A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies
Lehne, Benjamin, Drong, Alexander W, Loh, Marie, Zhang, Weihua, Scott, William R, Tan, Sian-Tsung, Afzal, Uzma, Scott, James, Jarvelin, Marjo-Riitta, Elliott, Paul, McCarthy, Mark I, Kooner, Jaspal S, Chambers, John C
Published in Genome Biology (15.02.2015)
Published in Genome Biology (15.02.2015)
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Journal Article
Liver Function and Risk of Type 2 Diabetes: Bidirectional Mendelian Randomization Study
De Silva, N Maneka G, Borges, Maria Carolina, Hingorani, Aroon D, Engmann, Jorgen, Shah, Tina, Zhang, Xiaoshuai, Luan, Jian'an, Langenberg, Claudia, Wong, Andrew, Kuh, Diana, Chambers, John C, Zhang, Weihua, Jarvelin, Marjo-Ritta, Sebert, Sylvain, Auvinen, Juha, Gaunt, Tom R, Lawlor, Deborah A
Published in Diabetes (New York, N.Y.) (01.08.2019)
Published in Diabetes (New York, N.Y.) (01.08.2019)
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Journal Article
Arrhythmogenic cardiomyopathy: etiology, diagnosis, and treatment
Sen-Chowdhry, Srijita, Morgan, Robert D, Chambers, John C, McKenna, William J
Published in Annual review of medicine (01.01.2010)
Published in Annual review of medicine (01.01.2010)
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Journal Article
Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics
Tynkkynen, Tuulia, Wang, Qin, Ekholm, Jussi, Anufrieva, Olga, Ohukainen, Pauli, Vepsäläinen, Jouko, Männikkö, Minna, Keinänen-Kiukaanniemi, Sirkka, Holmes, Michael V, Goodwin, Matthew, Ring, Susan, Chambers, John C, Kooner, Jaspal, Järvelin, Marjo-Riitta, Kettunen, Johannes, Hill, Michael, Davey Smith, George, Ala-Korpela, Mika
Published in International journal of epidemiology (01.06.2019)
Published in International journal of epidemiology (01.06.2019)
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Journal Article
Contribution of lower physical activity levels to higher risk of insulin resistance and associated metabolic disturbances in South Asians compared to Europeans
Afaq, Saima, Kooner, Angad S, Loh, Marie, Kooner, Jaspal S, Chambers, John C
Published in PloS one (07.05.2019)
Published in PloS one (07.05.2019)
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Journal Article
Smokeless and combustible tobacco use among 148,944 South Asian adults: a cross-sectional study of South Asia Biobank
Xie, Wubin, Mridha, Malay Kanti, Gupta, Anaya, Kusuma, Dian, Butt, Awais Muhammad, Hasan, Mehedi, Brage, Soren, Loh, Marie, Khawaja, Khadija Irfan, Pradeepa, Rajendra, Jha, Vinita, Kasturiratne, Anuradhani, Katulanda, Prasad, Anjana, Ranjit Mohan, Chambers, John C
Published in BMC public health (09.12.2023)
Published in BMC public health (09.12.2023)
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Journal Article
A replication study of GWAS-derived lipid genes in Asian Indians: the chromosomal region 11q23.3 harbors loci contributing to triglycerides
Braun, Timothy R, Been, Latonya F, Singhal, Akhil, Worsham, Jacob, Ralhan, Sarju, Wander, Gurpreet S, Chambers, John C, Kooner, Jaspal S, Aston, Christopher E, Sanghera, Dharambir K
Published in PloS one (18.05.2012)
Published in PloS one (18.05.2012)
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Journal Article
Common Genetic Variation Near Melatonin Receptor MTNR1B Contributes to Raised Plasma Glucose and Increased Risk of Type 2 Diabetes Among Indian Asians and European Caucasians
CHAMBERS, John C, WEIHUA ZHANG, SCOTT, James, ELLIOTT, Paul, KOONER, Jaspal S, ZABANEH, Delilah, SEHMI, Joban, JAIN, Piyush, MCCARTHY, Mark I, FROGUEL, Philippe, RUOKONEN, Aimo, BALDING, David, JARVELIN, Marjo-Riitta
Published in Diabetes (New York, N.Y.) (01.11.2009)
Published in Diabetes (New York, N.Y.) (01.11.2009)
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Journal Article
