Complex Interplay between Epitope Specificity and Isotype Dictates the Biological Activity of Anti-human CD40 Antibodies
Yu, Xiaojie, Chan, H.T. Claude, Orr, Christian M., Dadas, Osman, Booth, Steven G., Dahal, Lekh N., Penfold, Christine A., O'Brien, Lyn, Mockridge, C. Ian, French, Ruth R., Duriez, Patrick, Douglas, Leon R., Pearson, Arwen R., Cragg, Mark S., Tews, Ivo, Glennie, Martin J., White, Ann L.
Published in Cancer cell (09.04.2018)
Published in Cancer cell (09.04.2018)
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Mass spectrometric assays monitoring the deubiquitinase activity of the SARS-CoV-2 papain-like protease inform on the basis of substrate selectivity and have utility for substrate identification
Brewitz, Lennart, Henry Chan, H T, Lukacik, Petra, Strain-Damerell, Claire, Walsh, Martin A, Duarte, Fernanda, Schofield, Christopher J
Published in Bioorganic & medicinal chemistry (15.11.2023)
Published in Bioorganic & medicinal chemistry (15.11.2023)
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Analysis of β-lactone formation by clinically observed carbapenemases informs on a novel antibiotic resistance mechanism
Aertker, Kristina M.J., Chan, H.T. Henry, Lohans, Christopher T., Schofield, Christopher J.
Published in The Journal of biological chemistry (04.12.2020)
Published in The Journal of biological chemistry (04.12.2020)
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Journal Article
Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment
Turaj, Anna H., Hussain, Khiyam, Cox, Kerry L., Rose-Zerilli, Matthew J.J., Testa, James, Dahal, Lekh N., Chan, H.T. Claude, James, Sonya, Field, Vikki L., Carter, Matthew J., Kim, Hyung J., West, Jonathan J., Thomas, Lawrence J., He, Li-Zhen, Keler, Tibor, Johnson, Peter W.M., Al-Shamkhani, Aymen, Thirdborough, Stephen M., Beers, Stephen A., Cragg, Mark S., Glennie, Martin J., Lim, Sean H.
Published in Cancer cell (11.12.2017)
Published in Cancer cell (11.12.2017)
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Antagonistic Human FcγRIIB (CD32B) Antibodies Have Anti-Tumor Activity and Overcome Resistance to Antibody Therapy In Vivo
Roghanian, Ali, Teige, Ingrid, Mårtensson, Linda, Cox, Kerry L., Kovacek, Mathilda, Ljungars, Anne, Mattson, Jenny, Sundberg, Annika, Vaughan, Andrew T., Shah, Vallari, Smyth, Neil R., Sheth, Bhavwanti, Chan, H.T. Claude, Li, Zhan-Chun, Williams, Emily L., Manfredi, Giusi, Oldham, Robert J., Mockridge, C. Ian, James, Sonya A., Dahal, Lekh N., Hussain, Khiyam, Nilsson, Björn, Verbeek, J. Sjef, Juliusson, Gunnar, Hansson, Markus, Jerkeman, Mats, Johnson, Peter W.M., Davies, Andrew, Beers, Stephen A., Glennie, Martin J., Frendéus, Björn, Cragg, Mark S.
Published in Cancer cell (13.04.2015)
Published in Cancer cell (13.04.2015)
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Antigenic modulation limits the efficacy of anti-CD20 antibodies: implications for antibody selection
Beers, Stephen A., French, Ruth R., Chan, H.T. Claude, Lim, Sean H., Jarrett, Timothy C., Vidal, Regina Mora, Wijayaweera, Sahan S., Dixon, Sandra V., Kim, Hyungjin, Cox, Kerry L., Kerr, Jonathan P., Johnston, David A., Johnson, Peter W.M., Verbeek, J. Sjef, Glennie, Martin J., Cragg, Mark S.
Published in Blood (24.06.2010)
Published in Blood (24.06.2010)
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FcγRIIB controls antibody-mediated target cell depletion by ITIM-independent mechanisms
Simpson, Alexander P., Roghanian, Ali, Oldham, Robert J., Chan, H.T. Claude, Penfold, Christine A., Kim, Hyung J., Inzhelevskaya, Tatyana, Mockridge, C. Ian, Cox, Kerry L., Bogdanov, Yury D., James, Sonya, Tutt, Alison L., Rycroft, Daniel, Morley, Peter, Dahal, Lekh N., Teige, Ingrid, Frendeus, Björn, Beers, Stephen A., Cragg, Mark S.
Published in Cell reports (Cambridge) (19.07.2022)
Published in Cell reports (Cambridge) (19.07.2022)
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Natto and miso: an overview on their preparation, bioactive components and health-promoting effects
Chan, E.W.C., Wong, S.K., Kezuka, M., Oshiro, N., Chan, H.T.
Published in Food Research (Online) (30.06.2021)
Published in Food Research (Online) (30.06.2021)
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Shaving Is an Epiphenomenon of Type I and II Anti-CD20-Mediated Phagocytosis, whereas Antigenic Modulation Limits Type I Monoclonal Antibody Efficacy
Dahal, Lekh N, Huang, Chie-Yin, Stopforth, Richard J, Mead, Abbie, Chan, Keith, Bowater, Juliet X, Taylor, Martin C, Narang, Priyanka, Chan, H T Claude, Kim, Jinny H, Vaughan, Andrew T, Forconi, Francesco, Beers, Stephen A
Published in The Journal of immunology (1950) (15.08.2018)
Published in The Journal of immunology (1950) (15.08.2018)
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Immunotherapy with Antibody-Targeted HLA Class I Complexes: Results of in vivo Tumour Cell Killing and Therapeutic Vaccination
Savage, Philip, Dyson, Julian, Milrain, Maggie, Mathews, Douglas, King, Ben, Chan, H.T. Claude, Barber, Linda, Epenetos, Agamemnon, Ogg, Graham, McMichael, Andrew, Glennie, Martin J., French, Ruth R.
Published in Tumor biology (01.01.2007)
Published in Tumor biology (01.01.2007)
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Journal Article
CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help
Glennie, Martin J, French, Ruth R, Chan, H.T. Claude, Tutt, Alison L
Published in Nature medicine (01.05.1999)
Published in Nature medicine (01.05.1999)
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