NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice
Marín‐Aguilar, Fabiola, Lechuga‐Vieco, Ana V., Alcocer‐Gómez, Elísabet, Castejón‐Vega, Beatriz, Lucas, Javier, Garrido, Carlos, Peralta‐Garcia, Alejandro, Pérez‐Pulido, Antonio J., Varela‐López, Alfonso, Quiles, José L., Ryffel, Bernhard, Flores, Ignacio, Bullón, Pedro, Ruiz‐Cabello, Jesús, Cordero, Mario D.
Published in Aging cell (01.01.2020)
Published in Aging cell (01.01.2020)
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Nutraceutical Compounds Targeting Inflammasomes in Human Diseases
Castejón-Vega, Beatriz, Giampieri, Francesca, Alvarez-Suarez, José M
Published in International journal of molecular sciences (08.07.2020)
Published in International journal of molecular sciences (08.07.2020)
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Inhibition of the NLRP3 inflammasome improves lifespan in animal murine model of Hutchinson–Gilford Progeria
González‐Dominguez, Alvaro, Montañez, Raúl, Castejón‐Vega, Beatriz, Nuñez‐Vasco, Jéssica, Lendines‐Cordero, Débora, Wang, Chun, Mbalaviele, Gabriel, Navarro‐Pando, José M, Alcocer‐Gómez, Elísabet, Cordero, Mario D
Published in EMBO molecular medicine (07.10.2021)
Published in EMBO molecular medicine (07.10.2021)
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Modulatory effect of Andean blackberry polyphenols on genes related to antioxidant and inflammatory responses, the NLRP3 inflammasome, and autophagy
Castejón-Vega, Beatriz, Kyriakidis, Nikolaos C., Alcócer-Gómez, Elizabet, Giampieri, Francesca, González-Paramás, Ana M., Cordero, Mario D., Alvarez-Suarez, José M.
Published in Journal of berry research (19.03.2024)
Published in Journal of berry research (19.03.2024)
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Inhibition of the NLRP3 inflammasome prevents ovarian aging
Navarro-Pando, José M, Alcocer-Gómez, Elísabet, Castejón-Vega, Beatriz, Navarro-Villarán, Elena, Condés-Hervás, Mónica, Mundi-Roldan, María, Muntané, Jordi, Pérez-Pulido, Antonio J, Bullon, Pedro, Wang, Chun, Hoffman, Hal M, Sanz, Alberto, Mbalaviele, Gabriel, Ryffel, Bernhard, Cordero, Mario D
Published in Science advances (01.01.2021)
Published in Science advances (01.01.2021)
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Integrated molecular signaling involving mitochondrial dysfunction and alteration of cell metabolism induced by tyrosine kinase inhibitors in cancer
Rodríguez-Hernández, María A., de la Cruz-Ojeda, P, López-Grueso, Mª José, Navarro-Villarán, Elena, Requejo-Aguilar, Raquel, Castejón-Vega, Beatriz, Negrete, María, Gallego, Paloma, Vega-Ochoa, Álvaro, Victor, Victor M., Cordero, Mario D., Del Campo, José A., Bárcena, J. Antonio, Padilla, C. Alicia, Muntané, Jordi
Published in Redox biology (01.09.2020)
Published in Redox biology (01.09.2020)
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Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells
Villanueva-Paz, Marina, Cordero, Mario D, Pavón, Ana Delgado, Vega, Beatriz Castejón, Cotán, David, De la Mata, Mario, Oropesa-Ávila, Manuel, Alcocer-Gomez, Elizabet, de Lavera, Isabel, Garrido-Maraver, Juan, Carrascosa, José, Zaderenko, Ana Paula, Muntané, Jordi, de Miguel, Manuel, Sánchez-Alcázar, José Antonio
Published in Genes & cancer (01.07.2016)
Published in Genes & cancer (01.07.2016)
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Potential Role of the Mitochondria for the Dermatological Treatment of Papillon-Lefèvre
Castejón-Vega, Beatriz, Battino, Maurizio, Quiles, José L, Bullon, Beatriz, Cordero, Mario D, Bullón, Pedro
Published in Antioxidants (01.01.2021)
Published in Antioxidants (01.01.2021)
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L-Arginine Ameliorates Defective Autophagy in GM2 Gangliosidoses by mTOR Modulation
