Increased brain-derived neurotrophic factor (BDNF) expression in the ventral tegmental area during cocaine abstinence is associated with increased histone acetylation at BDNF exon I-containing promoters
Schmidt, Heath D., Sangrey, Gavin R., Darnell, Shayna B., Schassburger, Rachel L., Cha, Jang-Ho J., Pierce, R. Christopher, Sadri-Vakili, Ghazaleh
Published in Journal of neurochemistry (01.01.2012)
Published in Journal of neurochemistry (01.01.2012)
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Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine
Sadri-Vakili, Ghazaleh, Kumaresan, Vidhya, Schmidt, Heath D, Famous, Katie R, Chawla, Prianka, Vassoler, Fair M, Overland, Ryan P, Xia, Eva, Bass, Caroline E, Terwilliger, Ernest F, Pierce, R Christopher, Cha, Jang-Ho J
Published in The Journal of neuroscience (01.09.2010)
Published in The Journal of neuroscience (01.09.2010)
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Genome-wide histone acetylation is altered in a transgenic mouse model of Huntington's disease
McFarland, Karen N, Das, Sudeshna, Sun, Ting Ting, Leyfer, Dmitri, Xia, Eva, Sangrey, Gavin R, Kuhn, Alexandre, Luthi-Carter, Ruth, Clark, Timothy W, Sadri-Vakili, Ghazaleh, Cha, Jang-Ho J
Published in PloS one (27.07.2012)
Published in PloS one (27.07.2012)
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Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease
Friedlander, Robert M, Chen, Minghua, Ona, Victor O, Li, Mingwei, Ferrante, Robert J, Fink, Klaus B, Zhu, Shan, Bian, Jie, Guo, Lei, Farrell, Laurie A, Hersch, Steve M, Hobbs, Wendy, Vonsattel, Jean-Paul, Cha, Jang-Ho J
Published in Nature medicine (01.07.2000)
Published in Nature medicine (01.07.2000)
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Sp1 Is Up-regulated in Cellular and Transgenic Models of Huntington Disease, and Its Reduction Is Neuroprotective
Qiu, Zhihua, Norflus, Fran, Singh, Bhupinder, Swindell, Mary K., Buzescu, Rodica, Bejarano, Michelle, Chopra, Raman, Zucker, Birgit, Benn, Caroline L., DiRocco, Derek P., Cha, Jang-Ho J., Ferrante, Robert J., Hersch, Steven M.
Published in The Journal of biological chemistry (16.06.2006)
Published in The Journal of biological chemistry (16.06.2006)
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Decreased association of the transcription factor Sp1 with genes downregulated in Huntington's disease
Chen-Plotkin, Alice S., Sadri-Vakili, Ghazaleh, Yohrling, George J., Braveman, Melissa W., Benn, Caroline L., Glajch, Kelly E., DiRocco, Derek P., Farrell, Laurie A., Krainc, Dimitri, Gines, Silvia, MacDonald, Marcy E., Cha, Jang-Ho J.
Published in Neurobiology of disease (01.05.2006)
Published in Neurobiology of disease (01.05.2006)
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Contribution of nuclear and extranuclear polyQ to neurological phenotypes in mouse models of Huntington's disease
Benn, Caroline L., Landles, Christian, Li, He, Strand, Andrew D., Woodman, Ben, Sathasivam, Kirupa, Li, Shi-Hua, Ghazi-Noori, Shabnam, Hockly, Emma, Faruque, Syed M.N.N., Cha, Jang-Ho J., Sharpe, Paul T., Olson, James M., Li, Xiao-Jiang, Bates, Gillian P.
Published in Human molecular genetics (15.10.2005)
Published in Human molecular genetics (15.10.2005)
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Altered Brain Neurotransmitter Receptors in Transgenic Mice Expressing a Portion of an Abnormal Human Huntington Disease Gene
Cha, Jang-Ho J., Kosinski, Christoph M., Kerner, Julie A., Alsdorf, Stephen A., Mangiarini, Laura, Davies, Stephen W., Penney, John B., Bates, Gillian P., Young, Anne B.
