Deubiquitinating enzymes USP4 and USP17 finetune the trafficking of PDGFRβ and affect PDGF-BB-induced STAT3 signalling
Sarri, Niki, Wang, Kehuan, Tsioumpekou, Maria, Castillejo-López, Casimiro, Lennartsson, Johan, Heldin, Carl-Henrik, Papadopoulos, Natalia
Published in Cellular and molecular life sciences : CMLS (01.02.2022)
Published in Cellular and molecular life sciences : CMLS (01.02.2022)
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Journal Article
Proof-of-concept for CRISPR/Cas9 gene editing in human preadipocytes: Deletion of FKBP5 and PPARG and effects on adipocyte differentiation and metabolism
Kamble, Prasad G., Hetty, Susanne, Vranic, Milica, Almby, Kristina, Castillejo-López, Casimiro, Abalo, Xesús M., Pereira, Maria J., Eriksson, Jan W.
Published in Scientific reports (29.06.2020)
Published in Scientific reports (29.06.2020)
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Journal Article
A regulatory element associated to NAFLD in the promoter of DIO1 controls LDL-C, HDL-C and triglycerides in hepatic cells
Castillejo-López, Casimiro, Bárcenas-Walls, José Ramón, Cavalli, Marco, Larsson, Anders, Wadelius, Claes
Published in Lipids in health and disease (16.02.2024)
Published in Lipids in health and disease (16.02.2024)
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Journal Article
BANK1 and BLK act through phospholipase C gamma 2 in B-cell signaling
Bernal-Quirós, Manuel, Wu, Ying-Yu, Alarcón-Riquelme, Marta E, Castillejo-López, Casimiro
Published in PloS one (26.03.2013)
Published in PloS one (26.03.2013)
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Journal Article
CRISPR-Cas9-mediated knockout of SPRY2 in human hepatocytes leads to increased glucose uptake and lipid droplet accumulation
Cook, Naomi L, Pjanic, Milos, Emmerich, Andrew G, Rao, Abhiram S, Hetty, Susanne, Knowles, Joshua W, Quertermous, Thomas, Castillejo-López, Casimiro, Ingelsson, Erik
Published in BMC endocrine disorders (29.10.2019)
Published in BMC endocrine disorders (29.10.2019)
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Journal Article
SIDT1 plays a key role in type I IFN responses to nucleic acids in plasmacytoid dendritic cells and mediates the pathogenesis of an imiquimod-induced psoriasis model
Morell, María, Varela, Nieves, Castillejo-López, Casimiro, Coppard, Céline, Luque, María José, Wu, Ying-Yu, Martín-Morales, Natividad, Pérez-Cózar, Francisco, Gómez-Hernández, Gonzalo, Kumar, Ramesh, O'Valle, Francisco, Alarcón-Riquelme, Marta E., Marañón, Concepción
Published in EBioMedicine (01.02.2022)
Published in EBioMedicine (01.02.2022)
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Journal Article
Monoallelic and bi-allelic variants in NCDN cause neurodevelopmental delay, intellectual disability, and epilepsy
Fatima, Ambrin, Hoeber, Jan, Schuster, Jens, Koshimizu, Eriko, Maya-Gonzalez, Carolina, Keren, Boris, Mignot, Cyril, Akram, Talia, Ali, Zafar, Miyatake, Satoko, Tanigawa, Junpei, Koike, Takayoshi, Kato, Mitsuhiro, Murakami, Yoshiko, Abdullah, Uzma, Ali, Muhammad Akhtar, Fadoul, Rein, Laan, Loora, Castillejo-López, Casimiro, Liik, Maarika, Jin, Zhe, Birnir, Bryndis, Matsumoto, Naomichi, Baig, Shahid M., Klar, Joakim, Dahl, Niklas
Published in American journal of human genetics (01.04.2021)
Published in American journal of human genetics (01.04.2021)
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Journal Article
FKBP5 expression in human adipose tissue: potential role in glucose and lipid metabolism, adipogenesis and type 2 diabetes
Sidibeh, Cherno O., Pereira, Maria J., Abalo, Xesus M., J. Boersma, Gretha, Skrtic, Stanko, Lundkvist, Per, Katsogiannos, Petros, Hausch, Felix, Castillejo-López, Casimiro, Eriksson, Jan W.
