WRN helicase is a synthetic lethal target in microsatellite unstable cancers
Chan, Edmond M., Shibue, Tsukasa, McFarland, James M., Gaeta, Benjamin, Ghandi, Mahmoud, Dumont, Nancy, Gonzalez, Alfredo, McPartlan, Justine S., Li, Tianxia, Zhang, Yanxi, Bin Liu, Jie, Lazaro, Jean-Bernard, Gu, Peili, Piett, Cortt G., Apffel, Annie, Ali, Syed O., Deasy, Rebecca, Keskula, Paula, Ng, Raymond W. S., Roberts, Emma A., Reznichenko, Elizaveta, Leung, Lisa, Alimova, Maria, Schenone, Monica, Islam, Mirazul, Maruvka, Yosef E., Liu, Yang, Roper, Jatin, Raghavan, Srivatsan, Giannakis, Marios, Tseng, Yuen-Yi, Nagel, Zachary D., D’Andrea, Alan, Root, David E., Boehm, Jesse S., Getz, Gad, Chang, Sandy, Golub, Todd R., Tsherniak, Aviad, Vazquez, Francisca, Bass, Adam J.
Published in Nature (London) (01.04.2019)
Published in Nature (London) (01.04.2019)
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Journal Article
Generation of a triple-gene knockout mammalian cell line using engineered zinc-finger nucleases
Liu, Pei-Qi, Chan, Edmond M, Cost, Gregory J, Zhang, Lin, Wang, Jianbin, Miller, Jeffrey C, Guschin, Dmitry Y, Reik, Andreas, Holmes, Michael C, Mott, John E, Collingwood, Trevor N, Gregory, Philip D
Published in Biotechnology and bioengineering (01.05.2010)
Published in Biotechnology and bioengineering (01.05.2010)
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Journal Article
Repeat expansions confer WRN dependence in microsatellite-unstable cancers
van Wietmarschen, Niek, Sridharan, Sriram, Nathan, William J., Tubbs, Anthony, Chan, Edmond M., Callen, Elsa, Wu, Wei, Belinky, Frida, Tripathi, Veenu, Wong, Nancy, Foster, Kyla, Noorbakhsh, Javad, Garimella, Kiran, Cruz-Migoni, Abimael, Sommers, Joshua A., Huang, Yongqing, Borah, Ashir A., Smith, Jonathan T., Kalfon, Jeremie, Kesten, Nikolas, Fugger, Kasper, Walker, Robert L., Dolzhenko, Egor, Eberle, Michael A., Hayward, Bruce E., Usdin, Karen, Freudenreich, Catherine H., Brosh, Robert M., West, Stephen C., McHugh, Peter J., Meltzer, Paul S., Bass, Adam J., Nussenzweig, André
Published in Nature (London) (08.10.2020)
Published in Nature (London) (08.10.2020)
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Journal Article
Systematic RNA interference reveals that oncogenic KRAS -driven cancers require TBK1
Kim, So Young, Sabatini, David M, Michel, Kathrin, Tamayo, Pablo, Weir, Barbara A, Le, Hanh, Mermel, Craig, Gupta, Piyush B, Meyerson, Matthew, Hahn, William C, Schinzel, Anna C, Hoersch, Sebastian, Lander, Eric S, Sandy, Peter, Mesirov, Jill P, Sheng, Qing, Boehm, Jesse S, Meylan, Etienne, Gilliland, D. Gary, Barbie, David A, Sos, Martin L, Fröhling, Stefan, Chan, Edmond M, Wittner, Ben S, Ramaswamy, Sridhar, Livingston, David M, Root, David E, Reiling, Jan H, Wadlow, Raymond C, Dunn, Ian F, Thomas, Roman K, Scholl, Claudia, Moody, Susan E, Silver, Serena J, Jacks, Tyler
Published in Nature (London) (05.11.2009)
Published in Nature (London) (05.11.2009)
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Journal Article
Mapping multimodal phenotypes to perturbations in cells and tissue with CRISPRmap
Gu, Jiacheng, Iyer, Abhishek, Wesley, Ben, Taglialatela, Angelo, Leuzzi, Giuseppe, Hangai, Sho, Decker, Aubrianna, Gu, Ruoyu, Klickstein, Naomi, Shuai, Yuanlong, Jankovic, Kristina, Parker-Burns, Lucy, Jin, Yinuo, Zhang, Jia Yi, Hong, Justin, Niu, Xiang, Costa, Jonathon A, Pezet, Mikael G, Chou, Jacqueline, Snoeck, Hans-Willem, Landau, Dan A, Azizi, Elham, Chan, Edmond M, Ciccia, Alberto, Gaublomme, Jellert T
Published in Nature biotechnology (07.10.2024)
Published in Nature biotechnology (07.10.2024)
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Journal Article
Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit
