Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments
Janiszewska, Michalina, Tabassum, Doris P., Castaño, Zafira, Cristea, Simona, Yamamoto, Kimiyo N., Kingston, Natalie L., Murphy, Katherine C., Shu, Shaokun, Harper, Nicholas W., Del Alcazar, Carlos Gil, Alečković, Maša, Ekram, Muhammad B., Cohen, Ofir, Kwak, Minsuk, Qin, Yuanbo, Laszewski, Tyler, Luoma, Adrienne, Marusyk, Andriy, Wucherpfennig, Kai W., Wagle, Nikhil, Fan, Rong, Michor, Franziska, McAllister, Sandra S., Polyak, Kornelia
Published in Nature cell biology (01.07.2019)
Published in Nature cell biology (01.07.2019)
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Journal Article
IL-1β inflammatory response driven by primary breast cancer prevents metastasis-initiating cell colonization
Castaño, Zafira, San Juan, Beatriz P., Spiegel, Asaf, Pant, Ayush, DeCristo, Molly J., Laszewski, Tyler, Ubellacker, Jessalyn M., Janssen, Susanne R., Dongre, Anushka, Reinhardt, Ferenc, Henderson, Ayana, del Rio, Ana Garcia, Gifford, Ann M., Herbert, Zachary T., Hutchinson, John N., Weinberg, Robert A., Chaffer, Christine L., McAllister, Sandra S.
Published in Nature cell biology (01.09.2018)
Published in Nature cell biology (01.09.2018)
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Journal Article
Anti-tumor effects of RTX-240: an engineered red blood cell expressing 4-1BB ligand and interleukin-15
McArdel, Shannon L., Dugast, Anne-Sophie, Hoover, Maegan E., Bollampalli, Arjun, Hong, Enping, Castano, Zafira, Leonard, Shannon Curtis, Pawar, Sneha, Mellen, Jennifer, Muriuki, Kelvin, McLaughlin, Douglas C., Bayhi, Nicholas, Carpenter, Christopher L., Turka, Laurence A., Wickham, Thomas J., Elloul, Sivan
Published in Cancer Immunology, Immunotherapy (01.09.2021)
Published in Cancer Immunology, Immunotherapy (01.09.2021)
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Journal Article
208 RTX-224, an engineered allogeneic red cell therapeutic expressing 4–1BBL and IL-12, activates immune cells in blood and spleen to promote tumor growth inhibition in mice
Dugast, Anne-Sophie, McArdel, Shannon, Castano, Zafira, Hoover, Maegan, Bollampalli, Arjun Reddy, Hong, Enping, Leonard, Shannon, Pepi, Ryan, Nanna, Alex, Turka, Laurence, Elloul, Sivan
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
Identification of luminal breast cancers that establish a tumor-supportive macroenvironment defined by proangiogenic platelets and bone marrow-derived cells
Kuznetsov, Hanna S, Marsh, Timothy, Markens, Beth A, Castaño, Zafira, Greene-Colozzi, April, Hay, Samantha A, Brown, Victoria E, Richardson, Andrea L, Signoretti, Sabina, Battinelli, Elisabeth M, McAllister, Sandra S
Published in Cancer discovery (01.12.2012)
Published in Cancer discovery (01.12.2012)
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Journal Article
The bed and the bugs: Interactions between the tumor microenvironment and cancer stem cells
Castaño, Zafira, Fillmore, Christine M, Kim, Carla F, McAllister, Sandra S
Published in Seminars in cancer biology (01.10.2012)
Published in Seminars in cancer biology (01.10.2012)
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Journal Article
Loss of RasGAP Tumor Suppressors Underlies the Aggressive Nature of Luminal B Breast Cancers
Olsen, Sarah Naomi, Wronski, Ania, Castaño, Zafira, Dake, Benjamin, Malone, Clare, De Raedt, Thomas, Enos, Miriam, DeRose, Yoko S, Zhou, Wenhui, Guerra, Stephanie, Loda, Massimo, Welm, Alana, Partridge, Ann H, McAllister, Sandra S, Kuperwasser, Charlotte, Cichowski, Karen
Published in Cancer discovery (01.02.2017)
Published in Cancer discovery (01.02.2017)
