Maximizing the Therapeutic Potential of HSP90 Inhibitors
Butler, Lisa M, Ferraldeschi, Roberta, Armstrong, Heather K, Centenera, Margaret M, Workman, Paul
Published in Molecular cancer research (01.11.2015)
Published in Molecular cancer research (01.11.2015)
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Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis
Nassar, Zeyad D, Mah, Chui Yan, Dehairs, Jonas, Burvenich, Ingrid Jg, Irani, Swati, Centenera, Margaret M, Helm, Madison, Shrestha, Raj K, Moldovan, Max, Don, Anthony S, Holst, Jeff, Scott, Andrew M, Horvath, Lisa G, Lynn, David J, Selth, Luke A, Hoy, Andrew J, Swinnen, Johannes V, Butler, Lisa M
Published in eLife (20.07.2020)
Published in eLife (20.07.2020)
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ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer
Centenera, Margaret M, Scott, Julia S, Machiels, Jelle, Nassar, Zeyad D, Miller, Deanna C, Zinonos, Irene, Dehairs, Jonas, Burvenich, Ingrid J G, Zadra, Giorgia, Chetta, Paolo M, Bango, Clyde, Evergren, Emma, Ryan, Natalie K, Gillis, Joanna L, Mah, Chui Yan, Tieu, Terence, Hanson, Adrienne R, Carelli, Ryan, Bloch, Katarzyna, Panagopoulos, Vasilios, Waelkens, Etienne, Derua, Rita, Williams, Elizabeth D, Evdokiou, Andreas, Cifuentes-Rius, Anna, Voelcker, Nicolas H, Mills, Ian G, Tilley, Wayne D, Scott, Andrew M, Loda, Massimo, Selth, Luke A, Swinnen, Johannes V, Butler, Lisa M
Published in Cancer research (Chicago, Ill.) (01.04.2021)
Published in Cancer research (Chicago, Ill.) (01.04.2021)
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Peptidomimetic targeting of critical androgen receptor–coregulator interactions in prostate cancer
Ravindranathan, Preethi, Lee, Tae-Kyung, Yang, Lin, Centenera, Margaret M., Butler, Lisa, Tilley, Wayne D., Hsieh, Jer-Tsong, Ahn, Jung-Mo, Raj, Ganesh V.
Published in Nature communications (28.05.2013)
Published in Nature communications (28.05.2013)
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The role of RHAMM in cancer: Exposing novel therapeutic vulnerabilities
Hinneh, Josephine A., Gillis, Joanna L., Moore, Nicole L., Butler, Lisa M., Centenera, Margaret M.
Published in Frontiers in oncology (10.08.2022)
Published in Frontiers in oncology (10.08.2022)
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Extracellular Fatty Acids Are the Major Contributor to Lipid Synthesis in Prostate Cancer
Balaban, Seher, Nassar, Zeyad D, Zhang, Alison Y, Hosseini-Beheshti, Elham, Centenera, Margaret M, Schreuder, Mark, Lin, Hui-Ming, Aishah, Atqiya, Varney, Bianca, Liu-Fu, Frank, Lee, Lisa S, Nagarajan, Shilpa R, Shearer, Robert F, Hardie, Rae-Anne, Raftopulos, Nikki L, Kakani, Meghna S, Saunders, Darren N, Holst, Jeff, Horvath, Lisa G, Butler, Lisa M, Hoy, Andrew J
Published in Molecular cancer research (01.04.2019)
Published in Molecular cancer research (01.04.2019)
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Dual roles of PARP-1 promote cancer growth and progression
Schiewer, Matthew J, Goodwin, Jonathan F, Han, Sumin, Brenner, J Chad, Augello, Michael A, Dean, Jeffry L, Liu, Fengzhi, Planck, Jamie L, Ravindranathan, Preethi, Chinnaiyan, Arul M, McCue, Peter, Gomella, Leonard G, Raj, Ganesh V, Dicker, Adam P, Brody, Jonathan R, Pascal, John M, Centenera, Margaret M, Butler, Lisa M, Tilley, Wayne D, Feng, Felix Y, Knudsen, Karen E
Published in Cancer discovery (01.12.2012)
Published in Cancer discovery (01.12.2012)
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A patient‐derived explant (PDE) model of hormone‐dependent cancer
Centenera, Margaret M., Hickey, Theresa E., Jindal, Shalini, Ryan, Natalie K., Ravindranathan, Preethi, Mohammed, Hisham, Robinson, Jessica L., Schiewer, Matthew J., Ma, Shihong, Kapur, Payal, Sutherland, Peter D., Hoffmann, Clive E., Roehrborn, Claus G., Gomella, Leonard G., Carroll, Jason S., Birrell, Stephen N., Knudsen, Karen E., Raj, Ganesh V., Butler, Lisa M., Tilley, Wayne D.
Published in Molecular oncology (01.09.2018)
Published in Molecular oncology (01.09.2018)
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Effect of FAK inhibitor VS‐6063 (defactinib) on docetaxel efficacy in prostate cancer
Lin, Hui‐Ming, Lee, Brian Y., Castillo, Lesley, Spielman, Calan, Grogan, Judith, Yeung, Nicole K., Kench, James G., Stricker, Phillip D., Haynes, Anne‐Maree, Centenera, Margaret M., Butler, Lisa M., Shreeve, S. Martin, Horvath, Lisa G., Daly, Roger J.