Published in Endocrine (01.10.2018)
Published in Endocrine (01.10.2018)
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Journal Article
Monoallelic and bi-allelic variants in NCDN cause neurodevelopmental delay, intellectual disability, and epilepsy
Fatima, Ambrin, Hoeber, Jan, Schuster, Jens, Koshimizu, Eriko, Maya-Gonzalez, Carolina, Keren, Boris, Mignot, Cyril, Akram, Talia, Ali, Zafar, Miyatake, Satoko, Tanigawa, Junpei, Koike, Takayoshi, Kato, Mitsuhiro, Murakami, Yoshiko, Abdullah, Uzma, Ali, Muhammad Akhtar, Fadoul, Rein, Laan, Loora, Castillejo-López, Casimiro, Liik, Maarika, Jin, Zhe, Birnir, Bryndis, Matsumoto, Naomichi, Baig, Shahid M., Klar, Joakim, Dahl, Niklas
Published in American journal of human genetics (03.03.2022)
Published in American journal of human genetics (03.03.2022)
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Journal Article
Recent findings on genetics of systemic autoimmune diseases
Delgado-Vega, Angélica, Sánchez, Elena, Löfgren, Sara, Castillejo-López, Casimiro, Alarcón-Riquelme, Marta E
Published in Current opinion in immunology (01.12.2010)
Published in Current opinion in immunology (01.12.2010)
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Journal Article
A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans
Alcocer-Varela, Jorge, Castillejo-López, Casimiro, Sturfelt, Gunnar, Gunnarsson, Iva, Alarcón-Riquelme, Marta E, Bolstad, Anne Isine, Svenungsson, Elisabet, Lundberg, Ingrid, Prokunina, Ludmila, Kristjansdóttir, Helga, Gröndal, Gerdur, Harley, John B, Lima, Guadalupe, Berg, Louise, Truedsson, Lennart, Tentler, Dmitry, Jönssen, Andreas, Jonsson, Roland, Magnusson, Veronica, Steinsson, Kristján, Öberg, Fredrik, Brookes, Anthony J, Gyllensten, Ulf B, Alarcón-Segovia, Donato
Published in Nature Genetics (01.12.2002)
Published in Nature Genetics (01.12.2002)
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Book Review
Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues
Diamanti, Klev, Cavalli, Marco, Pereira, Maria J, Pan, Gang, Castillejo-López, Casimiro, Kumar, Chanchal, Mundt, Filip, Komorowski, Jan, Deshmukh, Atul S, Mann, Matthias, Korsgren, Olle, Eriksson, Jan W, Wadelius, Claes
Published in Cell reports. Medicine (18.10.2022)
Published in Cell reports. Medicine (18.10.2022)
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Journal Article
Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK
Castillejo-López, Casimiro, Delgado-Vega, Angélica M, Wojcik, Jerome, Kozyrev, Sergey V, Thavathiru, Elangovan, Wu, Ying-Yu, Sánchez, Elena, Pöllmann, David, López-Egido, Juan R, Fineschi, Serena, Domínguez, Nicolás, Lu, Rufei, James, Judith A, Merrill, Joan T, Kelly, Jennifer A, Kaufman, Kenneth M, Moser, Kathy L, Gilkeson, Gary, Frostegård, Johan, Pons-Estel, Bernardo A, D'Alfonso, Sandra, Witte, Torsten, Callejas, José Luis, Harley, John B, Gaffney, Patrick M, Martin, Javier, Guthridge, Joel M, Alarcón-Riquelme, Marta E
Published in Annals of the rheumatic diseases (01.01.2012)
Published in Annals of the rheumatic diseases (01.01.2012)
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Journal Article
Perlecan and Dystroglycan act at the basal side of the Drosophila follicular epithelium to maintain epithelial organization
Schneider, Martina, Khalil, Ashraf A, Poulton, John, Castillejo-Lopez, Casimiro, Egger-Adam, Diane, Wodarz, Andreas, Deng, Wu-Min, Baumgartner, Stefan
Published in Development (Cambridge) (01.10.2006)
Published in Development (Cambridge) (01.10.2006)
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Journal Article
Detailed Functional Characterization of a Waist-Hip Ratio Locus in 7p15.2 Defines an Enhancer Controlling Adipocyte Differentiation
Castillejo-Lopez, Casimiro, Pjanic, Milos, Pirona, Anna Chiara, Hetty, Susanne, Wabitsch, Martin, Wadelius, Claes, Quertermous, Thomas, Arner, Erik, Ingelsson, Erik
Published in iScience (25.10.2019)
Published in iScience (25.10.2019)
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Journal Article
Dystroglycan is required for polarizing the epithelial cells and the oocyte in Drosophila
Deng, W-M, Schneider, M, Frock, R, Castillejo-Lopez, C, Gaman, E A, Baumgartner, S, Ruohola-Baker, H
Published in Development (Cambridge) (01.01.2003)
Published in Development (Cambridge) (01.01.2003)
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