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Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Attachment. 5. An Evolution from Indole to Azaindoles Leading to the Discovery of 1-(4-Benzoylpiperazin-1-yl)-2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-488043), a Drug Candidate That Demonstrates Antiviral Activity in HIV-1-Infected Subjects
Wang, Tao, Yin, Zhiwei, Zhang, Zhongxing, Bender, John A, Yang, Zhong, Johnson, Graham, Yang, Zheng, Zadjura, Lisa M, D’Arienzo, Celia J, DiGiugno Parker, Dawn, Gesenberg, Christophe, Yamanaka, Gregory A, Gong, Yi-Fei, Ho, Hsu-Tso, Fang, Hua, Zhou, Nannan, McAuliffe, Brian V, Eggers, Betsy J, Fan, Li, Nowicka-Sans, Beata, Dicker, Ira B, Gao, Qi, Colonno, Richard J, Lin, Pin-Fang, Meanwell, Nicholas A, Kadow, John F
Published in Journal of medicinal chemistry (10.12.2009)
Published in Journal of medicinal chemistry (10.12.2009)
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Establishment and characterization of a novel primary hepatocellular carcinoma cell line with metastatic ability in vivo
Cheung, Phyllis Fung-Yi, Yip, Chi Wai, Ng, Linda Wing-Chi, Lo, Kwok Wai, Wong, Nathalie, Choy, Kwong Wai, Chow, Chit, Chan, Kui Fat, Cheung, Tan To, Poon, Ronnie Tung-Ping, Fan, Sheung Tat, Cheung, Siu Tim
Published in Cancer cell international (09.10.2014)
Published in Cancer cell international (09.10.2014)
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DNA polymerase zeta contributes to heterochromatin replication to prevent genome instability
Ben Yamin, Barbara, Ahmed‐Seghir, Sana, Tomida, Junya, Despras, Emmanuelle, Pouvelle, Caroline, Yurchenko, Andrey, Goulas, Jordane, Corre, Raphael, Delacour, Quentin, Droin, Nathalie, Dessen, Philippe, Goidin, Didier, Lange, Sabine S, Bhetawal, Sarita, Mitjavila‐Garcia, Maria Teresa, Baldacci, Giuseppe, Nikolaev, Sergey, Cadoret, Jean Charles, Wood, Richard D, Kannouche, Patricia L
Published in The EMBO journal (02.11.2021)
Published in The EMBO journal (02.11.2021)
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Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase
Baltgalvis, Kristen A., Lamb, Kelsey N., Symons, Kent T., Wu, Chu-Chiao, Hoffman, Melissa A., Snead, Aaron N., Song, Xiaodan, Glaza, Thomas, Kikuchi, Shota, Green, Jason C., Rogness, Donald C., Lam, Betty, Rodriguez-Aguirre, Maria E., Woody, David R., Eissler, Christie L., Rodiles, Socorro, Negron, Seth M., Bernard, Steffen M., Tran, Eileen, Pollock, Jonathan, Tabatabaei, Ali, Contreras, Victor, Williams, Heather N., Pastuszka, Martha K., Sigler, John J., Pettazzoni, Piergiorgio, Rudolph, Markus G., Classen, Moritz, Brugger, Doris, Claiborne, Christopher, Plancher, Jean-Marc, Cuartas, Isabel, Seoane, Joan, Burgess, Laurence E., Abraham, Robert T., Weinstein, David S., Simon, Gabriel M., Patricelli, Matthew P., Kinsella, Todd M.
Published in Nature (London) (09.05.2024)
Published in Nature (London) (09.05.2024)
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Drug-Based Lead Discovery: The Novel Ablative Antiretroviral Profile of Deferiprone in HIV-1-Infected Cells and in HIV-Infected Treatment-Naive Subjects of a Double-Blind, Placebo-Controlled, Randomized Exploratory Trial
Saxena, Deepti, Spino, Michael, Tricta, Fernando, Connelly, John, Cracchiolo, Bernadette M., Hanauske, Axel-Rainer, D’Alliessi Gandolfi, Darlene, Mathews, Michael B., Karn, Jonathan, Holland, Bart, Park, Myung Hee, Pe’ery, Tsafi, Palumbo, Paul E., Hanauske-Abel, Hartmut M.
Published in PloS one (18.05.2016)
Published in PloS one (18.05.2016)
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Methoxyamine sensitizes the resistant glioblastoma T98G cell line to the alkylating agent temozolomide
Montaldi, Ana P., Sakamoto-Hojo, Elza T.
Published in Clinical and experimental medicine (01.11.2013)
Published in Clinical and experimental medicine (01.11.2013)
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Genetic variation in a human odorant receptor alters odour perception
Keller, Andreas, Zhuang, Hanyi, Chi, Qiuyi, Vosshall, Leslie B., Matsunami, Hiroaki
Published in Nature (27.09.2007)
Published in Nature (27.09.2007)
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Ribosomal protein RPL26 is the principal target of UFMylation
Walczak, Christopher P., Leto, Dara E., Zhang, Lichao, Riepe, Celeste, Muller, Ryan Y., DaRosa, Paul A., Ingolia, Nicholas T., Elias, Joshua E., Kopito, Ron R.
