Improved detection of Zika virus RNA in human and animal specimens by a novel, highly sensitive and specific real‐time RT‐PCR assay targeting the 5′‐untranslated region of Zika virus
Chan, Jasper Fuk‐Woo, Yip, Cyril Chik‐Yan, Tee, Kah‐Meng, Zhu, Zheng, Tsang, Jessica Oi‐Ling, Chik, Kenn Ka‐Heng, Tsang, Terance Gi‐Wai, Chan, Chris Chung‐Sing, Poon, Vincent Kwok‐Man, Sridhar, Siddharth, Yin, Feifei, Hung, Ivan Fan‐Ngai, Chau, Sandy Ka‐Yee, Zhang, Anna Jinxia, Chan, Kwok‐Hung, Yuen, Kwok‐Yung
Published in Tropical medicine & international health (01.05.2017)
Published in Tropical medicine & international health (01.05.2017)
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Simulation of the Clinical and Pathological Manifestations of Coronavirus Disease 2019 (COVID-19) in a Golden Syrian Hamster Model: Implications for Disease Pathogenesis and Transmissibility
Chan, Jasper Fuk-Woo, Zhang, Anna Jinxia, Yuan, Shuofeng, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Lee, Andrew Chak-Yiu, Chan, Wan-Mui, Fan, Zhimeng, Tsoi, Hoi-Wah, Wen, Lei, Liang, Ronghui, Cao, Jianli, Chen, Yanxia, Tang, Kaiming, Luo, Cuiting, Cai, Jian-Piao, Kok, Kin-Hang, Chu, Hin, Chan, Kwok-Hung, Sridhar, Siddharth, Chen, Zhiwei, Chen, Honglin, To, Kelvin Kai-Wang, Yuen, Kwok-Yung
Published in Clinical Infectious Diseases (26.03.2020)
Published in Clinical Infectious Diseases (26.03.2020)
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Surgical Mask Partition Reduces the Risk of Noncontact Transmission in a Golden Syrian Hamster Model for Coronavirus Disease 2019 (COVID-19)
Chan, Jasper Fuk-Woo, Yuan, Shuofeng, Zhang, Anna Jinxia, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Lee, Andrew Chak-Yiu, Fan, Zhimeng, Li, Can, Liang, Ronghui, Cao, Jianli, Tang, Kaiming, Luo, Cuiting, Cheng, Vincent Chi-Chung, Cai, Jian-Piao, Chu, Hin, Chan, Kwok-Hung, To, Kelvin Kai-Wang, Sridhar, Siddharth, Yuen, Kwok-Yung
Published in Clinical infectious diseases (19.11.2020)
Published in Clinical infectious diseases (19.11.2020)
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Journal Article
Clofazimine broadly inhibits coronaviruses including SARS-CoV-2
Yuan, Shuofeng, Yin, Xin, Meng, Xiangzhi, Chan, Jasper Fuk-Woo, Ye, Zi-Wei, Riva, Laura, Pache, Lars, Chan, Chris Chun-Yiu, Lai, Pok-Man, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Lee, Andrew Chak-Yiu, Matsunaga, Naoko, Pu, Yuan, Yuen, Chun-Kit, Cao, Jianli, Liang, Ronghui, Tang, Kaiming, Sheng, Li, Du, Yushen, Xu, Wan, Lau, Chit-Ying, Sit, Ko-Yung, Au, Wing-Kuk, Wang, Runming, Zhang, Yu-Yuan, Tang, Yan-Dong, Clausen, Thomas Mandel, Pihl, Jessica, Oh, Juntaek, Sze, Kong-Hung, Zhang, Anna Jinxia, Chu, Hin, Kok, Kin-Hang, Wang, Dong, Cai, Xue-Hui, Esko, Jeffrey D., Hung, Ivan Fan-Ngai, Li, Ronald Adolphus, Chen, Honglin, Sun, Hongzhe, Jin, Dong-Yan, Sun, Ren, Chanda, Sumit K., Yuen, Kwok-Yung
Published in Nature (London) (20.05.2021)
Published in Nature (London) (20.05.2021)
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Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters
