Overcoming ABC transporter-mediated multidrug resistance: The dual role of tyrosine kinase inhibitors as multitargeting agents
Beretta, Giovanni Luca, Cassinelli, Giuliana, Pennati, Marzia, Zuco, Valentina, Gatti, Laura
Published in European journal of medicinal chemistry (15.12.2017)
Published in European journal of medicinal chemistry (15.12.2017)
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Beyond targeting amplified MDM2 and CDK4 in well differentiated and dedifferentiated liposarcomas: From promise and clinical applications towards identification of progression drivers
Cassinelli, Giuliana, Pasquali, Sandro, Lanzi, Cinzia
Published in Frontiers in oncology (02.09.2022)
Published in Frontiers in oncology (02.09.2022)
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Journal Article
Targeting the Akt kinase to modulate survival, invasiveness and drug resistance of cancer cells
Cassinelli, Giuliana, Zuco, Valentina, Gatti, Laura, Lanzi, Cinzia, Zaffaroni, Nadia, Colombo, Diego, Perego, Paola
Published in Current medicinal chemistry (01.05.2013)
Published in Current medicinal chemistry (01.05.2013)
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Journal Article
Upregulation of ERK-EGR1-heparanase axis by HDAC inhibitors provides targets for rational therapeutic intervention in synovial sarcoma
Lanzi, Cinzia, Favini, Enrica, Dal Bo, Laura, Tortoreto, Monica, Arrighetti, Noemi, Zaffaroni, Nadia, Cassinelli, Giuliana
Published in Journal of experimental & clinical cancer research (02.12.2021)
Published in Journal of experimental & clinical cancer research (02.12.2021)
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Journal Article
miR-199a-3p displays tumor suppressor functions in papillary thyroid carcinoma
Minna, Emanuela, Romeo, Paola, De Cecco, Loris, Dugo, Matteo, Cassinelli, Giuliana, Pilotti, Silvana, Degl'Innocenti, Debora, Lanzi, Cinzia, Casalini, Patrizia, Pierotti, Marco A, Greco, Angela, Borrello, Maria Grazia
Published in Oncotarget (15.05.2014)
Published in Oncotarget (15.05.2014)
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Journal Article
Differential outcome of MEK1/2 inhibitor-platinum combinations in platinum-sensitive and -resistant ovarian carcinoma cells
Cossa, Giacomo, Lanzi, Cinzia, Cassinelli, Giuliana, Carenini, Nives, Arrighetti, Noemi, Gatti, Laura, Corna, Elisabetta, Zunino, Franco, Zaffaroni, Nadia, Perego, Paola
Published in Cancer letters (01.06.2014)
Published in Cancer letters (01.06.2014)
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Journal Article
Induction of a Proinflammatory Program in Normal Human Thyrocytes by the RET/PTC1 Oncogene
Maria Grazia Borrello, Luisella Alberti, Andrew Fischer, Debora Degl'Innocenti, Cristina Ferrario, Gariboldi, Manuela, Federica Marchesi, Paola Allavena, Greco, Angela, Paola Collini, Silvana Pilotti, Giuliana Cassinelli, Paola Bressan, Laura Fugazzola, Mantovani, Alberto, Pierotti, Marco A.
