Plasma DNA End-Motif Profiling as a Fragmentomic Marker in Cancer, Pregnancy, and Transplantation
Jiang, Peiyong, Sun, Kun, Peng, Wenlei, Cheng, Suk Hang, Ni, Meng, Yeung, Philip C, Heung, Macy M S, Xie, Tingting, Shang, Huimin, Zhou, Ze, Chan, Rebecca W Y, Wong, John, Wong, Vincent W S, Poon, Liona C, Leung, Tak Yeung, Lam, W K Jacky, Chan, Jason Y K, Chan, Henry L Y, Chan, K C Allen, Chiu, Rossa W K, Lo, Y M Dennis
Published in Cancer discovery (01.05.2020)
Published in Cancer discovery (01.05.2020)
Get full text
Journal Article
Effects of nucleases on cell-free extrachromosomal circular DNA
Sin, Sarah Tk, Deng, Jiaen, Ji, Lu, Yukawa, Masashi, Chan, Rebecca Wy, Volpi, Stefano, Vaglio, Augusto, Fenaroli, Paride, Bocca, Paola, Cheng, Suk Hang, Wong, Danny Kl, Lui, Kathy O, Jiang, Peiyong, Chan, K C Allen, Chiu, Rossa Wk, Lo, Y M Dennis
Published in JCI insight (22.04.2022)
Published in JCI insight (22.04.2022)
Get full text
Journal Article
Presence of Donor-Derived DNA and Cells in the Urine of Sex-Mismatched Hematopoietic Stem Cell Transplant Recipients: Implication for the Transrenal Hypothesis
Hung, Emily C.W, Shing, Tristan K.F, Chim, Stephen S.C, Yeung, Philip C, Chan, Rebecca W.Y, Chik, Ki W, Lee, Vincent, Tsui, Nancy B.Y, Li, Chi-Kong, Wong, Cesar S.C, Chiu, Rossa W.K, Lo, Y.M. Dennis
Published in Clinical chemistry (Baltimore, Md.) (01.04.2009)
Published in Clinical chemistry (Baltimore, Md.) (01.04.2009)
Get full text
Journal Article
Aberrant Concentrations of Liver-Derived Plasma Albumin mRNA in Liver Pathologies
Chan, Rebecca W.Y, Wong, John, Chan, Henry L.Y, Mok, Tony S.K, Lo, Wyatt Y.W, Lee, Vincent, To, Ka F, Lai, Paul B.S, Rainer, Timothy H, Lo, Y.M. Dennis, Chiu, Rossa W.K
Published in Clinical chemistry (Baltimore, Md.) (01.01.2010)
Published in Clinical chemistry (Baltimore, Md.) (01.01.2010)
Get full text
Journal Article
Dnase1l3 deletion causes aberrations in length and end-motif frequencies in plasma DNA
Serpas, Lee, Chan, Rebecca W. Y., Jiang, Peiyong, Ni, Meng, Sun, Kun, Rashidfarrokhi, Ali, Soni, Chetna, Sisirak, Vanja, Lee, Wing-Shan, Cheng, Suk Hang, Peng, Wenlei, Chan, K. C. Allen, Chiu, Rossa W. K., Reizis, Boris, Lo, Y. M. Dennis
Published in Proceedings of the National Academy of Sciences - PNAS (08.01.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (08.01.2019)
Get full text
Journal Article
Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments
Sun, Kun, Jiang, Peiyong, Chan, K. C. Allen, Wong, John, Cheng, Yvonne K. Y., Liang, Raymond H. S., Chan, Wai-kong, Ma, Edmond S. K., Chan, Stephen L., Cheng, Suk Hang, Chan, Rebecca W. Y., Tong, Yu K., Ng, Simon S. M., Wong, Raymond S. M., Hui, David S. C., Leung, Tse Ngong, Leung, Tak Y., Lai, Paul B. S., Chiu, Rossa W. K., Lo, Yuk Ming Dennis
Published in Proceedings of the National Academy of Sciences - PNAS (06.10.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (06.10.2015)
