Stabilization of interdomain interactions in G protein α subunits as a determinant of Gαi subtype signaling specificity
Lefevre, Tyler J., Wei, Wenyuan, Mukhaleva, Elizaveta, Meda Venkata, Sai Pranathi, Chandan, Naincy R., Abraham, Saji, Li, Yong, Dessauer, Carmen W., Vaidehi, Nagarajan, Smrcka, Alan V.
Published in The Journal of biological chemistry (01.05.2024)
Published in The Journal of biological chemistry (01.05.2024)
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Journal Article
Identifying Novel Signaling Mechanisms Downstream of G q -Coupled Receptors
Loomis, Joseph F, Chandan, Naincy R, Brody, Matthew J, Smrcka, Alan V
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
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Discovery of Small Molecules That Target the Phosphatidylinositol (3,4,5) Trisphosphate (PIP3)-Dependent Rac Exchanger 1 (P-Rex1) PIP3-Binding Site and Inhibit P-Rex1–Dependent Functions in Neutrophils
Cash, Jennifer N., Chandan, Naincy R., Hsu, Alan Y., Sharma, Prateek V., Deng, Qing, Smrcka, Alan V., Tesmer, John J.G.
Published in Molecular pharmacology (01.03.2020)
Published in Molecular pharmacology (01.03.2020)
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Journal Article
Discovery of Small Molecules That Target the Phosphatidylinositol (3,4,5) Trisphosphate (PIP 3 )-Dependent Rac Exchanger 1 (P-Rex1) PIP 3 -Binding Site and Inhibit P-Rex1-Dependent Functions in Neutrophils
Cash, Jennifer N, Chandan, Naincy R, Hsu, Alan Y, Sharma, Prateek V, Deng, Qing, Smrcka, Alan V, Tesmer, John J G
Published in Molecular pharmacology (01.03.2020)
Published in Molecular pharmacology (01.03.2020)
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Journal Article
Stabilization of Interdomain Interactions in G protein α i Subunits Determines Gα i Subtype Signaling Specificity
Lefevre, Tyler J, Wei, Wenyuan, Mukhaleva, Elizaveta, Venkata, Sai Pranathi Meda, Chandan, Naincy R, Abraham, Saji, Li, Yong, Dessauer, Carmen W, Vaidehi, Nagarajan, Smrcka, Alan V
Published in bioRxiv : the preprint server for biology (06.04.2023)
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Published in bioRxiv : the preprint server for biology (06.04.2023)
Journal Article
An Ionic Lock Mediates Interdomain Interactions in G protein αi subunits and Determines Gαi Subtype Signaling Specificity
Lefevre, Tyler, Wei, Wenyuan, Mukhaleva, Elizaveta, Sai Pranathi Meda Venkata, Chandan, Naincy R, Abraham, Saji, Nagarajan Vaidehi, Smrcka, Alan
Published in bioRxiv (12.03.2023)
Published in bioRxiv (12.03.2023)
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