CD38 expression and complement inhibitors affect response and resistance to daratumumab therapy in myeloma
Nijhof, Inger S., Casneuf, Tineke, van Velzen, Jeroen, van Kessel, Berris, Axel, Amy E., Syed, Khaja, Groen, Richard W.J., van Duin, Mark, Sonneveld, Pieter, Minnema, Monique C., Zweegman, Sonja, Chiu, Christopher, Bloem, Andries C., Mutis, Tuna, Lokhorst, Henk M., Sasser, A.Kate, van de Donk, Niels W.C.J.
Published in Blood (18.08.2016)
Published in Blood (18.08.2016)
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Daratumumab plus bortezomib and dexamethasone versus bortezomib and dexamethasone in relapsed or refractory multiple myeloma: updated analysis of CASTOR
Spencer, Andrew, Lentzsch, Suzanne, Weisel, Katja, Avet-Loiseau, Hervé, Mark, Tomer M, Spicka, Ivan, Masszi, Tamas, Lauri, Birgitta, Levin, Mark-David, Bosi, Alberto, Hungria, Vania, Cavo, Michele, Lee, Je-Jung, Nooka, Ajay K, Quach, Hang, Lee, Cindy, Barreto, Wolney, Corradini, Paolo, Min, Chang-Ki, Scott, Emma C, Chanan-Khan, Asher A, Horvath, Noemi, Capra, Marcelo, Beksac, Meral, Ovilla, Roberto, Jo, Jae-Cheol, Shin, Ho-Jin, Sonneveld, Pieter, Soong, David, Casneuf, Tineke, Chiu, Christopher, Amin, Himal, Qi, Ming, Thiyagarajah, Piruntha, Sasser, A Kate, Schecter, Jordan M, Mateos, Maria-Victoria
Published in Haematologica (Roma) (01.12.2018)
Published in Haematologica (Roma) (01.12.2018)
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Daratumumab plus lenalidomide and dexamethasone versus lenalidomide and dexamethasone in relapsed or refractory multiple myeloma: updated analysis of POLLUX
Dimopoulos, Meletios A, San-Miguel, Jesus, Belch, Andrew, White, Darrell, Benboubker, Lotfi, Cook, Gordon, Leiba, Merav, Morton, James, Ho, P Joy, Kim, Kihyun, Takezako, Naoki, Moreau, Philippe, Kaufman, Jonathan L, Sutherland, Heather J, Lalancette, Marc, Magen, Hila, Iida, Shinsuke, Kim, Jin Seok, Prince, H Miles, Cochrane, Tara, Oriol, Albert, Bahlis, Nizar J, Chari, Ajai, O' Rourke, Lisa, Wu, Kaida, Schecter, Jordan M, Casneuf, Tineke, Chiu, Christopher, Soong, David, Sasser, A Kate, Khokhar, Nushmia Z, Avet-Loiseau, Hervé, Usmani, Saad Z
Published in Haematologica (Roma) (01.12.2018)
Published in Haematologica (Roma) (01.12.2018)
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Deep immune profiling of patients treated with lenalidomide and dexamethasone with or without daratumumab
Casneuf, Tineke, Adams, Homer C., van de Donk, Niels W.C.J., Abraham, Yann, Bald, Jaime, Vanhoof, Greet, Van der Borght, Koen, Smets, Tina, Foulk, Brad, Nielsen, Karl C., Rusbuldt, Joshua, Axel, Amy, Lysaght, Andrew, Ceulemans, Hugo, Stevenaert, Frederik, Usmani, Saad Z., Plesner, Torben, Avet-Loiseau, Herve, Nijhof, Inger, Mutis, Tuna, Schecter, Jordan M., Chiu, Christopher, Bahlis, Nizar J.
Published in Leukemia (01.02.2021)
Published in Leukemia (01.02.2021)
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Modeling gene and genome duplications in eukaryotes
Maere, S, Bodt, S. de, Raes, J, Casneuf, T, Montagu, M. van, Kuiper, M, Peer, Y. van de
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.2005)
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Genetic subtypes of smoldering multiple myeloma are associated with distinct pathogenic phenotypes and clinical outcomes
Bustoros, Mark, Anand, Shankara, Sklavenitis-Pistofidis, Romanos, Redd, Robert, Boyle, Eileen M., Zhitomirsky, Benny, Dunford, Andrew J., Tai, Yu-Tzu, Chavda, Selina J., Boehner, Cody, Neuse, Carl Jannes, Rahmat, Mahshid, Dutta, Ankit, Casneuf, Tineke, Verona, Raluca, Kastritis, Efstathis, Trippa, Lorenzo, Stewart, Chip, Walker, Brian A., Davies, Faith E., Dimopoulos, Meletios-Athanasios, Bergsagel, P. Leif, Yong, Kwee, Morgan, Gareth J., Aguet, François, Getz, Gad, Ghobrial, Irene M.
