Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters
Yuan, Shuofeng, Wang, Runming, Chan, Jasper Fuk-Woo, Zhang, Anna Jinxia, Cheng, Tianfan, Chik, Kenn Ka-Heng, Ye, Zi-Wei, Wang, Suyu, Lee, Andrew Chak-Yiu, Jin, Lijian, Li, Hongyan, Jin, Dong-Yan, Yuen, Kwok-Yung, Sun, Hongzhe
Published in Nature microbiology (01.11.2020)
Published in Nature microbiology (01.11.2020)
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Characterization of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein
Wang, Pui, Lau, Siu-Ying, Deng, Shaofeng, Chen, Pin, Mok, Bobo Wing-Yee, Zhang, Anna Jinxia, Lee, Andrew Chak-Yiu, Chan, Kwok-Hung, Tam, Rachel Chun-Yee, Xu, Haoran, Zhou, Runhong, Song, Wenjun, Liu, Li, To, Kelvin Kai-Wang, Chan, Jasper Fuk-Woo, Chen, Zhiwei, Yuen, Kwok-Yung, Chen, Honglin
Published in Nature communications (13.05.2021)
Published in Nature communications (13.05.2021)
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SARS-CoV-2 infects human neural progenitor cells and brain organoids
Zhang, Bao-Zhong, Chu, Hin, Han, Shuo, Shuai, Huiping, Deng, Jian, Hu, Ye-fan, Gong, Hua-rui, Lee, Andrew Chak-Yiu, Zou, Zijiao, Yau, Thomas, Wu, Wutian, Hung, Ivan Fan-Ngai, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung, Huang, Jian-Dong
Published in Cell research (01.10.2020)
Published in Cell research (01.10.2020)
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Simulation of the Clinical and Pathological Manifestations of Coronavirus Disease 2019 (COVID-19) in a Golden Syrian Hamster Model: Implications for Disease Pathogenesis and Transmissibility
Chan, Jasper Fuk-Woo, Zhang, Anna Jinxia, Yuan, Shuofeng, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Lee, Andrew Chak-Yiu, Chan, Wan-Mui, Fan, Zhimeng, Tsoi, Hoi-Wah, Wen, Lei, Liang, Ronghui, Cao, Jianli, Chen, Yanxia, Tang, Kaiming, Luo, Cuiting, Cai, Jian-Piao, Kok, Kin-Hang, Chu, Hin, Chan, Kwok-Hung, Sridhar, Siddharth, Chen, Zhiwei, Chen, Honglin, To, Kelvin Kai-Wang, Yuen, Kwok-Yung
Published in Clinical Infectious Diseases (26.03.2020)
Published in Clinical Infectious Diseases (26.03.2020)
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Attenuated Interferon and Proinflammatory Response in SARS-CoV-2–Infected Human Dendritic Cells Is Associated With Viral Antagonism of STAT1 Phosphorylation
Yang, Dong, Chu, Hin, Hou, Yuxin, Chai, Yue, Shuai, Huiping, Lee, Andrew Chak-Yiu, Zhang, Xi, Wang, Yixin, Hu, Bingjie, Huang, Xiner, Yuen, Terrence Tsz-Tai, Cai, Jian-Piao, Zhou, Jie, Yuan, Shuofeng, Zhang, Anna Jinxia, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung
Published in The Journal of infectious diseases (04.08.2020)
Published in The Journal of infectious diseases (04.08.2020)
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Surgical Mask Partition Reduces the Risk of Noncontact Transmission in a Golden Syrian Hamster Model for Coronavirus Disease 2019 (COVID-19)
