N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis
Karmakar, Mausita, Minns, Martin, Greenberg, Elyse N., Diaz-Aponte, Jose, Pestonjamasp, Kersi, Johnson, Jennifer L., Rathkey, Joseph K., Abbott, Derek W., Wang, Kun, Shao, Feng, Catz, Sergio D., Dubyak, George R., Pearlman, Eric
Published in Nature communications (05.05.2020)
Published in Nature communications (05.05.2020)
Get full text
Journal Article
Neutrophils: New insights and open questions
Ley, Klaus, Hoffman, Hal M, Kubes, Paul, Cassatella, Marco A, Zychlinsky, Arturo, Hedrick, Catherine C, Catz, Sergio D
Published in Science immunology (14.12.2018)
Published in Science immunology (14.12.2018)
Get more information
Journal Article
Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells
Rega, Laura R., Polishchuk, Elena, Montefusco, Sandro, Napolitano, Gennaro, Tozzi, Giulia, Zhang, Jinzhong, Bellomo, Francesco, Taranta, Anna, Pastore, Anna, Polishchuk, Roman, Piemonte, Fiorella, Medina, Diego L., Catz, Sergio D., Ballabio, Andrea, Emma, Francesco
Published in Kidney international (01.04.2016)
Published in Kidney international (01.04.2016)
Get full text
Journal Article
Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A
Zhang, Jinzhong, Johnson, Jennifer L., He, Jing, Napolitano, Gennaro, Ramadass, Mahalakshmi, Rocca, Celine, Kiosses, William B., Bucci, Cecilia, Xin, Qisheng, Gavathiotis, Evripidis, Cuervo, Ana María, Cherqui, Stephanie, Catz, Sergio D.
Published in The Journal of biological chemistry (23.06.2017)
Published in The Journal of biological chemistry (23.06.2017)
Get full text
Journal Article
Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Gem-interacting protein
Johnson, Jennifer L, Monfregola, Jlenia, Napolitano, Gennaro, Kiosses, William B, Catz, Sergio D
Published in Molecular biology of the cell (15.05.2012)
Published in Molecular biology of the cell (15.05.2012)
Get full text
Journal Article
Cross-regulation of defective endolysosome trafficking and enhanced autophagy through TFEB in UNC13D deficiency
Zhang, Jinzhong, He, Jing, Johnson, Jennifer L., Napolitano, Gennaro, Ramadass, Mahalakshmi, Rahman, Farhana, Catz, Sergio D.
Published in Autophagy (03.10.2019)
Published in Autophagy (03.10.2019)
Get full text
Journal Article
Src family kinase-mediated vesicle trafficking is critical for neutrophil basement membrane penetration
Rohwedder, Ina, Kurz, Angela R M, Pruenster, Monika, Immler, Roland, Pick, Robert, Eggersmann, Tanja, Klapproth, Sarah, Johnson, Jennifer L, Alsina, Sergi Masgrau, Lowell, Clifford A, Mócsai, Attila, Catz, Sergio D, Sperandio, Markus
Published in Haematologica (Roma) (01.07.2020)
Published in Haematologica (Roma) (01.07.2020)
Get full text
Journal Article
Interaction between galectin-3 and cystinosin uncovers a pathogenic role of inflammation in kidney involvement of cystinosis
Lobry, Tatiana, Miller, Roy, Nevo, Nathalie, Rocca, Celine J., Zhang, Jinzhong, Catz, Sergio D., Moore, Fiona, Thomas, Lucie, Pouly, Daniel, Bailleux, Anne, Guerrera, Ida Chiara, Gubler, Marie-Claire, Cheung, Wai W., Mak, Robert H., Montier, Tristan, Antignac, Corinne, Cherqui, Stephanie
Published in Kidney international (01.08.2019)
Published in Kidney international (01.08.2019)
Get full text
Journal Article
Impairment of chaperone‐mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis
Napolitano, Gennaro, Johnson, Jennifer L, He, Jing, Rocca, Celine J, Monfregola, Jlenia, Pestonjamasp, Kersi, Cherqui, Stephanie, Catz, Sergio D
Published in EMBO molecular medicine (01.02.2015)
Published in EMBO molecular medicine (01.02.2015)
Get full text
Journal Article
Defective endomembrane dynamics in Rab27a deficiency impairs nucleic acid sensing and cytokine secretion in immune cells
Yu, Juan, Meneses-Salas, Elsa, Johnson, Jennifer L., Manenti, Susanna, Kbaich, Mouad Ait, Chen, Danni, Askari, Kasra, He, Jing, Shukla, Aparna, Shaji, Binchu, Gonzalez-Quintial, Rosana, Croker, Ben A., Zhang, Jinzhong, Hoffman, Hal, Kiosses, William B., Hedrick, Catherine, Pestonjamasp, Kersi, Wineinger, Nathan, Baccala, Roberto, Catz, Sergio D.
