Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors
Horton, Sarah J., Giotopoulos, George, Yun, Haiyang, Vohra, Shabana, Sheppard, Olivia, Bashford-Rogers, Rachael, Rashid, Mamunur, Clipson, Alexandra, Chan, Wai-In, Sasca, Daniel, Yiangou, Loukia, Osaki, Hikari, Basheer, Faisal, Gallipoli, Paolo, Burrows, Natalie, Erdem, Ayşegül, Sybirna, Anastasiya, Foerster, Sarah, Zhao, Wanfeng, Sustic, Tonci, Petrunkina Harrison, Anna, Laurenti, Elisa, Okosun, Jessica, Hodson, Daniel, Wright, Penny, Smith, Ken G., Maxwell, Patrick, Fitzgibbon, Jude, Du, Ming Q., Adams, David J., Huntly, Brian J. P.
Published in Nature cell biology (01.09.2017)
Published in Nature cell biology (01.09.2017)
Get full text
Journal Article
Peruvoside, a Cardiac Glycoside, Induces Primitive Myeloid Leukemia Cell Death
Feng, Qian, Leong, Wa Seng, Liu, Liang, Chan, Wai-In
Published in Molecules (Basel, Switzerland) (22.04.2016)
Published in Molecules (Basel, Switzerland) (22.04.2016)
Get full text
Journal Article
The Transcriptional Coactivator Cbp Regulates Self-Renewal and Differentiation in Adult Hematopoietic Stem Cells
Chan, Wai-In, Hannah, Rebecca L., Dawson, Mark A., Pridans, Clare, Foster, Donna, Joshi, Anagha, Göttgens, Berthold, Van Deursen, Jan M., Huntly, Brian J. P.
Published in Molecular and Cellular Biology (01.12.2011)
Published in Molecular and Cellular Biology (01.12.2011)
Get full text
Journal Article
Common and Overlapping Oncogenic Pathways Contribute to the Evolution of Acute Myeloid Leukemias
KVINLAUG, Brynn T, CHAN, Wai-In, DE SILVA, Inusha, VALK, Peter J. M, DELWEL, Ruud, ARMSTRONG, Scott A, DÖHNER, Hartmut, GILLILAND, D. Gary, HUNTLY, Brian J. P, BULLINGER, Lars, RAMASWAMI, Mukundhan, SEARS, Christopher, FOSTER, Donna, LAZIC, Stanley E, OKABE, Rachel, BENNER, Axel, LEE, Benjamin H
Published in Cancer research (Chicago, Ill.) (15.06.2011)
Published in Cancer research (Chicago, Ill.) (15.06.2011)
Get full text
Journal Article
Genome-wide analysis of transcriptional reprogramming in mouse models of acute myeloid leukaemia
Bonadies, Nicolas, Foster, Samuel D, Chan, Wai-In, Kvinlaug, Brynn T, Spensberger, Dominik, Dawson, Mark A, Spooncer, Elaine, Whetton, Anthony D, Bannister, Andrew J, Huntly, Brian J, Göttgens, Berthold
Published in PloS one (28.01.2011)
Published in PloS one (28.01.2011)
Get full text
Journal Article
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
Dawson, Mark A., Prinjha, Rab K., Dittmann, Antje, Giotopoulos, George, Bantscheff, Marcus, Chan, Wai-In, Robson, Samuel C., Chung, Chun-wa, Hopf, Carsten, Savitski, Mikhail M., Huthmacher, Carola, Gudgin, Emma, Lugo, Dave, Beinke, Soren, Chapman, Trevor D., Roberts, Emma J., Soden, Peter E., Auger, Kurt R., Mirguet, Olivier, Doehner, Konstanze, Delwel, Ruud, Burnett, Alan K., Jeffrey, Phillip, Drewes, Gerard, Lee, Kevin, Huntly, Brian J. P., Kouzarides, Tony
Published in Nature (London) (27.10.2011)
Published in Nature (London) (27.10.2011)
Get full text
Journal Article
A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression
Giotopoulos, George, van der Weyden, Louise, Osaki, Hikari, Rust, Alistair G, Gallipoli, Paolo, Meduri, Eshwar, Horton, Sarah J, Chan, Wai-In, Foster, Donna, Prinjha, Rab K, Pimanda, John E, Tenen, Daniel G, Vassiliou, George S, Koschmieder, Steffen, Adams, David J, Huntly, Brian J P
Published in The Journal of experimental medicine (21.09.2015)
Published in The Journal of experimental medicine (21.09.2015)
Get full text
Journal Article
Targeting of Slc25a21 is associated with orofacial defects and otitis media due to disrupted expression of a neighbouring gene
Maguire, Simon, Estabel, Jeanne, Ingham, Neil, Pearson, Selina, Ryder, Edward, Carragher, Damian M, Walker, Nicolas, Bussell, James, Chan, Wai-In, Keane, Thomas M, Adams, David J, Scudamore, Cheryl L, Lelliott, Christopher J, Ramírez-Solis, Ramiro, Karp, Natasha A, Steel, Karen P, White, Jacqueline K, Gerdin, Anna-Karin
Published in PloS one (18.03.2014)
Published in PloS one (18.03.2014)
Get full text
Journal Article
CIC, a member of a novel subfamily of the HMG-box superfamily, is transiently expressed in developing granule neurons
Lee, Ching-Jung, Chan, Wai-In, Cheung, Martin, Cheng, Yi-Chuan, Appleby, Vanessa J, Orme, Alex T, Scotting, Paul J
Published in Brain research. Molecular brain research. (15.10.2002)
Published in Brain research. Molecular brain research. (15.10.2002)
Get full text
Journal Article
Differential expression of SOX4 and SOX11 in medulloblastoma
LEE, Ching-Jung, APPLEBY, Vanessa J, ORME, Alex T, CHAN, Wai-In, SCOTTING, Paul J
Published in Journal of neuro-oncology (01.05.2002)
Published in Journal of neuro-oncology (01.05.2002)
Get full text
Journal Article
Novel strategy to study gene expression and function in developing cerebellar granule cells
Yang, Zeng-jie, Appleby, Vanessa J., Coyle, Beth, Chan, Wai-In, Tahmaseb, Mohammad, Wigmore, Peter M., Scotting, Paul J.