Chan, Jasper Fuk-Woo, Yuan, Shuofeng, Zhang, Anna Jinxia, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Lee, Andrew Chak-Yiu, Fan, Zhimeng, Li, Can, Liang, Ronghui, Cao, Jianli, Tang, Kaiming, Luo, Cuiting, Cheng, Vincent Chi-Chung, Cai, Jian-Piao, Chu, Hin, Chan, Kwok-Hung, To, Kelvin Kai-Wang, Sridhar, Siddharth, Yuen, Kwok-Yung
Published in Clinical infectious diseases (19.11.2020)
Published in Clinical infectious diseases (19.11.2020)
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Clofazimine broadly inhibits coronaviruses including SARS-CoV-2
Yuan, Shuofeng, Yin, Xin, Meng, Xiangzhi, Chan, Jasper Fuk-Woo, Ye, Zi-Wei, Riva, Laura, Pache, Lars, Chan, Chris Chun-Yiu, Lai, Pok-Man, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Lee, Andrew Chak-Yiu, Matsunaga, Naoko, Pu, Yuan, Yuen, Chun-Kit, Cao, Jianli, Liang, Ronghui, Tang, Kaiming, Sheng, Li, Du, Yushen, Xu, Wan, Lau, Chit-Ying, Sit, Ko-Yung, Au, Wing-Kuk, Wang, Runming, Zhang, Yu-Yuan, Tang, Yan-Dong, Clausen, Thomas Mandel, Pihl, Jessica, Oh, Juntaek, Sze, Kong-Hung, Zhang, Anna Jinxia, Chu, Hin, Kok, Kin-Hang, Wang, Dong, Cai, Xue-Hui, Esko, Jeffrey D., Hung, Ivan Fan-Ngai, Li, Ronald Adolphus, Chen, Honglin, Sun, Hongzhe, Jin, Dong-Yan, Sun, Ren, Chanda, Sumit K., Yuen, Kwok-Yung
Published in Nature (London) (20.05.2021)
Published in Nature (London) (20.05.2021)
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Severe Acute Respiratory Syndrome Coronavirus 2 Infects and Damages the Mature and Immature Olfactory Sensory Neurons of Hamsters
Zhang, Anna Jinxia, Lee, Andrew Chak-Yiu, Chu, Hin, Chan, Jasper Fuk-Woo, Fan, Zhimeng, Li, Can, Liu, Feifei, Chen, Yanxia, Yuan, Shuofeng, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Cai, Jian-Piao, Wu, Kenneth Lap-Kei, Sridhar, Siddharth, Chan, Ying-Shing, Yuen, Kwok-Yung
Published in Clinical infectious diseases (15.07.2021)
Published in Clinical infectious diseases (15.07.2021)
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Coinfection by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza A(H1N1)pdm09 Virus Enhances the Severity of Pneumonia in Golden Syrian Hamsters
Zhang, Anna Jinxia, Lee, Andrew Chak-Yiu, Chan, Jasper Fuk-Woo, Liu, Feifei, Li, Can, Chen, Yanxia, Chu, Hin, Lau, Siu-Ying, Wang, Pui, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Yuan, Shuofeng, To, Kelvin Kai-Wang, Chen, Honglin, Yuen, Kwok-Yung
Published in Clinical infectious diseases (15.06.2021)
Published in Clinical infectious diseases (15.06.2021)
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Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction
Lau, Siu-Ying, Wang, Pui, Mok, Bobo Wing-Yee, Zhang, Anna Jinxia, Chu, Hin, Lee, Andrew Chak-Yiu, Deng, Shaofeng, Chen, Pin, Chan, Kwok-Hung, Song, Wenjun, Chen, Zhiwei, To, Kelvin Kai-Wang, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung, Chen, Honglin
Published in Emerging microbes & infections (01.01.2020)
Published in Emerging microbes & infections (01.01.2020)
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Intradermal vaccination of live attenuated influenza vaccine protects mice against homologous and heterologous influenza challenges
