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Ortega-Molina, Ana, Lopez-Guadamillas, Elena, Mattison, Julie A., Mitchell, Sarah J., Muñoz-Martin, Maribel, Iglesias, Gema, Gutierrez, Vincent M., Vaughan, Kelli L., Szarowicz, Mark D., González-García, Ismael, López, Miguel, Cebrián, David, Martinez, Sonia, Pastor, Joaquin, de Cabo, Rafael, Serrano, Manuel
Published in Cell metabolism (07.04.2015)
Published in Cell metabolism (07.04.2015)
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Omipalisib inspired macrocycles as dual PI3K/mTOR inhibitors
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Published in European journal of medicinal chemistry (05.02.2021)
Published in European journal of medicinal chemistry (05.02.2021)
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GDPRValidator: a tool to enable companies using cloud services to be GDPR compliant
Cambronero, M Emilia, Martínez, Miguel A, de la Vara, José Luis, Cebrián, David, Valero, Valentín
Published in PeerJ. Computer science (01.12.2022)
Published in PeerJ. Computer science (01.12.2022)
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Discovery of novel triazolo[4,3-b]pyridazin-3-yl-quinoline derivatives as PIM inhibitors
Martínez-González, Sonia, Rodríguez-Arístegui, Sonsoles, Gómez de la Oliva, Cristina Ana, Hernández, Ana Isabel, González Cantalapiedra, Esther, Varela, Carmen, García, Ana Belén, Rabal, Obdulia, Oyarzabal, Julen, Bischoff, James R., Klett, Javier, Albarrán, María Isabel, Cebriá, Antonio, Ajenjo, Nuria, García-Serelde, Beatriz, Gómez-Casero, Elena, Cuadrado-Urbano, Manuel, Cebrián, David, Blanco-Aparicio, Carmen, Pastor, Joaquín
Published in European journal of medicinal chemistry (15.04.2019)
Published in European journal of medicinal chemistry (15.04.2019)
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Comparing the influence of two immunosuppressants (fingolimod, azathioprine) on wound healing in a rat model of primary and secondary intention wound closure
Ginestal, Ricardo, Pérez‐Köhler, Bárbara, Pérez‐López, Paloma, Rodríguez, Marta, Pascual, Gemma, Cebrián, David, Bellón, Juan M., García‐Moreno, Francisca
Published in Wound repair and regeneration (01.01.2019)
Published in Wound repair and regeneration (01.01.2019)
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Generation of tricyclic imidazo[1,2-a]pyrazines as novel PI3K inhibitors by application of a conformational restriction strategy
Martínez González, Sonia, Rodríguez-Arístegui, Sonsoles, Hernández, Ana Isabel, Varela, Carmen, González Cantalapiedra, Esther, Álvarez, Rosa María, Rodríguez Hergueta, Antonio, Bischoff, James R., Albarrán, María Isabel, Cebriá, Antonio, Cendón, Elena, Cebrián, David, Alfonso, Patricia, Pastor, Joaquín
Published in Bioorganic & medicinal chemistry letters (01.06.2017)
Published in Bioorganic & medicinal chemistry letters (01.06.2017)
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Hit to lead evaluation of 1,2,3-triazolo[4,5-b]pyridines as PIM kinase inhibitors
Pastor, Joaquín, Oyarzabal, Julen, Saluste, Gustavo, Alvarez, Rosa María, Rivero, Virginia, Ramos, Francisco, Cendón, Elena, Blanco-Aparicio, Carmen, Ajenjo, Nuria, Cebriá, Antonio, Albarrán, M.I., Cebrián, David, Corrionero, Ana, Fominaya, Jesús, Montoya, Guillermo, Mazzorana, Marco
