Improved precursor-directed biosynthesis in E. coli via directed evolution
Lee, Ho Young, Harvey, Colin J B, Cane, David E, Khosla, Chaitan
Published in Journal of antibiotics (01.01.2011)
Published in Journal of antibiotics (01.01.2011)
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Journal Article
In vitro and in vivo activity of frenolicin B against Plasmodium falciparum and P berghei
Fitzgerald, Jay T, Henrich, Philipp P, O'Brien, Connor, Krause, Michael, Ekland, Eric H, Mattheis, Corinna, Sá, Juliana M, Fidock, David, Khosla, Chaitan
Published in Journal of antibiotics (01.12.2011)
Published in Journal of antibiotics (01.12.2011)
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Journal Article
Assessing the Balance between Protein−Protein Interactions and Enzyme−Substrate Interactions in the Channeling of Intermediates between Polyketide Synthase Modules
Wu, Nicholas, Tsuji, Stuart Y, Cane, David E, Khosla, Chaitan
Published in Journal of the American Chemical Society (11.07.2001)
Published in Journal of the American Chemical Society (11.07.2001)
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Journal Article
Catalysis, Specificity, and ACP Docking Site of Streptomyces coelicolor Malonyl-CoA:ACP Transacylase
Keatinge-Clay, Adrian T., Shelat, Anang A., Savage, David F., Tsai, Shiou-Chuan, Miercke, Larry J.W., O'Connell, Joseph D., Khosla, Chaitan, Stroud, Robert M.
Published in Structure (London) (01.02.2003)
Published in Structure (London) (01.02.2003)
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Journal Article
Reconstituting Modular Activity from Separated Domains of 6-Deoxyerythronolide B Synthase
Kim, Chu-Young, Alekseyev, Viktor Y, Chen, Alice Y, Tang, Yinyan, Cane, David E, Khosla, Chaitan
Published in Biochemistry (Easton) (09.11.2004)
Published in Biochemistry (Easton) (09.11.2004)
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Journal Article
Enhancing the Modularity of the Modular Polyketide Synthases: Transacylation in Modular Polyketide Synthases Catalyzed by Malonyl-CoA:ACP Transacylase
Kumar, Pawan, Koppisch, Andrew T, Cane, David E, Khosla, Chaitan
Published in Journal of the American Chemical Society (26.11.2003)
Published in Journal of the American Chemical Society (26.11.2003)
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Journal Article
Kinetic and Structural Analysis of a New Group of Acyl-CoA Carboxylases Found in Streptomyces coelicolor A3(2)
Diacovich, Lautaro, Peirú, Salvador, Kurth, Daniel, Rodríguez, Eduardo, Podestá, Florencio, Khosla, Chaitan, Gramajo, Hugo
Published in The Journal of biological chemistry (23.08.2002)
Published in The Journal of biological chemistry (23.08.2002)
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Journal Article
Metabolic Engineering of a Methylmalonyl-CoA Mutase−Epimerase Pathway for Complex Polyketide Biosynthesis in Escherichia coli
Dayem, Linda C, Carney, John R, Santi, Daniel V, Pfeifer, Blaine A, Khosla, Chaitan, Kealey, James T
Published in Biochemistry (Easton) (23.04.2002)
Published in Biochemistry (Easton) (23.04.2002)
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Journal Article
Engineered Biosynthesis of a Complete Macrolactone in a Heterologous Host
Kao, Camilla M., Katz, Leonard, Khosla, Chaitan
Published in Science (American Association for the Advancement of Science) (22.07.1994)
Published in Science (American Association for the Advancement of Science) (22.07.1994)
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Journal Article
Engineered Biosynthesis of Novel Polyketides
McDaniel, Robert, Ebert-Khosla, Susanne, Hopwood, David A., Khosla, Chaitan
Published in Science (American Association for the Advancement of Science) (03.12.1993)
Published in Science (American Association for the Advancement of Science) (03.12.1993)
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Journal Article
Epothilone C Macrolactonization and Hydrolysis Are Catalyzed by the Isolated Thioesterase Domain of Epothilone Polyketide Synthase
Boddy, Christopher N, Schneider, Tanya L, Hotta, Kinya, Walsh, Christopher T, Khosla, Chaitan
Published in Journal of the American Chemical Society (26.03.2003)
Published in Journal of the American Chemical Society (26.03.2003)
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Journal Article