The current drug discovery landscape for trypanosomiasis and leishmaniasis: Challenges and strategies to identify drug targets
Altamura, Fernando, Rajesh, Rishi, Catta‐Preta, Carolina M. C., Moretti, Nilmar S., Cestari, Igor
Published in Drug development research (01.04.2022)
Published in Drug development research (01.04.2022)
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Essential roles for deubiquitination in Leishmania life cycle progression
Damianou, Andreas, Burge, Rebecca J, Catta-Preta, Carolina M C, Geoghegan, Vincent, Nievas, Y Romina, Newling, Katherine, Brown, Elaine, Burchmore, Richard, Rodenko, Boris, Mottram, Jeremy C
Published in PLoS pathogens (01.06.2020)
Published in PLoS pathogens (01.06.2020)
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Journal Article
The ecotin-like peptidase inhibitor of Trypanosoma cruzi prevents TMPRSS2-PAR2-TLR4 crosstalk downmodulating infection and inflammation
Costa, Tatiana F R, Catta-Preta, Carolina M C, Goundry, Amy, Carvalho, Danielle B, Rodrigues, Nathalia S, Vivarini, Aislan C, de Abreu, Mayra Fonseca, Reis, Flavia C G, Lima, Ana Paula C A
Published in The FASEB journal (31.03.2024)
Published in The FASEB journal (31.03.2024)
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Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes
Eduful, Benjamin J, O’Byrne, Sean N, Temme, Louisa, Asquith, Christopher R. M, Liang, Yi, Picado, Alfredo, Pilotte, Joseph R, Hossain, Mohammad Anwar, Wells, Carrow I, Zuercher, William J, Catta-Preta, Carolina M. C, Zonzini Ramos, Priscila, Santiago, André de S, Couñago, Rafael M, Langendorf, Christopher G, Nay, Kévin, Oakhill, Jonathan S, Pulliam, Thomas L, Lin, Chenchu, Awad, Dominik, Willson, Timothy M, Frigo, Daniel E, Scott, John W, Drewry, David H
Published in Journal of medicinal chemistry (12.08.2021)
Published in Journal of medicinal chemistry (12.08.2021)
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Journal Article
Chromosomal assembly of the nuclear genome of the endosymbiont-bearing trypanosomatid Angomonas deanei
Davey, John W, Catta-Preta, Carolina M C, James, Sally, Forrester, Sarah, Motta, Maria Cristina M, Ashton, Peter D, Mottram, Jeremy C
Published in G3 : genes - genomes - genetics (01.01.2021)
Published in G3 : genes - genomes - genetics (01.01.2021)
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Journal Article
Effects of miltefosine on the proliferation, ultrastructure, and phospholipid composition of Angomonas deanei, a trypanosomatid protozoan that harbors a symbiotic bacterium
de Freitas-Junior, Paulo R.G., Catta-Preta, Carolina M.C., Andrade, Iamara da Silva, Cavalcanti, Danielle P., de Souza, Wanderley, Einicker-Lamas, Marcelo, Motta, Maria Cristina M.
Published in FEMS microbiology letters (01.08.2012)
Published in FEMS microbiology letters (01.08.2012)
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Journal Article
Endosymbiosis in trypanosomatid protozoa: the bacterium division is controlled during the host cell cycle
Catta-Preta, Carolina M C, Brum, Felipe L, da Silva, Camila C, Zuma, Aline A, Elias, Maria C, de Souza, Wanderley, Schenkman, Sergio, Motta, Maria Cristina M
Published in Frontiers in microbiology (02.06.2015)
Published in Frontiers in microbiology (02.06.2015)
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A Target Engagement Assay to Assess Uptake, Potency, and Retention of Antibiotics in Living Bacteria
Fanti, Rebeka C., Vasconcelos, Stanley N. S., Catta-Preta, Carolina M. C., Sullivan, Jaryd R., Riboldi, Gustavo P., dos Reis, Caio V., Ramos, Priscila Z., Edwards, Aled M., Behr, Marcel A., Couñago, Rafael M.
Published in ACS infectious diseases (12.08.2022)
Published in ACS infectious diseases (12.08.2022)
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A novel BRET-based assay to investigate binding and residence time of unmodified ligands to the human lysosomal ion channel TRPML1 in intact cells
Cunha, Micael R., Catta-Preta, Carolina M.C., Takarada, Jéssica E., Moreira, Gabriela A., Massirer, Katlin B., Couñago, Rafael M.
Published in The Journal of biological chemistry (01.06.2023)
Published in The Journal of biological chemistry (01.06.2023)
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