Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells
Guo, Jessie Yanxiang, Teng, Xin, Laddha, Saurabh V, Ma, Sirui, Van Nostrand, Stephen C, Yang, Yang, Khor, Sinan, Chan, Chang S, Rabinowitz, Joshua D, White, Eileen
Published in Genes & development (01.08.2016)
Published in Genes & development (01.08.2016)
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Mutational landscape of the essential autophagy gene BECN1 in human cancers
Laddha, Saurabh V, Ganesan, Shridar, Chan, Chang S, White, Eileen
Published in Molecular cancer research (01.04.2014)
Published in Molecular cancer research (01.04.2014)
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Autophagy is required for glucose homeostasis and lung tumor maintenance
Karsli-Uzunbas, Gizem, Guo, Jessie Yanxiang, Price, Sandy, Teng, Xin, Laddha, Saurabh V, Khor, Sinan, Kalaany, Nada Y, Jacks, Tyler, Chan, Chang S, Rabinowitz, Joshua D, White, Eileen
Published in Cancer discovery (01.08.2014)
Published in Cancer discovery (01.08.2014)
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ATRX, DAXX or MEN1 mutant pancreatic neuroendocrine tumors are a distinct alpha-cell signature subgroup
Chan, Chang S, Laddha, Saurabh V, Lewis, Peter W, Koletsky, Matthew S, Robzyk, Kenneth, Da Silva, Edaise, Torres, Paula J, Untch, Brian R, Li, Janet, Bose, Promita, Chan, Timothy A, Klimstra, David S, Allis, C David, Tang, Laura H
Published in Nature communications (12.10.2018)
Published in Nature communications (12.10.2018)
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The Genomic Landscape of Renal Oncocytoma Identifies a Metabolic Barrier to Tumorigenesis
Joshi, Shilpy, Tolkunov, Denis, Aviv, Hana, Hakimi, Abraham A., Yao, Ming, Hsieh, James J., Ganesan, Shridar, Chan, Chang S., White, Eileen
Published in Cell reports (Cambridge) (01.12.2015)
Published in Cell reports (Cambridge) (01.12.2015)
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Negative Regulation of Tumor Suppressor p53 by MicroRNA miR-504
Hu, Wenwei, Chan, Chang S., Wu, Rui, Zhang, Cen, Sun, Yvonne, Song, Jun S., Tang, Laura H., Levine, Arnold J., Feng, Zhaohui
Published in Molecular cell (11.06.2010)
Published in Molecular cell (11.06.2010)
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Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression
Choi, Soyoung, Wang, Dunrui, Chen, Xiang, Tang, Laura H, Verma, Akanksha, Chen, Zhengming, Kim, Bu Jung, Selesner, Leigh, Robzyk, Kenneth, Zhang, George, Pang, Sharon, Han, Teng, Chan, Chang S, Fahey, 3rd, Thomas J, Elemento, Olivier, Du, Yi-Chieh Nancy
Published in Molecular cancer (09.05.2019)
Published in Molecular cancer (09.05.2019)
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Clinical Actionability of Comprehensive Genomic Profiling for Management of Rare or Refractory Cancers
Hirshfield, Kim M., Tolkunov, Denis, Zhong, Hua, Ali, Siraj M., Stein, Mark N., Murphy, Susan, Vig, Hetal, Vazquez, Alexei, Glod, John, Moss, Rebecca A., Belyi, Vladimir, Chan, Chang S., Chen, Suzie, Goodell, Lauri, Foran, David, Yelensky, Roman, Palma, Norma A., Sun, James X., Miller, Vincent A., Stephens, Philip J., Ross, Jeffrey S., Kaufman, Howard, Poplin, Elizabeth, Mehnert, Janice, Tan, Antoinette R., Bertino, Joseph R., Aisner, Joseph, DiPaola, Robert S., Rodriguez‐Rodriguez, Lorna, Ganesan, Shridar
Published in The oncologist (Dayton, Ohio) (01.11.2016)
Published in The oncologist (Dayton, Ohio) (01.11.2016)
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The Role of the p53 Protein in Stem-Cell Biology and Epigenetic Regulation
Levine, Arnold J, Puzio-Kuter, Anna M, Chan, Chang S, Hainaut, Pierre
Published in Cold Spring Harbor perspectives in medicine (01.09.2016)
Published in Cold Spring Harbor perspectives in medicine (01.09.2016)
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Why are there hotspot mutations in the TP53 gene in human cancers?
Baugh, Evan H, Ke, Hua, Levine, Arnold J, Bonneau, Richard A, Chan, Chang S
Published in Cell death and differentiation (01.01.2018)
Published in Cell death and differentiation (01.01.2018)
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Integrated metabolic and genetic analysis reveals distinct features of human differentiated thyroid cancer
Cararo Lopes, Eduardo, Sawant, Akshada, Moore, Dirk, Ke, Hua, Shi, Fuqian, Laddha, Saurabh, Chen, Ying, Sharma, Anchal, Naumann, Jake, Guo, Jessie Yanxiang, Gomez, Maria, Ibrahim, Maria, Smith, Tracey L., Riedlinger, Gregory M., Lattime, Edmund C., Trooskin, Stanley, Ganesan, Shridar, Su, Xiaoyang, Pasqualini, Renata, Arap, Wadih, De, Subhajyoti, Chan, Chang S., White, Eileen
Published in Clinical and translational medicine (01.06.2023)
Published in Clinical and translational medicine (01.06.2023)
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Whole-genome sequencing analysis of phenotypic heterogeneity and anticipation in Li–Fraumeni cancer predisposition syndrome
Ariffin, Hany, Hainaut, Pierre, Puzio-Kuter, Anna, Choong, Soo Sin, Chan, Adelyne Sue Li, Tolkunov, Denis, Rajagopal, Gunaretnam, Kang, Wenfeng, Lim, Leon Li Wen, Krishnan, Shekhar, Chen, Kok-Siong, Achatz, Maria Isabel, Karsa, Mawar, Shamsani, Jannah, Levine, Arnold J., Chan, Chang S.