Yuan, Shuofeng, Ye, Zi-Wei, Liang, Ronghui, Tang, Kaiming, Zhang, Anna Jinxia, Lu, Gang, Ong, Chon Phin, Man Poon, Vincent Kwok, Chan, Chris Chung-Sing, Mok, Bobo Wing-Yee, Qin, Zhenzhi, Xie, Yubin, Chu, Allen Wing-Ho, Chan, Wan-Mui, Ip, Jonathan Daniel, Sun, Haoran, Tsang, Jessica Oi-Ling, Yuen, Terrence Tsz-Tai, Chik, Kenn Ka-Heng, Chan, Chris Chun-Yiu, Cai, Jian-Piao, Luo, Cuiting, Lu, Lu, Yip, Cyril Chik-Yan, Chu, Hin, To, Kelvin Kai-Wang, Chen, Honglin, Jin, Dong-Yan, Yuen, Kwok-Yung, Chan, Jasper Fuk-Woo
Published in Science (American Association for the Advancement of Science) (22.07.2022)
Published in Science (American Association for the Advancement of Science) (22.07.2022)
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Severe Acute Respiratory Syndrome Coronavirus 2 Infects and Damages the Mature and Immature Olfactory Sensory Neurons of Hamsters
Zhang, Anna Jinxia, Lee, Andrew Chak-Yiu, Chu, Hin, Chan, Jasper Fuk-Woo, Fan, Zhimeng, Li, Can, Liu, Feifei, Chen, Yanxia, Yuan, Shuofeng, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Cai, Jian-Piao, Wu, Kenneth Lap-Kei, Sridhar, Siddharth, Chan, Ying-Shing, Yuen, Kwok-Yung
Published in Clinical infectious diseases (15.07.2021)
Published in Clinical infectious diseases (15.07.2021)
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Coinfection by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza A(H1N1)pdm09 Virus Enhances the Severity of Pneumonia in Golden Syrian Hamsters
Zhang, Anna Jinxia, Lee, Andrew Chak-Yiu, Chan, Jasper Fuk-Woo, Liu, Feifei, Li, Can, Chen, Yanxia, Chu, Hin, Lau, Siu-Ying, Wang, Pui, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Yuan, Shuofeng, To, Kelvin Kai-Wang, Chen, Honglin, Yuen, Kwok-Yung
Published in Clinical infectious diseases (15.06.2021)
Published in Clinical infectious diseases (15.06.2021)
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Cross-linking peptide and repurposed drugs inhibit both entry pathways of SARS-CoV-2
Zhao, Hanjun, To, Kelvin K. W., Lam, Hoiyan, Zhou, Xinxin, Chan, Jasper Fuk-Woo, Peng, Zheng, Lee, Andrew C. Y., Cai, Jianpiao, Chan, Wan-Mui, Ip, Jonathan Daniel, Chan, Chris Chung-Sing, Yeung, Man Lung, Zhang, Anna Jinxia, Chu, Allen Wing Ho, Jiang, Shibo, Yuen, Kwok-Yung
Published in Nature communications (09.03.2021)
Published in Nature communications (09.03.2021)
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SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters
Qiao, Wei, Lau, Hui En, Xie, Huizhi, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Chu, Hin, Yuan, Shuofeng, Yuen, Terrence Tsz-Tai, Chik, Kenn Ka-Heng, Tsang, Jessica Oi-Ling, Chan, Chris Chun-Yiu, Cai, Jian-Piao, Luo, Cuiting, Yuen, Kwok-Yung, Cheung, Kenneth Man-Chee, Chan, Jasper Fuk-Woo, Yeung, Kelvin Wai-Kwok
Published in Nature communications (09.05.2022)
Published in Nature communications (09.05.2022)
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Journal Article
Novel antiviral activity and mechanism of bromocriptine as a Zika virus NS2B-NS3 protease inhibitor
Chan, Jasper Fuk-Woo, Chik, Kenn Ka-Heng, Yuan, Shuofeng, Yip, Cyril Chik-Yan, Zhu, Zheng, Tee, Kah-Meng, Tsang, Jessica Oi-Ling, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Lu, Gang, Zhang, Anna Jinxia, Lai, Kin-Kui, Chan, Kwok-Hung, Kao, Richard Yi-Tsun, Yuen, Kwok-Yung
