The Receptor TGR5 Mediates the Prokinetic Actions of Intestinal Bile Acids and Is Required for Normal Defecation in Mice
Alemi, Farzad, Poole, Daniel P, Chiu, Jonathan, Schoonjans, Kristina, Cattaruzza, Fiore, Grider, John R, Bunnett, Nigel W, Corvera, Carlos U
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2013)
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Journal Article
The TGR5 receptor mediates bile acid-induced itch and analgesia
Alemi, Farzad, Kwon, Edwin, Poole, Daniel P, Lieu, TinaMarie, Lyo, Victoria, Cattaruzza, Fiore, Cevikbas, Ferda, Steinhoff, Martin, Nassini, Romina, Materazzi, Serena, Guerrero-Alba, Raquel, Valdez-Morales, Eduardo, Cottrell, Graeme S, Schoonjans, Kristina, Geppetti, Pierangelo, Vanner, Stephen J, Bunnett, Nigel W, Corvera, Carlos U
Published in The Journal of clinical investigation (01.04.2013)
Published in The Journal of clinical investigation (01.04.2013)
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Journal Article
Transient receptor potential ankyrin-1 has a major role in mediating visceral pain in mice
Cattaruzza, Fiore, Spreadbury, Ian, Miranda-Morales, Marcela, Grady, Eileen F, Vanner, Stephen, Bunnett, Nigel W
Published in American journal of physiology: Gastrointestinal and liver physiology (01.01.2010)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.01.2010)
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Journal Article
RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common Wnt pathway mutations
Fischer, Marcus M, Yeung, V Pete, Cattaruzza, Fiore, Hussein, Rajaa, Yen, Wan-Ching, Murriel, Christopher, Evans, James W, O'Young, Gilbert, Brunner, Alayne L, Wang, Min, Cain, Jennifer, Cancilla, Belinda, Kapoun, Ann, Hoey, Timothy
Published in Scientific reports (10.11.2017)
Published in Scientific reports (10.11.2017)
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Journal Article
Non-invasive imaging and cellular tracking of pulmonary emboli by near-infrared fluorescence and positron-emission tomography
Page, Michael J, Lourenço, André L, David, Tovo, LeBeau, Aaron M, Cattaruzza, Fiore, Castro, Helena C, VanBrocklin, Henry F, Coughlin, Shaun R, Craik, Charles S
Published in Nature communications (01.10.2015)
Published in Nature communications (01.10.2015)
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Journal Article
Transient Receptor Potential Ankyrin 1 Is Expressed by Inhibitory Motoneurons of the Mouse Intestine
Poole, Daniel P, Pelayo, Juan Carlos, Cattaruzza, Fiore, Kuo, Yien–Ming, Gai, Gregory, Chiu, Jonathon V, Bron, Romke, Furness, John B, Grady, Eileen F, Bunnett, Nigel W
Published in Gastroenterology (New York, N.Y. 1943) (01.08.2011)
Published in Gastroenterology (New York, N.Y. 1943) (01.08.2011)
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Journal Article
Transient receptor potential ion channels V4 and A1 contribute to pancreatitis pain in mice
Ceppa, Eugene, Cattaruzza, Fiore, Lyo, Victoria, Amadesi, Silvia, Pelayo, Juan-Carlos, Poole, Daniel P, Vaksman, Natalya, Liedtke, Wolfgang, Cohen, David M, Grady, Eileen F, Bunnett, Nigel W, Kirkwood, Kimberly S
Published in American journal of physiology: Gastrointestinal and liver physiology (01.09.2010)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.09.2010)
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Journal Article
Pungent General Anesthetics Activate Transient Receptor Potential-A1 to Produce Hyperalgesia and Neurogenic Bronchoconstriction
EILERS, Helge, CATTARUZZA, Fiore, NASSINI, Romina, MATERAZZI, Serena, ANDRE, Eunice, CHU, Catherine, COTTRELL, Graeme S, SCHUMACHER, Mark, GEPPETTI, Pierangelo, BUNNETT, Nigel W
Published in Anesthesiology (Philadelphia) (01.06.2010)
Published in Anesthesiology (Philadelphia) (01.06.2010)
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Journal Article
Serine proteases mediate inflammatory pain in acute pancreatitis
Ceppa, Eugene P, Lyo, Victoria, Grady, Eileen F, Knecht, Wolfgang, Grahn, Sarah, Peterson, Anders, Bunnett, Nigel W, Kirkwood, Kimberly S, Cattaruzza, Fiore
Published in American journal of physiology: Gastrointestinal and liver physiology (01.06.2011)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.06.2011)
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Journal Article
613 HER2-XPAT, a novel protease-activatable prodrug T cell engager (TCE), with potent T-cell activation and efficacy in solid tumors and large predicted safety margins in non-human primate (NHP)
Cattaruzza, Fiore, Nazeer, Ayesha, Lange, Zachary, Koski, Caitlin, Hammond, Mikhail, Dao-Pick, Trang, Henkensiefken, Angela, Derynck, Mika, Schellenberger, Volker, Irving, Bryan
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
Spinal microglia are activated in a painful model of murine chronic pancreatitis