Castejón-Vega, Beatriz, Rubio, Alejandro, Pérez-Pulido, Antonio J, Quiles, José L, Lane, Jon D, Fernández-Domínguez, Beatriz, Cachón-González, María Begoña, Martín-Ruiz, Carmen, Sanz, Alberto, Cox, Timothy M, Alcocer-Gómez, Elísabet, Cordero, Mario D
Published in Cells (Basel, Switzerland) (11.11.2021)
Published in Cells (Basel, Switzerland) (11.11.2021)
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Inflammasomes in Clinical Practice: A Brief Introduction
Alcocer-Gómez, Elísabet, Castejón-Vega, Beatriz, López-Sánchez, Macarena, Cordero, Mario D
Published in Experientia supplementum (2012) (01.01.2018)
Published in Experientia supplementum (2012) (01.01.2018)
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Journal Article
NLRP3 Inflammasome Inhibition by MCC950 in Aged Mice Improves Health via Enhanced Autophagy and PPARα Activity
Marín-Aguilar, Fabiola, Castejón-Vega, Beatriz, Alcocer-Gómez, Elísabet, Lendines-Cordero, Debora, Cooper, Matthew A, de la Cruz, Patricia, Andújar-Pulido, Eloísa, Pérez-Alegre, Mónica, Muntané, Jordi, Pérez-Pulido, Antonio J, Ryffel, Bernhard, Robertson, Avril A B, Ruiz-Cabello, Jesús, Bullón, Pedro, Cordero, Mario D
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (13.07.2020)
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (13.07.2020)
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Autophagic dysfunction in patients with Papillon-Lefèvre syndrome is restored by recombinant cathepsin C treatment
Bullón, Pedro, Castejón-Vega, Beatriz, Román-Malo, Lourdes, Jimenez-Guerrero, María Paz, Cotán, David, Forbes-Hernandez, Tamara Y., Varela-López, Alfonso, Pérez-Pulido, Antonio J., Giampieri, Francesca, Quiles, José L., Battino, Maurizio, Sánchez-Alcázar, José A., Cordero, Mario D.
Published in Journal of allergy and clinical immunology (01.10.2018)
Published in Journal of allergy and clinical immunology (01.10.2018)
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A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart
Nicolás-Ávila, José A., Lechuga-Vieco, Ana V., Esteban-Martínez, Lorena, Sánchez-Díaz, María, Díaz-García, Elena, Santiago, Demetrio J., Rubio-Ponce, Andrea, Li, Jackson LiangYao, Balachander, Akhila, Quintana, Juan A., Martínez-de-Mena, Raquel, Castejón-Vega, Beatriz, Pun-García, Andrés, Través, Paqui G., Bonzón-Kulichenko, Elena, García-Marqués, Fernando, Cussó, Lorena, A-González, Noelia, González-Guerra, Andrés, Roche-Molina, Marta, Martin-Salamanca, Sandra, Crainiciuc, Georgiana, Guzmán, Gabriela, Larrazabal, Jagoba, Herrero-Galán, Elías, Alegre-Cebollada, Jorge, Lemke, Greg, Rothlin, Carla V., Jimenez-Borreguero, Luis Jesús, Reyes, Guillermo, Castrillo, Antonio, Desco, Manuel, Muñoz-Cánoves, Pura, Ibáñez, Borja, Torres, Miguel, Ng, Lai Guan, Priori, Silvia G., Bueno, Héctor, Vázquez, Jesús, Cordero, Mario D., Bernal, Juan A., Enríquez, José A., Hidalgo, Andrés
Published in Cell (01.10.2020)
Published in Cell (01.10.2020)
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Blockade of the NLRP3 inflammasome improves metabolic health and lifespan in obese mice
Cañadas-Lozano, Diego, Marín-Aguilar, Fabiola, Castejón-Vega, Beatriz, Ryffel, Bernhard, Navarro-Pando, José M., Ruiz-Cabello, Jesús, Alcocer-Gómez, Elísabet, Bullón, Pedro, Cordero, Mario D.
Published in GeroScience (01.04.2020)
Published in GeroScience (01.04.2020)
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Journal Article
NLRP3 inflammasome inhibition rescues Hutchinson-Gilford Progeria cellular phenotype and extend longevity of an animal model
Alcocer-Gómez, Elísabet, Castejón-Vega, Beatriz, Nuñez-Vasco, Jéssica, Lendines-Cordero, Débora, Navarro-Pando, José M, Cordero, Mario D
Published in bioRxiv (10.09.2020)
Published in bioRxiv (10.09.2020)
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