Flipping the molecular switch for innate protection and repair of tissues: Long-lasting effects of a non-erythropoietic small peptide engineered from erythropoietin
Collino, Massimo, Thiemermann, Christoph, Cerami, Anthony, Brines, Michael
Published in Pharmacology & therapeutics (Oxford) (01.07.2015)
Published in Pharmacology & therapeutics (Oxford) (01.07.2015)
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Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage
Shi, Jing, Knevel, Rachel, Suwannalai, Parawee, van der Linden, Michael P, Janssen, George M. C, van Veelen, Peter A, Levarht, Nivine E. W, van der Helm-van Mil, Annette H. M, Cerami, Anthony, Huizinga, Tom W. J, Toes, Rene E. M, Trouw, Leendert A
Published in Proceedings of the National Academy of Sciences - PNAS (18.10.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (18.10.2011)
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Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin
Brines, Michael, Patel, Nimesh S.A, Villa, Pia, Brines, Courtenay, Mennini, Tiziana, De Paola, Massimiliano, Erbayraktar, Zubeyde, Erbayraktar, Serhat, Sepodes, Bruno, Thiemermann, Christoph, Ghezzi, Pietro, Yamin, Michael, Hand, Carla C, Xie, Qiao-wen, Coleman, Thomas, Cerami, Anthony
Published in Proceedings of the National Academy of Sciences - PNAS (05.08.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (05.08.2008)
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Erythropoietin Mediates Tissue Protection through an Erythropoietin and Common β-Subunit Heteroreceptor
Brines, Michael, Grasso, Giovanni, Fiordaliso, Fabio, Sfacteria, Alessandra, Ghezzi, Pietro, Fratelli, Maddalena, Latini, Roberto, Xie, Qiao-wen, Smart, John, Su-Rick, Chiao-ju, Pobre, Eileen, Diaz, Deborah, Gomez, Daniel, Hand, Carla, Coleman, Thomas, Cerami, Anthony
Published in Proceedings of the National Academy of Sciences - PNAS (12.10.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (12.10.2004)
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Recombinant Human Erythropoietin Protects the Myocardium from Ischemia-Reperfusion Injury and Promotes Beneficial Remodeling
Calvillo, Laura, Latini, Roberto, Kajstura, Jan, Leri, Annarosa, Anversa, Piero, Ghezzi, Pietro, Salio, Monica, Cerami, Anthony, Brines, Michael
Published in Proceedings of the National Academy of Sciences - PNAS (15.04.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (15.04.2003)
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Recognition of citrullinated and carbamylated proteins by human antibodies: specificity, cross-reactivity and the ‘AMC-Senshu’ method
Shi, Jing, Willemze, Annemiek, Janssen, George M C, van Veelen, Peter A, Drijfhout, Jan Wouter, Cerami, Anthony, Huizinga, Tom W J, Trouw, Leendert A, Toes, René E
Published in Annals of the rheumatic diseases (01.01.2013)
Published in Annals of the rheumatic diseases (01.01.2013)
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ARA 290 improves symptoms in patients with sarcoidosis-associated small nerve fiber loss and increases corneal nerve fiber density
Dahan, Albert, Dunne, Ann, Swartjes, Maarten, Proto, Paolo L, Heij, Lara, Vogels, Oscar, van Velzen, Monique, Sarton, Elise, Niesters, Marieke, Tannemaat, Martijn R, Cerami, Anthony, Brines, Michael
Published in Molecular medicine (Cambridge, Mass.) (2013)
Published in Molecular medicine (Cambridge, Mass.) (2013)
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Alternative erythropoietin-mediated signaling prevents secondary microvascular thrombosis and inflammation within cutaneous burns
Bohr, Stefan, Patel, Suraj J., Shen, Keyue, Vitalo, Antonia G., Brines, Michael, Cerami, Anthony, Berthiaume, Francois, Yarmush, Martin L.
