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Hypomethylation at PANDAR promoter progressively induces senescence in adipocyte precursor cells in subjects with obesity and type 2 diabetes
Desiderio, Antonella, Pastorino, Monica, Campitelli, Michele, Prevenzano, Immacolata, De Palma, Fatima Domenica Elisa, Spinelli, Rosa, Parrillo, Luca, Longo, Michele, Milone, Marco, Miele, Claudia, Raciti, Gregory Alexander, Beguinot, Francesco
Published in The FASEB journal (15.10.2024)
Published in The FASEB journal (15.10.2024)
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Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
Kang, Tae-Won, Yevsa, Tetyana, Woller, Norman, Hoenicke, Lisa, Wuestefeld, Torsten, Dauch, Daniel, Hohmeyer, Anja, Gereke, Marcus, Rudalska, Ramona, Potapova, Anna, Iken, Marcus, Vucur, Mihael, Weiss, Siegfried, Heikenwalder, Mathias, Khan, Sadaf, Gil, Jesus, Bruder, Dunja, Manns, Michael, Schirmacher, Peter, Tacke, Frank, Ott, Michael, Luedde, Tom, Longerich, Thomas, Kubicka, Stefan, Zender, Lars
Published in Nature (London) (24.11.2011)
Published in Nature (London) (24.11.2011)
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Progressive Cellular Senescence Mediates Renal Dysfunction in Ischemic Nephropathy
Kim, Seo Rin, Puranik, Amrutesh S., Jiang, Kai, Chen, Xiaojun, Zhu, Xiang-Yang, Taylor, Ian, Khodadadi-Jamayran, Alireza, Lerman, Amir, Hickson, LaTonya J., Childs, Bennett G., Textor, Stephen C., Tchkonia, Tamara, Niewold, Timothy B., Kirkland, James L., Lerman, Lilach O.
Published in Journal of the American Society of Nephrology (01.08.2021)
Published in Journal of the American Society of Nephrology (01.08.2021)
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Vitamin D 3 inhibits p38 MAPK and senescence‐associated inflammatory mediator secretion by senescent fibroblasts that impacts immune responses during ageing
Sayegh, Souraya, Fantecelle, Carlos Henrique, Laphanuwat, Phatthamon, Subramanian, Priya, Rustin, Malcom H. A., Gomes, Daniel C. O., Akbar, Arne N., Chambers, Emma S.
Published in Aging cell (01.04.2024)
Published in Aging cell (01.04.2024)
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Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis
Moore, Camille, Blumhagen, Rachel Z., Yang, Ivana V., Walts, Avram, Powers, Julie, Walker, Tarik, Bishop, Makenna, Russell, Pamela, Vestal, Brian, Cardwell, Jonathan, Markin, Cheryl R., Mathai, Susan K., Schwarz, Marvin I., Steele, Mark P., Lee, Joyce, Brown, Kevin K., Loyd, James E., Crapo, James D., Silverman, Edwin K., Cho, Michael H., James, Judith A., Guthridge, Joel M., Cogan, Joy D., Kropski, Jonathan A., Swigris, Jeffrey J., Bair, Carol, Kim, Dong Soon, Ji, Wonjun, Kim, Hocheol, Song, Jin Woo, Maier, Lisa A., Pacheco, Karin A., Hirani, Nikhil, Poon, Azin S., Li, Feng, Jenkins, R. Gisli, Braybrooke, Rebecca, Saini, Gauri, Maher, Toby M., Molyneaux, Philip L., Saunders, Peter, Zhang, Yingze, Gibson, Kevin F., Kass, Daniel J., Rojas, Mauricio, Sembrat, John, Wolters, Paul J., Collard, Harold R., Sundy, John S., O’Riordan, Thomas, Strek, Mary E., Noth, Imre, Ma, Shwu-Fan, Porteous, Mary K., Kreider, Maryl E., Patel, Namrata B., Inoue, Yoshikazu, Hirose, Masaki, Arai, Toru, Akagawa, Shinobu, Eickelberg, Oliver, Fernandez, Isis Enlil, Behr, Jürgen, Mogulkoc, Nesrin, Corte, Tamera J., Glaspole, Ian, Tomassetti, Sara, Ravaglia, Claudia, Poletti, Venerino, Crestani, Bruno, Borie, Raphael, Kannengiesser, Caroline, Parfrey, Helen, Fiddler, Christine, Rassl, Doris, Molina-Molina, Maria, Machahua, Carlos, Worboys, Ana Montes, Gudmundsson, Gunnar, Isaksson, Helgi J., Lederer, David J., Podolanczuk, Anna J., Montesi, Sydney B., Bendstrup, Elisabeth, Danchel, Vivi, Selman, Moises, Pardo, Annie, Henry, Michael T., Keane, Michael P., Doran, Peter, Vašáková, Martina, Sterclova, Martina, Ryerson, Christopher J., Wilcox, Pearce G., Okamoto, Tsukasa, Furusawa, Haruhiko, Miyazaki, Yasunari, Laurent, Geoffrey, Baltic, Svetlana, Prele, Cecilia
