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Published in Leukemia (01.09.2014)
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Combination of the MEK inhibitor pimasertib with BTK or PI3K-delta inhibitors is active in preclinical models of aggressive lymphomas
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The RNA helicase DDX21 cooperates with ETS1 and FLI1 in cell cycle regulation and small nucleolar RNA processing to sustain the survival of DLBCL cells
Sartori, G., Priebe, V., Cascione, L., Favre‐Juilland, M., Chung, E. Y., Napoli, S., Arribas, A., Rinaldi, A., Miazza, M. Thome, Bertoni, F.
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Ceriani, L., Milan, L., Cascione, L., Di Rocco, A., Kryachok, I., Davies, A. J., Stathis, A., Johnson, P.W.M., Ciccone, G., Martelli, M., Zucca, E.
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IL16 PRODUCTION IS A MECHANISM OF RESISTANCE TO BTK INHIBITORS AND TO R‐CHOP
Arribas, A., Napoli, S., Cascione, L., Sartori, G., Cannas, E., Tarantelli, C., Spriano, F., Gaudio, E., Zucchetto, A., Rossi, F. M., Rinaldi, A., Castro de Moura, M., Jovic, S., Pittau, R. Bordone, Stathis, A., Stussi, G., Gattei, V., Brown, J. R., Esteller, M., Zucca, E., Rossi, D., Bertoni, F.
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THE TRANSCRIPTION FACTOR FLI1 SUSTAINS RELEVANT BIOLOGICAL PATHWAYS AND DRIVES ONCOGENES THAT PROMOTE CELL GROWTH IN DIFFUSE LARGE B‐CELL LYMPHOMA (DLBCL)
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Identification of a nanostring signature that differentiates early pancreatic cancers according to stromal composition and predicts clinical outcome
Sclafani, F., Cascione, L., Cunningham, D., Young, K., Carotenuto, P., Fassan, M., Salati, M., Lanese, A., Berenguer Pina, J., Kouvelakis, K., Vendrell, I., Said-Huntingford, I., Previdi, M., Begum, R., Gillbanks, A., Hedayat, S., Sadanandam, A., Lampis, A., Hahne, J., Valeri, N., Chau, I., Braconi, C.
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SIMULTANEOUS BET/CREBBP/EP300 TARGETING APPROACH COMPARED TO SINGLE BET OR CREBBP/EP300 INHIBITION IN DIFFUSE LARGE B‐CELL LYMPHOMA (DLBCL)
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Published in Hematological oncology (01.06.2019)
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The novel mTORC1/2 inhibitor PQR620 has in vitro and in vivo activity in lymphomas
Tarantelli, C, Gaudio, E, Hillmann, P, Spriano, F, Rinaldi, A, Kwee, I, Cascione, L, Fabbro, D, Stathis, A, Zucca, E, Cmiljanovic, V, Bertoni, F
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A COMPLETELY GENETIC PROGNOSTIC MODEL OVERCOMES CLINICAL PROGNOSTICATORS IN MANTLE CELL LYMPHOMA: RESULTS FROM THE MCL0208 TRIAL FROM THE FONDAZIONE ITALIANA LINFOMI (FIL)
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EARLY PROGRESSION OF DISEASE (POD24) PREDICTS SHORTER SURVIVAL IN MALT LYMPHOMA PATIENTS RECEIVING SYSTEMIC TREATMENT
Conconi, A., Thieblemont, C., Cascione, L., Torri, V., Kiesewetter, B., Margiotta‐Casaluci, G., Gaidano, G., Raderer, M., Cavalli, F., Lopez Guillermo, A., Johnson, P.W., Zucca, E.
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THE ANTI‐CD25 ANTIBODY‐DRUG CONJUGATE CAMIDANLUMAB TESIRINE (ADCT‐301) PRESENTS A STRONG PRECLINICAL ACTIVITY BOTH AS SINGLE AGENT AND IN COMBINATION IN LYMPHOMA CELL LINES
Spriano, F., Tarantelli, C., Golino, G., Gaudio, E., Scalise, L., Cascione, L., Zucca, E., Van Berkel, P., Stathis, A., Zammarchi, F., Bertoni, F.
