Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma
Natsuizaka, Mitsuteru, Whelan, Kelly A, Kagawa, Shingo, Tanaka, Koji, Giroux, Veronique, Chandramouleeswaran, Prasanna M, Long, Apple, Sahu, Varun, Darling, Douglas S, Que, Jianwen, Yang, Yizeng, Katz, Jonathan P, Wileyto, E Paul, Basu, Devraj, Kita, Yoshiaki, Natsugoe, Shoji, Naganuma, Seiji, Klein-Szanto, Andres J, Diehl, J Alan, Bass, Adam J, Wong, Kwok-Kin, Rustgi, Anil K, Nakagawa, Hiroshi
Published in Nature communications (24.11.2017)
Published in Nature communications (24.11.2017)
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Journal Article
Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes
Chandramouleeswaran, Prasanna M, Guha, Manti, Shimonosono, Masataka, Whelan, Kelly A, Maekawa, Hisatsugu, Sachdeva, Uma M, Ruthel, Gordon, Mukherjee, Sarmistha, Engel, Noah, Gonzalez, Michael V, Garifallou, James, Ohashi, Shinya, Klein-Szanto, Andres J, Mesaros, Clementina A, Blair, Ian A, Pellegrino da Silva, Renata, Hakonarson, Hakon, Noguchi, Eishi, Baur, Joseph A, Nakagawa, Hiroshi
Published in PloS one (23.09.2020)
Published in PloS one (23.09.2020)
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Journal Article
Preferential Secretion of Thymic Stromal Lymphopoietin (TSLP) by Terminally Differentiated Esophageal Epithelial Cells: Relevance to Eosinophilic Esophagitis (EoE)
Chandramouleeswaran, Prasanna M, Shen, Dawen, Lee, Anna J, Benitez, Alain, Dods, Kara, Gambanga, Fiona, Wilkins, Benjamin J, Merves, Jamie, Noah, Yuliana, Toltzis, Sarit, Yearley, Jennifer H, Spergel, Jonathan M, Nakagawa, Hiroshi, Malefyt, Rene deWaal, Muir, Amanda B, Wang, Mei-Lun
Published in PloS one (18.03.2016)
Published in PloS one (18.03.2016)
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Journal Article
Fibrostenotic eosinophilic esophagitis might reflect epithelial lysyl oxidase induction by fibroblast-derived TNF-α
Kasagi, Yuta, Dods, Kara, Wang, Joshua X., Chandramouleeswaran, Prasanna M., Benitez, Alain J., Gambanga, Fiona, Kluger, Jonathan, Ashorobi, Tokunbo, Gross, Jonathan, Tobias, John W., Klein-Szanto, Andres J., Spergel, Jonathan M., Cianferoni, Antonella, Falk, Gary W., Whelan, Kelly A., Nakagawa, Hiroshi, Muir, Amanda B.
Published in Journal of allergy and clinical immunology (01.07.2019)
Published in Journal of allergy and clinical immunology (01.07.2019)
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Journal Article
Autophagy mediates epithelial cytoprotection in eosinophilic oesophagitis
Whelan, Kelly A, Merves, Jamie F, Giroux, Veronique, Tanaka, Koji, Guo, Andy, Chandramouleeswaran, Prasanna M, Benitez, Alain J, Dods, Kara, Que, Jianwen, Masterson, Joanne C, Fernando, Shahan D, Godwin, Bridget C, Klein-Szanto, Andres J, Chikwava, Kudakwashe, Ruchelli, Eduardo D, Hamilton, Kathryn E, Muir, Amanda B, Wang, Mei-Lun, Furuta, Glenn T, Falk, Gary W, Spergel, Jonathan M, Nakagawa, Hiroshi
Published in Gut (01.07.2017)
Published in Gut (01.07.2017)
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Journal Article
Esophageal epithelial and mesenchymal cross-talk leads to features of epithelial to mesenchymal transition in vitro
Muir, Amanda B., Lim, Diana M., Benitez, Alain J., Modayur Chandramouleeswaran, Prasanna, Lee, Anna J., Ruchelli, Eduardo D., Spergel, Jonathan M., Wang, Mei-Lun
Published in Experimental cell research (01.04.2013)
Published in Experimental cell research (01.04.2013)
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Journal Article
Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells
Kijima, Takashi, Nakagawa, Hiroshi, Shimonosono, Masataka, Chandramouleeswaran, Prasanna M, Hara, Takeo, Sahu, Varun, Kasagi, Yuta, Kikuchi, Osamu, Tanaka, Koji, Giroux, Veronique, Muir, Amanda B, Whelan, Kelly A, Ohashi, Shinya, Naganuma, Seiji, Klein-Szanto, Andres J, Shinden, Yoshiaki, Sasaki, Ken, Omoto, Itaru, Kita, Yoshiaki, Muto, Manabu, Bass, Adam J, Diehl, J. Alan, Ginsberg, Gregory G, Doki, Yuichiro, Mori, Masaki, Uchikado, Yasuto, Arigami, Takaaki, Avadhani, Narayan G, Basu, Devraj, Rustgi, Anil K, Natsugoe, Shoji
Published in Cellular and molecular gastroenterology and hepatology (01.01.2019)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2019)
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Journal Article
The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial Changes
Kasagi, Yuta, Chandramouleeswaran, Prasanna M, Whelan, Kelly A, Tanaka, Koji, Giroux, Veronique, Sharma, Medha, Wang, Joshua, Benitez, Alain J, DeMarshall, Maureen, Tobias, John W, Hamilton, Kathryn E, Falk, Gary W, Spergel, Jonathan M, Klein-Szanto, Andres J, Rustgi, Anil K, Muir, Amanda B, Nakagawa, Hiroshi
Published in Cellular and molecular gastroenterology and hepatology (01.01.2018)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2018)
