Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy
Nelson, Christopher E., Wu, Yaoying, Gemberling, Matthew P., Oliver, Matthew L., Waller, Matthew A., Bohning, Joel D., Robinson-Hamm, Jacqueline N., Bulaklak, Karen, Castellanos Rivera, Ruth M., Collier, Joel H., Asokan, Aravind, Gersbach, Charles A.
Published in Nature medicine (01.03.2019)
Published in Nature medicine (01.03.2019)
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In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy
Nelson, Christopher E., Hakim, Chady H., Ousterout, David G., Thakore, Pratiksha I., Moreb, Eirik A., Rivera, Ruth M. Castellanos, Madhavan, Sarina, Pan, Xiufang, Ran, F. Ann, Yan, Winston X., Asokan, Aravind, Zhang, Feng, Duan, Dongsheng, Gersbach, Charles A.
Published in Science (American Association for the Advancement of Science) (22.01.2016)
Published in Science (American Association for the Advancement of Science) (22.01.2016)
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Structure-guided evolution of antigenically distinct adeno-associated virus variants for immune evasion
Tse, Longping Victor, Klinc, Kelli A., Madigan, Victoria J., Rivera, Ruth M. Castellanos, Wells, Lindsey F., Havlik, L. Patrick, Smith, J. Kennon, Agbandje-McKenna, Mavis, Asokan, Aravind
Published in Proceedings of the National Academy of Sciences - PNAS (13.06.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (13.06.2017)
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Aquaporin-4-dependent glymphatic solute transport in the rodent brain
Mestre, Humberto, Hablitz, Lauren M, Xavier, Anna Lr, Feng, Weixi, Zou, Wenyan, Pu, Tinglin, Monai, Hiromu, Murlidharan, Giridhar, Castellanos Rivera, Ruth M, Simon, Matthew J, Pike, Martin M, Plá, Virginia, Du, Ting, Kress, Benjamin T, Wang, Xiaowen, Plog, Benjamin A, Thrane, Alexander S, Lundgaard, Iben, Abe, Yoichiro, Yasui, Masato, Thomas, John H, Xiao, Ming, Hirase, Hajime, Asokan, Aravind, Iliff, Jeffrey J, Nedergaard, Maiken
Published in eLife (18.12.2018)
Published in eLife (18.12.2018)
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Tissue-Dependent Expression and Translation of Circular RNAs with Recombinant AAV Vectors In Vivo
Meganck, Rita M., Borchardt, Erin K., Castellanos Rivera, Ruth M., Scalabrino, Miranda L., Wilusz, Jeremy E., Marzluff, William F., Asokan, Aravind
Published in Molecular therapy. Nucleic acids (07.12.2018)
Published in Molecular therapy. Nucleic acids (07.12.2018)
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Structure-guided AAV capsid evolution strategies for enhanced CNS gene delivery
Gonzalez, Trevor J., Mitchell-Dick, Aaron, Blondel, Leo O., Fanous, Marco M., Hull, Joshua A., Oh, Daniel K., Moller-Tank, Sven, Castellanos Rivera, Ruth M., Piedrahita, Jorge A., Asokan, Aravind
Published in Nature protocols (01.11.2023)
Published in Nature protocols (01.11.2023)
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Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing
Gonzalez, Trevor J., Simon, Katherine E., Blondel, Leo O., Fanous, Marco M., Roger, Angela L., Maysonet, Maribel Santiago, Devlin, Garth W., Smith, Timothy J., Oh, Daniel K., Havlik, L. Patrick, Castellanos Rivera, Ruth M., Piedrahita, Jorge A., ElMallah, Mai K., Gersbach, Charles A., Asokan, Aravind
Published in Nature communications (10.10.2022)
Published in Nature communications (10.10.2022)
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Integrating genetic and network analysis to characterize genes related to mouse weight
Ghazalpour, Anatole, Doss, Sudheer, Zhang, Bin, Wang, Susanna, Plaisier, Christopher, Castellanos, Ruth, Brozell, Alec, Schadt, Eric E, Drake, Thomas A, Lusis, Aldons J, Horvath, Steve
Published in PLoS genetics (01.08.2006)
Published in PLoS genetics (01.08.2006)