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THE NONCODING RNA GECPAR IS INVOLVED IN WNT SIGNALING AND HAS TUMOR‐SUPPRESSOR ACTIVITY IN DIFFUSE LARGE B CELL LYMPHOMA
Napoli, S., Cascione, L., Rinaldi, A., Sartori, G., Forcato, M., Bicciato, S., Chiappella, A., Ghione, P., Elemento, O., Inghirami, G., Bertoni, F.
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GENETIC AND PHENOTYPIC ATTRIBUTES OF SPLENIC MARGINAL ZONE LYMPHOMA
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Trisomy 12 CLLs progress through NOTCH1 mutations
Balatti, V, Lerner, S, Rizzotto, L, Rassenti, L Z, Bottoni, A, Palamarchuk, A, Cascione, L, Alder, H, Keating, M J, Kipps, T J, Pekarsky, Y, Croce, C M
Published in Leukemia (01.03.2013)
Published in Leukemia (01.03.2013)
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COPANLISIB SYNERGIES WITH CONVENTIONAL AND TARGETED AGENTS INCLUDING VENETOCLAX IN PRECLINICAL MODELS OF B‐ AND T‐CELL LYMPHOMAS
Tarantelli, C., Lange, M., Gaudio, E., Cascione, L., Spriano, F., Kwee, I., Arribas, A., Rinaldi, A., Jourdan, T., Berthold, M., Margheriti, F., Gritti, G., Rossi, D., Stathis, A., Liu, N., Zucca, E., Politz, O., Bertoni, F.
Published in Hematological oncology (01.06.2019)
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MECHANISMS OF SECONDARY RESISTANCE TO IDELALISIB IN MARGINAL ZONE LYMPHOMA
Arribas, A., Napoli, S., Gaudio, E., Cascione, L., Di Veroli, A., Tarantelli, C., Spriano, F., Zucchetto, A., Rossi, F., Rinaldi, A., Stathis, A., Stussi, G., Gattei, V., Cruciani, G., Zucca, E., Rossi, D., Bertoni, F.
Published in Hematological oncology (01.06.2019)
Published in Hematological oncology (01.06.2019)
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THE FIRST‐IN‐CLASS ETS INHIBITOR TK‐216 INTERFERES WITH ETS TRANSCRIPTION FACTORS AND SYNERGIZE WITH LENALIDOMIDE IN LYMPHOMA
Spriano, F., Chung, E., Napoli, S., Tarantelli, C., Gaudio, E., Cascione, L., Cavalli, A., Rinaldi, A., Kwee, I., Ye, H., Rossi, D., Zucca, E., Stathis, A., Jessen, K., Lannutti, B., Toretsky, J., Bertoni, F.
Published in Hematological oncology (01.06.2019)
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HSP-90 Inhibition is a Promising Therapeutic Strategy in Cholangiocarcinoma and MIR-21 may Serve as a Biomarker of Sensitivity
Lampis, A, Cascione, L, Burke, R, Clarke, P, Simbolo, M, Scarpa, A, Bosma, E, Yu, S, Cole, R, Stubbs, M, Sharp, S, van Montfort, R, Hahne, J, Fassan, M, Workman, P, Valeri, N, Braconi, C
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Published in Journal of hepatology (2016)
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EG‐011 IS A NOVEL SMALL MOLECULE WITH IN VITRO AND IN VIVO ANTI‐TUMOR ACTIVITY AGAINST LYMPHOMA
Gaudio, E., Spriano, F., Tarantelli, C., Guala, M., Riveiro, E., Golino, G., Lupia, A., Costa, G., Rocca, R., Cascione, L., Jenni, S., Tsai, Y., Bornhauser, B., Alcaro, S., Paduano, F., Trapasso, F., Zucca, E., Stathis, A., Pazzi, N., Cavalli, F., Bertoni, F.
Published in Hematological oncology (01.06.2019)
Published in Hematological oncology (01.06.2019)
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