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Journal Article
Esophageal 3D organoids of MPV17 -/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition
Guha, Manti, Srinivasan, Satish, Sheehan, Maura M, Kijima, Takashi, Ruthel, Gordon, Whelan, Kelly, Tanaka, Koji, Klein-Szanto, Andres, Chandramouleeswaran, Prasanna M, Nakagawa, Hiroshi, Avadhani, Narayan G
Published in Oncotarget (22.10.2019)
Published in Oncotarget (22.10.2019)
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Journal Article
Altered esophageal histamine receptor expression in Eosinophilic Esophagitis (EoE): implications on disease pathogenesis
Merves, Jamie, Chandramouleeswaran, Prasanna Modayur, Benitez, Alain J, Muir, Amanda B, Lee, Anna J, Lim, Diana M, Dods, Kara, Mehta, Isha, Ruchelli, Eduardo D, Nakagawa, Hiroshi, Spergel, Jonathan M, Wang, Mei-Lun
Published in PloS one (27.02.2015)
Published in PloS one (27.02.2015)
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Journal Article
Food allergen triggers are increased in children with the TSLP risk allele and eosinophilic esophagitis
Fahey, Lisa M, Chandramouleeswaran, Prasanna M, Guan, Shaobo, Benitez, Alain J, Furuta, Glenn T, Aceves, Seema S, Wang, Mei-Lun, Liacouras, Chris A, Muir, Amanda B, Sleiman, Patrick Ma, Hakonarson, Hakon, Spergel, Jonathan M, Cianferoni, Antonella
Published in Clinical and translational gastroenterology (06.03.2018)
Published in Clinical and translational gastroenterology (06.03.2018)
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Journal Article
411 Preferential Expression and Food Antigen-Mediated Induction of Thymic Stromal Lymphopoietin in Differentiated Esophageal Epithelial Cells in Eosinophilic Esophagitis
Chandramouleeswaran, Prasanna M, Lee, Anna J, Noah, Yuliana, Benitez, Alain J, Tait-Wojno, Elia, Muir, Amanda, Shen, Dawen, Toltzis, Sarit, Artis, David, De Waal Malefyt, Rene, Wang, Mei-Lun
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
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Journal Article
ALDH2 modulates autophagy flux to regulate acetaldehyde-mediated toxicity thresholds
Tanaka, Koji, Whelan, Kelly A, Chandramouleeswaran, Prasanna M, Kagawa, Shingo, Rustgi, Sabrina L, Noguchi, Chiaki, Guha, Manti, Srinivasan, Satish, Amanuma, Yusuke, Ohashi, Shinya, Muto, Manabu, Klein-Szanto, Andres J, Noguchi, Eishi, Avadhani, Narayan G, Nakagawa, Hiroshi
Published in American journal of cancer research (01.01.2016)
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Published in American journal of cancer research (01.01.2016)
Journal Article
Esophageal epithelial cells acquire functional characteristics of activated myofibroblasts after undergoing an epithelial to mesenchymal transition
Muir, Amanda B., Dods, Kara, Noah, Yuli, Toltzis, Sarit, Chandramouleeswaran, Prasanna Modayur, Lee, Anna, Benitez, Alain, Bedenbaugh, Adam, Falk, Gary W., Wells, Rebecca G., Nakagawa, Hiroshi, Wang, Mei-Lun
Published in Experimental cell research (01.01.2015)
Published in Experimental cell research (01.01.2015)
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Journal Article
Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance
Whelan, K A, Chandramouleeswaran, P M, Tanaka, K, Natsuizaka, M, Guha, M, Srinivasan, S, Darling, D S, Kita, Y, Natsugoe, S, Winkler, J D, Klein-Szanto, A J, Amaravadi, R K, Avadhani, N G, Rustgi, A K, Nakagawa, H
Published in Oncogene (24.08.2017)
Published in Oncogene (24.08.2017)
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Journal Article
The role of Ndfip1 in macrophage-mediated bacterial clearance
Field, Natania S, Moser, Emily K, Chandramouleeswaran, Prasanna, Subudhi, Ipsita, Vasquez, Nikoff, Oliver, Paula M
Published in The Journal of immunology (1950) (01.05.2017)
Published in The Journal of immunology (1950) (01.05.2017)
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Journal Article
Abstract 6613: Label-free multimodal multiphoton microscopy for predicting DNA damage response in patient derived non-small cell lung cancer organoids
Roh, Terrence T., Alex, Aneesh, Sorrells, Janet E., Chandramouleeswaran, Prasanna, Marjanovic, Marina, Hood, Steve R., Sridharan, BanuPriya, Boppart, Stephen A.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
463 - Rapamycin-Mediated Autophagy Activation Ameliorates Eoeassociated Alterations in Epithelial Tissue Architecture
Whelan, Kelly A., Chandramouleeswaran, Prasanna, Sharma, Medha, Benitez, Alain, DeMarshall, Maureen, Klein-Szanto, Andres, Spergel, Jonathan, Falk, Gary W., Muir, Amanda B., Nakagawa, Hiroshi
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2018)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2018)
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