Johnson, Cali, BA, Cattaruzza, Fiore, PhD, Bondada, Sandhya, MD, Cevikbas, Ferda, PhD, Cedron, Wendy, MS, Grady, Eileen F., PhD, Kirkwood, Kimberly S., MD, FACS
Published in Journal of the American College of Surgeons (01.09.2012)
Published in Journal of the American College of Surgeons (01.09.2012)
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Journal Article
Cerulein-treated Ras-activated mice develop painful chronic pancreatitis
Bondada, Sandhya, MD, Johnson, Cali, BA, Cattaruzza, Fiore, PhD, Cedron, Wendy, BA, Grady, Eileen, PhD, Ji, Baoan, PhD, Logsdon, Craig, PhD, Kirkwood, Kimberly S., MD, FACS
Published in Journal of the American College of Surgeons (01.09.2012)
Published in Journal of the American College of Surgeons (01.09.2012)
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Journal Article
The neuropathic pain mediator Cathepsin S (CatS) promotes activation of nociceptive pathways in mouse pancreas
Lyo, Victoria, Walker, Austin, BS, Kim, Tyson, Cattaruzza, Fiore, PhD, Bogyo, Matthew, PhD, Grady, Eileen, PhD, Bunnett, Nigel W., PhD, Kirkwood, Kimberly S., MD, FACS
Published in Journal of the American College of Surgeons (2011)
Published in Journal of the American College of Surgeons (2011)
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Journal Article
Localization and identification of protease activity in acute pancreatitis using in vivo molecular imaging
Lyo, Victoria, BA, Cattaruzza, Fiore, PhD, Paulick, Margot G., PhD, Pasricha, Pankaj J., MD, Bogyo, Matthew, PhD, Eileen, Grady F., PhD, Bunnett, Nigel W., PhD, Kirkwood, Kimberly S., MD, FACS
Published in Journal of the American College of Surgeons (2010)
Published in Journal of the American College of Surgeons (2010)
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Journal Article
Abstract 3376: HER2-XPAT and EGFR-XPAT: Pro-drug T-cell engagers (TCEs) engineered to address o n -target, o ff -tumor toxicity with potent efficacy in vitro and in vivo and large safety margins in NHP
Cattaruzza, Fiore, Nazeer, Ayesha, Lange, Zachary, Hammond, Mikhail, Koski, Caitlin, Henkensiefken, Angela, Derynck, Mika K., Irving, Bryan, Schellenberger, Volker
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 1824: HER2-XPAT, a novel protease-activatable T-cell engager (TCE) with potent T-cell activation and efficacy in solid tumors and large safety margins in non-human primate (NHP)
Cattaruzza, Fiore, Nazeer, Ayesha, Lange, Zachary, Koski, Caitlin, Hammond, Mikhail, To, Milton, Yeung, Pete, Lam, Sharon, Derynck, Mika K., Irving, Bryan, Schellenberger, Volker
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract PS17-11: Her2-xpat, a novel protease-activatable prodrug t-cell engager (tce), exhibits potent t-cell activation and efficacy in her2 tumors, yielding large predicted safety margins based on non-human primate (nhp)
Cattaruzza, Fiore, Nazeer, Ayesha, Lange, Zachary, Koski, Caitlin, Hammond, Mikhail, Henkensiefken, Angela, Dao-Pick, Trang, Derynck, Mika K, Irving, Bryan, Schellenberger, Volker
Published in Cancer research (Chicago, Ill.) (15.02.2021)
Published in Cancer research (Chicago, Ill.) (15.02.2021)
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Journal Article
Abstract P193: AMX-818, a novel prodrug HER2-XPAT T-cell engager (TCE) with potent T cell activation, proteolytic cleavage and efficacy in xenograft tumors, and wide safety margins in NHP (Non Human Primate)
To, Milton, Yeung, Pete, Fox, Michael, Hammond, Mikhail, Cattaruzza, Fiore, Nazeer, Ayesha, Koski, Caitlin, Liu, Lucas, Khorsand, Sina, Rennerfeldt, Deena, Morrissey, Kari, Lange, Zachary, Dong, Ming, Lam, Sharon, Derynck, Mika K., Irving, Bryan A., Schellenberger, Volker
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
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Journal Article
Brain–Gut Interactions Increase Peripheral Nociceptive Signaling in Mice With Postinfectious Irritable Bowel Syndrome
Ibeakanma, Charles, Ochoa–Cortes, Fernando, Miranda–Morales, Marcela, McDonald, Todd, Spreadbury, Ian, Cenac, Nicolas, Cattaruzza, Fiore, Hurlbut, David, Vanner, Stephanie, Bunnett, Nigel, Vergnolle, Nathalie, Vanner, Stephen
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2011)
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2011)
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Journal Article
WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death
Fischer, Marcus M, Cancilla, Belinda, Yeung, V Pete, Cattaruzza, Fiore, Chartier, Cecile, Murriel, Christopher L, Cain, Jennifer, Tam, Raymond, Cheng, Chieh-Yang, Evans, James W, O'Young, Gilbert, Song, Xiaomei, Lewicki, John, Kapoun, Ann M, Gurney, Austin, Yen, Wan-Ching, Hoey, Timothy
Published in Science advances (01.06.2017)
Published in Science advances (01.06.2017)
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