Inhibition of the cGAS‐STING pathway ameliorates the premature senescence hallmarks of Ataxia‐Telangiectasia brain organoids
Aguado, Julio, Chaggar, Harman K., Gómez‐Inclán, Cecilia, Shaker, Mohammed R., Leeson, Hannah C., Mackay‐Sim, Alan, Wolvetang, Ernst J.
Published in Aging cell (01.09.2021)
Published in Aging cell (01.09.2021)
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Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology
Aguado, Julio, Amarilla, Alberto A, Taherian Fard, Atefeh, Albornoz, Eduardo A, Tyshkovskiy, Alexander, Schwabenland, Marius, Chaggar, Harman K, Modhiran, Naphak, Gómez-Inclán, Cecilia, Javed, Ibrahim, Baradar, Alireza A, Liang, Benjamin, Peng, Lianli, Dharmaratne, Malindrie, Pietrogrande, Giovanni, Padmanabhan, Pranesh, Freney, Morgan E, Parry, Rhys, Sng, Julian D J, Isaacs, Ariel, Khromykh, Alexander A, Valenzuela Nieto, Guillermo, Rojas-Fernandez, Alejandro, Davis, Thomas P, Prinz, Marco, Bengsch, Bertram, Gladyshev, Vadim N, Woodruff, Trent M, Mar, Jessica C, Watterson, Daniel, Wolvetang, Ernst J
Published in Nature aging (01.12.2023)
Published in Nature aging (01.12.2023)
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Ataxia Telangiectasia patient-derived neuronal and brain organoid models reveal mitochondrial dysfunction and oxidative stress
Leeson, Hannah C., Aguado, Julio, Gómez-Inclán, Cecilia, Chaggar, Harman Kaur, Fard, Atefah Taherian, Hunter, Zoe, Lavin, Martin F., Mackay-Sim, Alan, Wolvetang, Ernst J.
Published in Neurobiology of disease (01.09.2024)
Published in Neurobiology of disease (01.09.2024)
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Ataxia Telangiectasia iPSC line generated from a patient olfactory biopsy identifies novel disease-causing mutations
Leeson, Hannah C., Hunter, Zoe, Chaggar, Harman Kaur, Lavin, Martin F., Mackay-Sim, Alan, Wolvetang, Ernst J.
Published in Stem cell research (01.10.2021)
Published in Stem cell research (01.10.2021)
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Klotho inhibits neuronal senescence in human brain organoids
Shaker, Mohammed R., Aguado, Julio, Chaggar, Harman Kaur, Wolvetang, Ernst J.
Published in npj aging and mechanisms of disease (02.08.2021)
Published in npj aging and mechanisms of disease (02.08.2021)
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Zika virus noncoding RNA cooperates with the viral protein NS5 to inhibit STAT1 phosphorylation and facilitate viral pathogenesis
Slonchak, Andrii, Wang, Xiaohui, Aguado, Julio, Sng, Julian D J, Chaggar, Harman, Freney, Morgan E, Yan, Kexin, Torres, Francisco J, Amarilla, Alberto A, Balea, Rickyle, Setoh, Yin Xiang, Peng, Nias, Watterson, Daniel, Wolvetang, Ernst, Suhrbier, Andreas, Khromykh, Alexander A
Published in Science advances (02.12.2022)
Published in Science advances (02.12.2022)
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Zika Virus sfRNA Plays an Essential Role in the Infection of Insects and Mammals
Andrii Slonchak, Leon E. Hugo, Morgan Freney, Alberto A Amarilla, Sonja Hall-Mendelin, Kexin Yan, Francisco Torres, Yin Xiang Setoh, Nias Peng, Harman K Chaggar, Andrew Van Den Hurk, Ernst Wolvetang, Andreas Suhrbier, Gregor J. Devine, Alexander A Khromykh
Published in Proceedings (01.07.2020)
Published in Proceedings (01.07.2020)
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Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology
Aguado, Julio, Amarilla, Alberto A, Atefeh Taherian Fard, Albornoz, Eduardo A, Tyshkovskiy, Alexander, Schwabenland, Marius, Harman Chaggar, Modhiran, Naphak, Gomez-Inclan, Cecilia, Ibrahim, Javed, Baradar, Alireza, Liang, Benjamin, Dharmaratne, Malindrie, Pietrogrande, Giovanni, Padmanabhan, Pranesh, Morgan Freney, Parry, Rhys, Sng, Julian, Isaacs, Ariel, Khromykh, Alexander, Rojas-Fernandez, Alejandro, Davis, Thomas, Prinz, Marco, Bengsch, Bertram, Gladyshev, Vadim N, Woodruff, Trent M, Mar, Jessica C, Watterson, Daniel, Wolvetang, Ernst J
Published in bioRxiv (18.01.2023)
Published in bioRxiv (18.01.2023)
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Zika virus noncoding RNA cooperates with the viral protein NS5 to inhibit STAT1 phosphorylation and facilitate viral pathogenesis
Andrii Slonchak Dr, Wang, Xiaohui, Harman Chaggar Ms, Aguado, Julio, Freney, Morgan, Yan, Kexin, Torres, Francisco J, Amarilla, Alberto A, Rickyle Balea Mr, Julian D J Sng Mr, Yin, Xiang Setoh, Nias Peng Mr, Watterson, Daniel, Ernst Wolvetang Prof, Suhrbier, Andreas, Khromykh, Alexander A
Published in bioRxiv (19.05.2021)
Published in bioRxiv (19.05.2021)
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