Get full text
Journal Article
Detection and characterization of jagged ends of double-stranded DNA in plasma
Jiang, Peiyong, Xie, Tingting, Ding, Spencer C, Zhou, Ze, Cheng, Suk Hang, Chan, Rebecca W Y, Lee, Wing-Shan, Peng, Wenlei, Wong, John, Wong, Vincent W S, Chan, Henry L Y, Chan, Stephen L, Poon, Liona C Y, Leung, Tak Y, Chan, K C Allen, Chiu, Rossa W K, Lo, Y M Dennis
Published in Genome research (01.08.2020)
Published in Genome research (01.08.2020)
Get full text
Journal Article
Epigenetic analysis of cell-free DNA by fragmentomic profiling
Zhou, Qing, Kang, Guannan, Jiang, Peiyong, Qiao, Rong, Lam, W. K. Jacky, Yu, Stephanie C. Y., Ma, Mary-Jane L., Ji, Lu, Cheng, Suk Hang, Gai, Wanxia, Peng, Wenlei, Shang, Huimin, Chan, Rebecca W. Y., Chan, Stephen L., Wong, Grace L. H., Hiraki, Linda T., Volpi, Stefano, Wong, Vincent W. S., Wong, John, Chiu, Rossa W. K., Chan, K. C. Allen, Lo, Y. M. Dennis
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.2022)
Get full text
Journal Article
Plasma DNA Profile Associated with DNASE1L3 Gene Mutations: Clinical Observations, Relationships to Nuclease Substrate Preference, and In Vivo Correction
Chan, Rebecca W.Y., Serpas, Lee, Ni, Meng, Volpi, Stefano, Hiraki, Linda T., Tam, Lai-Shan, Rashidfarrokhi, Ali, Wong, Priscilla C.H., Tam, Lydia H.P., Wang, Yueyang, Jiang, Peiyong, Cheng, Alice S.H., Peng, Wenlei, Han, Diana S.C., Tse, Patty P.P., Lau, Pik Ki, Lee, Wing-Shan, Magnasco, Alberto, Buti, Elisa, Sisirak, Vanja, AlMutairi, Nora, Chan, K.C. Allen, Chiu, Rossa W.K., Reizis, Boris, Lo, Y.M. Dennis
Published in American journal of human genetics (05.11.2020)
Published in American journal of human genetics (05.11.2020)
Get full text
Journal Article
Plasma DNA aberrations in systemic lupus erythematosus revealed by genomic and methylomic sequencing
Chan, Rebecca W Y, Jiang, Peiyong, Peng, Xianlu, Tam, Lai-Shan, Liao, Gary J W, Li, Edmund K M, Wong, Priscilla C H, Sun, Hao, Chan, K C Allen, Chiu, Rossa W K, Lo, Y M Dennis
Published in Proceedings of the National Academy of Sciences - PNAS (09.12.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (09.12.2014)
Get full text
Journal Article
Jagged Ends on Multinucleosomal Cell-Free DNA Serve as a Biomarker for Nuclease Activity and Systemic Lupus Erythematosus
Ding, Spencer C, Chan, Rebecca W Y, Peng, Wenlei, Huang, Liangbo, Zhou, Ze, Hu, Xi, Volpi, Stefano, Hiraki, Linda T, Vaglio, Augusto, Fenaroli, Paride, Bocca, Paola, Tam, Lai Shan, Wong, Priscilla C H, Tam, Lydia H P, Jiang, Peiyong, Chiu, Rossa W K, Allen Chan, K C, Dennis Lo, Y M
Published in Clinical chemistry (Baltimore, Md.) (03.07.2022)
Published in Clinical chemistry (Baltimore, Md.) (03.07.2022)
Get full text
Journal Article
Fragmentation landscape of cell-free DNA revealed by deconvolutional analysis of end motifs