Published in Nature communications (15.06.2022)
Published in Nature communications (15.06.2022)
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Effects of daratumumab on natural killer cells and impact on clinical outcomes in relapsed or refractory multiple myeloma
Casneuf, Tineke, Xu, Xu Steven, Adams, Homer C., Axel, Amy E., Chiu, Christopher, Khan, Imran, Ahmadi, Tahamtan, Yan, Xiaoyu, Lonial, Sagar, Plesner, Torben, Lokhorst, Henk M., van de Donk, Niels W.C.J., Clemens, Pamela L., Sasser, A. Kate
Published in Blood advances (24.10.2017)
Published in Blood advances (24.10.2017)
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Daratumumab, bortezomib, and dexamethasone in relapsed or refractory multiple myeloma: subgroup analysis of CASTOR based on cytogenetic risk
Weisel, Katja, Spencer, Andrew, Lentzsch, Suzanne, Avet-Loiseau, Hervé, Mark, Tomer M, Spicka, Ivan, Masszi, Tamas, Lauri, Birgitta, Levin, Mark-David, Bosi, Alberto, Hungria, Vania, Cavo, Michele, Lee, Je-Jung, Nooka, Ajay, Quach, Hang, Munder, Markus, Lee, Cindy, Barreto, Wolney, Corradini, Paolo, Min, Chang-Ki, Chanan-Khan, Asher A, Horvath, Noemi, Capra, Marcelo, Beksac, Meral, Ovilla, Roberto, Jo, Jae-Cheol, Shin, Ho-Jin, Sonneveld, Pieter, Casneuf, Tineke, DeAngelis, Nikki, Amin, Himal, Ukropec, Jon, Kobos, Rachel, Mateos, Maria-Victoria
Published in Journal of hematology and oncology (20.08.2020)
Published in Journal of hematology and oncology (20.08.2020)
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Journal Article
Daratumumab, lenalidomide, and dexamethasone in relapsed/refractory myeloma: a cytogenetic subgroup analysis of POLLUX
Kaufman, Jonathan L., Dimopoulos, Meletios A., White, Darrell, Benboubker, Lotfi, Cook, Gordon, Leiba, Merav, Morton, James, Joy Ho, P., Kim, Kihyun, Takezako, Naoki, Moreau, Philippe, Sutherland, Heather J., Magen, Hila, Iida, Shinsuke, Kim, Jin Seok, Miles Prince, H., Cochrane, Tara, Oriol, Albert, Bahlis, Nizar J., Chari, Ajai, O’Rourke, Lisa, Trivedi, Sonali, Casneuf, Tineke, Krevvata, Maria, Ukropec, Jon, Kobos, Rachel, Avet-Loiseau, Hervé, Usmani, Saad Z., San-Miguel, Jesus
Published in Blood cancer journal (New York) (03.11.2020)
Published in Blood cancer journal (New York) (03.11.2020)
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NK Cell Phenotype Is Associated With Response and Resistance to Daratumumab in Relapsed/Refractory Multiple Myeloma
Verkleij, Christie P.M., Frerichs, Kristine A., Broekmans, Marloes E.C., Duetz, Carolien, O'Neill, Chloe A., Bruins, Wassilis S.C., Homan‐Weert, Paola M., Minnema, Monique C., Levin, Mark‐David, Broijl, Annemiek, Bos, Gerard M.J., Kersten, Marie José, Klein, Saskia K., Shikhagaie, Medya M., Casneuf, Tineke, Abraham, Yann, Smets, Tina, Vanhoof, Greet, Cortes‐Selva, Diana, Steenbergen, Laure, Ramos, Elena, Verona, Raluca I., Krevvata, Maria, Sonneveld, Pieter, Zweegman, Sonja, Mutis, Tuna, Donk, Niels W.C.J.