Lee, Andrew Chak-Yiu, Zhang, Anna Jinxia, Li, Can, Chen, Yanxia, Liu, Feifei, Zhao, Yan, Chu, Hin, Fong, Carol Ho-Yan, Wang, Pui, Lau, Siu-Ying, To, Kelvin Kai-Wang, Chen, Honglin, Yuen, Kwok-Yung
Published in npj vaccines (04.08.2021)
Published in npj vaccines (04.08.2021)
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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection by Intranasal or Intratesticular Route Induces Testicular Damage
Li, Can, Ye, Zhanhong, Zhang, Anna Jin Xia, Chan, Jasper Fuk Woo, Song, Wenchen, Liu, Feifei, Chen, Yanxia, Kwan, Mike Yat Wah, Lee, Andrew Chak Yiu, Zhao, Yan, Wong, Bosco Ho Yin, Yip, Cyril Chik Yan, Cai, Jian Piao, Lung, David Christopher, Sridhar, Siddharth, Jin, Dongyan, Chu, Hin, To, Kelvin Kai Wang, Yuen, Kwok Yung
Published in Clinical infectious diseases (24.08.2022)
Published in Clinical infectious diseases (24.08.2022)
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An interferon-integrated mucosal vaccine provides pan-sarbecovirus protection in small animal models
Yuen, Chun-Kit, Wong, Wan-Man, Mak, Long-Fung, Lam, Joy-Yan, Cheung, Lok-Yi, Cheung, Derek Tsz-Yin, Ng, Yau-Yee, Lee, Andrew Chak-Yiu, Zhong, Nanshan, Yuen, Kwok-Yung, Kok, Kin-Hang
Published in Nature communications (24.10.2023)
Published in Nature communications (24.10.2023)
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Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters
Lee, Andrew Chak-Yiu, Zhang, Anna Jinxia, Chan, Jasper Fuk-Woo, Li, Can, Fan, Zhimeng, Liu, Feifei, Chen, Yanxia, Liang, Ronghui, Sridhar, Siddharth, Cai, Jian-Piao, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, To, Kelvin Kai-Wang, Yuan, Shuofeng, Zhou, Jie, Chu, Hin, Yuen, Kwok-Yung
Published in Cell Reports Medicine (20.10.2020)
Published in Cell Reports Medicine (20.10.2020)
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Olfactory Dysfunction in Coronavirus Disease 2019 Patients: Observational Cohort Study and Systematic Review
Chung, Tom Wai-Hin, Sridhar, Siddharth, Zhang, Anna Jinxia, Chan, Kwok-Hung, Li, Hang-Long, Wong, Fergus Kai-Chuen, Ng, Ming-Yen, Tsang, Raymond King-Yin, Lee, Andrew Chak-Yiu, Fan, Zhimeng, Ho, Ronnie Siu-Lun, Luk, Shiobhon Yiu, Kan, Wai-Kuen, Lam, Sonia Hiu-Yin, Wu, Alan Ka-Lun, Leung, Sau-Man, Chan, Wai-Ming, Ng, Pauline Yeung, To, Kelvin Kai-Wang, Cheng, Vincent Chi-Chung, Lung, Kwok-Cheung, Hung, Ivan Fan-Ngai, Yuen, Kwok-Yung
Published in Open Forum Infectious Diseases (01.06.2020)
Published in Open Forum Infectious Diseases (01.06.2020)
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Intranasal infection by SARS-CoV-2 Omicron variants can induce inflammatory brain damage in newly weaned hamsters
Li, Can, Song, Wenchen, Chan, Jasper Fuk-Woo, Chen, Yanxia, Liu, Feifei, Ye, Zhanhong, Lam, Alvin Hiu-Chung, Cai, Jianpiao, Lee, Andrew Chak-Yiu, Wong, Bosco Ho-Yin, Chu, Hin, Lung, David Christopher, Sridhar, Siddharth, Chen, Honglin, Zhang, Anna Jin-Xia, Yuen, Kwok-Yung