Published in American journal of respiratory and critical care medicine (15.07.2019)
Published in American journal of respiratory and critical care medicine (15.07.2019)
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DNA damage checkpoints in stem cells, ageing and cancer
Sperka, Tobias, Wang, Jianwei, Rudolph, K. Lenhard
Published in Nature reviews. Molecular cell biology (01.09.2012)
Published in Nature reviews. Molecular cell biology (01.09.2012)
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Major depressive disorder and accelerated cellular aging: results from a large psychiatric cohort study
Verhoeven, J E, Révész, D, Epel, E S, Lin, J, Wolkowitz, O M, Penninx, B W J H
Published in Molecular psychiatry (01.08.2014)
Published in Molecular psychiatry (01.08.2014)
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Linking a role of lncRNAs (long non-coding RNAs) with insulin resistance, accelerated senescence, and inflammation in patients with type 2 diabetes
Sathishkumar, Chandrakumar, Prabu, Paramasivam, Mohan, Viswanathan, Balasubramanyam, Muthuswamy
Published in Human genomics (23.08.2018)
Published in Human genomics (23.08.2018)
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Oscillatory shear stress promotes endothelial senescence and atherosclerosis via STING activation
Dong, Mengdie, Chen, Minghong, Zhang, Yunjia, He, Xian, Min, Jiao, Tan, Yongkang, Wei, Huiyuan, Li, Xinyu, Chen, Xiang, Zheng, Longbin, Yin, Quanwen, Li, Xuesong, Chen, Hongshan, Jiang, Hong
Published in Biochemical and biophysical research communications (30.06.2024)
Published in Biochemical and biophysical research communications (30.06.2024)
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Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent functional decline
Hennrich, Marco L., Romanov, Natalie, Horn, Patrick, Jaeger, Samira, Eckstein, Volker, Steeples, Violetta, Ye, Fei, Ding, Ximing, Poisa-Beiro, Laura, Lai, Mang Ching, Lang, Benjamin, Boultwood, Jacqueline, Luft, Thomas, Zaugg, Judith B., Pellagatti, Andrea, Bork, Peer, Aloy, Patrick, Gavin, Anne-Claude, Ho, Anthony D.
Published in Nature communications (01.10.2018)
Published in Nature communications (01.10.2018)
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Short Leukocyte Telomere Length Predicts Risk of Diabetes in American Indians: the Strong Heart Family Study
Zhao, Jinying, Zhu, Yun, Lin, Jue, Matsuguchi, Tet, Blackburn, Elizabeth, Zhang, Ying, Cole, Shelley A., Best, Lyle G., Lee, Elisa T., Howard, Barbara V.
Published in Diabetes (New York, N.Y.) (01.01.2014)
Published in Diabetes (New York, N.Y.) (01.01.2014)
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Senescence-related genes are associated with the immunopathology signature of American tegumentary leishmaniasis lesions and may predict progression to mucosal leishmaniasis
Fantecelle, Carlos Henrique, Polaco Covre, Luciana, Lopes, Paola Oliveira, Sarmento, Isabela Valim, Decote-Ricardo, Debora, Geraldo Freire-de-Lima, Célio, de Matos Guedes, Herbert Leonel, Pimentel, Maria Inês Fernandes, Conceição-Silva, Fatima, Maretti-Mira, Ana C, Borges, Valéria M, Pedreira de Carvalho, Lucas, Carvalho, Edgar Marcelino de, Mosser, David, Falqueto, Aloisio, Akbar, Arne N, Gomes, Daniel Claudio Oliveira
Published in Clinical and experimental immunology (21.01.2025)
Published in Clinical and experimental immunology (21.01.2025)
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Childhood Maltreatment and Telomere Shortening: Preliminary Support for an Effect of Early Stress on Cellular Aging
Tyrka, Audrey R., Price, Lawrence H., Kao, Hung-Teh, Porton, Barbara, Marsella, Sarah A., Carpenter, Linda L.
