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Pharmacokinetics and pharmacodynamics of the cathepsin S inhibitor, LY3000328, in healthy subjects
Payne, Christopher D., Deeg, Mark A., Chan, Melanie, Tan, Lai Hock, LaBell, Elizabeth Smith, Shen, Tong, DeBrota, David J.
Published in British journal of clinical pharmacology (01.12.2014)
Published in British journal of clinical pharmacology (01.12.2014)
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Tear Cathepsin S as a Candidate Biomarker for Sjögren's Syndrome
Hamm‐Alvarez, Sarah F., Janga, Srikanth R., Edman, Maria C., Madrigal, Sara, Shah, Mihir, Frousiakis, Starleen E., Renduchintala, Kavita, Zhu, Jay, Bricel, Seth, Silka, Kimberly, Bach, Dianne, Heur, Martin, Christianakis, Stratos, Arkfeld, Daniel G., Irvine, John, Mack, Wendy J., Stohl, William
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2014)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2014)
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Pathological α-syn aggregation is mediated by glycosphingolipid chain length and the physiological state of α-syn in vivo
Fredriksen, Kristina, Aivazidis, Stefanos, Sharma, Karan, Burbidge, Kevin J., Pitcairn, Caleb, Zunke, Friederike, Gelyana, Eilrayna, Mazzulli, Joseph R.
Published in Proceedings of the National Academy of Sciences - PNAS (14.12.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (14.12.2021)
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Protein Phosphatase 2A Reduces Cigarette Smoke–induced Cathepsin S and Loss of Lung Function
Doherty, Declan F., Nath, Sridesh, Poon, Justin, Foronjy, Robert F., Ohlmeyer, Michael, Dabo, Abdoulaye J., Salathe, Matthias, Birrell, Mark, Belvisi, Maria, Baumlin, Nathalie, Kim, Michael D., Weldon, Sinéad, Taggart, Clifford, Geraghty, Patrick
Published in American journal of respiratory and critical care medicine (01.07.2019)
Published in American journal of respiratory and critical care medicine (01.07.2019)
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Cellular depletion of major cathepsin proteases reveals their concerted activities for lysosomal proteolysis
Gallwitz, Lisa, Bleibaum, Florian, Voss, Matthias, Schweizer, Michaela, Spengler, Katharina, Winter, Dominic, Zöphel, Frederic, Müller, Stephan, Lichtenthaler, Stefan, Damme, Markus, Saftig, Paul
Published in Cellular and molecular life sciences : CMLS (01.12.2024)
Published in Cellular and molecular life sciences : CMLS (01.12.2024)
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Increased Cathepsin S activity associated with decreased protease inhibitory capacity contributes to altered tear proteins in Sjögren’s Syndrome patients
Edman, Maria C., Janga, Srikanth R., Meng, Zhen, Bechtold, Mercy, Chen, Alexander F., Kim, Chongiin, Naman, Luke, Sarma, Arunava, Teekappanavar, Neha, Kim, Alice Y., Madrigal, Sara, Singh, Simranjit, Ortiz, Elizabeth, Christianakis, Stratos, Arkfeld, Daniel G., Mack, Wendy J., Heur, Martin, Stohl, William, Hamm-Alvarez, Sarah F.
Published in Scientific reports (23.07.2018)
Published in Scientific reports (23.07.2018)
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Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo
Quillard, T, Croce, K, Jaffer, F A, Weissleder, R, Libby, P
Published in Thrombosis and haemostasis (01.05.2011)
Published in Thrombosis and haemostasis (01.05.2011)
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Pathogenesis of COPD. Part I. The role of protease-antiprotease imbalance in emphysema [State of the Art Series. Chronic obstructive pulmonary disease in high- and low-income countries. Edited by G. Marks and M. Chan-Yeung. Number 3 in the series]
ABBOUD, R. T, VIMALANATHAN, S
Published in The international journal of tuberculosis and lung disease (01.04.2008)
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Published in The international journal of tuberculosis and lung disease (01.04.2008)
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Cathepsins and cystatin C in atherosclerosis and obesity
Lafarge, Jean-Charles, Naour, Nadia, Clément, Karine, Guerre-Millo, Michèle
Published in Biochimie (01.11.2010)
Published in Biochimie (01.11.2010)
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Enzyme-specific differences in mannose phosphorylation between GlcNAc-1-phosphotransferase αβ and γ subunit deficient zebrafish support cathepsin proteases as early mediators of mucolipidosis pathology
Flanagan-Steet, Heather, Matheny, Courtney, Petrey, Aaron, Parker, Joshua, Steet, Richard
Published in Biochimica et biophysica acta (01.09.2016)
Published in Biochimica et biophysica acta (01.09.2016)
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Development of nitrile-based peptidic inhibitors of cysteine cathepsins
Frizler, Maxim, Stirnberg, Marit, Sisay, Mihiret Tekeste, Gütschow, Michael
Published in Current topics in medicinal chemistry (01.02.2010)
Published in Current topics in medicinal chemistry (01.02.2010)
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Cathepsins in Human Obesity: Changes in Energy Balance Predominantly Affect Cathepsin S in Adipose Tissue and in Circulation
Naour, Nadia, Rouault, Christine, Fellahi, Soraya, Lavoie, Marie-Eve, Poitou, Christine, Keophiphath, Mayoura, Eberlé, Delphine, Shoelson, Steve, Rizkalla, Salwa, Bastard, Jean-Philippe, Rabasa-Lhoret, Rémi, Clément, Karine, Guerre-Millo, Michèle
Published in The journal of clinical endocrinology and metabolism (01.04.2010)
Published in The journal of clinical endocrinology and metabolism (01.04.2010)
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Properties and applications of phytepsins from thistle flowers
Vairo Cavalli, Sandra, Lufrano, Daniela, Colombo, María Laura, Priolo, Nora
Published in Phytochemistry (Oxford) (01.08.2013)
Published in Phytochemistry (Oxford) (01.08.2013)
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Mast cells and neutrophils proteolytically activate chemokine precursor CTAP-III and are subject to counterregulation by PF-4 through inhibition of chymase and cathepsin G
Schiemann, Florian, Grimm, Tobias Alexander, Hoch, Josef, Gross, Roland, Lindner, Buko, Petersen, Frank, Bulfone-Paus, Silvia, Brandt, Ernst
Published in Blood (15.03.2006)
Published in Blood (15.03.2006)
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Decreased cathepsin V expression due to Fli1 deficiency contributes to the development of dermal fibrosis and proliferative vasculopathy in systemic sclerosis
Noda, S., Asano, Y., Takahashi, T., Akamata, K., Aozasa, N., Taniguchi, T., Ichimura, Y., Toyama, T., Sumida, H., Kuwano, Y., Yanaba, K., Tada, Y., Sugaya, M., Kadono, T., Sato, S.
Published in Rheumatology (Oxford, England) (01.05.2013)
Published in Rheumatology (Oxford, England) (01.05.2013)
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Non-Invasive Imaging of Cysteine Cathepsin Activity in Solid Tumors Using a 64Cu-Labeled Activity-Based Probe
Ren, Gang, Blum, Galia, Verdoes, Martijn, Liu, Hongguang, Syed, Salahuddin, Edgington, Laura E., Gheysens, Olivier, Miao, Zheng, Jiang, Han, Gambhir, Sanjiv Sam, Bogyo, Matthew, Cheng, Zhen
Published in PloS one (21.11.2011)
Published in PloS one (21.11.2011)
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