Published in HemaSphere (01.05.2023)
Published in HemaSphere (01.05.2023)
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IL6 sensitizes prostate cancer to the antiproliferative effect of IFNα2 through IRF9
Erb, Holger H H, Langlechner, Regina V, Moser, Patrizia L, Handle, Florian, Casneuf, Tineke, Verstraeten, Karin, Schlick, Bettina, Schäfer, Georg, Hall, Brett, Sasser, Kate, Culig, Zoran, Santer, Frédéric R
Published in Endocrine-related cancer (01.10.2013)
Published in Endocrine-related cancer (01.10.2013)
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Deep sustained response to daratumumab monotherapy associated with T-cell expansion in triple refractory myeloma
Usmani, Saad Z, Khan, Imran, Chiu, Christopher, Foureau, David, Druhan, Lawrence J, Rigby, Katherine, Casneuf, Tineke, Sasser, A Kate
Published in Experimental hematology & oncology (07.02.2018)
Published in Experimental hematology & oncology (07.02.2018)
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Daratumumab depletes CD38+ immune regulatory cells, promotes T-cell expansion, and skews T-cell repertoire in multiple myeloma
Krejcik, Jakub, Casneuf, Tineke, Nijhof, Inger S., Verbist, Bie, Bald, Jaime, Plesner, Torben, Syed, Khaja, Liu, Kevin, van de Donk, Niels W.C.J., Weiss, Brendan M., Ahmadi, Tahamtan, Lokhorst, Henk M., Mutis, Tuna, Sasser, A.Kate
Published in Blood (21.07.2016)
Published in Blood (21.07.2016)
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Evaluation of sustained minimal residual disease negativity with daratumumab-combination regimens in relapsed and/or refractory multiple myeloma: analysis of POLLUX and CASTOR
Avet-Loiseau, Hervé, San-Miguel, Jesus, Casneuf, Tineke, Iida, Shinsuke, Lonial, Sagar, Usmani, Saad Z, Spencer, Andrew, Moreau, Philippe, Plesner, Torben, Weisel, Katja, Ukropec, Jon, Chiu, Christopher, Trivedi, Sonali, Amin, Himal, Krevvata, Maria, Ramaswami, Priya, Qin, Xiang, Qi, Mia, Sun, Steven, Qi, Ming, Kobos, Rachel, Bahlis, Nizar J
Published in Journal of clinical oncology (01.04.2021)
Published in Journal of clinical oncology (01.04.2021)
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Genomic Profiling of Smoldering Multiple Myeloma Identifies Patients at a High Risk of Disease Progression
Bustoros, Mark, Sklavenitis-Pistofidis, Romanos, Park, Jihye, Redd, Robert, Zhitomirsky, Benny, Dunford, Andrew J, Salem, Karma, Tai, Yu-Tzu, Anand, Shankara, Mouhieddine, Tarek H, Chavda, Selina J, Boehner, Cody, Elagina, Liudmila, Neuse, Carl Jannes, Cha, Justin, Rahmat, Mahshid, Taylor-Weiner, Amaro, Van Allen, Eliezer, Kumar, Shaji, Kastritis, Efstathis, Leshchiner, Ignaty, Morgan, Elizabeth A, Laubach, Jacob, Casneuf, Tineke, Richardson, Paul, Munshi, Nikhil C, Anderson, Kenneth C, Trippa, Lorenzo, Aguet, François, Stewart, Chip, Dimopoulos, Meletios-Athanasios, Yong, Kwee, Bergsagel, P Leif, Manier, Salomon, Getz, Gad, Ghobrial, Irene M
Published in Journal of clinical oncology (20.07.2020)
Published in Journal of clinical oncology (20.07.2020)
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Journal Article
High‐Parameter Mass Cytometry Evaluation of Relapsed/Refractory Multiple Myeloma Patients Treated with Daratumumab Demonstrates Immune Modulation as a Novel Mechanism of Action
Adams, Homer C., Stevenaert, Frederik, Krejcik, Jakub, Van der Borght, Koen, Smets, Tina, Bald, Jaime, Abraham, Yann, Ceulemans, Hugo, Chiu, Christopher, Vanhoof, Greet, Usmani, Saad Z., Plesner, Torben, Lonial, Sagar, Nijhof, Inger, Lokhorst, Henk M., Mutis, Tuna, Donk, Niels W.C.J., Sasser, Amy Kate, Casneuf, Tineke
Published in Cytometry. Part A (01.03.2019)
Published in Cytometry. Part A (01.03.2019)
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A phase 2 multicentre study of siltuximab, an anti‐interleukin‐6 monoclonal antibody, in patients with relapsed or refractory multiple myeloma
Voorhees, Peter M., Manges, Robert F., Sonneveld, Pieter, Jagannath, Sundar, Somlo, George, Krishnan, Amrita, Lentzsch, Suzanne, Frank, Richard C., Zweegman, Sonja, Wijermans, Pierre W., Orlowski, Robert Z., Kranenburg, Britte, Hall, Brett, Casneuf, Tineke, Qin, Xiang, Velde, Helgi, Xie, Hong, Thomas, Sheeba K.
Published in British journal of haematology (01.05.2013)
Published in British journal of haematology (01.05.2013)
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CD38 IMMUNE MODULATION AND TREATMENT OF SOLID TUMORS WITH ANTIBODIES THAT SPECIFICALLY BIND CD38
AHMADI TAHAMTAN, SASSER AMY, LOKHORST HENK M, CASNEUF TINEKE, MUTIS TUNA
Year of Publication 15.10.2024
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Year of Publication 15.10.2024
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