Published in Journal of neuroscience methods (30.01.2004)
Published in Journal of neuroscience methods (30.01.2004)
Get full text
Journal Article
The Epigenetic Regulators CBP and p300 Facilitate Leukemogenesis and Represent Therapeutic Targets In Acute Myeloid Leukemia (AML)
Giotopoulos, George, Chan, Wai-In, Ruau, David, Gallipoli, Paolo, Fowler, Alexis, Göttgens, Berthold, Van Deursen, Jan, Cole, Philip, Huntly, Brian
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
Get full text
Journal Article
Modelling Cellular and Molecular Progression Of CML In The Mouse
Giotopoulos, George, Van Der Weyden, Louise, Osaki, Hikari, Chan, Wai-In, Rust, Alistair, Meduri, Eshwar, Koschmieder, Steffen, Tenen, Daniel, Vassiliou, George, Adams, David, Huntly, Brian
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
Get full text
Journal Article
Inhibition of BET Recruitment to Chromatin As An Effective Treatment for MLL-Fusion Leukaemia
Dawson, Mark A, Prinjha, Rab, Dittman, Antje, Giotopoulos, George, Bantscheff, Marcus, Chan, Wai-In, Robson, Samuel, Chung, Chun-wa, Hopf, Carsten, Savitski, Mikhail, Döhner, Konstanze, Burnett, Alan K, Delwel, Ruud, Carola, Huthmacher, Gudgin, Emma, Lugo, Dave, Beinke, Soren, Soden, Peter, Auger, Kurt R., Mirguet, Olivier, Jeffrey, Phillip, Drewes, Gerard, Lee, Kevin, Kouzarides, Tony, Huntly, Brian J.P.
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
Get full text
Journal Article
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
Dawson, Mark A, Prinjha, Rab K, Dittmann, Antje, Giotopoulos, George, Bantscheff, Marcus, Chan, Wai-In, Robson, Samuel C, Chung, Chun-wa, Hopf, Carsten, Savitski, Mikhail M, Huthmacher, Carola, Gudgin, Emma, Lugo, Dave, Beinke, Soren, Chapman, Trevor D, Roberts, Emma J, Soden, Peter E, Auger, Kurt R, Mirguet, Olivier, Doehner, Konstanze, Delwel, Ruud, Burnett, Alan K, Jeffrey, Phillip, Drewes, Gerard, Lee, Kevin, Huntly, Brian J.P, Kouzarides, Tony
Published in Nature (London) (27.10.2011)
Published in Nature (London) (27.10.2011)
Get full text
Journal Article
Targeting of Slc25a21 Is Associated with Orofacial Defects and Otitis Media Due to Disrupted Expression of a Neighbouring Gene: e91807
Maguire, Simon, Estabel, Jeanne, Ingham, Neil, Pearson, Selina, Ryder, Edward, Carragher, Damian M, Walker, Nicolas, Bussell, James, Chan, Wai-In
Published in PloS one (01.03.2014)
Published in PloS one (01.03.2014)
Get full text
Journal Article
Common Self-Renewal Pathways Contribute to the Induction of Acute Myeloid Leukemias Associated with Different Oncogenes
Kvinlaug, Brynn T, Chan, Wai-In, Bullinger, Lars, Sears, Christopher, Paul, Donna, Okabe, Rachel, Lee, Benjamin H, De Silva, Inusha, Armstrong, Scott, Dohner, Hartmut, Gilliland, D. Gary, Huntly, Brian JP
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
Get full text
Journal Article