Published in Bioorganic & medicinal chemistry letters (15.02.2012)
Published in Bioorganic & medicinal chemistry letters (15.02.2012)
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Identification of ETP-46321, a potent and orally bioavailable PI3K α, δ inhibitor
Martínez González, Sonia, Hernández, Ana Isabel, Varela, Carmen, Rodríguez-Arístegui, Sonsoles, Lorenzo, Milagros, Rodríguez, Antonio, Rivero, Virginia, Martín, José Ignacio, Saluste, Carl Gustav, Ramos-Lima, Francisco, Cendón, Elena, Cebrián, David, Aguirre, Enara, Gomez-Casero, Elena, Albarrán, Maribel, Alfonso, Patricia, García-Serelde, Beatriz, Oyarzabal, Julen, Rabal, Obdulia, Mulero, Francisca, Gonzalez-Granda, Teresa, Link, Wolfgang, Fominaya, Jesús, Barbacid, Mariano, Bischoff, James R., Pizcueta, Pilar, Pastor, Joaquín
Published in Bioorganic & medicinal chemistry letters (15.05.2012)
Published in Bioorganic & medicinal chemistry letters (15.05.2012)
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Nodal/Activin Signaling Drives Self-Renewal and Tumorigenicity of Pancreatic Cancer Stem Cells and Provides a Target for Combined Drug Therapy
Lonardo, Enza, Hermann, Patrick C., Mueller, Maria-Theresa, Huber, Stephan, Balic, Anamaria, Miranda-Lorenzo, Irene, Zagorac, Sladjana, Alcala, Sonia, Rodriguez-Arabaolaza, Iker, Ramirez, Juan Carlos, Torres-Ruíz, Raul, Garcia, Elena, Hidalgo, Manuel, Cebrián, David Álvaro, Heuchel, Rainer, Löhr, Matthias, Berger, Frank, Bartenstein, Peter, Aicher, Alexandra, Heeschen, Christopher
Published in Cell stem cell (04.11.2011)
Published in Cell stem cell (04.11.2011)
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Automated design of customized implants
Chulvi, Vicente, Cebrian Tarrasón, David, Sancho, Álex, Vidal, Rosario
Published in Revista Facultad de Ingeniería (01.09.2013)
Published in Revista Facultad de Ingeniería (01.09.2013)
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Rapid identification of ETP-46992, orally bioavailable PI3K inhibitor, selective versus mTOR
Martínez González, Sonia, Hernández, Ana Isabel, Varela, Carmen, Lorenzo, Milagros, Ramos-Lima, Francisco, Cendón, Elena, Cebrián, David, Aguirre, Enara, Gomez-Casero, Elena, Albarrán, M.I., Alfonso, Patricia, García-Serelde, Beatriz, Mateos, Genoveva, Oyarzabal, Julen, Rabal, Obdulia, Mulero, Francisca, Gonzalez-Granda, Teresa, Link, Wolfgang, Fominaya, Jesús, Barbacid, Mariano, Bischoff, James R., Pizcueta, Pilar, Blanco-Aparicio, Carmen, Pastor, Joaquín
Published in Bioorganic & medicinal chemistry letters (15.08.2012)
Published in Bioorganic & medicinal chemistry letters (15.08.2012)
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Biological characterization of ETP-46321 a selective and efficacious inhibitor of phosphoinositide-3-kinases
Granda, Teresa G., Cebrián, David, Martínez, Sonia, Anguita, Patricia Villanueva, López, Estela Casas, Link, Wolfgang, Merino, Teresa, Pastor, Joaquín, Serelde, Beatriz G., Peregrina, Sandra, Palacios, Irene, Albarran, Maria Isabel, Cebriá, Antonio, Lorenzo, Milagros, Alonso, Patricia, Fominaya, Jesús, López, Ana Rodríguez, Bischoff, James R.
