proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates
Chan, Joyce C.Y, Piper, Derek E, Cao, Qiong, Liu, Dongming, King, Chadwick, Wang, Wei, Tang, Jie, Liu, Qiang, Higbee, Jared, Xia, Zhen, Di, Yongmei, Shetterly, Susan, Arimura, Ziva, Salomonis, Heather, Romanow, William G, Thibault, Stephen T, Zhang, Richard, Cao, Ping, Yang, Xiao-Ping, Yu, Timothy, Lu, Mei, Retter, Marc W, Kwon, Gayle, Henne, Kirk, Pan, Oscar, Tsai, Mei-Mei, Fuchslocher, Bryna, Yang, Evelyn, Zhou, Lei, Lee, Ki Jeong, Daris, Mark, Sheng, Jackie, Wang, Yan, Shen, Wenyan D, Yeh, Wen-Chen, Emery, Maurice, Walker, Nigel P.C, Shan, Bei, Schwarz, Margrit, Jackson, Simon M
Published in Proceedings of the National Academy of Sciences - PNAS (16.06.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (16.06.2009)
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Combined factor VII/protein C deficiency results in intrauterine coagulopathy in mice
Chan, J C, Cornelissen, I, Collen, D, Ploplis, V A, Castellino, F J
Published in The Journal of clinical investigation (01.04.2000)
Published in The Journal of clinical investigation (01.04.2000)
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Half-life extension of peptidic APJ agonists by N-terminal lipid conjugation
Reed, Anthony B., Lanman, Brian A., Holder, Jerry Ryan, Yang, Bryant H., Ma, Ji, Humphreys, Sara C., Wang, Zhican, Chan, Joyce C.Y., Miranda, Les P., Swaminath, Gayathri, Allen, John G.
Published in Bioorganic & medicinal chemistry letters (01.11.2020)
Published in Bioorganic & medicinal chemistry letters (01.11.2020)
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Anti-PCSK9 antibody pharmacokinetics and low-density lipoprotein-cholesterol pharmacodynamics in nonhuman primates are antigen affinity-dependent and exhibit limited sensitivity to neonatal Fc receptor-binding enhancement
Henne, Kirk R, Ason, Brandon, Howard, Monique, Wang, Wei, Sun, Jeonghoon, Higbee, Jared, Tang, Jie, Matsuda, Katherine C, Xu, Ren, Zhou, Lei, Chan, Joyce C Y, King, Chadwick, Piper, Derek E, Ketchem, Randal R, Michaels, Mark Leo, Jackson, Simon M, Retter, Marc W
Published in The Journal of pharmacology and experimental therapeutics (01.04.2015)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2015)
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Mice lacking factor VII develop normally but suffer fatal perinatal bleeding
Collen, Désiré, Rosen, Elliot D, Chan, Joyce C. Y, Idusogie, Esohe, Clotman, Frédéric, Vlasuk, George, Luther, Thomas, Jalbert, Louise R, Albrecht, Sybille, Zhong, Liang, Lissens, Ann, Schoonjans, Luc, Moons, Lieve, Castellino, Francis J, Carmeliet, Peter
Published in Nature (London) (20.11.1997)
Published in Nature (London) (20.11.1997)
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Factor VII deficiency rescues the intrauterine lethality in mice associated with a tissue factor pathway inhibitor deficit
Chan, J C, Carmeliet, P, Moons, L, Rosen, E D, Huang, Z F, Broze, Jr, G J, Collen, D, Castellino, F J
Published in The Journal of clinical investigation (01.02.1999)
Published in The Journal of clinical investigation (01.02.1999)
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The Characterization of Mice with a Targeted Combined Deficiency of Protein C and Factor XI
Chan, Joyce C.Y., Ganopolsky, Jorge G., Cornelissen, Ivo, Suckow, Mark A., Sandoval-Cooper, Mayra J., Brown, Erica C., Noria, Francisco, Gailani, David, Rosen, Elliot D., Ploplis, Victoria A., Castellino, Francis J.
Published in The American journal of pathology (01.02.2001)
Published in The American journal of pathology (01.02.2001)
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The Hydrophobic Nature of Residue-5 of Human Protein C Is a Major Determinant of Its Functional Interactions with Acidic Phospholipid Vesicles
Jalbert, Louise R, Chan, Joyce C. Y, Christiansen, William T, Castellino, Francis J
Published in Biochemistry (Easton) (04.06.1996)
Published in Biochemistry (Easton) (04.06.1996)
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