Published in Proceedings of the National Academy of Sciences - PNAS (11.10.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (11.10.2005)
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Journal Article
Identification of MET and SRC Activation in Melanoma Cell Lines Showing Primary Resistance to PLX4032
Vergani, Elisabetta, Vallacchi, Viviana, Frigerio, Simona, Deho, Paola, Mondellini, Piera, Perego, Paola, Cassinelli, Giuliana, Lanzi, Cinzia, Testi, Maria Adele, Rivoltini, Licia, Bongarzone, Italia, Rodolfo, Monica
Published in Neoplasia (New York, N.Y.) (01.12.2011)
Published in Neoplasia (New York, N.Y.) (01.12.2011)
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Journal Article
Overactive IGF1/Insulin Receptors and NRASQ61R Mutation Drive Mechanisms of Resistance to Pazopanib and Define Rational Combination Strategies to Treat Synovial Sarcoma
Lanzi, Cinzia, Dal Bo, Laura, Favini, Enrica, Tortoreto, Monica, Beretta, Giovanni Luca, Arrighetti, Noemi, Zaffaroni, Nadia, Cassinelli, Giuliana
Published in Cancers (22.03.2019)
Published in Cancers (22.03.2019)
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Journal Article
Dasatinib reduces FAK phosphorylation increasing the effects of RPI-1 inhibition in a RET/PTC1-expressing cell line
Caccia, Dario, Miccichè, Francesca, Cassinelli, Giuliana, Mondellini, Piera, Casalini, Patrizia, Bongarzone, Italia
Published in Molecular cancer (18.10.2010)
Published in Molecular cancer (18.10.2010)
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Journal Article
PLK1 is a critical determinant of tumor cell sensitivity to CPT11 and its inhibition enhances the drug antitumor efficacy in squamous cell carcinoma models sensitive and resistant to camptothecins
Zuco, Valentina, De Cesare, Michelandrea, Zaffaroni, Nadia, Lanzi, Cinzia, Cassinelli, Giuliana
Published in Oncotarget (20.04.2015)
Published in Oncotarget (20.04.2015)
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Journal Article
DUSP6/MKP3 is overexpressed in papillary and poorly differentiated thyroid carcinoma and contributes to neoplastic properties of thyroid cancer cells
Degl'Innocenti, Debora, Romeo, Paola, Tarantino, Eva, Sensi, Marialuisa, Cassinelli, Giuliana, Catalano, Veronica, Lanzi, Cinzia, Perrone, Federica, Pilotti, Silvana, Seregni, Ettore, Pierotti, Marco A, Greco, Angela, Borrello, Maria Grazia
Published in Endocrine-related cancer (01.02.2013)
Published in Endocrine-related cancer (01.02.2013)
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Journal Article
Synergistic Cooperation Between Sunitinib and Cisplatin Promotes Apoptotic Cell Death in Human Medullary Thyroid Cancer
Lopergolo, Alessia, Nicolini, Valentina, Favini, Enrica, Dal Bo, Laura, Tortoreto, Monica, Cominetti, Denis, Folini, Marco, Perego, Paola, Castiglioni, Vittoria, Scanziani, Eugenio, Borrello, Maria Grazia, Zaffaroni, Nadia, Cassinelli, Giuliana, Lanzi, Cinzia
Published in The journal of clinical endocrinology and metabolism (01.02.2014)
Published in The journal of clinical endocrinology and metabolism (01.02.2014)
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Journal Article
Functional Mapping of Receptor Tyrosine Kinases in Myxoid Liposarcoma
NEGRI, Tiziana, VIRDIS, Emanuela, CASALINI, Patrizia, GRECO, Angela, PIEROTTI, Marco A, PILOTTI, Silvana, BRICH, Silvia, BOZZI, Fabio, TAMBORINI, Elena, TARANTINO, Eva, JOCOLLE, Genny, CASSINELLI, Giuliana, GROSSO, Federica, SANFILIPPO, Roberta
Published in Clinical cancer research (15.07.2010)
Published in Clinical cancer research (15.07.2010)
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Journal Article
RET/PTC1-Driven Neoplastic Transformation and Proinvasive Phenotype of Human Thyrocytes Involve Met Induction and β-Catenin Nuclear Translocation
Cassinelli, Giuliana, Favini, Enrica, Degl'Innocenti, Debora, Salvi, Alessandro, De Petro, Giuseppina, Pierotti, Marco A., Zunino, Franco, Borrello, Maria Grazia, Lanzi, Cinzia
Published in Neoplasia (New York, N.Y.) (01.01.2009)
Published in Neoplasia (New York, N.Y.) (01.01.2009)
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