Cellular heterogeneity and plasticity in liver cancer
Chan, Lo-Kong, Tsui, Yu-Man, Ho, Daniel Wai-Hung, Ng, Irene Oi-Lin
Published in Seminars in cancer biology (01.07.2022)
Published in Seminars in cancer biology (01.07.2022)
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Single-cell RNA sequencing shows the immunosuppressive landscape and tumor heterogeneity of HBV-associated hepatocellular carcinoma
Ho, Daniel Wai-Hung, Tsui, Yu-Man, Chan, Lo-Kong, Sze, Karen Man-Fong, Zhang, Xin, Cheu, Jacinth Wing-Sum, Chiu, Yung-Tuen, Lee, Joyce Man-Fong, Chan, Albert Chi-Yan, Cheung, Elaine Tin-Yan, Yau, Derek Tsz-Wai, Chia, Nam-Hung, Lo, Irene Lai-Oi, Sham, Pak-Chung, Cheung, Tan-To, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin
Published in Nature communications (17.06.2021)
Published in Nature communications (17.06.2021)
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Single-cell transcriptomics reveals the landscape of intra-tumoral heterogeneity and stemness-related subpopulations in liver cancer
Ho, Daniel Wai-Hung, Tsui, Yu-Man, Sze, Karen Man-Fong, Chan, Lo-Kong, Cheung, Tan-To, Lee, Eva, Sham, Pak-Chung, Tsui, Stephen Kwok-Wing, Lee, Terence Kin-Wah, Ng, Irene Oi-Lin
Published in Cancer letters (10.09.2019)
Published in Cancer letters (10.09.2019)
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Joining the dots for better liver cancer treatment
Chan, Lo-Kong, Ng, Irene Oi-Lin
Published in Nature reviews. Gastroenterology & hepatology (01.02.2020)
Published in Nature reviews. Gastroenterology & hepatology (01.02.2020)
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Journal Article
Dysregulation of RalA signaling through dual regulatory mechanisms exerts its oncogenic functions in hepatocellular carcinoma
Tian, Lu, Zhao, Luqing, Sze, Karen Man‐Fong, Kam, Charles Shing, Ming, Vanessa Sheung‐In, Wang, Xia, Zhang, Vanilla Xin, Ho, Daniel Wai‐Hung, Cheung, Tan‐To, Chan, Lo‐Kong, Ng, Irene Oi‐Lin
Published in Hepatology (Baltimore, Md.) (01.07.2022)
Published in Hepatology (Baltimore, Md.) (01.07.2022)
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Hepatitis B Virus–Telomerase Reverse Transcriptase Promoter Integration Harnesses Host ELF4, Resulting in Telomerase Reverse Transcriptase Gene Transcription in Hepatocellular Carcinoma
Sze, Karen Man‐Fong, Ho, Daniel Wai‐Hung, Chiu, Yung‐Tuen, Tsui, Yu‐Man, Chan, Lo‐Kong, Lee, Joyce Man‐Fong, Chok, Kenneth Siu‐Ho, Chan, Albert Chi‐Yan, Tang, Chung‐Ngai, Tang, Victor Wai‐Lun, Lo, Irene Lai‐Oi, Yau, Derek Tsz‐Wai, Cheung, Tan‐To, Ng, Irene Oi‐Lin
Published in Hepatology (Baltimore, Md.) (01.01.2021)
Published in Hepatology (Baltimore, Md.) (01.01.2021)
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Antioxidant supplements promote tumor formation and growth and confer drug resistance in hepatocellular carcinoma by reducing intracellular ROS and induction of TMBIM1
Zhang, Vanilla Xin, Sze, Karen Man-Fong, Chan, Lo-Kong, Ho, Daniel Wai-Hung, Tsui, Yu-Man, Chiu, Yung-Tuen, Lee, Eva, Husain, Abdullah, Huang, Hongyang, Tian, Lu, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin
Published in Cell & bioscience (19.12.2021)
Published in Cell & bioscience (19.12.2021)
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Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration
Liu, Jessica Aijia, Rao, Yanxia, Cheung, May Pui Lai, Hui, Man-Ning, Wu, Ming-Hoi, Chan, Lo-Kong, Ng, Irene Oi-Lin, Niu, Ben, Cheah, Kathryn S E, Sharma, Rakesh, Hodgson, Louis, Cheung, Martin
Published in Nature communications (30.10.2017)
Published in Nature communications (30.10.2017)
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Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma
Chiu, Yung-Tuen, Wong, John K.L, Choi, Shing-Wan, Sze, Karen M.F, Ho, Daniel W.H, Chan, Lo-Kong, Lee, Joyce M.F, Man, Kwan, Cherny, Stacey, Yang, Wan-Ling, Wong, Chun-Ming, Sham, Pak-Chung, Ng, Irene O.L
Published in Journal of hepatology (01.06.2016)
Published in Journal of hepatology (01.06.2016)
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Akt phosphorylation of deleted in liver cancer 1 abrogates its suppression of liver cancer tumorigenesis and metastasis
Ko, Frankie Chi Fat, Chan, Lo-Kong, Tung, Edmund Kwok-Kwan, Lowe, Scott W, Ng, Irene Oi-Lin, Yam, Judy Wai Ping
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2010)
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2010)
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SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop
Cui, Chun-Ping, Wong, Carmen Chak-Lui, Kai, Alan Ka-Lun, Ho, Daniel Wai-Hung, Lau, Eunice Yuen-Ting, Tsui, Yu-Man, Chan, Lo-Kong, Cheung, Tan-To, Chok, Kenneth Siu-Ho, Chan, Albert C Y, Lo, Regina Cheuk-Lam, Lee, Joyce Man-Fong, Lee, Terence Kin-Wah, Ng, Irene Oi Lin
Published in Gut (01.12.2017)
Published in Gut (01.12.2017)
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Ephrin-A3/EphA2 axis regulates cellular metabolic plasticity to enhance cancer stemness in hypoxic hepatocellular carcinoma
Husain, Abdullah, Chiu, Yung-Tuen, Sze, Karen Man-Fong, Ho, Daniel Wai-Hung, Tsui, Yu-Man, Suarez, Eliana Mary Senires, Zhang, Vanilla Xin, Chan, Lo-Kong, Lee, Eva, Lee, Joyce Man-Fong, Cheung, Tan-To, Wong, Carmen Chak-Lui, Chung, Clive Yik-Sham, Ng, Irene Oi-Lin
Published in Journal of hepatology (01.08.2022)
Published in Journal of hepatology (01.08.2022)
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Down‐regulation of TIMP2 by HIF‐1α/miR‐210/HIF‐3α regulatory feedback circuit enhances cancer metastasis in hepatocellular carcinoma
Kai, Alan Ka‐Lun, Chan, Lo Kong, Lo, Regina Cheuk‐Lam, Lee, Joyce Man‐Fong, Wong, Carmen Chak‐Lui, Wong, Jack Chun‐Ming, Ng, Irene Oi‐Lin
Published in Hepatology (Baltimore, Md.) (01.08.2016)
Published in Hepatology (Baltimore, Md.) (01.08.2016)
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Journal Article
Deleted in liver cancer 1 isoforms are distinctly expressed in human tissues, functionally different and under differential transcriptional regulation in hepatocellular carcinoma
Ko, Frankie Chi Fat, Yeung, Yin-Shan, Wong, Chun-Ming, Chan, Lo-Kong, Poon, Ronnie Tung Ping, Oi-Lin Ng, Irene, Yam, Judy Wai Ping
Published in Liver international (01.01.2010)
Published in Liver international (01.01.2010)
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