PCR amplicons identify widespread copy number variation in human centromeric arrays and instability in cancer
de Lima, Leonardo Gomes, Howe, Edmund, Singh, Vijay Pratap, Potapova, Tamara, Li, Hua, Xu, Baoshan, Castle, Jemma, Crozier, Steve, Harrison, Christine J., Clifford, Steve C., Miga, Karen H., Ryan, Sarra L., Gerton, Jennifer L.
Published in Cell genomics (01.12.2021)
Published in Cell genomics (01.12.2021)
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Journal Article
Mild uncoupling of mitochondria synergistically enhances senolytic specificity and sensitivity of BH3 mimetics
Miwa, Satomi, Fielder, Edward, Ishaq, Abbas, Low, Evon, Calista, Aisha, Castle, Jemma, von Zglinicki, Thomas
Published in Biochimica et biophysica acta. Bioenergetics (01.09.2024)
Published in Biochimica et biophysica acta. Bioenergetics (01.09.2024)
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Journal Article
QOL-04.IN VIVO MODELLING RECAPITULATES RADIOTHERAPY DELIVERY AND LATE-EFFECT PROFILE FOR CHILDHOOD MEDULLOBLASTOMA
Castle, Jemma, Shaw, Gary, Weller, Dominic, Fielder, Edward, Egnuni, Teklu, Singh, Mankaran, Skinner, Roderick, von Zglinicki, Thomas, Clifford, Steven C, Short, Susan, Miwa, Satomi, Hicks, Debbie
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
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Journal Article
Medulloblastoma group 3 and 4 tumors comprise a clinically and biologically significant expression continuum reflecting human cerebellar development
Williamson, Daniel, Schwalbe, Edward C., Hicks, Debbie, Aldinger, Kimberly A., Lindsey, Janet C., Crosier, Stephen, Richardson, Stacey, Goddard, Jack, Hill, Rebecca M., Castle, Jemma, Grabovska, Yura, Hacking, James, Pizer, Barry, Wharton, Stephen B., Jacques, Thomas S., Joshi, Abhijit, Bailey, Simon, Clifford, Steven C.
Published in Cell reports (Cambridge) (02.08.2022)
Published in Cell reports (Cambridge) (02.08.2022)
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MDB-75. MOLECULAR PATHOLOGY, TREATMENT AND PROGNOSIS OF INFANT SONIC HEDGEHOG MEDULLOBLASTOMA: A GLOBAL MULTI-COHORT STUDY
Richardson, Stacey, Hicks, Debbie, Gough, Melissa, Castle, Jemma, Crosier, Stephen, Garcia-Ariza, Miguel, Martín-Guerrero, Idoia, LA Plasschaert, Sabine, Bourdeaut, Franck, Dufour, Christelle, Masliah-Planchon, Julien, Buttarelli, Francesca R, Garre, Maria-Luisa, Biassoni, Veronica, Massimino, Maura, Kanemura, Yonehiro, Ramaswamy, Vijay, Gajjar, Amar, Northcott, Paul, Robinson, Giles, Korshunov, Andrey, Pfister, Stefan M, Mynarek, Martin, Rutkowski, Stefan, Schwalbe, Edward C, Bailey, Simon, Clifford, Steven C
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
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QOL-28. Clinico-molecular correlates of quality of survival and neurocognitive outcomes in medulloblastoma; a meta-analysis of the SIOP-UKCCSG-PNET3 and HIT-SIOP-PNET4 trials
Chevignard, Mathilde, Bull, Kim S, Holt, James, Harrington, Bertie, Castle, Jemma, Heng, Marie-Amelie, Kennedy, Colin, Doz, Francois, Lannering, Birgitta, Rutkowski, Stefan, Massimino, Maura, Bailey, Simon, Oyefiade, Adeoye, Mabbott, Donald, Clifford†, Steven C, Hicks†, Debbie
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
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Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification
Goddard, Jack, Castle, Jemma, Southworth, Emily, Fletcher, Anya, Crosier, Stephen, Martin-Guerrero, Idoia, García-Ariza, Miguel, Navajas, Aurora, Masliah-Planchon, Julien, Bourdeaut, Franck, Dufour, Christelle, Ayrault, Olivier, Goschzik, Tobias, Pietsch, Torsten, Sill, Martin, Pfister, Stefan M., Rutkowski, Stefan, Richardson, Stacey, Hill, Rebecca M., Williamson, Daniel, Bailey, Simon, Schwalbe, Edward C., Clifford, Steven C., Hicks, Debbie
Published in Acta neuropathologica (01.05.2023)
Published in Acta neuropathologica (01.05.2023)
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EMBR-25. GENOME-WIDE GENETIC AND EPIGENETIC ASSESSMENT OF GROUP 4 MEDULLOBLASTOMA FOR IMPROVED, BIOMARKER DRIVEN, PROGNOSTICATION AND RISK-STRATIFICATION
Goddard, Jack, Castle, Jemma, Southworth, Emily, Crosier, Stephen, Martin-Guerrero, Idoia, Garcia-Ariza, Miguel, Navajas, Aurora, Bourdeaut, Franck, Dufour, Christelle, Goschzik, Tobias, Pietsch, Torsten, Williamson, Dan, Bailey, Simon, Schwalbe, Ed, Clifford, Steven, Hicks, Debbie
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2021)
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2021)
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MEDB-71. Molecular characterisation of group 4 medulloblastoma improves risk-stratification and its biological understanding
Goddard, Jack, Castle, Jemma, Southworth, Emily, Fletcher, Anya, Crosier, Stephen, Martin-Guerrero, Idoia, Garcia-Ariza, Miguel, Navajas, Aurora, Masliah-Planchon, Julien, Bourdeaut, Franck, Dufour, Christelle, Goschizk, Tobias, Pietsch, Torsten, Richardson, Stacey, Hill, Rebecca M, Williamson, Daniel, Bailey, Simon, Schwalbe, Edward C, Clifford, Steven C, Hicks, Debbie
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
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In vivo modeling recapitulates radiotherapy delivery and late-effect profile for childhood medulloblastoma
Castle, Jemma, Shaw, Gary, Weller, Dominic, Fielder, Edward, Egnuni, Teklu, Singh, Mankaran, Skinner, Roderick, von Zglinicki, Thomas, Clifford, Steven C, Short, Susan C, Miwa, Satomi, Hicks, Debbie
Published in Neuro-oncology advances (01.01.2024)
Published in Neuro-oncology advances (01.01.2024)
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Journal Article
Medulloblastoma Group 3 and 4 Tumors Comprise a Clinically and Biologically Significant Expression Continuum Reflecting Human Cerebellar Development
Williamson, Daniel, Schwalbe, Edward C, Hicks, Debbie, Aldinger, Kimberly A, Lindsey, Janet, Crosier, Stephen, Richardson, Stacey, Goddard, Jack, Hill, Rebecca, Castle, Jemma, Grabovska, Yura, Hacking, James, Pizer, Barry, Wharton, Stephen B, Jacques, Thomas S, Joshi, Abhijit, Bailey, Simon, Clifford, Steven C
Published in bioRxiv (12.06.2022)
Published in bioRxiv (12.06.2022)
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