Zhu, Zehua, Aref, Amir R, Cohoon, Travis J, Barbie, Thanh U, Imamura, Yu, Yang, Shenghong, Moody, Susan E, Shen, Rhine R, Schinzel, Anna C, Thai, Tran C, Reibel, Jacob B, Tamayo, Pablo, Godfrey, Jason T, Qian, Zhi Rong, Page, Asher N, Maciag, Karolina, Chan, Edmond M, Silkworth, Whitney, Labowsky, Mary T, Rozhansky, Lior, Mesirov, Jill P, Gillanders, William E, Ogino, Shuji, Hacohen, Nir, Gaudet, Suzanne, Eck, Michael J, Engelman, Jeffrey A, Corcoran, Ryan B, Wong, Kwok-Kin, Hahn, William C, Barbie, David A
Published in Cancer discovery (01.04.2014)
Published in Cancer discovery (01.04.2014)
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Journal Article
CRISPRmap: Sequencing-free optical pooled screens mapping multi-omic phenotypes in cells and tissue
Gu, Jiacheng, Iyer, Abhishek, Wesley, Ben, Taglialatela, Angelo, Leuzzi, Giuseppe, Hangai, Sho, Decker, Aubrianna, Gu, Ruoyu, Klickstein, Naomi, Shuai, Yuanlong, Jankovic, Kristina, Parker-Burns, Lucy, Jin, Yinuo, Zhang, Jia Yi, Hong, Justin, Niu, Steve, Chou, Jacqueline, Landau, Dan A, Azizi, Elham, Chan, Edmond M, Ciccia, Alberto, Gaublomme, Jellert T
Published in bioRxiv (26.12.2023)
Published in bioRxiv (26.12.2023)
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Journal Article
Paper
Design and Implement a Web News Retrieval System
Liu, James N. K., Luo, Weidong, Chan, Edmond M. C.
Published in Knowledge-Based Intelligent Information and Engineering Systems (2005)
Published in Knowledge-Based Intelligent Information and Engineering Systems (2005)
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Book Chapter
Conference Proceeding
Abstract 3364: PELO is a synthetic lethal target in chromosome 9p21-deleted or MSI cancers
Chan, Edmond M., Borck, Patricia, Bick, Nolan, Jankovic, Kristina, Boyle, Isabella, Parker-Burns, Lucy, Foster, Kyla, Lau, Anthony, Borah, Ashir, Dempster, Joshua, Vazquez, Francisca
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants
Fleischer, David M., MD, Sicherer, Scott, MD, Greenhawt, Matthew, MD, Campbell, Dianne, MB BS, FRACP, PhD, Chan, Edmond, MD, Muraro, Antonella, MD, PhD, Halken, Susanne, MD, Katz, Yitzhak, MD, Ebisawa, Motohiro, MD, PhD, Eichenfield, Lawrence, MD, Sampson, Hugh, MD, Lack, Gideon, MB, BCh, Du Toit, George, MB, BCh, Roberts, Graham, DM, Bahnson, Henry, MPH, Feeney, Mary, MSc, RD, Hourihane, Jonathan, MD, Spergel, Jonathan, MD, PhD, Young, Michael, MD, As'aad, Amal, MD, Allen, Katrina, BMedSc, MB BS, FRACP, PhD, Prescott, Susan, BMedSc, MB BS, FRACP, PhD, Kapur, Sandeep, MD, Saito, Hirohisa, MD, PhD, Agache, Ioana, MD, Akdis, Cezmi A., MD, PhD, Arshad, Hasan, MD, Beyer, Kirsten, MD, Dubois, Anthony, MD, Eigenmann, Philippe, MD, Fernandez-Rivas, Monserrat, MD, Grimshaw, Kate, PhD, RD, RNutr, Hoffman-Sommergruber, Karin, PhD, Host, Arne, MD, Lau, Susanne, MD, O'Mahony, Liam, MD, Mills, Clare, PhD, Papadopoulos, Nikolaus, MD, Venter, Carina, BSc, PhD, Agmon-Levin, Nancy, MD, Kessel, Aaron, MD, Antaya, Richard, MD, Drolet, Beth, MD, Rosenwasser, Lanny, MD
Published in Annals of allergy, asthma, & immunology (01.08.2015)
Published in Annals of allergy, asthma, & immunology (01.08.2015)
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Journal Article
Conference Proceeding
Initial and accidental reactions are managed inadequately in children with sesame allergy
Segal, Lauren, Ben-Shoshan, Moshe, Alizadehfar, Reza, Primeau, Marie-Noël, Asai, Yuka, Killorn, Katie R, Chan, Edmond, Cheuk, Stephen, Shand, Greg, St-Pierre, Yvan, Harada, Laurie, Clarke, Ann
Published in The journal of allergy and clinical immunology in practice (Cambridge, MA) (01.03.2017)
Published in The journal of allergy and clinical immunology in practice (Cambridge, MA) (01.03.2017)
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Journal Article
Early Solid Food Introduction: Role in Food Allergy Prevention and Implications for Breastfeeding