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Transcriptional regulator RBP-J regulates the number and plasticity of renin cells
Castellanos Rivera, Ruth M, Monteagudo, Maria C, Pentz, Ellen S, Glenn, Sean T, Gross, Kenneth W, Carretero, Oscar, Sequeira-Lopez, Maria Luisa S, Gomez, R Ariel
Published in Physiological genomics (01.09.2011)
Published in Physiological genomics (01.09.2011)
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Total mercury exposure risk and selenium content measuring on fishery products consumed by women of childbearing age from Bogota, Colombia
Mojica Cortes, Andrea del Pilar, Guerrero Montilla, Jaime Alberto, Sánchez Barrera, Iván Camilo, Vargas Hernández, Jhonny Eddison, Ruíz Pérez, Luz Adriana, Castro Aguilar, Diana Patricia, Noreña Trigos, Oscar Alberto, Castellanos García, Ruth, Pérez Castiblanco, Diana María
Published in Vitae (Medellín) (01.12.2021)
Published in Vitae (Medellín) (01.12.2021)
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Functional Analysis of the Putative Integrin Recognition Motif on Adeno-associated Virus 9
Shen, Shen, Berry, Garrett E., Castellanos Rivera, Ruth M., Cheung, Roland Y., Troupes, Andrew N., Brown, Sarah M., Kafri, Tal, Asokan, Aravind
Published in The Journal of biological chemistry (16.01.2015)
Published in The Journal of biological chemistry (16.01.2015)
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High-resolution mapping of gene expression using association in an outbred mouse stock
Ghazalpour, Anatole, Doss, Sudheer, Kang, Hyun, Farber, Charles, Wen, Ping-Zi, Brozell, Alec, Castellanos, Ruth, Eskin, Eleazar, Smith, Desmond J, Drake, Thomas A, Lusis, Aldons J
Published in PLoS genetics (01.08.2008)
Published in PLoS genetics (01.08.2008)
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Mapping the Structural Determinants Required for AAVrh.10 Transport across the Blood-Brain Barrier
Albright, Blake H., Storey, Claire M., Murlidharan, Giridhar, Castellanos Rivera, Ruth M., Berry, Garrett E., Madigan, Victoria J., Asokan, Aravind
Published in Molecular therapy (07.02.2018)
Published in Molecular therapy (07.02.2018)
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Recombination signal binding protein for Ig-κJ region regulates juxtaglomerular cell phenotype by activating the myo-endocrine program and suppressing ectopic gene expression
Castellanos-Rivera, Ruth M, Pentz, Ellen S, Lin, Eugene, Gross, Kenneth W, Medrano, Silvia, Yu, Jing, Sequeira-Lopez, Maria Luisa S, Gomez, R Ariel
Published in Journal of the American Society of Nephrology (01.01.2015)
Published in Journal of the American Society of Nephrology (01.01.2015)
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치료 항-IGF-1R 항체를 코딩하는 핵산의 전달을 위한 벡터 구축물 및 이를 사용하는 방법
SHEN WEIRAN, CASTELLANOS RUTH, STONE MICHELE, HEAH THERESA, GUPTA NACHIKETA, CEPEDA DIANA
Year of Publication 28.08.2024
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Year of Publication 28.08.2024
Patent
397. Correction of the Dystrophin Gene By the CRISPR/Cas9 System in a Mouse Model of Muscular Dystrophy
Nelson, Christopher E., Moreb, David G. Ousterout, Jacqueline N. Robinson-Hamm, Eirik A., Castellanos, Ruth M., Ann Ran, Fei, Yan, Winston, Zhang, Feng, Asokan, Aravind, Gersbach, Charles A.
Published in Molecular therapy (01.05.2015)
Published in Molecular therapy (01.05.2015)
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482. Local and Systemic Gene Editing in a Mouse Model of Duchenne Muscular Dystrophy
Nelson, Christopher, Gemberling, Matthew, Hakim, Chady H., Ousterout, David G., Thakore, Pratiksha I., Castellanos, Ruth M., Madhavan, Sarina, Pan, Xiufang, Ran, F. Ann, Yan, Winston, Asokan, Aravind, Zhang, Feng, Duan, Dongsheng, Gersbach, Charles A.
Published in Molecular therapy (01.05.2016)
Published in Molecular therapy (01.05.2016)
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