Zhou, Ze, Ma, Mary-Jane L, Chan, Rebecca W Y, Lam, W K Jacky, Peng, Wenlei, Gai, Wanxia, Hu, Xi, Ding, Spencer C, Ji, Lu, Zhou, Qing, Cheung, Peter P H, Yu, Stephanie C Y, Teoh, Jeremy Y C, Szeto, Cheuk-Chun, Wong, John, Wong, Vincent W S, Wong, Grace L H, Chan, Stephen L, Hui, Edwin P, Ma, Brigette B Y, Chan, Anthony T C, Chiu, Rossa W K, Chan, K C Allen, Lo, Y M Dennis, Jiang, Peiyong
Published in Proceedings of the National Academy of Sciences - PNAS (25.04.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (25.04.2023)
Get full text
Journal Article
Genomic origin, fragmentomics, and transcriptional properties of long cell-free DNA molecules in human plasma
Che, Huiwen, Jiang, Peiyong, Choy, L Y Lois, Cheng, Suk Hang, Peng, Wenlei, Chan, Rebecca W Y, Liu, Jing, Zhou, Qing, Lam, W K Jacky, Yu, Stephanie C Y, Lau, So Ling, Leung, Tak Y, Wong, John, Wong, Vincent Wai-Sun, Wong, Grace L H, Chan, Stephen L, Chan, K C Allen, Lo, Y M Dennis
Published in Genome research (01.02.2024)
Published in Genome research (01.02.2024)
Get full text
Journal Article
DNA of Erythroid Origin Is Present in Human Plasma and Informs the Types of Anemia
Lam, W K Jacky, Gai, Wanxia, Sun, Kun, Wong, Raymond S M, Chan, Rebecca W Y, Jiang, Peiyong, Chan, Natalie P H, Hui, Winnie W I, Chan, Anthony W H, Szeto, Cheuk-Chun, Ng, Siew C, Law, Man-Fai, Chan, K C Allen, Chiu, Rossa W K, Lo, Y M Dennis
Published in Clinical chemistry (Baltimore, Md.) (01.10.2017)
Published in Clinical chemistry (Baltimore, Md.) (01.10.2017)
Get full text
Journal Article
Nuclease deficiencies alter plasma cell-free DNA methylation profiles
Han, Diana S C, Ni, Meng, Chan, Rebecca W Y, Wong, Danny K L, Hiraki, Linda T, Volpi, Stefano, Jiang, Peiyong, Lui, Kathy O, Chan, K C Allen, Chiu, Rossa W K, Lo, Y M Dennis
Published in Genome research (01.11.2021)
Published in Genome research (01.11.2021)
Get full text
Journal Article
Fragment Ends of Circulating Microbial DNA as Signatures for Pathogen Detection in Sepsis
Wang, Guangya, Lam, W K Jacky, Ling, Lowell, Ma, Mary-Jane L, Ramakrishnan, Saravanan, Chan, Don C T, Lee, Wing-Shan, Cheng, Suk Hang, Chan, Rebecca W Y, Yu, Stephanie C Y, Tse, Irene O L, Wong, Wai Tat, Jiang, Peiyong, Chiu, Rossa W K, Allen Chan, K C, Lo, Y M Dennis
Published in Clinical chemistry (Baltimore, Md.) (01.02.2023)
Published in Clinical chemistry (Baltimore, Md.) (01.02.2023)
Get full text
Journal Article
High-resolution analysis for urinary DNA jagged ends
Xie, Tingting, Wang, Guangya, Ding, Spencer C., Lee, Wing-Shan, Cheng, Suk Hang, Chan, Rebecca W. Y., Zhou, Ze, Ma, Mary-Jane L., Han, Diana S. C., Teoh, Jeremy Y. C., Lam, W. K. Jacky, Jiang, Peiyong, Chiu, Rossa W. K., Chan, K. C. Allen, Lo, Y. M. Dennis
Published in Npj genomic medicine (23.02.2022)
Published in Npj genomic medicine (23.02.2022)
Get full text
Journal Article