim, Jong-Oh, Nam, Joo-Won, Ko, Hyun-Jeong, Chang, Jae-Hoon
Published in Nature communications (05.05.2023)
Published in Nature communications (05.05.2023)
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A common signaling pathway leading to degranulation in mast cells and its regulation by CCR1‐ligand
Chang, Hyeun Wook, Kanegasaki, Shiro, Jin, Fansi, Deng, Yifeng, You, Zhiwei, Chang, Jae‐Hoon, Kim, Dong Young, Timilshina, Maheshwor, Kim, Jae‐Ryong, Lee, Youn Ju, Toyama‐Sorimachi, Noriko, Tsuchiya, Tomoko
Published in Allergy (Copenhagen) (01.06.2020)
Published in Allergy (Copenhagen) (01.06.2020)
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AMPK suppresses Th2 cell responses by repressing mTORC2
Pandit, Mahesh, Timilshina, Maheshwor, Gu, Ye, Acharya, Suman, Chung, Yeonseok, Seo, Sang-Uk, Chang, Jae-Hoon
Published in Experimental & molecular medicine (01.08.2022)
Published in Experimental & molecular medicine (01.08.2022)
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Combination chemotherapeutic and immune-therapeutic anticancer approach via anti-PD-L1 antibody conjugated albumin nanoparticles
Pham, Le Minh, Poudel, Kishwor, Ou, Wenquan, Phung, Cao Dai, Nguyen, Hanh Thuy, Nguyen, Bao Loc, Karmacharya, Prajeena, Pandit, Mahesh, Chang, Jae-Hoon, Jeong, Jee-Heon, Ku, Sae Kwang, Yong, Chul Soon, Choi, Han-Gon, Kim, Jong Oh
Published in International journal of pharmaceutics (10.08.2021)
Published in International journal of pharmaceutics (10.08.2021)
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Downregulation of Th17 cells in the small intestine by disruption of gut flora in the absence of retinoic acid
Cha, Hye-Ran, Chang, Sun-Young, Chang, Jae-Hoon, Kim, Jae-Ouk, Yang, Jin-Young, Kim, Chang-Hoon, Kweon, Mi-Na
Published in The Journal of immunology (1950) (15.06.2010)
Published in The Journal of immunology (1950) (15.06.2010)
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Globular Adiponectin Inhibits Breast Cancer Cell Growth through Modulation of Inflammasome Activation: Critical Role of Sestrin2 and AMPK Signaling
Pham, Duc-Vinh, Raut, Pawan Kumar, Pandit, Mahesh, Chang, Jae-Hoon, Katila, Nikita, Choi, Dong-Young, Jeong, Jee-Heon, Park, Pil-Hoon
Published in Cancers (06.03.2020)
Published in Cancers (06.03.2020)
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Reactive oxygen species‐responsive dual‐targeted nanosystem promoted immunogenic cell death against breast cancer
Banstola, Asmita, Pandit, Mahesh, Duwa, Ramesh, Chang, Jae‐Hoon, Jeong, Jee‐Heon, Yook, Simmyung
Published in Bioengineering & translational medicine (01.09.2023)
Published in Bioengineering & translational medicine (01.09.2023)
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Globular Adiponectin Inhibits Lipopolysaccharide-Primed Inflammasomes Activation in Macrophages via Autophagy Induction: The Critical Role of AMPK Signaling
Kim, Mi Jin, Kim, Eun Hye, Pun, Nirmala TiliJa, Chang, Jae-Hoon, Kim, Jung-Ae, Jeong, Jee-Heon, Choi, Dong Young, Kim, Sang-Hyun, Park, Pil-Hoon
Published in International journal of molecular sciences (15.06.2017)
Published in International journal of molecular sciences (15.06.2017)
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Shaping the “hot” immunogenic tumor microenvironment by nanoparticles co‐delivering oncolytic peptide and TGF ‐β1 siRNA for boosting checkpoint blockade therapy
Phung, Cao Dai, Nguyen, Bao Loc, Jeong, Jee‐Heon, Chang, Jae‐Hoon, Jin, Sung Giu, Choi, Han‐Gon, Ku, Sae Kwang, Kim, Jong Oh
Published in Bioengineering & translational medicine (01.09.2023)
Published in Bioengineering & translational medicine (01.09.2023)
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Journal Article
AMPK Alchemy: Therapeutic Potentials in Allergy, Aging, and Cancer
Pokhrel, Ram Hari, Acharya, Suman, Mishra, Sunil, Gu, Ye, Manzoor, Umar, Kim, Jeon-Kyung, Park, Youngjun, Chang, Jae-Hoon
Published in Biomolecules & therapeutics (01.03.2024)
Published in Biomolecules & therapeutics (01.03.2024)
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BJ-3105, a 6-Alkoxypyridin-3-ol Analog, Impairs T Cell Differentiation and Prevents Experimental Autoimmune Encephalomyelitis Disease Progression
Timilshina, Maheshwor, Kang, Youra, Dahal, Ishmit, You, Zhiwei, Nam, Tae-Gyu, Kim, Keuk-Jun, Jeong, Byeong-Seon, Chang, Jae-Hoon
Published in PloS one (01.01.2017)
Published in PloS one (01.01.2017)
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Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK- and PTP1B-dependent processes
Li, Xian, Lee, Youn Ju, Jin, Fansi, Park, Young Na, Deng, Yifeng, Kang, Youra, Yang, Ju Hye, Chang, Jae-Hoon, Kim, Dong-Young, Kim, Jung-Ae, Chang, Young-Chae, Ko, Hyun-Jeong, Kim, Cheorl-Ho, Murakami, Makoto, Chang, Hyeun Wook
Published in Scientific reports (25.07.2017)
Published in Scientific reports (25.07.2017)
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