Published in Biological psychiatry (1969) (15.03.2010)
Published in Biological psychiatry (1969) (15.03.2010)
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A Senescent Cluster in Aged Human Hematopoietic Stem Cell Compartment as Target for Senotherapy
Poisa-Beiro, Laura, Landry, Jonathan J. M., Yan, Bowen, Kardorff, Michael, Eckstein, Volker, Villacorta, Laura, Krammer, Peter H., Zaugg, Judith, Gavin, Anne-Claude, Benes, Vladimir, Zhou, Daohong, Raffel, Simon, Ho, Anthony D.
Published in International journal of molecular sciences (17.01.2025)
Published in International journal of molecular sciences (17.01.2025)
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LEF1 isoforms regulate cellular senescence and aging
Jia, Minxue, Sayed, Khaled, Kapetanaki, Maria G., Dion, William, Rosas, Lorena, Irfan, Saad, Valenzi, Eleanor, Mora, Ana L., Lafyatis, Robert A., Rojas, Mauricio, Zhu, Bokai, Benos, Panayiotis V.
Published in Aging cell (01.12.2023)
Published in Aging cell (01.12.2023)
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Increased cellular senescence in the murine and human stenotic kidney: Effect of mesenchymal stem cells
Kim, Seo Rin, Zou, Xiangyu, Tang, Hui, Puranik, Amrutesh S., Abumoawad, Abdelrhman M., Zhu, Xiang‐Yang, Hickson, LaTonya J., Tchkonia, Tamara, Textor, Stephen C., Kirkland, James L., Lerman, Lilach O.
Published in Journal of cellular physiology (01.02.2021)
Published in Journal of cellular physiology (01.02.2021)
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Transcriptomics Analysis Identifies the Decline in the Alveolar Type II Stem Cell Niche in Aged Human Lungs
Liu, Xue, Zhang, Xuexi, Yao, Changfu, Liang, Jiurong, Noble, Paul W., Jiang, Dianhua
Published in American journal of respiratory cell and molecular biology (01.08.2024)
Published in American journal of respiratory cell and molecular biology (01.08.2024)
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Downregulation of PLIN2 in human dermal fibroblasts impairs mitochondrial function in an age‐dependent fashion and induces cell senescence via GDF15
Chiariello, Antonio, Rossetti, Luca, Valente, Sabrina, Pasquinelli, Gianandrea, Sollazzo, Manuela, Iommarini, Luisa, Porcelli, Anna Maria, Tognocchi, Monica, Conte, Giuseppe, Santoro, Aurelia, Kwiatkowska, Katarzyna M., Garagnani, Paolo, Salvioli, Stefano, Conte, Maria
Published in Aging cell (01.05.2024)
Published in Aging cell (01.05.2024)
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Germline Mutations in Oncogene-Induced Senescence Pathways Are Associated With Multiple Sessile Serrated Adenomas
Gala, Manish K., Mizukami, Yusuke, Le, Long P., Moriichi, Kentaro, Austin, Thomas, Yamamoto, Masayoshi, Lauwers, Gregory Y., Bardeesy, Nabeel, Chung, Daniel C.
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2014)
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2014)
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TRIM22 induces cellular senescence by targeting PHLPP2 in hepatocellular carcinoma
Kang, Donghee, Hwang, Hyun Jung, Baek, Yurim, Sung, Jee Young, Kim, KyeongJin, Park, Heon Joo, Ko, Young-Gyu, Kim, Yong-Nyun, Lee, Jae-Seon
Published in Cell death & disease (10.01.2024)
Published in Cell death & disease (10.01.2024)
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