Published in Antiviral research (01.05.2017)
Published in Antiviral research (01.05.2017)
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A broadly neutralizing antibody protects Syrian hamsters against SARS-CoV-2 Omicron challenge
Zhou, Biao, Zhou, Runhong, Tang, Bingjie, Chan, Jasper Fuk-Woo, Luo, Mengxiao, Peng, Qiaoli, Yuan, Shuofeng, Liu, Hang, Mok, Bobo Wing-Yee, Chen, Bohao, Wang, Pui, Poon, Vincent Kwok-Man, Chu, Hin, Chan, Chris Chung-Sing, Tsang, Jessica Oi-Ling, Chan, Chris Chun-Yiu, Au, Ka-Kit, Man, Hiu-On, Lu, Lu, To, Kelvin Kai-Wang, Chen, Honglin, Yuen, Kwok-Yung, Dang, Shangyu, Chen, Zhiwei
Published in Nature communications (23.06.2022)
Published in Nature communications (23.06.2022)
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Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters
Lee, Andrew Chak-Yiu, Zhang, Anna Jinxia, Chan, Jasper Fuk-Woo, Li, Can, Fan, Zhimeng, Liu, Feifei, Chen, Yanxia, Liang, Ronghui, Sridhar, Siddharth, Cai, Jian-Piao, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, To, Kelvin Kai-Wang, Yuan, Shuofeng, Zhou, Jie, Chu, Hin, Yuen, Kwok-Yung
Published in Cell Reports Medicine (20.10.2020)
Published in Cell Reports Medicine (20.10.2020)
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Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infection
Ye, Zi-Wei, Yuan, Shuofeng, Chan, Jasper Fuk-Woo, Zhang, Anna Jinxia, Yu, Ching-Yun, Ong, Chon Phin, Yang, Dong, Chan, Chris Chun-Yiu, Tang, Kaiming, Cao, Jianli, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Cai, Jian-Piao, Chu, Hin, Yuen, Kwok-Yung, Jin, Dong-Yan
Published in Emerging microbes & infections (01.01.2021)
Published in Emerging microbes & infections (01.01.2021)
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The spike receptor-binding motif G496S substitution determines the replication fitness of SARS-CoV-2 Omicron sublineage
Liang, Ronghui, Ye, Zi-Wei, Ong, Chon Phin, Qin, Zhenzhi, Xie, Yubin, Fan, Yilan, Tang, Kaiming, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Yang, Xiaomeng, Cao, Hehe, Wang, Kun, Sun, Haoran, Hu, Bodan, Cai, Jian-Piao, Luo, Cuiting, Chik, Kenn Ka-Heng, Chu, Hin, Zheng, Yi, Yuen, Kwok-Yung, Chan, Jasper Fuk-Woo, Jin, Dong-Yan, Yuan, Shuofeng
Published in Emerging microbes & infections (31.12.2022)
Published in Emerging microbes & infections (31.12.2022)
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A molecularly engineered, broad-spectrum anti-coronavirus lectin inhibits SARS-CoV-2 and MERS-CoV infection in vivo
Chan, Jasper Fuk-Woo, Oh, Yoo Jin, Yuan, Shuofeng, Chu, Hin, Yeung, Man-Lung, Canena, Daniel, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Chan, Chris Chun-Yiu, Zhang, Anna Jinxia, Cai, Jian-Piao, Ye, Zi-Wei, Wen, Lei, Yuen, Terrence Tsz-Tai, Chik, Kenn Ka-Heng, Shuai, Huiping, Wang, Yixin, Hou, Yuxin, Luo, Cuiting, Chan, Wan-Mui, Qin, Zhenzhi, Sit, Ko-Yung, Au, Wing-Kuk, Legendre, Maureen, Zhu, Rong, Hain, Lisa, Seferovic, Hannah, Tampé, Robert, To, Kelvin Kai-Wang, Chan, Kwok-Hung, Thomas, Dafydd Gareth, Klausberger, Miriam, Xu, Cheng, Moon, James J, Stadlmann, Johannes, Penninger, Josef M, Oostenbrink, Chris, Hinterdorfer, Peter, Yuen, Kwok-Yung, Markovitz, David M