Published in Proceedings of the National Academy of Sciences - PNAS (28.10.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (28.10.2014)
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Revealing posttranscriptional regulatory elements through network-level conservation
Chan, Chang S, Elemento, Olivier, Tavazoie, Saeed
Published in PLoS computational biology (01.12.2005)
Published in PLoS computational biology (01.12.2005)
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Medulloblastomas Initiated by Homologous Recombination Defects in Mice
Lu, Huimei, Wang, Yuan, Chaudhary, Shipra, Balaga, Varshita, Ke, Hua, Shi, Fuqian, Liu, Jingmei, Huo, Yangyin, Romanienko, Peter J., Xia, Bing, De, Subhajyoti, Chan, Chang S., Shen, Zhiyuan
Published in The American journal of pathology (19.08.2024)
Published in The American journal of pathology (19.08.2024)
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Integrative Genomic Characterization Identifies Molecular Subtypes of Lung Carcinoids
Laddha, Saurabh V, da Silva, Edaise M, Robzyk, Kenneth, Untch, Brian R, Ke, Hua, Rekhtman, Natasha, Poirier, John T, Travis, William D, Tang, Laura H, Chan, Chang S
Published in Cancer research (Chicago, Ill.) (01.09.2019)
Published in Cancer research (Chicago, Ill.) (01.09.2019)
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Therapy-induced APOBEC3A drives evolution of persistent cancer cells
Isozaki, Hideko, Sakhtemani, Ramin, Abbasi, Ammal, Nikpour, Naveed, Stanzione, Marcello, Oh, Sunwoo, Langenbucher, Adam, Monroe, Susanna, Su, Wenjia, Cabanos, Heidie Frisco, Siddiqui, Faria M, Phan, Nicole, Jalili, Pégah, Timonina, Daria, Bilton, Samantha, Gomez-Caraballo, Maria, Archibald, Hannah L, Nangia, Varuna, Dionne, Kristin, Riley, Amanda, Lawlor, Matthew, Banwait, Mandeep Kaur, Cobb, Rosemary G, Zou, Lee, Dyson, Nicholas J, Ott, Christopher J, Benes, Cyril, Getz, Gad, Chan, Chang S, Shaw, Alice T, Gainor, Justin F, Lin, Jessica J, Sequist, Lecia V, Piotrowska, Zofia, Yeap, Beow Y, Engelman, Jeffrey A, Lee, Jake June-Koo, Maruvka, Yosef E, Buisson, Rémi, Lawrence, Michael S, Hata, Aaron N
Published in Nature (London) (10.08.2023)
Published in Nature (London) (10.08.2023)
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Truncated FGFR2 is a clinically actionable oncogene in multiple cancers
Zingg, Daniel, Bhin, Jinhyuk, Yemelyanenko, Julia, Kas, Sjors M., Rolfs, Frank, Lutz, Catrin, Lee, Jessica K., Klarenbeek, Sjoerd, Silverman, Ian M., Annunziato, Stefano, Chan, Chang S., Piersma, Sander R., Eijkman, Timo, Badoux, Madelon, Gogola, Ewa, Siteur, Bjørn, Sprengers, Justin, de Klein, Bim, de Goeij-de Haas, Richard R., Riedlinger, Gregory M., Ke, Hua, Madison, Russell, Drenth, Anne Paulien, van der Burg, Eline, Schut, Eva, Henneman, Linda, van Miltenburg, Martine H., Proost, Natalie, Zhen, Huiling, Wientjens, Ellen, de Bruijn, Roebi, de Ruiter, Julian R., Boon, Ute, de Korte-Grimmerink, Renske, van Gerwen, Bastiaan, Féliz, Luis, Abou-Alfa, Ghassan K., Ross, Jeffrey S., van de Ven, Marieke, Rottenberg, Sven, Cuppen, Edwin, Chessex, Anne Vaslin, Ali, Siraj M., Burn, Timothy C., Jimenez, Connie R., Ganesan, Shridar, Wessels, Lodewyk F. A., Jonkers, Jos
Published in Nature (London) (18.08.2022)
Published in Nature (London) (18.08.2022)
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Tumor suppressor p53 negatively regulates glycolysis stimulated by hypoxia through its target RRAD
Zhang, Cen, Liu, Juan, Wu, Rui, Liang, Yingjian, Lin, Meihua, Liu, Jia, Chan, Chang S, Hu, Wenwei, Feng, Zhaohui
Published in Oncotarget (30.07.2014)
Published in Oncotarget (30.07.2014)
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SMAD4 is critical in suppression of BRAF-V600E serrated tumorigenesis
Tong, Kevin, Kothari, Om A, Haro, Katherine S, Panda, Anshuman, Bandari, Manisha M, Carrick, Jillian N, Hur, Joseph J, Zhang, Lanjing, Chan, Chang S, Xing, Jinchuan, Gatza, Michael L, Ganesan, Shridar, Verzi, Michael P
Published in Oncogene (14.10.2021)
Published in Oncogene (14.10.2021)
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