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Journal Article
Stromal EGF and igf-I together modulate plasticity of disseminated triple-negative breast tumors
Castaño, Zafira, Marsh, Timothy, Tadipatri, Ramya, Kuznetsov, Hanna S, Al-Shahrour, Fatima, Paktinat, Mahnaz, Greene-Colozzi, April, Nilsson, Björn, Richardson, Andrea L, McAllister, Sandra S
Published in Cancer discovery (01.08.2013)
Published in Cancer discovery (01.08.2013)
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Journal Article
neuron-specific isoform of glycogen synthase kinase-3β is required for axon growth
Castaño, Zafira, Gordon-Weeks, Phillip R, Kypta, Robert M
Published in Journal of neurochemistry (01.04.2010)
Published in Journal of neurochemistry (01.04.2010)
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Journal Article
Expression of complement factor H by lung cancer cells: Effects on the activation of the alternative pathway of complement
AJONA, Daniel, CASTANO, Zafira, GARAYOA, Mercedes, ZUDAIRE, Enrique, PAJARES, Maria J, MARTINEZ, Alfredo, CUTTITTA, Frank, MONTUENGA, Luis M, PIO, Ruben
Published in Cancer research (Chicago, Ill.) (01.09.2004)
Published in Cancer research (Chicago, Ill.) (01.09.2004)
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Journal Article
Abstract PR13: Understanding the systemic interactions between primary tumors and disseminated tumor initiating cells
Castano, Zafira, Chaffer, Christine L., Spiegel, Asaf, Pant, Ayush, Richardson, Andrea L., Reinhardt, Ferenc, Marsh, Timothy, Janssen, Susanne, Gifford, Ann M., Weinberg, Robert A., McAllister, Sandra S.
Published in Cancer research (Chicago, Ill.) (01.08.2016)
Published in Cancer research (Chicago, Ill.) (01.08.2016)
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Journal Article
International mentoring as a new educational approach to alleviate brain drain, empower young talent, and internationalize higher education
Soriano-Carot, María, Bretón-Romero, Rosa, López-Herraiz, Joaquín, López-Diego, Rocío, Suárez-Fueyo, Abel, Prades, Gemma Pellissa, Fernandez-Godino, Rosario, Navarro-Gomez, Daniel, Saguar, Amaranta, Nieto, David, Sánchez-García, Laura, Peropadre, Borja, Castano, Zafira
Published in Nature biotechnology (01.03.2017)
Published in Nature biotechnology (01.03.2017)
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Journal Article
αCP-4, encoded by a putative tumor suppressor gene at 3p21, but not its alternative splice variant αCP-4a, is underexpressed in lung cancer
PIO, Ruben, ZUDAIRE, Isabel, CALASANZ, Maria J, MONTUENGA, Luis M, PINO, Irene, CASTANO, Zafira, ZABALEGUI, Natalia, VICENT, Silvestre, GARCIA-AMIGOT, Fermin, ODERO, Maria D, LOZANO, Maria D, GARCIA-FONCILLAS, Jesus
Published in Cancer research (Chicago, Ill.) (15.06.2004)
Published in Cancer research (Chicago, Ill.) (15.06.2004)
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Journal Article
Abstract 4861: Triple-negative breast cancers establish a systemic environment that drives malignant progression of otherwise indolent disseminated tumors via EGF and IGF
Castano, Zafira, Marsh, Timothy, Tadipatri, Ramya, Kuznetsov, Hanna, Al-Sahour, Fatima, Paktinaz, Mahnaz, McAllister, Sandra S.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
The neuron-specific isoform of glycogen synthase kinase-3b is required for axon growth
Castano, Zafira, Gordon-Weeks, Phillip R, Kypta, Robert M
Published in Journal of neurochemistry (01.04.2010)
Published in Journal of neurochemistry (01.04.2010)
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Journal Article