Molecular Lego of Human Cytochrome P450: The Key Role of Heme Domain Flexibility for the Activity of the Chimeric Proteins
Catucci, Gianluca, Ciaramella, Alberto, Di Nardo, Giovanna, Zhang, Chao, Castrignanò, Silvia, Gilardi, Gianfranco
Published in International journal of molecular sciences (25.03.2022)
Published in International journal of molecular sciences (25.03.2022)
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Journal Article
Human Flavin-Containing Monooxygenase 3 on Graphene Oxide for Drug Metabolism Screening
Castrignanò, Silvia, Gilardi, Gianfranco, Sadeghi, Sheila J
Published in Analytical chemistry (Washington) (03.03.2015)
Published in Analytical chemistry (Washington) (03.03.2015)
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Journal Article
Inactivation mechanism of N61S mutant of human FMO3 towards trimethylamine
Gao, Chongliang, Catucci, Gianluca, Castrignanò, Silvia, Gilardi, Gianfranco, Sadeghi, Sheila J
Published in Scientific reports (07.11.2017)
Published in Scientific reports (07.11.2017)
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Journal Article
Engineered human CYP2C9 and its main polymorphic variants for bioelectrochemical measurements of catalytic response
Panicco, Paola, Castrignanò, Silvia, Sadeghi, Sheila J., Nardo, Giovanna Di, Gilardi, Gianfranco
Published in Bioelectrochemistry (Amsterdam, Netherlands) (01.04.2021)
Published in Bioelectrochemistry (Amsterdam, Netherlands) (01.04.2021)
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Journal Article
Influence of inter-domain dynamics and surrounding environment flexibility on the direct electrochemistry and electrocatalysis of self-sufficient cytochrome P450 3A4-BMR chimeras
Castrignanò, Silvia, Di Nardo, Giovanna, Sadeghi, Sheila J., Gilardi, Gianfranco
Published in Journal of inorganic biochemistry (01.11.2018)
Published in Journal of inorganic biochemistry (01.11.2018)
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Journal Article
Modulation of the interaction between human P450 3A4 and B. megaterium reductase via engineered loops
Castrignanò, Silvia, D'Avino, Serena, Di Nardo, Giovanna, Catucci, Gianluca, Sadeghi, Sheila J., Gilardi, Gianfranco
Published in Biochimica et biophysica acta. Proteins and proteomics (01.01.2018)
Published in Biochimica et biophysica acta. Proteins and proteomics (01.01.2018)
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Journal Article
Hydrogen production at high Faradaic efficiency by a bio-electrode based on TiO2 adsorption of a new [FeFe]-hydrogenase from Clostridium perfringens
Morra, Simone, Valetti, Francesca, Sarasso, Veronica, Castrignanò, Silvia, Sadeghi, Sheila J., Gilardi, Gianfranco
Published in Bioelectrochemistry (Amsterdam, Netherlands) (01.12.2015)
Published in Bioelectrochemistry (Amsterdam, Netherlands) (01.12.2015)
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Journal Article
CYP116B5: a new class VII catalytically self‐sufficient cytochrome P450 from Acinetobacter radioresistens that enables growth on alkanes
Minerdi, Daniela, Sadeghi, Sheila J., Di Nardo, Giovanna, Rua, Francesco, Castrignanò, Silvia, Allegra, Paola, Gilardi, Gianfranco
Published in Molecular microbiology (01.02.2015)
Published in Molecular microbiology (01.02.2015)
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Journal Article
Bioelectrochemical profiling of two common polymorphic variants of human FMO3 in presence of graphene oxide
Castrignanò, Silvia, Bortolussi, Stefania, Catucci, Gianluca, Gholami, Omkolsum, Valetti, Francesca, Gilardi, Gianfranco, Sadeghi, Sheila J.
Published in Electrochimica acta (20.02.2017)
Published in Electrochimica acta (20.02.2017)
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Journal Article
Escherichia coli Overexpressing a Baeyer-Villiger Monooxygenase from Acinetobacter radioresistens Becomes Resistant to Imipenem
Minerdi, Daniela, Zgrablic, Ivan, Castrignanò, Silvia, Catucci, Gianluca, Medana, Claudio, Terlizzi, Maria Elena, Gribaudo, Giorgio, Gilardi, Gianfranco, Sadeghi, Sheila J
Published in Antimicrobial agents and chemotherapy (01.01.2016)
Published in Antimicrobial agents and chemotherapy (01.01.2016)
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Journal Article
Electrochemical Detection of Human Cytochrome P450 2A6 Inhibition: A Step toward Reducing Dependence on Smoking
Castrignanò, Silvia, Ortolani, Alex, Sadeghi, Sheila J., Di Nardo, Giovanna, Allegra, Paola, Gilardi, Gianfranco
Published in Analytical chemistry (Washington) (04.03.2014)
Published in Analytical chemistry (Washington) (04.03.2014)
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Journal Article
Polymorphism on human aromatase affects protein dynamics and substrate binding: spectroscopic evidence
Di Nardo, Giovanna, Di Venere, Almerinda, Zhang, Chao, Nicolai, Eleonora, Castrignanò, Silvia, Di Paola, Luisa, Gilardi, Gianfranco, Mei, Giampiero
Published in Biology direct (26.04.2021)
Published in Biology direct (26.04.2021)
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Journal Article
Dynamics and flexibility of human aromatase probed by FTIR and time resolved fluorescence spectroscopy
Di Nardo, Giovanna, Breitner, Maximilian, Sadeghi, Sheila J, Castrignanò, Silvia, Mei, Giampiero, Di Venere, Almerinda, Nicolai, Eleonora, Allegra, Paola, Gilardi, Gianfranco
Published in PloS one (11.12.2013)
Published in PloS one (11.12.2013)
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Journal Article
Human Cytochrome P450 3A4 as a Biocatalyst: Effects of the Engineered Linker in Modulation of Coupling Efficiency in 3A4-BMR Chimeras
Degregorio, Danilo, D'Avino, Serena, Castrignanò, Silvia, Di Nardo, Giovanna, Sadeghi, Sheila J, Catucci, Gianluca, Gilardi, Gianfranco
Published in Frontiers in pharmacology (21.03.2017)
Published in Frontiers in pharmacology (21.03.2017)
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Journal Article
Electrochemistry of Canis familiaris cytochrome P450 2D15 with gold nanoparticles: An alternative to animal testing in drug discovery
Rua, Francesco, Sadeghi, Sheila J., Castrignanò, Silvia, Valetti, Francesca, Gilardi, Gianfranco
Published in Bioelectrochemistry (Amsterdam, Netherlands) (01.10.2015)
Published in Bioelectrochemistry (Amsterdam, Netherlands) (01.10.2015)
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