Abrams, Elissa M., MD, FRCPC, Greenhawt, Matthew, MD, MBA, MSc, Fleischer, David M., MD, FAAAAI, Chan, Edmond S., MD, FRCPC, FAAAAI
Published in The Journal of pediatrics (01.05.2017)
Published in The Journal of pediatrics (01.05.2017)
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Journal Article
Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases–sponsored expert panel
Togias, Alkis, MD, Cooper, Susan F., MSc, Acebal, Maria L., JD, Assa'ad, Amal, MD, Baker, James R., MD, Beck, Lisa A., MD, Block, Julie, Byrd-Bredbenner, Carol, PhD, RD, FAND, Chan, Edmond S., MD, FRCPC, Eichenfield, Lawrence F., MD, Fleischer, David M., MD, Fuchs, George J., MD, Furuta, Glenn T., MD, Greenhawt, Matthew J., MD, MBA, MSc, Gupta, Ruchi S., MD, MPH, Habich, Michele, DNP, APN/CNS, CPN, Jones, Stacie M., MD, Keaton, Kari, Muraro, Antonella, MD, PhD, Plaut, Marshall, MD, Rosenwasser, Lanny J., MD, Rotrosen, Daniel, MD, Sampson, Hugh A., MD, Schneider, Lynda C., MD, Sicherer, Scott H., MD, Sidbury, Robert, MD, MPH, Spergel, Jonathan, MD, PhD, Stukus, David R., MD, Venter, Carina, PhD, RD, Boyce, Joshua A., MD
Published in Annals of allergy, asthma, & immunology (01.02.2017)
Published in Annals of allergy, asthma, & immunology (01.02.2017)
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Journal Article
Egg-allergic patients can be safely vaccinated against influenza
Des Roches, Anne, MD, FRCPC, FAAAAI, Paradis, Louis, MD, FRCPC, FAAAAI, Gagnon, Remi, MD, FRCPC, Lemire, Chantal, MD, FRCPC, Bégin, Philippe, MD, FRCPC, MSc, Carr, Stuart, MD, FRCPC, FAAAAI, Chan, Edmond S., MD, FRCPC, FAAAAI, Paradis, Jean, MD, FRCPC, Frenette, Lyne, MD, FRCP, Ouakki, Manale, MSc, Benoît, Mélanie, BSc, De Serres, Gaston, MD, PhD
Published in Journal of allergy and clinical immunology (01.11.2012)
Published in Journal of allergy and clinical immunology (01.11.2012)
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Journal Article
Real-world safety and effectiveness analysis of low-dose preschool sesame oral immunotherapy
Chua, Gilbert T., Soller, Lianne, Kapur, Sandeep, McHenry, Mary, Rex, Gregory A., Cook, Victoria E., Cameron, Scott B., Chan, Edmond S., Yeung, Joanne, Erdle, Stephanie C.
Published in The journal of allergy and clinical immunology. Global (01.02.2024)
Published in The journal of allergy and clinical immunology. Global (01.02.2024)
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Journal Article
Allergic Background and Time to Diagnosis in Children with Eosinophilic Esophagitis in British Columbia
Mill, Christopher, BSc, MPH, Avinashi, Vishal, MD, MPH, Teoh, Timothy, BSc, Koo, Christopher, BSc, Chan, Edmond S., MD, FAAAAI
Published in Journal of allergy and clinical immunology (01.02.2016)
Published in Journal of allergy and clinical immunology (01.02.2016)
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Journal Article
Many Children Referred to a Tertiary Care Pediatric Allergy Clinic Do Not Have an Allergy
Cook, Victoria E., MD, Yeo, Jordan, Mill, Christopher, MSc, Hildebrand, Kyla, MD, Portales-Casamar, Elodie, PhD, Chan, Edmond S., MD, FAAAAI
Published in Journal of allergy and clinical immunology (01.02.2017)
Published in Journal of allergy and clinical immunology (01.02.2017)
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Journal Article
Rate and Management of Anaphylaxis in Adult Patients at a Tertiary Care Centre Emergency Department
Adatia, Adil, MD, Ben-Shoshan, Moshe, MD, MSc, Clarke, Ann E., MD, MSc, FRCPC, Chan, Edmond S., MD, FAAAAI, Shand, Greg, MSc, Delaney, Scott, MD, Yanishevsky, Yarden, MD, MRCPI, FACAAI, FAAAAI
Published in Journal of allergy and clinical immunology (01.02.2017)
Published in Journal of allergy and clinical immunology (01.02.2017)
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Journal Article