Mechanism of cleavage of alpha-synuclein by the 20S proteasome and modulation of its degradation by the RedOx state of the N-terminal methionines
Alvarez-Castelao, Beatriz, Goethals, Marc, Vandekerckhove, Joël, Castaño, José G.
Published in Biochimica et biophysica acta (01.02.2014)
Published in Biochimica et biophysica acta (01.02.2014)
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Journal Article
Synphilin-1 inhibits alpha-synuclein degradation by the proteasome
Alvarez-Castelao, Beatriz, Castaño, José G.
Published in Cellular and molecular life sciences : CMLS (01.08.2011)
Published in Cellular and molecular life sciences : CMLS (01.08.2011)
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Journal Article
Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain
Díaz‐Hernández, Miguel, Valera, Adriana G., Morán, María A., Gómez‐Ramos, Pilar, Alvarez‐Castelao, Beatriz, Castaño, José G., Hernández, Félix, Lucas, José J.
Published in Journal of neurochemistry (01.09.2006)
Published in Journal of neurochemistry (01.09.2006)
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Journal Article
Protein degradation in a LAMP-2-deficient B-lymphoblastoid cell line from a patient with Danon disease
Sánchez-Lanzas, Raul, Alvarez-Castelao, Beatriz, Bermejo, Teresa, Ayuso, Teresa, Tuñón, Teresa, Castaño, José G.
Published in Biochimica et biophysica acta (01.08.2016)
Published in Biochimica et biophysica acta (01.08.2016)
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Journal Article
Neuronal Induction of the Immunoproteasome in Huntington's Disease
Diaz-Hernandez, Miguel, Hernandez, Felix, Martin-Aparicio, Ester, Gomez-Ramos, Pilar, Moran, Maria A, Castano, Jose G, Ferrer, Isidro, Avila, Jesus, Lucas, Jose J
Published in The Journal of neuroscience (17.12.2003)
Published in The Journal of neuroscience (17.12.2003)
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Journal Article
Reduced protein stability of human DJ-1/PARK7 L166P, linked to autosomal recessive Parkinson disease, is due to direct endoproteolytic cleavage by the proteasome
Alvarez-Castelao, Beatriz, Muñoz, Carolina, Sánchez, Isabel, Goethals, Marc, Vandekerckhove, Joël, Castaño, José G.
Published in Biochimica et biophysica acta (01.02.2012)
Published in Biochimica et biophysica acta (01.02.2012)
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Journal Article
α-Synuclein expression levels do not significantly affect proteasome function and expression in mice and stably transfected PC12 cell lines
Martìn-Clemente, Begoña, Alvarez-Castelao, Beatriz, Mayo, Isabel, Sierra, Ana Belén, Díaz, Virginia, Milán, Miguel, Fariñas, Isabel, Gómez-Isla, Teresa, Ferrer, Isidro, Castaño, José G.
Published in The Journal of biological chemistry (22.04.2016)
Published in The Journal of biological chemistry (22.04.2016)
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Journal Article
Epitope Mapping of Antibodies to Alpha-Synuclein in LRRK2 Mutation Carriers, Idiopathic Parkinson Disease Patients, and Healthy Controls
Alvarez-Castelao, Beatriz, Gorostidi, Ana, Ruíz-Martínez, Javier, López de Munain, Adolfo, Castaño, José G
Published in Frontiers in aging neuroscience (15.07.2014)
Published in Frontiers in aging neuroscience (15.07.2014)
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Journal Article
Cytomegalovirus Promoter Up-regulation Is the Major Cause of Increased Protein Levels of Unstable Reporter Proteins after Treatment of Living Cells with Proteasome Inhibitors
Alvarez-Castelao, Beatriz, Martín-Guerrero, Idoia, García-Orad, África, Castaño, José G.
Published in The Journal of biological chemistry (09.10.2009)
Published in The Journal of biological chemistry (09.10.2009)
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Journal Article
α-Synuclein Expression Levels Do Not Significantly Affect Proteasome Function and Expression in Mice and Stably Transfected PC12 Cell Lines
Martìn-Clemente, Begoña, Alvarez-Castelao, Beatriz, Mayo, Isabel, Sierra, Ana Belén, Dìaz, Virginia, Milán, Miguel, Fariñas, Isabel, Gómez-Isla, Teresa, Ferrer, Isidro, Castaño, José G.
Published in The Journal of biological chemistry (17.12.2004)
Published in The Journal of biological chemistry (17.12.2004)
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Journal Article
The proteasome is a major autoantigen in multiple sclerosis
Mayo, Isabel, Arribas, Joaquín, Villoslada, Pablo, Alvarez DoForno, Rita, Rodríguez‐Vilariño, Susana, Montalban, Xavier, de Sagarra, María Rosa, Castaño, José G.
Published in Brain (London, England : 1878) (01.12.2002)
Published in Brain (London, England : 1878) (01.12.2002)
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Journal Article
CCAAT/Enhancer binding protein β silencing mitigates glial activation and neurodegeneration in a rat model of Parkinson’s disease
Morales-Garcia, Jose A., Gine, Elena, Hernandez-Encinas, Elena, Aguilar-Morante, Diana, Sierra-Magro, Ana, Sanz-SanCristobal, Marina, Alonso-Gil, Sandra, Sanchez-Lanzas, Raul, Castaño, Jose G., Santos, Angel, Perez-Castillo, Ana
Published in Scientific reports (19.10.2017)
Published in Scientific reports (19.10.2017)
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Journal Article
Proteasome dynamics during cell cycle in rat Schwann cells
Lafarga, Miguel, Fernández, Rosario, Mayo, Isabel, Berciano, María T., Castaño, José G.
Published in Glia (01.06.2002)
Published in Glia (01.06.2002)
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Journal Article
Parkin deficiency increases the resistance of midbrain neurons and glia to mild proteasome inhibition: the role of autophagy and glutathione homeostasis
Casarejos, Maria J., Solano, Rosa M., Rodriguez‐Navarro, José A., Gómez, Ana, Perucho, Juan, Castaño, Jose G., De Yébenes, Justo García, Mena, Maria A.
Published in Journal of neurochemistry (01.09.2009)
Published in Journal of neurochemistry (01.09.2009)
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