Published in Cell reports (Cambridge) (27.08.2024)
Published in Cell reports (Cambridge) (27.08.2024)
Get full text
Journal Article
Aberrant autolysosomal regulation is linked to the induction of embryonic senescence: differential roles of Beclin 1 and p53 in vertebrate Spns1 deficiency
Sasaki, Tomoyuki, Lian, Shanshan, Qi, Jie, Bayliss, Peter E, Carr, Christopher E, Johnson, Jennifer L, Guha, Sujay, Kobler, Patrick, Catz, Sergio D, Gill, Matthew, Jia, Kailiang, Klionsky, Daniel J, Kishi, Shuji
Published in PLoS genetics (01.06.2014)
Published in PLoS genetics (01.06.2014)
Get full text
Journal Article
Upregulation of the Rab27a-Dependent Trafficking and Secretory Mechanisms Improves Lysosomal Transport, Alleviates Endoplasmic Reticulum Stress, and Reduces Lysosome Overload in Cystinosis
Johnson, Jennifer L., Napolitano, Gennaro, Monfregola, Jlenia, Rocca, Celine J., Cherqui, Stephanie, Catz, Sergio D.
Published in Molecular and Cellular Biology (01.08.2013)
Published in Molecular and Cellular Biology (01.08.2013)
Get full text
Journal Article
Differential dysregulation of granule subsets in WASH-deficient neutrophil leukocytes resulting in inflammation
Johnson, Jennifer L., Meneses-Salas, Elsa, Ramadass, Mahalakshmi, Monfregola, Jlenia, Rahman, Farhana, Carvalho Gontijo, Raquel, Kiosses, William B., Pestonjamasp, Kersi, Allen, Dale, Zhang, Jinzhong, Osborne, Douglas G., Zhu, Yanfang Peipei, Wineinger, Nathan, Askari, Kasra, Chen, Danni, Yu, Juan, Henderson, Scott C., Hedrick, Catherine C., Ursini, Matilde Valeria, Grinstein, Sergio, Billadeau, Daniel D., Catz, Sergio D.
Published in Nature communications (21.09.2022)
Published in Nature communications (21.09.2022)
Get full text
Journal Article
Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation
Walpole, Glenn F.W., Plumb, Jonathan D., Chung, Daniel, Tang, Brandon, Boulay, Benoit, Osborne, Douglas G., Piotrowski, Joshua T., Catz, Sergio D., Billadeau, Daniel D., Grinstein, Sergio, Jaumouillé, Valentin
Published in Cell reports (Cambridge) (02.06.2020)
Published in Cell reports (Cambridge) (02.06.2020)
Get full text
Journal Article
Distinct and opposing roles for Rab27a/Mlph/MyoVa and Rab27b/Munc13‐4 in mast cell secretion
Singh, Rajesh K., Mizuno, Koichi, Wasmeier, Christina, Wavre‐Shapton, Silene T., Recchi, Chiara, Catz, Sergio D., Futter, Clare, Tolmachova, Tanya, Hume, Alistair N., Seabra, Miguel C.
Published in The FEBS journal (01.02.2013)
Published in The FEBS journal (01.02.2013)
Get full text
Journal Article
Increased Survival and Reduced Neutrophil Infiltration of the Liver in Rab27a- but Not Munc13-4-Deficient Mice in Lipopolysaccharide-Induced Systemic Inflammation
JOHNSON, Jennifer L, HONG HONG, MONFREGOLA, Jlenia, CATZ, Sergio D
Published in Infection and Immunity (01.09.2011)
Published in Infection and Immunity (01.09.2011)
Get full text
Journal Article
Human CD79b + neutrophils in the blood are associated with early-stage melanoma
Meyer, Melissa A, Dinh, Huy Q, Alimadadi, Ahmad, Araujo, Daniel J, Chatterjee, Nandini, Gutierrez, Norma A, Zhu, Yanfang Peipei, Hunter, Emma L, Liang, Shu, Seumois, Gregory, Kiosses, William B, Catz, Sergio D, Vijayanand, Pandurangan, Ottensmeier, Christian, Hedrick, Catherine C
Published in Frontiers in immunology (2023)
Published in Frontiers in immunology (2023)
Get full text
Journal Article
Chaperone-Mediated Autophagy Upregulation Rescues Megalin Expression and Localization in Cystinotic Proximal Tubule Cells
Zhang, Jinzhong, He, Jing, Johnson, Jennifer L, Rahman, Farhana, Gavathiotis, Evripidis, Cuervo, Ana Maria, Catz, Sergio D
Published in Frontiers in endocrinology (Lausanne) (01.02.2019)
Published in Frontiers in endocrinology (Lausanne) (01.02.2019)
Get full text
Journal Article
Rab27a and Rab27b Regulate Neutrophil Azurophilic Granule Exocytosis and NADPH oxidase Activity by Independent Mechanisms
Johnson, Jennifer L, Brzezinska, Agnieszka A, Tolmachova, Tanya, Munafo, Daniela B, Ellis, Beverly A, Seabra, Miguel C, Hong, Hong, Catz, Sergio D
Published in Traffic (Copenhagen, Denmark) (01.04.2010)
Published in Traffic (Copenhagen, Denmark) (01.04.2010)
Get full text
Journal Article