Post-translational Modifications of OLIG2 Regulate Glioma Invasion through the TGF-β Pathway
Singh, Shiv K., Fiorelli, Roberto, Kupp, Robert, Rajan, Sindhu, Szeto, Emily, Lo Cascio, Costanza, Maire, Cecile L., Sun, Yu, Alberta, John A., Eschbacher, Jennifer M., Ligon, Keith L., Berens, Michael E., Sanai, Nader, Mehta, Shwetal
Published in Cell reports (Cambridge) (26.07.2016)
Published in Cell reports (Cambridge) (26.07.2016)
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Journal Article
Developmentally regulated signaling pathways in glioma invasion
Mehta, Shwetal, Lo Cascio, Costanza
Published in Cellular and molecular life sciences : CMLS (01.02.2018)
Published in Cellular and molecular life sciences : CMLS (01.02.2018)
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Journal Article
Nonredundant, isoform-specific roles of HDAC1 in glioma stem cells
Lo Cascio, Costanza, McNamara, James B, Melendez, Ernesto L, Lewis, Erika M, Dufault, Matthew E, Sanai, Nader, Plaisier, Christopher L, Mehta, Shwetal
Published in JCI insight (08.09.2021)
Published in JCI insight (08.09.2021)
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Journal Article
Quisinostat is a brain-penetrant radiosensitizer in glioblastoma
Lo Cascio, Costanza, Margaryan, Tigran, Luna-Melendez, Ernesto, McNamara, James B, White, Connor I, Knight, William, Ganta, Saisrinidhi, Opachich, Zorana, Cantoni, Claudia, Yoo, Wonsuk, Sanai, Nader, Tovmasyan, Artak, Mehta, Shwetal
Published in JCI insight (22.11.2023)
Published in JCI insight (22.11.2023)
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Journal Article
Developmentally regulated signaling pathways in glioma invasion
Mehta, Shwetal, Lo Cascio, Costanza
Published in Cellular and molecular life sciences : CMLS (01.02.2018)
Published in Cellular and molecular life sciences : CMLS (01.02.2018)
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Journal Article
Investigating the Interactions of Glioma Stem Cells in the Perivascular Niche at Single‐Cell Resolution using a Microfluidic Tumor Microenvironment Model
Adjei‐Sowah, Emmanuela A., O'Connor, Samantha A., Veldhuizen, Jaimeson, Lo Cascio, Costanza, Plaisier, Christopher, Mehta, Shwetal, Nikkhah, Mehdi
Published in Advanced science (01.07.2022)
Published in Advanced science (01.07.2022)
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Journal Article
Post-translational Modifications of OLIG2 Regulate Glioma Invasion through the TGF-β Pathway
Singh, Shiv K., Fiorelli, Roberto, Kupp, Robert, Rajan, Sindhu, Szeto, Emily, Lo Cascio, Costanza, Maire, Cecile L., Sun, Yu, Alberta, John A., Eschbacher, Jennifer M., Ligon, Keith L., Berens, Michael E., Sanai, Nader, Mehta, Shwetal
Published in Cell reports (Cambridge) (13.06.2017)
Published in Cell reports (Cambridge) (13.06.2017)
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Journal Article
STEM-25. HDAC1 IS ESSENTIAL FOR GLIOMA STEM CELL SURVIVAL
Lo Cascio, Costanza, McNamara, James, Luna Melendez, Ernesto, Mehta, Shwetal
Published in Neuro-oncology (Charlottesville, Va.) (11.11.2019)
Published in Neuro-oncology (Charlottesville, Va.) (11.11.2019)
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Journal Article
STEM-15. STAT5-OLIG2 TRANSCRIPTIONAL COMPLEX MEDIATES GLIOMA STEM CELL SELF RENEWAL AND INVASION
Miller, Aunay, Cascio, Costanza Lo, Blomquist, Mylan, McNamara, James, Orndorff, Keely, Dufault, Matthew, Sereduk, Christopher, Loftus, Joseph, Mehta, Shwetal, Tran, Nhan
