A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening
Yan, Helen H.N., Siu, Hoi Cheong, Law, Simon, Ho, Siu Lun, Yue, Sarah S.K., Tsui, Wai Yin, Chan, Dessy, Chan, April S., Ma, Stephanie, Lam, Ka On, Bartfeld, Sina, Man, Alice H.Y., Lee, Bernard C.H., Chan, Annie S.Y., Wong, Jason W.H., Cheng, Priscilla S.W., Chan, Anthony K.W., Zhang, Jiangwen, Shi, Jue, Fan, Xiaodan, Kwong, Dora L.W., Mak, Tak W., Yuen, Siu Tsan, Clevers, Hans, Leung, Suet Yi
Published in Cell stem cell (06.12.2018)
Published in Cell stem cell (06.12.2018)
Get full text
Journal Article
Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer
Wang, Kai, Yuen, Siu Tsan, Xu, Jiangchun, Lee, Siu Po, Yan, Helen H N, Shi, Stephanie T, Siu, Hoi Cheong, Deng, Shibing, Chu, Kent Man, Law, Simon, Chan, Kok Hoe, Chan, Annie S Y, Tsui, Wai Yin, Ho, Siu Lun, Chan, Anthony K W, Man, Jonathan L K, Foglizzo, Valentina, Ng, Man Kin, Chan, April S, Ching, Yick Pang, Cheng, Grace H W, Xie, Tao, Fernandez, Julio, Li, Vivian S W, Clevers, Hans, Rejto, Paul A, Mao, Mao, Leung, Suet Yi
Published in Nature genetics (01.06.2014)
Published in Nature genetics (01.06.2014)
Get full text
Journal Article
Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer
Wang, Kai, Kan, Junsuo, Yuen, Siu Tsan, Shi, Stephanie T, Chu, Kent Man, Law, Simon, Chan, Tsun Leung, Kan, Zhengyan, Chan, Annie S Y, Tsui, Wai Yin, Lee, Siu Po, Ho, Siu Lun, Chan, Anthony K W, Cheng, Grace H W, Roberts, Peter C, Rejto, Paul A, Gibson, Neil W, Pocalyko, David J, Mao, Mao, Xu, Jiangchun, Leung, Suet Yi
Published in Nature genetics (01.12.2011)
Published in Nature genetics (01.12.2011)
Get full text
Journal Article
RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation
Yan, Helen H N, Lai, Jeffrey C W, Ho, Siu Lun, Leung, Wai Keung, Law, Wai Lun, Lee, Janet F Y, Chan, Anthony K W, Tsui, Wai Yin, Chan, Annie S Y, Lee, Bernard C H, Yue, Sarah S K, Man, Alice H Y, Clevers, Hans, Yuen, Siu Tsan, Leung, Suet Yi
Published in Gut (01.09.2017)
Published in Gut (01.09.2017)
Get full text
Journal Article
Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database
Thompson, Bryony A, Spurdle, Amanda B, Plazzer, John-Paul, Greenblatt, Marc S, Akagi, Kiwamu, Al-Mulla, Fahd, Bapat, Bharati, Bernstein, Inge, Capellá, Gabriel, den Dunnen, Johan T, du Sart, Desiree, Fabre, Aurelie, Farrell, Michael P, Farrington, Susan M, Frayling, Ian M, Frebourg, Thierry, Goldgar, David E, Heinen, Christopher D, Holinski-Feder, Elke, Kohonen-Corish, Maija, Robinson, Kristina Lagerstedt, Leung, Suet Yi, Martins, Alexandra, Moller, Pal, Morak, Monika, Nystrom, Minna, Peltomaki, Paivi, Pineda, Marta, Qi, Ming, Ramesar, Rajkumar, Rasmussen, Lene Juel, Royer-Pokora, Brigitte, Scott, Rodney J, Sijmons, Rolf, Tavtigian, Sean V, Tops, Carli M, Weber, Thomas, Wijnen, Juul, Woods, Michael O, Macrae, Finlay, Genuardi, Maurizio
Published in Nature genetics (01.02.2014)
Published in Nature genetics (01.02.2014)
Get full text
Journal Article
Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles
Yan, Helen H N, Siu, Hoi Cheong, Ho, Siu Lun, Yue, Sarah S K, Gao, Yang, Tsui, Wai Yin, Chan, Dessy, Chan, April S, Wong, Jason W H, Man, Alice H Y, Lee, Bernard C H, Chan, Annie S Y, Chan, Anthony K W, Hui, Ho Sang, Cheung, Arthur K L, Law, Wai Lun, Lo, Oswens S H, Yuen, Siu Tsan, Clevers, Hans, Leung, Suet Yi
Published in Gut (01.12.2020)
Published in Gut (01.12.2020)
Get full text
Journal Article
Mutational landscape of normal epithelial cells in Lynch Syndrome patients
Lee, Bernard C. H., Robinson, Philip S., Coorens, Tim H. H., Yan, Helen H. N., Olafsson, Sigurgeir, Lee-Six, Henry, Sanders, Mathijs A., Siu, Hoi Cheong, Hewinson, James, Yue, Sarah S. K., Tsui, Wai Yin, Chan, Annie S. Y., Chan, Anthony K. W., Ho, Siu Lun, Campbell, Peter J., Martincorena, Inigo, Buczacki, Simon J. A., Yuen, Siu Tsan, Leung, Suet Yi, Stratton, Michael R.
Published in Nature communications (17.05.2022)
Published in Nature communications (17.05.2022)
Get full text
Journal Article