Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis
Afonso, Marta B, Rodrigues, Pedro M, Carvalho, Tânia, Caridade, Marta, Borralho, Paula, Cortez-Pinto, Helena, Castro, Rui E, Rodrigues, Cecília M P
Published in Clinical science (1979) (01.10.2015)
Published in Clinical science (1979) (01.10.2015)
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Journal Article
miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease
Castro, Rui E, Ferreira, Duarte M.S, Afonso, Marta B, Borralho, Pedro M, Machado, Mariana V, Cortez-Pinto, Helena, Rodrigues, Cecília M.P
Published in Journal of hepatology (01.01.2013)
Published in Journal of hepatology (01.01.2013)
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Journal Article
RIPK3 acts as a lipid metabolism regulator contributing to inflammation and carcinogenesis in non-alcoholic fatty liver disease
Afonso, Marta B, Rodrigues, Pedro M, Mateus-Pinheiro, Miguel, Simão, André L, Gaspar, Maria M, Majdi, Amine, Arretxe, Enara, Alonso, Cristina, Santos-Laso, Alvaro, Jimenez-Agüero, Raul, Eizaguirre, Emma, Bujanda, Luis, Pareja, Maria Jesus, Banales, Jesus M, Ratziu, Vlad, Gautheron, Jeremie, Castro, Rui E, Rodrigues, Cecília M P
Published in Gut (01.12.2021)
Published in Gut (01.12.2021)
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Journal Article
miRNA-21 ablation protects against liver injury and necroptosis in cholestasis
Afonso, Marta B., Rodrigues, Pedro M., Simão, André L., Gaspar, Maria M., Carvalho, Tânia, Borralho, Paula, Bañales, Jesús M., Castro, Rui E., Rodrigues, Cecília M. P.
Published in Cell death and differentiation (01.05.2018)
Published in Cell death and differentiation (01.05.2018)
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Journal Article
Diagnostic and prognostic biomarkers in cholangiocarcinoma
Macias, Rocio I. R., Kornek, Miroslaw, Rodrigues, Pedro M., Paiva, Nuno A., Castro, Rui E., Urban, Sabine, Pereira, Stephen P., Cadamuro, Massimiliano, Rupp, Christian, Loosen, Sven H., Luedde, Tom, Banales, Jesus M.
Published in Liver international (01.05.2019)
Published in Liver international (01.05.2019)
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Journal Article
Processes exacerbating apoptosis in non-alcoholic steatohepatitis
Afonso, Marta B, Castro, Rui E, Rodrigues, Cecília M P
Published in Clinical science (1979) (29.11.2019)
Published in Clinical science (1979) (29.11.2019)
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Journal Article
miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice
Rodrigues, Pedro M, Afonso, Marta B, Simão, André L, Carvalho, Catarina C, Trindade, Alexandre, Duarte, António, Borralho, Pedro M, Machado, Mariana V, Cortez-Pinto, Helena, Rodrigues, Cecília MP, Castro, Rui E
Published in Cell death & disease (13.04.2017)
Published in Cell death & disease (13.04.2017)
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Journal Article
MicroRNA‐143 reduces viability and increases sensitivity to 5‐fluorouracil in HCT116 human colorectal cancer cells
Borralho, Pedro M., Kren, Betsy T., Castro, Rui E., Moreira da Silva, Isabel B., Steer, Clifford J., Rodrigues, Cecília M. P.
Published in The FEBS journal (01.11.2009)
Published in The FEBS journal (01.11.2009)
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Journal Article
Impact of aging on primary liver cancer: epidemiology, pathogenesis and therapeutics
Macias, Rocio I R, Monte, Maria J, Serrano, Maria A, González-Santiago, Jesús M, Martín-Arribas, Isabel, Simão, André L, Castro, Rui E, González-Gallego, Javier, Mauriz, José L, Marin, Jose J G
Published in Aging (Albany, NY.) (11.10.2021)
Published in Aging (Albany, NY.) (11.10.2021)
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Journal Article
c-Jun N-Terminal Kinase 1/c-Jun Activation of the p53/MicroRNA 34a/Sirtuin 1 Pathway Contributes to Apoptosis Induced by Deoxycholic Acid in Rat Liver
Ferreira, Duarte M. S., Afonso, Marta B., Rodrigues, Pedro M., Simão, André L., Pereira, Diane M., Borralho, Pedro M., Rodrigues, Cecília M. P., Castro, Rui E.
Published in Molecular and Cellular Biology (01.03.2014)
Published in Molecular and Cellular Biology (01.03.2014)
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Journal Article
Deoxycholic acid modulates cell death signaling through changes in mitochondrial membrane properties[S]
Sousa, Tânia, Castro, Rui E., Pinto, Sandra N., Coutinho, Ana, Lucas, Susana D., Moreira, Rui, Rodrigues, Cecília M.P., Prieto, Manuel, Fernandes, Fábio
Published in Journal of lipid research (01.11.2015)
Published in Journal of lipid research (01.11.2015)
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Journal Article
MEK5/ERK5 signaling inhibition increases colon cancer cell sensitivity to 5-fluorouracil through a p53-dependent mechanism
Pereira, Diane M, Simões, André E S, Gomes, Sofia E, Castro, Rui E, Carvalho, Tânia, Rodrigues, Cecília M P, Borralho, Pedro M
Published in Oncotarget (07.06.2016)
Published in Oncotarget (07.06.2016)
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Journal Article
Liquid Biopsies in Hepatocellular Carcinoma: Are We Winning?
