Making Better Drugs: Decision Gates in Non-Clinical Drug Development
Pritchard, J. Fred, Jurima-Romet, Malle, Reimer, Mark L. J, Mortimer, Elisabeth, Rolfe, Brenda, Cayen, Mitchell N
Published in Nature reviews. Drug discovery (01.07.2003)
Published in Nature reviews. Drug discovery (01.07.2003)
Get full text
Journal Article
Disposition of the Selective Cholesterol Absorption Inhibitor Ezetimibe in Healthy Male Subjects
PATRICK, James E, KOSOGLOU, Teddy, CAYEN, Mitchell N, STAUBER, Kathe L, ALTON, Kevin B, MAXWELL, Stephen E, YALI ZHU, STATKEVICH, Paul, IANNUCCI, Robert, CHOWDHURY, Swapan, AFFRIME, Melton
Published in Drug metabolism and disposition (01.04.2002)
Published in Drug metabolism and disposition (01.04.2002)
Get full text
Journal Article
Pharmacokinetics of SCH 56592, a New Azole Broad-Spectrum Antifungal Agent, in Mice, Rats, Rabbits, Dogs, and Cynomolgus Monkeys
NOMEIR, A. A, KUMARI, P, HILBERT, M. J, GUPTA, S, LOEBENBERG, D, CACCIAPUOTI, A, HARE, R, MILLER, G. H, LIN, C.-C, CAYEN, M. N
Published in Antimicrobial Agents and Chemotherapy (01.03.2000)
Published in Antimicrobial Agents and Chemotherapy (01.03.2000)
Get full text
Journal Article
Drug Metabolites in Safety Testing
Baillie, Thomas A., Cayen, Mitchell N., Fouda, Hassan, Gerson, Ronald J., Green, James D., Grossman, Scott J., Klunk, Lewis J., LeBlanc, Bernard, Perkins, Darcy G., Shipley, Lisa A.
Published in Toxicology and applied pharmacology (01.08.2002)
Published in Toxicology and applied pharmacology (01.08.2002)
Get full text
Journal Article
The Penetration of Ceftibuten Into the Respiratory Tract
Krumpe, Peter, Lin, Chin-Chung, Radwanski, Elaine, Cayen, Mitchell N., Affrime, Melton B.
Published in Chest (01.08.1999)
Published in Chest (01.08.1999)
Get full text
Journal Article
In Vitro Uptake of SCH 27899 (Evernimicin) by Rat Alveolar Macrophages
ZBAIDA, Shmuel, BRIELAND, Joan, PATRICK, James E, KRIETER, Philip, LOEBENBERG, David, KRISHNA, Gopal, HORNE, Debra, LU, Xiaowen, YUAN YUAN, HARE, Roberta, CAYEN, Mitchell N
Published in Antimicrobial Agents and Chemotherapy (01.03.2001)
Published in Antimicrobial Agents and Chemotherapy (01.03.2001)
Get full text
Journal Article
Bioavailability and metabolism of mometasone furoate following administration by metered-dose and dry-powder inhalers in healthy human volunteers
Affrime, M B, Cuss, F, Padhi, D, Wirth, M, Pai, S, Clement, R P, Lim, J, Kantesaria, B, Alton, K, Cayen, M N
Published in Journal of clinical pharmacology (01.11.2000)
Published in Journal of clinical pharmacology (01.11.2000)
Get more information
Journal Article
Characterization of AUCs from sparsely sampled populations in toxicology studies
Pai, S M, Fettner, S H, Hajian, G, Cayen, M N, Batra, V K
Published in Pharmaceutical research (01.09.1996)
Published in Pharmaceutical research (01.09.1996)
Get more information
Journal Article
Synthesis and antihypertensive activity of some thienylethanolamines
Bagli, Jehan F, Mackay, Walter D, Ferdinandi, Eckhardt, Cayen, Mitchell N, Vavra, Ivan, Pugsley, Thomas, Lippmann, Wilbur
Published in Journal of medicinal chemistry (01.07.1976)
Published in Journal of medicinal chemistry (01.07.1976)
Get full text
Journal Article
Pharmacokinetics and disposition of the lipid-lowering drug acifran in normal subjects and in patients with renal failure
Cayen, M N, Ferdinandi, E S, Hicks, D R, Gonzalez, R, Cosyns, L, Dubuc, J, Kraml, M, Edwards, K D
Published in Clinical pharmacology and therapeutics (01.01.1990)
Published in Clinical pharmacology and therapeutics (01.01.1990)
Get more information
Journal Article
The metabolic disposition of etodolac in rats, dogs, and man
Cayen, M N, Kraml, M, Ferdinandi, E S, Greselin, E, Dvornik, D
Published in Drug metabolism reviews (1981)
Published in Drug metabolism reviews (1981)
Get more information
Journal Article
TOXICOKINETICS:ITS SIGNIFICANCE AND PRACTICAL PROBLEMS
KATO, Ryuichi, CASE, David E., HAKUSUI, Hideo, NODA, Kosei, SAGAMI, Fumio, HORII, Ikuo, MAYAHARA, Hiroshi, CAYEN, Mitchell N., MARRIOTT, Thomas B., IGARASHI, Toshiji
Published in Journal of toxicological sciences (1993)
Published in Journal of toxicological sciences (1993)
Get full text
Journal Article
Conference Proceeding
Tolrestat kinetics
Hicks, D R, Kraml, M, Cayen, M N, Dubuc, J, Ryder, S, Dvornik, D
Published in Clinical pharmacology and therapeutics (01.10.1984)
Published in Clinical pharmacology and therapeutics (01.10.1984)
Get more information
Journal Article
Studies on the disposition of diosgenin in rats, dogs, monkeys and man
Cayen, Mitchell N., Ferdinandi, Eckhardt S., Greselin, Erminio, Dvornik, Dushan
Published in Atherosclerosis (01.05.1979)
Published in Atherosclerosis (01.05.1979)
Get full text
Journal Article
Novel in vivo procedure for rapid pharmacokinetic screening of discovery compounds in rats
Cox, Kathleen A., Dunn-Meynell, Kimberly, Korfmacher, Walter A., Broske, Lisa, Nomeir, Amin A., Lin, Chin-Chung, Cayen, Mitchell N., Barr, William H.
Published in Drug Discovery Today (01.05.1999)
Published in Drug Discovery Today (01.05.1999)
Get full text
Book Review
Journal Article