The South Asian genome
Chambers, John C, Abbott, James, Zhang, Weihua, Turro, Ernest, Scott, William R, Tan, Sian-Tsung, Afzal, Uzma, Afaq, Saima, Loh, Marie, Lehne, Benjamin, O'Reilly, Paul, Gaulton, Kyle J, Pearson, Richard D, Li, Xinzhong, Lavery, Anita, Vandrovcova, Jana, Wass, Mark N, Miller, Kathryn, Sehmi, Joban, Oozageer, Laticia, Kooner, Ishminder K, Al-Hussaini, Abtehale, Mills, Rebecca, Grewal, Jagvir, Panoulas, Vasileios, Lewin, Alexandra M, Northwood, Korrinne, Wander, Gurpreet S, Geoghegan, Frank, Li, Yingrui, Wang, Jun, Aitman, Timothy J, McCarthy, Mark I, Scott, James, Butcher, Sarah, Elliott, Paul, Kooner, Jaspal S
Published in PloS one (12.08.2014)
Published in PloS one (12.08.2014)
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Journal Article
Comparing methods for performing trans-ethnic meta-analysis of genome-wide association studies
Wang, Xu, Chua, Hui-Xiang, Chen, Peng, Ong, Rick Twee-Hee, Sim, Xueling, Zhang, Weihua, Takeuchi, Fumihiko, Liu, Xuanyao, Khor, Chiea-Chuen, Tay, Wan-Ting, Cheng, Ching-Yu, Suo, Chen, Liu, Jianjun, Aung, Tin, Chia, Kee-Seng, Kooner, Jaspal S, Chambers, John C, Wong, Tien-Yin, Tai, E-Shyong, Kato, Norihiro, Teo, Yik-Ying
Published in Human molecular genetics (01.06.2013)
Published in Human molecular genetics (01.06.2013)
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Journal Article
Investigation of Genetic Variation Underlying Central Obesity amongst South Asians
Scott, William R, Zhang, Weihua, Loh, Marie, Tan, Sian-Tsung, Lehne, Benjamin, Afzal, Uzma, Peralta, Juan, Saxena, Richa, Ralhan, Sarju, Wander, Gurpreet S, Bozaoglu, Kiymet, Sanghera, Dharambir K, Elliott, Paul, Scott, James, Chambers, John C, Kooner, Jaspal S
Published in PloS one (19.05.2016)
Published in PloS one (19.05.2016)
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Journal Article
The iHealth-T2D study: a cluster randomised trial for the prevention of type 2 diabetes amongst South Asians with central obesity and prediabetes-a statistical analysis plan
Muilwijk, Mirthe, Loh, Marie, Mahmood, Sara, Palaniswamy, Saranya, Siddiqui, Samreen, Silva, Wnurinham, Frost, Gary S, Gage, Heather M, Jarvelin, Marjo-Riitta, Rannan-Eliya, Ravindra P, Ahmad, Sajjad, Jha, Sujeet, Kasturiratne, Anuradhani, Katulanda, Prasad, Khawaja, Khadija I, Kooner, Jaspal S, Wickremasinghe, Ananda R, van Valkengoed, Irene G M, Chambers, John C
Published in Current controlled trials in cardiovascular medicine (06.09.2022)
Published in Current controlled trials in cardiovascular medicine (06.09.2022)
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Journal Article
Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci
Paul, Dirk S, Albers, Cornelis A, Rendon, Augusto, Voss, Katrin, Stephens, Jonathan, van der Harst, Pim, Chambers, John C, Soranzo, Nicole, Ouwehand, Willem H, Deloukas, Panos
Published in Genome research (01.07.2013)
Published in Genome research (01.07.2013)
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Journal Article
Food environments and obesity: A geospatial analysis of the South Asia Biobank, income and sex inequalities
Atanasova, Petya, Kusuma, Dian, Pineda, Elisa, Anjana, Ranjit Mohan, De Silva, Laksara, Hanif, Abu A.M., Hasan, Mehedi, Hossain, Md Mokbul, Indrawansa, Susantha, Jayamanne, Deepal, Jha, Sujeet, Kasturiratne, Anuradhani, Katulanda, Prasad, Khawaja, Khadija I., Kumarendran, Balachandran, Mridha, Malay K., Rajakaruna, Vindya, Chambers, John C., Frost, Gary, Sassi, Franco, Miraldo, Marisa
Published in SSM - population health (01.03.2022)
Published in SSM - population health (01.03.2022)
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Journal Article
Translational Perspective on Epigenetics in Cardiovascular Disease
van der Harst, Pim, de Windt, Leon J., Chambers, John C.