Published in Proceedings of the National Academy of Sciences - PNAS (26.05.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (26.05.1998)
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Mechanisms of Disease: histone modifications in Huntington's disease
Cha, Jang-Ho J, Sadri-Vakili, Ghazaleh
Published in Nature clinical practice. Neurology (01.06.2006)
Published in Nature clinical practice. Neurology (01.06.2006)
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CaMKII: a biochemical bridge linking accumbens dopamine and glutamate systems in cocaine seeking
Schmidt, Heath D, Bass, Caroline E, Terwilliger, Ernest F, Pierce, R Christopher, Sadri-Vakili, Ghazaleh, Famous, Katie R, Anderson, Sharon M, Cha, Jang-Ho J, Kumaresan, Vidhya
Published in Nature neuroscience (01.03.2008)
Published in Nature neuroscience (01.03.2008)
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Huntingtin Modulates Transcription, Occupies Gene Promoters In Vivo, and Binds Directly to DNA in a Polyglutamine-Dependent Manner
Benn, Caroline L, Sun, Tingting, Sadri-Vakili, Ghazaleh, McFarland, Karen N, DiRocco, Derek P, Yohrling, George J, Clark, Timothy W, Bouzou, Berengere, Cha, Jang-Ho J
Published in The Journal of neuroscience (15.10.2008)
Published in The Journal of neuroscience (15.10.2008)
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Phosphorylation-Dependent Trafficking of GluR2-Containing AMPA Receptors in the Nucleus Accumbens Plays a Critical Role in the Reinstatement of Cocaine Seeking
Famous, Katie R, Kumaresan, Vidhya, Sadri-Vakili, Ghazaleh, Schmidt, Heath D, Mierke, Dale F, Cha, Jang-Ho J, Pierce, R. Christopher
Published in The Journal of neuroscience (22.10.2008)
Published in The Journal of neuroscience (22.10.2008)
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Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage
Kuhn, Alexandre, Goldstein, Darlene R., Hodges, Angela, Strand, Andrew D., Sengstag, Thierry, Kooperberg, Charles, Becanovic, Kristina, Pouladi, Mahmoud A., Sathasivam, Kirupa, Cha, Jang-Ho J., Hannan, Anthony J., Hayden, Michael R., Leavitt, Blair R., Dunnett, Stephen B., Ferrante, Robert J., Albin, Roger, Shelbourne, Peggy, Delorenzi, Mauro, Augood, Sarah J., Faull, Richard L.M., Olson, James M., Bates, Gillian P., Jones, Lesley, Luthi-Carter, Ruth
Published in Human molecular genetics (01.08.2007)
Published in Human molecular genetics (01.08.2007)
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Complex alteration of NMDA receptors in transgenic Huntington's disease mouse brain: analysis of mRNA and protein expression, plasma membrane association, interacting proteins, and phosphorylation
Luthi-Carter, Ruth, Apostol, Barbara L, Dunah, Anthone W, DeJohn, Molly M, Farrell, Laurie A, Bates, Gillian P, Young, Anne B, Standaert, David G, Thompson, Leslie M, Cha, Jang-Ho J
Published in Neurobiology of disease (01.12.2003)
Published in Neurobiology of disease (01.12.2003)
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Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models
Sadri-Vakili, Ghazaleh, Bouzou, Bérengère, Benn, Caroline L., Kim, Mee-Ohk, Chawla, Prianka, Overland, Ryan P., Glajch, Kelly E., Xia, Eva, Qiu, Zhihua, Hersch, Steven M., Clark, Timothy W., Yohrling, George J., Cha, Jang-Ho J.
Published in Human molecular genetics (01.06.2007)
Published in Human molecular genetics (01.06.2007)
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MeCP2: a novel Huntingtin interactor
McFarland, Karen N, Huizenga, Megan N, Darnell, Shayna B, Sangrey, Gavin R, Berezovska, Oksana, Cha, Jang-Ho J, Outeiro, Tiago F, Sadri-Vakili, Ghazaleh
Published in Human molecular genetics (15.02.2014)
Published in Human molecular genetics (15.02.2014)
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Forebrain Adenosine A2A Receptors Contribute to L-3,4-Dihydroxyphenylalanine-Induced Dyskinesia in Hemiparkinsonian Mice
Xiao, Danqing, Bastia, Elena, Xu, Yue-Hang, Benn, Caroline L, Cha, Jang-Ho J, Peterson, Tracy S, Chen, Jiang-Fan, Schwarzschild, Michael A
Published in The Journal of neuroscience (27.12.2006)
Published in The Journal of neuroscience (27.12.2006)
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Genome-wide increase in histone H2A ubiquitylation in a mouse model of Huntington's disease
McFarland, Karen N, Das, Sudeshna, Sun, Ting Ting, Leyfer, Dmitri, Kim, Mee-Ohk, Xia, Eva, Sangrey, Gavin R, Kuhn, Alexandre, Luthi-Carter, Ruth, Clark, Timothy W, Sadri-Vakili, Ghazaleh, Cha, Jang-Ho J
Published in Journal of Huntington's disease (2013)
Published in Journal of Huntington's disease (2013)
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Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease
Friedlander, Robert M, Ona, Victor O, Li, Mingwei, Vonsattel, Jean Paul G, Andrews, L. John, Khan, Sohail Q, Chung, Woosik M, Frey, Ariel S, Menon, Anil S, Li, Xiao-Jiang, Stieg, Philip E, Yuan, Junying, Penney, John B, Young, Anne B, Cha, Jang-Ho J
Published in Nature (London) (20.05.1999)
Published in Nature (London) (20.05.1999)
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