Published in Proceedings of the National Academy of Sciences - PNAS (22.01.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (22.01.2019)
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IL-17A enhances IL-13 activity by enhancing IL-13–induced signal transducer and activator of transcription 6 activation
Hall, Sara L., Baker, Theresa, Lajoie, Stephane, Richgels, Phoebe K., Yang, Yanfen, McAlees, Jaclyn W., van Lier, Adelaide, Wills-Karp, Marsha, Sivaprasad, Umasundari, Acciani, Thomas H., LeCras, Timothy D., Myers, Jocelyn Biagini, Kovacic, Melinda Butsch, Lewkowich, Ian P.
Published in Journal of allergy and clinical immunology (01.02.2017)
Published in Journal of allergy and clinical immunology (01.02.2017)
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The MUC5B-associated variant rs35705950 resides within an enhancer subject to lineage- and disease-dependent epigenetic remodeling
Gally, Fabienne, Sasse, Sarah K., Kurche, Jonathan S., Gruca, Margaret A., Cardwell, Jonathan H., Okamoto, Tsukasa, Chu, Hong W., Hou, Xiaomeng, Poirion, Olivier B., Buchanan, Justin, Preissl, Sebastian, Ren, Bing, Colgan, Sean P., Dowell, Robin D., Yang, Ivana V., Schwartz, David A., Gerber, Anthony N.
Published in JCI insight (25.01.2021)
Published in JCI insight (25.01.2021)
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3,5,3′-Triiodo-L-thyronine enhances the differentiation of a human pancreatic duct cell line (hPANC-1) towards a β-cell-Like phenotype
Misiti, Silvia, Anastasi, Emanuela, Sciacchitano, Salvatore, Verga Falzacappa, Cecilia, Panacchia, Laura, Bucci, Barbara, Khouri, Daniele, D'Acquarica, Ilaria, Brunetti, Ercole, Di Mario, Umberto, Toscano, Vincenzo, Perfetti, Riccardo
Published in Journal of cellular physiology (01.07.2005)
Published in Journal of cellular physiology (01.07.2005)
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Abstract P5-04-02: Safety and efficacy from first-in-human immunotherapy combining NK and T cell activation with off-the-shelf high-affinity CD16 NK cell line (haNK) in patients with 2nd-line or greater metastatic triple-negative breast cancer (TNBC)
Kistler, Mira, Nangia, Chaitali, To, Christina, Sender, Lennie, Lee, John, Jones, Frank, Jafari, Omid, Seery, Tara, Rabizadeh, Shahrooz, Niazi, Kayvan, Rock, Amy, Soon-Shiong, Patrick
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Addiction associated N40D mu-opioid receptor variant modulates synaptic function in human neurons
Halikere, Apoorva, Popova, Dina, Scarnati, Matthew S., Hamod, Aula, Swerdel, Mavis R., Moore, Jennifer C., Tischfield, Jay A., Hart, Ronald P., Pang, Zhiping P.
Published in Molecular psychiatry (01.07.2020)
Published in Molecular psychiatry (01.07.2020)
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Glial Cell-Line Derived Neurotrophic Factor (GDNF) Concentrations in Cerebrospinal Fluid and Serum of Patients with Early Alzheimer's Disease and Normal Controls
Straten, Guido, Eschweiler, Gerhard W., Maetzler, Walter, Laske, Christoph, Leyhe, Thomas
Published in Journal of Alzheimer's disease (01.01.2009)
Published in Journal of Alzheimer's disease (01.01.2009)
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Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity
Al-dulaimi, Sarah, Thomas, Ross, Matta, Sheila, Roberts, Terry
Published in Biogerontology (Dordrecht) (04.09.2025)
Published in Biogerontology (Dordrecht) (04.09.2025)
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ISG15 targets glycosylated PD-L1 and promotes its degradation to enhance antitumor immune effects in lung adenocarcinoma
Qu, Tongyuan, Zhang, Wenshuai, Yan, Chenhui, Ren, Danyang, Wang, Yalei, Guo, Yuhong, Guo, Qianru, Wang, Jinpeng, Liu, Liren, Han, Lei, Li, Lingmei, Huang, Qiujuan, Cao, Lu, Ye, Zhaoxiang, Zhang, Bin, Zhao, Qiang, Cao, Wenfeng
Published in Journal of translational medicine (22.05.2023)
Published in Journal of translational medicine (22.05.2023)
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WISH cell line: From the antiviral system to a novel reporter gene assay to test the potency of human IFN-α and IFN-β
Bürgi, María de los Milagros, Prieto, Claudio, Etcheverrigaray, Marina, Kratje, Ricardo, Oggero, Marcos, Bollati-Fogolín, Mariela
Published in Journal of immunological methods (31.07.2012)
Published in Journal of immunological methods (31.07.2012)
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