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2013)
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Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis
Villa, Pia, Bigini, Paolo, Mennini, Tiziana, Agnello, Davide, Laragione, Teresa, Cagnotto, Alfredo, Viviani, Barbara, Marinovich, Marina, Cerami, Anthony, Coleman, Thomas R, Brines, Michael, Ghezzi, Pietro
Published in The Journal of experimental medicine (15.09.2003)
Published in The Journal of experimental medicine (15.09.2003)
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The erythropoietin‐derived peptide ARA 284 reduces tissue wasting and improves survival in a rat model of cancer cachexia
Palus, Sandra, Elkina, Yulia, Braun, Tanja, Haehling, Stephan, Döhner, Wolfram, Anker, Stefan D., Cerami, Anthony, Brines, Michael, Springer, Jochen
Published in Journal of cachexia, sarcopenia and muscle (01.08.2022)
Published in Journal of cachexia, sarcopenia and muscle (01.08.2022)
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Cibinetide Protects Isolated Human Islets in a Stressful Environment and Improves Engraftment in the Perspective of Intra Portal Islet Transplantation
Yao, Ming, Domogatskaya, Anna, Ågren1, Nils, Watanabe, Masaaki, Tokodai, Kazuaki, Brines, Michael, Cerami, Anthony, Ericzon, Bo-Göran, Kumagai-Braesch, Makiko, Lundgren, Torbjörn
Published in Cell transplantation (2021)
Published in Cell transplantation (2021)
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Erythropoietin Crosses the Blood-Brain Barrier to Protect against Experimental Brain Injury
Brines, Michael L., Ghezzi, Pietro, Keenan, Sonja, Agnello, Davide, De Lanerolle, Nihal C., Cerami, Carla, Itri, Loretta M., Cerami, Anthony
Published in Proceedings of the National Academy of Sciences - PNAS (12.09.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (12.09.2000)
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Modulation of cellular stress response via the erythropoietin/CD131 heteroreceptor complex in mouse mesenchymal-derived cells
Bohr, Stefan, Patel, Suraj J., Vasko, Radovan, Shen, Keyue, Iracheta-Vellve, Arvin, Lee, Jungwoo, Bale, Shyam Sundhar, Chakraborty, Nilay, Brines, Michael, Cerami, Anthony, Berthiaume, Francois, Yarmush, Martin L.
Published in Journal of molecular medicine (Berlin, Germany) (01.02.2015)
Published in Journal of molecular medicine (Berlin, Germany) (01.02.2015)
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Journal Article
ARA 290 for treatment of small fiber neuropathy in sarcoidosis
van Velzen, Monique, Heij, Lara, Niesters, Marieke, Cerami, Anthony, Dunne, Ann, Dahan, Albert, Brines, Michael
Published in Expert opinion on investigational drugs (01.04.2014)
Published in Expert opinion on investigational drugs (01.04.2014)
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Journal Article
Erythropoietin modulation of astrocyte water permeability as a component of neuroprotection
Gunnarson, Eli, Song, Yutong, Kowalewski, Jacob M, Brismar, Hjalmar, Brines, Michael, Cerami, Anthony, Andersson, Ulf, Zelenina, Marina, Aperia, Anita
Published in Proceedings of the National Academy of Sciences - PNAS (03.02.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (03.02.2009)
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Journal Article
Recombinant Human Erythropoietin Counteracts Secondary Injury and Markedly Enhances Neurological Recovery from Experimental Spinal Cord Trauma
Gorio, Alfredo, Gokmen, Necati, Erbayraktar, Serhat, Yilmaz, Osman, Madaschi, Laura, Cichetti, Cinzia, Di Giulio, Anna Maria, Vardar, Enver, Cerami, Anthony, Brines, Michael
Published in Proceedings of the National Academy of Sciences - PNAS (09.07.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (09.07.2002)
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Journal Article
Cardioprotection by a nonerythropoietic, tissue-protective peptide mimicking the 3D structure of erythropoietin
Ueba, Hiroto, Brines, Michael, Yamin, Michael, Umemoto, Tomio, Ako, Junya, Momomura, Shin-ichi, Cerami, Anthony, Kawakami, Masanobu, Dinarello, Charles A.
Published in Proceedings of the National Academy of Sciences - PNAS (10.08.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (10.08.2010)
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Journal Article
Erythropoietin Prevents Neuronal Apoptosis after Cerebral Ischemia and Metabolic Stress
Sirén, Anna-Leena, Fratelli, Maddalena, Brines, Michael, Goemans, Christoph, Casagrande, Simona, Lewczuk, Piotr, Keenan, Sonja, Gleiter, Christoph, Pasquali, Claudio, Capobianco, Annalisa, Mennini, Tiziana, Heumann, Rolf, Cerami, Anthony, Ehrenreich, Hannelore, Ghezzi, Pietro
Published in Proceedings of the National Academy of Sciences - PNAS (27.03.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (27.03.2001)
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Reduced functional deficits, neuroinflammation, and secondary tissue damage after treatment of stroke by nonerythropoietic erythropoietin derivatives
Villa, Pia, van Beek, Johan, Larsen, Anna Kirstine, Gerwien, Jens, Christensen, Søren, Cerami, Anthony, Brines, Michael, Leist, Marcel, Ghezzi, Pietro, Torup, Lars
Published in Journal of cerebral blood flow and metabolism (01.03.2007)
Published in Journal of cerebral blood flow and metabolism (01.03.2007)
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