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
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Journal Article
EXTH-24. TUMOR PHARMACOKINETICS, PHARMACODYNAMICS AND RADIATION SENSITIZATION IN PATIENT-DERIVED XENOGRAFT MODELS OF GLIOBLASTOMA TREATED WITH THE SECOND-GENERATION HDAC INHIBITOR, QUISINOSTAT
Lo Cascio, Costanza, Margaryan, Tigran, Melendez, Ernesto Luna, McNamara, James, Knight, William, Himes, Sarah, Sanai, Nader, Tovmasyan, Artak, Mehta, Shwetal
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
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Journal Article
STEM-19. NON-REDUNDANT, ISOFORM-SPECIFIC ROLES OF HDAC1 IN THE REGULATION OF THE GLIOMA STEM CELL PHENOTYPE
Cascio, Costanza Lo, McNamara, James, Melendez, Ernesto Luna, Lewis, Erika, Dufault, Matthew, Sanai, Nader, Plaisier, Christopher, Mehta, Shwetal
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
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Journal Article
CNSC-05. THE GABAERGIC INTERNEURONAL AND NEURAL PROGENITOR LINEAGE OF THE DIFFUSE HEMISPHERIC GLIOMA, H3 G34-MUTANT, SHOW CALCIUM EVENTS IN THE FORM OF INTERCELLULAR WAVES AND SPONTANEOUS ELECTRICAL ACTIVITY
Cruzeiro, Gustavo Alencastro Veiga, Cascio, Costanza Lo, Neyazi, Sina, Junior, Carlos Alberto Oliveira Biagi, Haase, Rebecca, Nascimento, Andrezza, Frederico, Stephen Charles, Sarnow, Katharina, Venkataramani, Varun, Liu, Ilon, Huang, Kun, Tang, Xin, Segal, Rosalind, Monje, Michelle, Filbin, Mariella
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
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Journal Article
EXTH-30. PHARMACOKINETICS- AND PHARMACODYNAMICS-BASED EVALUATION OF QUISINOSTAT AS A RADIOSENSITIZER IN PRECLINICAL MODELS OF GBM
Cascio, Costanza Lo, Margaryan, Tigran, Melendez, Ernesto Luna, McNamara, James, Knight, William, White, Connor, Opachich, Zorana, Ganta, Niddhi, Giff, Alexis, Sanai, Nader, Tovmasyan, Artak, Mehta, Shwetal
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
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Journal Article
STEM-15. RADIATION-INDUCED MODULATION OF NEURODEVELOPMENTAL PATHWAYS IN CLASSICAL GLIOMA STEM CELLS
Lo Cascio, Costanza, Luna Melendez, Ernesto, McNamara, James, Schultz, Robert, Tien, An-Chi, Plaisier, Christopher, Mehta, Shwetal
Published in Neuro-oncology (Charlottesville, Va.) (11.11.2019)
Published in Neuro-oncology (Charlottesville, Va.) (11.11.2019)
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Journal Article
Abstract 3222: Acute and long-term responses to treatment with the HDAC inhibitor quisinostat in preclinical models of glioblastoma
Orndorff, Keely, McNamara, James, Stavnichuk, Mariya, Cascio, Costanza Lo, White, Connor, Melendez, Ernesto Luna, Uzunalli, Gozde, Sanai, Nader, Mehta, Shwetal
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract 256: A novel transcriptional complex of OLIG2-STAT5 mediates glioma stem cell self renewal and invasion
Miller, Aunay, Lo Cascio, Costanza, Blomquist, Mylan, McNamara, James B., Orndorff, Keely, Dufault, Matthew, Sereduk, Christopher, Loftus, Joseph, Mehta, Shwetal, Tran, Nhan L.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract 510: A novel role for Olig2 in the regulation of glioma invasion
Singh, Shiv K., Giannonatti, Nicole, Kupp, Robert, Cascio, Costanza Lo, Mehta, Shwetal
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article