Published in Emerging microbes & infections (01.12.2023)
Published in Emerging microbes & infections (01.12.2023)
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STAT2-dependent restriction of Zika virus by human macrophages but not dendritic cells
Yang, Dong, Chu, Hin, Lu, Gang, Shuai, Huiping, Wang, Yixin, Hou, Yuxin, Zhang, Xi, Huang, Xiner, Hu, Bingjie, Chai, Yue, Yuen, Terrence Tsz-Tai, Zhao, Xiaoyu, Lee, Andrew Chak-Yiu, Ye, Ziwei, Li, Cun, Chik, Kenn Ka-Heng, Zhang, Anna Jinxia, Zhou, Jie, Yuan, Shuofeng, Chan, Jasper Fuk-Woo
Published in Emerging microbes & infections (01.01.2021)
Published in Emerging microbes & infections (01.01.2021)
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Repurposing of Miltefosine as an Adjuvant for Influenza Vaccine
Lu, Lu, Fong, Carol Ho-Yan, Zhang, Anna Jinxia, Wu, Wai-Lan, Li, Iris Can, Lee, Andrew Chak-Yiu, Dissanayake, Thrimendra Kaushika, Chen, Linlei, Hung, Ivan Fan-Ngai, Chan, Kwok-Hung, Chu, Hin, Kok, Kin-Hang, Yuen, Kwok-Yung, To, Kelvin Kai-Wang
Published in Vaccines (Basel) (11.12.2020)
Published in Vaccines (Basel) (11.12.2020)
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Middle East Respiratory Syndrome Coronavirus Efficiently Infects Human Primary T Lymphocytes and Activates the Extrinsic and Intrinsic Apoptosis Pathways
Chu, Hin, Zhou, Jie, Wong, Bosco Ho-Yin, Li, Cun, Chan, Jasper Fuk-Woo, Cheng, Zhong-Shan, Yang, Dong, Wang, Dong, Lee, Andrew Chak-Yiu, Li, Chuangen, Yeung, Man-Lung, Cai, Jian-Piao, Chan, Ivy Hau-Yee, Ho, Wai-Kuen, To, Kelvin Kai-Wang, Zheng, Bo-Jian, Yao, Yanfeng, Qin, Chuan, Yuen, Kwok-Yung
Published in The Journal of infectious diseases (15.03.2016)
Published in The Journal of infectious diseases (15.03.2016)
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TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation
Ho, Jessica Sook Yuin, Mok, Bobo Wing-Yee, Campisi, Laura, Jordan, Tristan, Yildiz, Soner, Parameswaran, Sreeja, Wayman, Joseph A., Gaudreault, Natasha N., Meekins, David A., Indran, Sabarish V., Morozov, Igor, Trujillo, Jessie D., Fstkchyan, Yesai S., Rathnasinghe, Raveen, Zhu, Zeyu, Zheng, Simin, Zhao, Nan, White, Kris, Ray-Jones, Helen, Malysheva, Valeriya, Thiecke, Michiel J., Lau, Siu-Ying, Liu, Honglian, Zhang, Anna Junxia, Lee, Andrew Chak-Yiu, Liu, Wen-Chun, Jangra, Sonia, Escalera, Alba, Aydillo, Teresa, Melo, Betsaida Salom, Guccione, Ernesto, Sebra, Robert, Shum, Elaine, Bakker, Jan, Kaufman, David A., Moreira, Andre L., Carossino, Mariano, Balasuriya, Udeni B.R., Byun, Minji, Albrecht, Randy A., Schotsaert, Michael, Garcia-Sastre, Adolfo, Chanda, Sumit K., Miraldi, Emily R., Jeyasekharan, Anand D., TenOever, Benjamin R., Spivakov, Mikhail, Weirauch, Matthew T., Heinz, Sven, Chen, Honglin, Benner, Christopher, Richt, Juergen A., Marazzi, Ivan
Published in Cell (13.05.2021)
Published in Cell (13.05.2021)
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