Published in Cell reports. Medicine (18.10.2022)
Published in Cell reports. Medicine (18.10.2022)
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P21-activated kinase 1 (PAK1)-mediated cytoskeleton rearrangement promotes SARS-CoV-2 entry and ACE2 autophagic degradation
Liu, Ming, Lu, Bingtai, Li, Yue, Yuan, Shuofeng, Zhuang, Zhen, Li, Guangyu, Wang, Dong, Ma, Liuheyi, Zhu, Jianheng, Zhao, Jinglu, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Chik, Kenn Ka-Heng, Zhao, Zhiyao, Xian, Huifang, Zhao, Jingxian, Zhao, Jincun, Chan, Jasper Fuk-Woo, Zhang, Yuxia
Published in Signal transduction and targeted therapy (09.10.2023)
Published in Signal transduction and targeted therapy (09.10.2023)
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A novel linker-immunodominant site (LIS) vaccine targeting the SARS-CoV-2 spike protein protects against severe COVID-19 in Syrian hamsters
Zhang, Bao-Zhong, Wang, Xiaolei, Yuan, Shuofeng, Li, Wenjun, Dou, Ying, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Cai, Jian-Piao, Chik, Kenn KaHeng, Tang, Kaiming, Chan, Chris Chun-Yiu, Hu, Ye-Fan, Hu, Jing-Chu, Badea, Smaranda Ruxandra, Gong, Hua-Rui, Lin, Xuansheng, Chu, Hin, Li, Xuechen, To, Kelvin Kai-Wang, Liu, Li, Chen, Zhiwei, Hung, Ivan Fan-Ngai, Yuen, Kwok Yung, Chan, Jasper Fuk-Woo, Huang, Jian-Dong
Published in Emerging microbes & infections (01.01.2021)
Published in Emerging microbes & infections (01.01.2021)
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Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs
Chan, Jasper Fuk-Woo, Yip, Cyril Chik-Yan, Tsang, Jessica Oi-Ling, Tee, Kah-Meng, Cai, Jian-Piao, Chik, Kenn Ka-Heng, Zhu, Zheng, Chan, Chris Chung-Sing, Choi, Garnet Kwan-Yue, Sridhar, Siddharth, Zhang, Anna Jinxia, Lu, Gang, Chiu, Kin, Lo, Amy Cheuk-Yin, Tsao, Sai-Wah, Kok, Kin-Hang, Jin, Dong-Yan, Chan, Kwok-Hung, Yuen, Kwok-Yung
Published in Emerging microbes & infections (24.08.2016)
Published in Emerging microbes & infections (24.08.2016)
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An H5N1-based matrix protein 2 ectodomain tetrameric peptide vaccine provides cross-protection against lethal infection with H7N9 influenza virus
Leung, Ho-Chuen, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Zhao, Han-Jun, Cheung, Chung-Yan, Ng, Fai, Huang, Jian-Dong, Zheng, Bo-Jian
Published in Emerging microbes & infections (01.04.2015)
Published in Emerging microbes & infections (01.04.2015)
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SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target
Yuan, Shuofeng, Chu, Hin, Chan, Jasper Fuk-Woo, Ye, Zi-Wei, Wen, Lei, Yan, Bingpeng, Lai, Pok-Man, Tee, Kah-Meng, Huang, Jingjing, Chen, Dongdong, Li, Cun, Zhao, Xiaoyu, Yang, Dong, Chiu, Man Chun, Yip, Cyril, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Sze, Kong-Hung, Zhou, Jie, Chan, Ivy Hau-Yee, Kok, Kin-Hang, To, Kelvin Kai-Wang, Kao, Richard Yi-Tsun, Lau, Johnson Yiu-Nam, Jin, Dong-Yan, Perlman, Stanley, Yuen, Kwok-Yung
Published in Nature Communications (10.01.2019)
Published in Nature Communications (10.01.2019)
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