Published in The Prostate (01.03.2018)
Published in The Prostate (01.03.2018)
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Identification of Novel Response and Predictive Biomarkers to Hsp90 Inhibitors Through Proteomic Profiling of Patient-derived Prostate Tumor Explants
Nguyen, Elizabeth V., Centenera, Margaret M., Moldovan, Max, Das, Rajdeep, Irani, Swati, Vincent, Andrew D., Chan, Howard, Horvath, Lisa G., Lynn, David J., Daly, Roger J., Butler, Lisa M.
Published in Molecular & cellular proteomics (01.08.2018)
Published in Molecular & cellular proteomics (01.08.2018)
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Ex vivo culture of human prostate tissue and drug development
Centenera, Margaret M., Raj, Ganesh V., Knudsen, Karen E., Tilley, Wayne D., Butler, Lisa M.
Published in Nature reviews. Urology (01.08.2013)
Published in Nature reviews. Urology (01.08.2013)
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Evidence for Efficacy of New Hsp90 Inhibitors Revealed by Ex Vivo Culture of Human Prostate Tumors
CENTENERA, Margaret M, GILLIS, Joanna L, YEADON, Trina, TILLEY, Wayne D, BUTLER, Lisa M, HANSON, Adrienne R, JINDAL, Shalini, TAYLOR, Renea A, RISBRIDGER, Gail P, SUTHERLAND, Peter D, SCHER, Howard I, RAJ, Ganesh V, KNUDSEN, Karen E
Published in Clinical cancer research (01.07.2012)
Published in Clinical cancer research (01.07.2012)
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A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth
Gillis, Joanna L, Hinneh, Josephine A, Ryan, Natalie K, Irani, Swati, Moldovan, Max, Quek, Lake-Ee, Shrestha, Raj K, Hanson, Adrienne R, Xie, Jianling, Hoy, Andrew J, Holst, Jeff, Centenera, Margaret M, Mills, Ian G, Lynn, David J, Selth, Luke A, Butler, Lisa M
Published in eLife (12.08.2021)
Published in eLife (12.08.2021)
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Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion
Armstrong, Heather K., Gillis, Joanna L., Johnson, Ian R. D., Nassar, Zeyad D., Moldovan, Max, Levrier, Claire, Sadowski, Martin C., Chin, Mei Yieng, Tomlinson Guns, Emma S., Tarulli, Gerard, Lynn, David J., Brooks, Douglas A., Selth, Luke A., Centenera, Margaret M., Butler, Lisa M.
Published in Scientific reports (01.02.2018)
Published in Scientific reports (01.02.2018)
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A Boolean-based machine learning framework identifies predictive biomarkers of HSP90-targeted therapy response in prostate cancer
Shin, Sung-Young, Centenera, Margaret M, Hodgson, Joshua T, Nguyen, Elizabeth V, Butler, Lisa M, Daly, Roger J, Nguyen, Lan K
Published in Frontiers in molecular biosciences (19.01.2023)
Published in Frontiers in molecular biosciences (19.01.2023)
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Androgen control of lipid metabolism in prostate cancer: novel insights and future applications
Butler, Lisa M, Centenera, Margaret M, Swinnen, Johannes V
Published in Endocrine-related cancer (01.05.2016)
Published in Endocrine-related cancer (01.05.2016)
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Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition
Butler, Lisa M, Mah, Chui Yan, Machiels, Jelle, Vincent, Andrew D, Irani, Swati, Mutuku, Shadrack M, Spotbeen, Xander, Bagadi, Muralidhararao, Waltregny, David, Moldovan, Max, Dehairs, Jonas, Vanderhoydonc, Frank, Bloch, Katarzyna, Das, Rajdeep, Stahl, Jurgen, Kench, James G, Gevaert, Thomas, Derua, Rita, Waelkens, Etienne, Nassar, Zeyad D, Selth, Luke A, Trim, Paul J, Snel, Marten F, Lynn, David J, Tilley, Wayne D, Horvath, Lisa G, Centenera, Margaret M, Swinnen, Johannes V
Published in Cancer research (Chicago, Ill.) (01.10.2021)
Published in Cancer research (Chicago, Ill.) (01.10.2021)
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Targeting hyaluronan-mediated motility receptor (HMMR) enhances response to androgen receptor signalling inhibitors in prostate cancer
Hinneh, Josephine A., Gillis, Joanna L., Mah, Chui Yan, Irani, Swati, Shrestha, Raj K., Ryan, Natalie K., Atsushi, Enomoto, Nassar, Zeyad D., Lynn, David J., Selth, Luke A., Kato, Masashi, Centenera, Margaret M., Butler, Lisa M.
Published in British journal of cancer (12.10.2023)
Published in British journal of cancer (12.10.2023)
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Journal Article
Androgen Receptor Inhibits Estrogen Receptor-α Activity and Is Prognostic in Breast Cancer
PETER, Amelia A, BUCHANAN, Grant, HENSHALL, Susan M, BIRRELL, Stephen N, COETZEE, Gerhard A, SUTHERLAND, Robert L, BUTLER, Lisa M, TILLEY, Wayne D, RICCIARDELLI, Carmela, BIANCO-MIOTTO, Tina, CENTENERA, Margaret M, HARRIS, Jonathan M, JINDAL, Shalini, SEGARA, Davendra, LI JIA, MOORE, Nicole L
Published in Cancer research (Chicago, Ill.) (01.08.2009)
Published in Cancer research (Chicago, Ill.) (01.08.2009)
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