Published in Journal of the American College of Cardiology (01.08.2017)
Published in Journal of the American College of Cardiology (01.08.2017)
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Journal Article
A genomic mutational constraint map using variation in 76,156 human genomes
Chen, Siwei, Francioli, Laurent C., Goodrich, Julia K., Collins, Ryan L., Kanai, Masahiro, Wang, Qingbo, Alföldi, Jessica, Watts, Nicholas A., Vittal, Christopher, Gauthier, Laura D., Poterba, Timothy, Wilson, Michael W., Tarasova, Yekaterina, Phu, William, Grant, Riley, Yohannes, Mary T., Koenig, Zan, Farjoun, Yossi, Banks, Eric, Donnelly, Stacey, Gabriel, Stacey, Gupta, Namrata, Ferriera, Steven, Tolonen, Charlotte, Novod, Sam, Bergelson, Louis, Roazen, David, Ruano-Rubio, Valentin, Covarrubias, Miguel, Llanwarne, Christopher, Petrillo, Nikelle, Wade, Gordon, Jeandet, Thibault, Munshi, Ruchi, Tibbetts, Kathleen, O’Donnell-Luria, Anne, Solomonson, Matthew, Seed, Cotton, Martin, Alicia R., Talkowski, Michael E., Rehm, Heidi L., Daly, Mark J., Tiao, Grace, Neale, Benjamin M., MacArthur, Daniel G., Karczewski, Konrad J.
Published in Nature (London) (04.01.2024)
Published in Nature (London) (04.01.2024)
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Journal Article
Plasma homocysteine concentrations and risk of coronary heart disease in UK Indian Asian and European men
Chambers, John C, Obeid, Omar A, Refsum, Helga, Ueland, Per, Hackett, David, Hooper, James, Turner, Rebecca M, Thompson, Slmon G, Kooner, Jaspal S
Published in The Lancet (British edition) (12.02.2000)
Published in The Lancet (British edition) (12.02.2000)
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Journal Article
The distinct relationships of carotid plaque disease and carotid intima-media thickness with left ventricular function
Chahal, Navtej S, Lim, Tiong K, Jain, Piyush, Chambers, John C, Kooner, Jaspal S, Senior, Roxy
Published in Journal of the American Society of Echocardiography (01.12.2010)
Published in Journal of the American Society of Echocardiography (01.12.2010)
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Journal Article
Does subclinical atherosclerosis burden identify the increased risk of cardiovascular disease mortality among United Kingdom Indian Asians? A population study
Chahal, Navtej S., MBBS, Lim, Tiong K., MBBS, Jain, Piyush, MBBS, Chambers, John C., MBBS, Kooner, Jaspal S., MBBS, Senior, Roxy, MBBS
Published in The American heart journal (01.09.2011)
Published in The American heart journal (01.09.2011)
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