Mocan, Tudor, Simão, André L, Castro, Rui E, Rodrigues, Cecília M P, Słomka, Artur, Wang, Bingduo, Strassburg, Christian, Wöhler, Aliona, Willms, Arnulf G, Kornek, Miroslaw
Published in Journal of clinical medicine (20.05.2020)
Published in Journal of clinical medicine (20.05.2020)
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Journal Article
miR-143 overexpression impairs growth of human colon carcinoma xenografts in mice with induction of apoptosis and inhibition of proliferation
Borralho, Pedro M, Simões, André E S, Gomes, Sofia E, Lima, Raquel T, Carvalho, Tânia, Ferreira, Duarte M S, Vasconcelos, Maria H, Castro, Rui E, Rodrigues, Cecília M P
Published in PloS one (25.08.2011)
Published in PloS one (25.08.2011)
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Journal Article
Adiponectin, Leptin, and IGF-1 Are Useful Diagnostic and Stratification Biomarkers of NAFLD
Marques, Vanda, Afonso, Marta B., Bierig, Nina, Duarte-Ramos, Filipa, Santos-Laso, Álvaro, Jimenez-Agüero, Raul, Eizaguirre, Emma, Bujanda, Luis, Pareja, Maria J., Luís, Rita, Costa, Adília, Machado, Mariana V., Alonso, Cristina, Arretxe, Enara, Alustiza, José M., Krawczyk, Marcin, Lammert, Frank, Tiniakos, Dina G., Flehmig, Bertram, Cortez-Pinto, Helena, Banales, Jesus M., Castro, Rui E., Normann, Andrea, Rodrigues, Cecília M. P.
Published in Frontiers in medicine (23.06.2021)
Published in Frontiers in medicine (23.06.2021)
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Journal Article
Potential of miR-21 to Predict Incomplete Response to Chemoradiotherapy in Rectal Adenocarcinoma
Ourô, Susana, Mourato, Cláudia, Velho, Sónia, Cardador, André, Ferreira, Marisa P., Albergaria, Diogo, Castro, Rui E., Maio, Rui, Rodrigues, Cecília M. P.
Published in Frontiers in oncology (27.10.2020)
Published in Frontiers in oncology (27.10.2020)
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Journal Article
miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease
Fernández-Tussy, Pablo, Fernández-Ramos, David, Lopitz-Otsoa, Fernando, Simón, Jorge, Barbier-Torres, Lucía, Gomez-Santos, Beatriz, Nuñez-Garcia, Maitane, Azkargorta, Mikel, Gutiérrez-de Juan, Virginia, Serrano-Macia, Marina, Rodríguez-Agudo, Rubén, Iruzubieta, Paula, Anguita, Juan, Castro, Rui E., Champagne, Devin, Rincón, Mercedes, Elortza, Felix, Arslanow, Anita, Krawczyk, Marcin, Lammert, Frank, Kirchmeyer, Mélanie, Behrmann, Iris, Crespo, Javier, Lu, Shelly C., Mato, José M., Varela-Rey, Marta, Aspichueta, Patricia, Delgado, Teresa C., Martínez-Chantar, María L.
Published in Molecular metabolism (Germany) (01.11.2019)
Published in Molecular metabolism (Germany) (01.11.2019)
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Journal Article
Identification of microRNAs during rat liver regeneration after partial hepatectomy and modulation by ursodeoxycholic acid
Castro, Rui E, Ferreira, Duarte M S, Zhang, Xiaoxiao, Borralho, Pedro M, Sarver, Aaron L, Zeng, Yan, Steer, Clifford J, Kren, Betsy T, Rodrigues, Cecília M P
Published in American journal of physiology: Gastrointestinal and liver physiology (01.10.2010)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.10.2010)
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Journal Article
The Emerging Role of microRNAs in Aquaporin Regulation
Gomes, André, da Silva, Inês V, Rodrigues, Cecília M P, Castro, Rui E, Soveral, Graça
Published in Frontiers in chemistry (21.06.2018)
Published in Frontiers in chemistry (21.06.2018)
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Journal Article
Cirrhosis is associated with lower serological responses to COVID-19 vaccines in patients with chronic liver disease
Simão, André Lopes, Palma, Carolina Santos, Izquierdo-Sanchez, Laura, Putignano, Antonella, Carvalho-Gomes, Angela, Posch, Andreas, Zanaga, Paola, Girleanu, Irina, Henrique, Mariana Moura, Araújo, Carlos, Degre, Delphine, Gustot, Thierry, Sahuco, Iván, Spagnolo, Elia, Carvalhana, Sofia, Moura, Miguel, Fernandes, Diogo AE, Banales, Jesus M., Romero-Gomez, Manuel, Trifan, Anca, Russo, Francesco Paolo, Stauber, Rudolf, Berenguer, Marina, Moreno, Christophe, Gonçalves, João, Cortez-Pinto, Helena, Castro, Rui E.
Published in JHEP reports (01.05.2023)
Published in JHEP reports (01.05.2023)
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