Published in Investigational new drugs (01.02.2013)
Published in Investigational new drugs (01.02.2013)
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Macrocyclization as a Source of Desired Polypharmacology. Discovery of Triple PI3K/mTOR/PIM Inhibitors
Martínez-González, Sonia, Alvarez, Rosa M, Martín, José I, García, Ana Belén, Riesco-Fagundo, Concepción, Varela, Carmen, Rodríguez Hergueta, Antonio, González Cantalapiedra, Esther, Albarrán, M. I, Gómez-Casero, Elena, Cebriá, Antonio, Aguirre, Enara, Ajenjo, Nuria, Cebrián, David, Di Geronimo, Bruno, Cunningham, Darren, O’Neill, Michael, Dave, Harish P. G, Blanco-Aparicio, Carmen, Pastor, Joaquín
Published in ACS medicinal chemistry letters (11.11.2021)
Published in ACS medicinal chemistry letters (11.11.2021)
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Identification of novel PI3K inhibitors through a scaffold hopping strategy
Martínez González, Sonia, Hernández, Ana Isabel, Álvarez, Rosa María, Rodríguez, Antonio, Ramos-Lima, Francisco, Bischoff, James R., Albarrán, María Isabel, Cebriá, Antonio, Hernández-Encinas, Elena, García-Arocha, Jennifer, Cebrián, David, Blanco-Aparicio, Carmen, Pastor, Joaquín
Published in Bioorganic & medicinal chemistry letters (01.11.2017)
Published in Bioorganic & medicinal chemistry letters (01.11.2017)
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Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition
Wyllie, Susan, Brand, Stephen, Thomas, Michael, De Rycker, Manu, Chung, Chun-wa, Pena, Imanol, Bingham, Ryan P., Bueren-Calabuig, Juan A., Cantizani, Juan, Cebrian, David, Craggs, Peter D., Ferguson, Liam, Goswami, Panchali, Hobrath, Judith, Howe, Jonathan, Jeacock, Laura, Ko, Eun-Jung, Korczynska, Justyna, MacLean, Lorna, Manthri, Sujatha, Martinez, Maria S., Mata-Cantero, Lydia, Moniz, Sonia, Nühs, Andrea, Osuna-Cabello, Maria, Pinto, Erika, Riley, Jennifer, Robinson, Sharon, Rowland, Paul, Simeons, Frederick R. C., Shishikura, Yoko, Spinks, Daniel, Stojanovski, Laste, Thomas, John, Thompson, Stephen, Gaza, Elisabet Viayna, Wall, Richard J., Zuccotto, Fabio, Horn, David, Ferguson, Michael A. J., Fairlamb, Alan H., Fiandor, Jose M., Martin, Julio, Gray, David W., Miles, Timothy J., Gilbert, Ian H., Read, Kevin D., Marco, Maria, Wyatt, Paul G.
Published in Proceedings of the National Academy of Sciences - PNAS (07.05.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (07.05.2019)
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Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism
MacLeod, A Kenneth, Coquelin, Kevin-Sebastien, Huertas, Leticia, Simeons, Frederick R C, Riley, Jennifer, Casado, Patricia, Guijarro, Laura, Casanueva, Ruth, Frame, Laura, Pinto, Erika G, Ferguson, Liam, Duncan, Christina, Mutter, Nicole, Shishikura, Yoko, Henderson, Colin J, Cebrian, David, Wolf, C Roland, Read, Kevin D
Published in Proceedings of the National Academy of Sciences - PNAS (13.02.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (13.02.2024)
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Paradoxical EU agricultural policies on genetically engineered crops
Masip, Gemma, Sabalza, Maite, Pérez-Massot, Eduard, Banakar, Raviraj, Cebrian, David, Twyman, Richard M, Capell, Teresa, Albajes, Ramon, Christou, Paul
Published in Trends in plant science (01.06.2013)
Published in Trends in plant science (01.06.2013)
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Current Approaches for Predicting Human PK for Small Molecule Development Candidates: Findings from the IQ Human PK Prediction Working Group Survey
Petersson, Carl, Zhou, Xin, Berghausen, Joerg, Cebrian, David, Davies, Michael, DeMent, Kevin, Eddershaw, Peter, Riedmaier, Arian Emami, Leblanc, Alix F., Manveski, Nenad, Marathe, Punit, Mavroudis, Panteleimon D., McDougall, Robin, Parrott, Neil, Reichel, Andreas, Rotter, Charles, Tess, David, Volak, Laurie P., Xiao, Guangqing, Yang, Zheng, Baker, James
Published in The AAPS journal (19.07.2022)
Published in The AAPS journal (19.07.2022)
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